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Eribulin
Definition 1
An analogue of halichondrin B, a substance derived from a marine sponge (Lissodendoryx sp.) with antineoplastic activity. Eribulin binds to the vinca domain of tubulin and inhibits the polymerization of tubulin and the assembly of microtubules, resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest at G2/M phase, and, potentially, tumor regression. (NCI Thesaurus)
Definition 2
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called antitubulin agents. (NCI Dictionary)
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