Etaracizumab

Pronunciation

Definition 1

A substance being studied in the treatment of some types of cancer and other conditions. Etaracizumab binds to a protein on the surface of blood vessels and may prevent the growth of new blood vessels that tumors need to grow. It may also prevent the spread of cancer. It is a type of antiangiogenesis agent, a type of metastasis inhibitor, and a type of monoclonal antibody. Also called Abegrin, humanized monoclonal antibody MEDI-522, and MEDI-522. (NCI Dictionary)

Definition 2

A humanized monoclonal IgG1 antibody directed against the vitronectin receptor alpha v beta 3 integrin. Etaracizumab blocks the binding of ligands, such as vitronectin, to alpha v beta 3 integrin, resulting in inhibition of angiogenesis and metastasis. Alpha v beta 3 integrin is a cell adhesion and signaling receptor that is expressed on the surface of tumor vessel endothelial cells, some tumor cells, and a number of other cell types. (NCI Thesaurus)

YOU MAY ALSO LIKE

Etanidazole

A 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits glutathione transferase, thereby enhancing the cytotoxicity of ionizing radiation. This agent may…

Etanercept

A drug that is commonly used to treat arthritis. It is also being studied in the treatment of cancer, and as a…

Etalocib

A second-generation selective leukotriene B4 receptor (LTB4R) antagonist with potential antineoplastic activity. Although the exact underlying mechanism through which LY293111 exerts its…

Eta

The symbol for the linear predictor of a generalized linear model, and can also be used to denote the median of a…

ET-743

A substance that comes from a type of sea squirt and is being studied in the treatment of cancer. It binds to…

Eszopiclone

A nonbenzodiazepine, cyclopyrrolone and active stereoisomer of zopiclone with hypnotic and sedative activity and without significant anxiolytic activity. Although the exact mechanism…