Eltrombopag

Pronunciation

Definition 1

The active ingredient in a drug used to treat chronic immune thrombocytopenic purpura (a condition in which platelets are destroyed by the immune system). It causes more platelets to be made in the bone marrow. It is also being studied in the treatment of low platelet counts caused by chemotherapy. It is a type of thrombopoietin receptor agonist. (NCI Dictionary)

Definition 2

An orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity. Eltrombopag binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of megakaryocytes, thereby increasing the production of blood platelets. (NCI Thesaurus)

YOU MAY ALSO LIKE

Elspar

A drug that is used to treat acute lymphoblastic leukemia (ALL) and is being studied in the treatment of some other types…

Elsiglutide

A synthetic glucagon-like peptide-2 (GLP-2) analogue with potential antidiarrheal and intestinotrophic activities. Upon subcutaneous administration, elsiglutide, a 39 amino acid polypeptide, binds…

Elsamitrucin

An heterocyclic antineoplastic antibiotic isolated from the bacterium Actinomycete strain J907-21. Elsamitrucin intercalates into DNA at guanine-cytosine (G-C)-rich sequences and inhibits…

Eloxatin

A drug used with other drugs to treat colorectal cancer that is advanced or has come back. It is also being studied…

Elotuzumab

A humanized monoclonal antibody directed against the human CS1 (CD2 subset 1, CRACC, SLAMF7) antigen with potential antineoplastic activity. Elotuzumab binds to…

Eloquent Brain Areas

Areas of the brain that control speech, motor functions, and sensory processing which are required for an individual to understand and interact…