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Endostatin
Pronunciation
Definition 1
A substance being studied in the treatment of cancer. Endostatin is made from a type of collagen (a protein found in cartilage and other connective tissue). It may prevent the growth of new blood vessels that tumors need to grow. Endostatin is a type of antiangiogenesis agent. Also called COL18A1. (NCI Dictionary)
Definition 2
Endostatin (183 aa, ~20 kDa) is encoded by the human COL18A1 gene. This protein fragment is involved in the inhibition of both endothelial cell proliferation and blood vessel formation. (NCI Thesaurus)
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