Ehlers-Danlos Syndrome

Definition 1

An inherited connective tissue disorder characterized by loose and fragile skin and joint hypermobility. (NCI Thesaurus)

Definition 2

A heterogeneous group of inherited collagen diseases. The most common manifestations of Ehlers-Danlos Syndrome are hyperextensible skin and joints, skin fragility and reduced wound healing capability. (NLM, Medical Subject Headings)

More information

Ehlers-Danlos syndrome (EDS) is a group of inherited disorders that weaken connective tissues. Connective tissues are proteins that support skin, bones, blood vessels, and other organs.

EDS usually affects your skin, joints and blood vessel walls. Symptoms include

• Loose joints
• Fragile, small blood vessels
• Abnormal scar formation and wound healing
• Soft, velvety, stretchy skin that bruises easily

There are several types of EDS. They can range from mild to life-threatening. About 1 in 5,000 people has EDS. There is no cure. Treatment involves managing symptoms, often with medicines and physical therapy. It also includes learning how to protect your joints and prevent injuries. (NIH)

Also called: Cutis elastica, EDS

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