| Health / Medical Topics |
EP-2101
Definition 1
A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called cancer vaccines. (NCI Dictionary)
Definition 2
A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. EP-2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes. (NCI Thesaurus)
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