| Health / Medical Topics |
EPHX1 wt Allele
Human EPHX1 wild-type allele is located in the vicinity of 1q42.1 and is approximately 35 kb in length. This allele, which encodes epoxide hydrolase 1 protein, is involved in the metabolism of both arene and aliphatic epoxides. Certain allelic variants of the EPHX1 gene confer susceptibility to lymphoproliferative disorders. Specific inherited defects in this gene also cause familial hypercholanemia. An EPHX1 low-activity genotype is associated with decreased risk of lung cancer. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in both the activation and detoxification of xenobiotics.
Ephrin-B2 (333 aa, ~37 kDa) is encoded by the human EFNB2 gene. This protein is involved in cell-cell communication.
A family of glycosylphosphatidylinositol (GPI)-anchored proteins that are involved in forward and reverse cell-cell signaling through binding to ephrin-A receptors (EPHA). …
Ephrin type-B receptor 3 (998 aa, ~110 kDa) is encoded by the human EPHB3 gene. This protein plays a role in cell-cell…
Ephrin type-B receptor 2 (1055 aa, ~117 kDa) is encoded by the human EPHB2 gene. This protein is involved in ephrin-B binding,…
Ephrin type-B receptor 1 (984 aa, ~110 kDa) is encoded by the human EPHB1 gene. This protein plays a role in both…
