CYP19A1 wt Allele

Human CYP19A1 wild-type allele is located in the vicinity of 15q21.1 and is approximately 114 kb in length. This allele, which encodes cytochrome P450 19A1 protein, is involved in the biosynthesis of estrogen. Certain allelic variants of the CYP19A1 gene exhibit functional mutations that result in enhanced aromatase activity which, in turn, causes familial gynecomastia. (NCI Thesaurus)

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CYP19A1 Gene

This gene is involved in development and estrogen metabolism.

CYP17A1 wt Allele

Human CYP17A1 wild-type allele is located in the vicinity of 10q24.3 and is approximately 7 kb in length. This allele, which encodes…

CYP17A1 Gene

This gene plays a role in the metabolism of estrogen and glucocorticoids. It is also involved in sexual maturation.

CYP17 Inhibitor CFG920

An orally available inhibitor of the steroid 17-alpha-hydroxylase/C17,20 lyase (CYP17A1 or CYP17), with potential antiandrogen and antineoplastic activities. Upon oral administration, CYP17…

CYP11B2 wt Allele

Human CYP11B2 wild-type allele is located within 8q21-q22 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B2,…

CYP11B2 Gene

This gene is involved in mineralocorticoid metabolism.