Health / Medical Topics

    EWSR1/ATF1 Fusion Gene

    A fusion gene that results from a chromosomal translocation t(12;22)(q13;q12) which fuses the first 7 or 8 exons of the EWSR1 gene on the 5' side of exon 4 or 5 of the ATF1 gene. This rearrangement is associated with both malignant clear cell sarcoma of the soft tissue and angiomatoid fibrous histiocytoma. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    Human EWSR1 wild-type allele is located in the vicinity of 22q12.2 and is approximately 32 kb in length. This allele, which encodes…
    This gene may play a role in post-transcriptional regulation; however the function remains to be elucidated. Mutations in the gene result in…
    An antisense oligonucleotide that targets the type 8 form of EWS/FLI-1, an oncogenic fusion gene found in Ewing's sarcoma and primitive neuro-ectodermal…
    The type 4 form of EWS/FLI-1, an oncogenic fusion gene found in Ewing's sarcoma and primitive neuro-ectodermal tumor (PNET). Resulting from a…
    The more potent transcription activator allele of a transforming chimeric gene resulting from a t(11;22) translocation that is found frequently in Ewing's…
    One allele of the transforming chimeric gene resulting from a t(11;22) translocation that is found frequently in patients with Ewing's sarcoma or…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact