| Health / Medical Topics |
ErbB Receptor Family Protein
A family of cellular proteins encoded by the c-erbB genes, including epidermal growth factor receptor. They are normally expressed in a variety of tissues of epithelial, mesenchymal, and neuronal origin. They are overexpressed in a significant portion of adenocarcinomas found at various sites, especially in the breast. Gene amplification appears to be the predominant method leading to overexpression. (NCI Thesaurus)
YOU MAY ALSO LIKE
The ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular signaling pathways regulating diverse biologic…
A toxic substance linked to an antibody that attaches to tumor cells and kills them.
Retrovirus-associated DNA sequences originally isolated from, or related to, the avian erythroblastosis virus (AEV). The c-erbA proto-oncogene encodes the thyroid hormone receptors,…
A structural analogue of erastin with potential antineoplastic activity. Erastin analogue PRLX 93936 appears to inhibit mitochondrial outer membrane protein VDACs (voltage-dependent…
A type of read only memory device that can be written to after manufacture, erased, and reused.
The lovegrass genus (Eragrostis) of the Poaceae (grass family) is the namesake of the tribe Eragrostideae. It would remain therein as long…
