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Cilengitide
Pronunciation
Definition 1
A substance that is being studied as an anticancer and antiangiogenesis drug. Also called EMD 121974. (NCI Dictionary)
Definition 2
A cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI Thesaurus)
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