| Health / Medical Topics |
Etrolizumab
A humanized monoclonal antibody targeting the beta7 subunit of the heterodimeric integrins alpha4beta7 and alphaEbeta7, with anti-inflammatory activity. Etrolizumab binds to the beta subunit of the alpha4beta7 and alphaEbeta7 integrins in the gastronintestinal tract blocking their activity. This prevents integrin-mediated leukocyte migration to and accumulation in sites of inflammation. (NCI Thesaurus)
YOU MAY ALSO LIKE
A synthetic oral retinoid that is a prodrug of acitretin. Etretinate activates retinoid receptors, causing an induction of cell differentiation, inhibition…
A diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the…
A long-acting loop diuretic. Etozolin appears to be rapidly metabolized to its active metabolite ozolinone.
A synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2…
A lipophilic, diaminopyrimidine folate antagonist with potential antineoplastic activity. Etoprine inhibits dihydrofolate reductase, resulting in decreased cellular folate metabolism. This may eventually…
A drug used to treat testicular and small cell lung cancers. It is also being studied in the treatment of several other…
