ERG wt Allele

Human ERG wild-type allele is located in the vicinity of 21q22.3 and is approximately 280 kb in length. This allele, which encodes transcriptional regulator ERG protein, is involved in both the regulation of RNA polymerase II-directed transcription and the modification of local chromatin structure. Acute myelogenous leukemia of the subtype M2 is linked to the chromosomal translocation t(8;21)(q22;q22), which involves this gene and the EWSR1 gene. Human myeloid leukemia is linked to the chromosomal translocation t(16;21)(p11;q22) of this gene with the FUS gene. (NCI Thesaurus)

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ERG Gene

This gene plays a regulatory role in transcription, cellular maintenance and hematopoiesis.

Erg

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ERF wt Allele

Human ERF wild-type allele is located in the vicinity of 19q13 and is approximately 7 kb in length. This allele, which encodes…

ERF Gene

This gene plays a role in regulation of transcription and is putatively involved in carcinogenesis.

EREG wt Allele

Human EREG wild-type allele is located in the vicinity of 4q13.3 and is approximately 24 kb in length. This allele, which encodes…

EREG Gene

This gene plays a role in cellular biogenesis, organization and proliferation.