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GLYCOPROTEIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A conjugated protein having a carbohydrate component
Classified under:
Hypernyms ("glycoprotein" is a kind of...):
compound protein; conjugated protein (a protein complex combining amino acids with other substances)
Hyponyms (each of the following is a kind of "glycoprotein"):
mucin (a nitrogenous substance found in mucous secretions; a lubricant that protects body surfaces)
erythropoietin (a glycoprotein secreted by the kidneys that stimulates the production of red blood cells)
CD4; cluster of differentiation 4 (a glycoprotein that is found primarily on the surface of helper T cells)
CD8; cluster of differentiation 8 (a membrane glycoprotein that is found primarily on the surface of cytotoxic T cells)
lectin (any of several plant glycoproteins that act like specific antibodies but are not antibodies in that they are not evoked by an antigenic stimulus)
mucoid (any of several glycoproteins similar to mucin)
Context examples:
A murine and humanized monoclonal antibody that targets epitopes of epithelial glycoprotein mucin (MUC-1) on breast cancer surfaces.
(Monoclonal Antibody BrE-3, NCI Thesaurus)
FAP is a 95 kDa cell surface glycoprotein and an inducible tumour stromal antigen of epithelial cancers and of a subset of soft tissue sarcomas.
(Monoclonal Antibody F19, NCI Thesaurus)
MoAb T101 recognizes a 65kD glycoprotein, CD5 antigen, on the surface of T-cells.
(Monoclonal Antibody T101, NCI Thesaurus)
A humanized monoclonal antibody directed against the respiratory syncytial virus (RSV) fusion glycoprotein (F-protein), with activity against RSV.
(Motavizumab, NCI Thesaurus)
This gene is involved in endocytosis of glycoproteins by macrophages.
(MRC1 Gene, NCI Thesaurus)
This allele, which encodes macrophage mannose receptor 1 protein, plays a role in mediating endocytosis of glycoproteins by macrophages.
(MRC1 wt Allele, NCI Thesaurus)
When radiolabeled, this MoAb has potential use in the radioimaging or may induce a cytotoxic T-cell response against tumor cells that express this glycoprotein.
(Monoclonal Antibody MX35 F(ab')2, NCI Thesaurus)
A murine IgG2a monoclonal antibody that targets CD33, a 67-kD cell surface glycoprotein expressed on myeloid leukemia cells.
(Monoclonal Antibody M195, NCI Thesaurus)
A humanized monoclonal antibody directed against tumor-associated glycoprotein 72 (TAG72).
(Monoclonal Antibody hB72.3, NCI Thesaurus)
A humanized monoclonal antibody directed against MUC1, a mucin glycoprotein overexpressed in breast and other carcinomas.
(Monoclonal Antibody HuHMFG1, NCI Thesaurus)
