Health / Medical Topics

    ERBB4 wt Allele

    Human ERBB4 wild-type allele is located within 2q33.3-q34 and is approximately 1156 kb in length. This allele, which encodes receptor tyrosine-protein kinase erbB-4 protein, is involved in the regulation of mitogenesis and differentiation. Mutations in this gene and overexpression are associated with several cancers, including breast cancer. (NCI Thesaurus)




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