Library / English Dictionary

    EXON

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Sequence of a gene's DNA that transcribes into protein structuresplay

    Example:

    exons are interspersed with introns

    Synonyms:

    coding DNA; exon

    Classified under:

    Nouns denoting substances

    Hypernyms ("exon" is a kind of...):

    deoxyribonucleic acid; desoxyribonucleic acid; DNA ((biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information)

    Antonym:

    intron (sequence of a eukaryotic gene's DNA that is not translated into a protein)

    Credits

     Context examples: 

    A fusion gene that results from a rearrangement of the q arm of chromosome 11 which fuses the exon 6 of the MLL gene to exon 8 of the CBL gene.

    (MLL/CBL Fusion Gene, NCI Thesaurus)

    A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13.1) which fuses the first 7 exons of the MLL gene to most of the coding sequence of the ELL gene.

    (MLL/ELL Fusion Gene, NCI Thesaurus)

    A fusion gene that results from a chromosomal translocation t(9;11)(q34;q23) which fuses exon 7 of the MLL gene to most of the FNBP1 gene.

    (MLL/FNBP1 Fusion Gene, NCI Thesaurus)

    A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13) which fuses the exon 6 of the MLL gene to most of the SH3GL1 gene.

    (MLL/SH3GL1 Fusion Gene, NCI Thesaurus)

    A fusion gene that results from a chromosomal translocation t(7;12)(q36;p13) which fuses the first exon of the MNX1 gene with exon 3 of the ETV6 gene.

    (MNX1/ETV6 Fusion Gene, NCI Thesaurus)

    A fusion gene that results from a chromosomal translocation t(11;12)(p15;p13) which fuses the first 13 exons of the NUP98 gene with exons 28-31 of the KDM5A gene.

    (NUP98/KDM5A Fusion Gene, NCI Thesaurus)

    A fusion gene (~1.9 kb) that results from a chromosomal translocation t(2;11)(q31;p15) which fuses the first twelve exons of the NUP98 gene with exon 2 of the HOXD13 gene.

    (NUP98/HOXD13 Fusion Gene, NCI Thesaurus)

    A fusion gene (~2.4 kb) that results from a chromosomal translocation t(11;17)(p15;p13) which fuses exon 13 of the NUP98 gene with exon 4 of the PHF23 gene.

    (NUP98/PHF23 Fusion Gene, NCI Thesaurus)

    A fusion gene that results from a chromosomal translocation t(11;18)(p15;q12) which fuses exon 12 of the NUP98 gene with exon 5 of the SETBP1 gene.

    (NUP98/SETBP1 Fusion Gene, NCI Thesaurus)

    A fusion gene that results from a chromosomal translocation t(11;20)(p15;q11) which fuses the first half of the NUP98 gene with exon 7 of the TOP1 gene.

    (NUP98/TOP1 Fusion Gene, NCI Thesaurus)


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