| Health / Medical Topics |
Cyclopentenyl Cytosine
A pro-drug carbocyclic analogue of cytidine with antineoplastic and antiviral activities. Cyclopentenyl cytosine (CPEC) is converted to the active metabolite cyclopentenyl cytosine 5'-triphosphate (CPEC-TP); CPEC-TP competitively inhibits cytidine triphosphate (CTP) synthase, thereby depleting intracellular cytidine pools and inhibiting DNA and RNA synthesis. This agent may also induce differentiation of some tumor cell types. The antiviral activity of this agent is broad-spectrum. (NCI Thesaurus)
YOU MAY ALSO LIKE
An aromatic hydrocarbon that consists of five fused rings and is formed during the incomplete combustion of organic matter. Cyclopenta[c,d]pyrene is primarily…
A nonsteroidal anti-inflammatory drug used to relieve pain and inflammation. Cyclooxygenase-2 inhibitors are being studied in the prevention of colon polyps, and…
An enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to…
Cyclooxygenase Interaction involves temporary non-covalent binding, typically through intermolecular physical forces of attraction and spatial complementarity, between a molecular entity and Cyclooxygenase,…
COX inhibitor. A type of drug that is used to treat inflammation and pain, and is being studied in the prevention and…
An enzyme that converts arachidonic acid into biologically active prostanoids, such as prostaglandins, prostacyclins, and thromboxanes.
