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HEPARIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A polysaccharide produced in basophils (especially in the lung and liver) and that inhibits the activity of thrombin in coagulation of the blood; it (trade names Lipo-Hepin and Liquaemin) is used as an anticoagulant in the treatment of thrombosis and in heart surgery
Synonyms:
heparin; Lipo-Hepin; Liquaemin
Classified under:
Nouns denoting man-made objects
Hypernyms ("heparin" is a kind of...):
anticoagulant; anticoagulant medication; decoagulant (medicine that prevents or retards the clotting of blood)
polyose; polysaccharide (any of a class of carbohydrates whose molecules contain chains of monosaccharide molecules)
Context examples:
A synthetic sulfated bis(lactobionic acid amide) derivative and heparin analogue with anticoagulant activity.
(Aprosulate, NCI Thesaurus)
A low molecular weight heparin (LMWH) composed of a heterogeneous mixture of sulfated polysaccharide glycosaminoglycan chains obtained by depolymerisation of porcine mucosal sodium heparin, extraction/purification and conversion to the calcium salt.
(Nadroparin Calcium, NCI Thesaurus)
This gene is involved in the heparin/heparin sulfate biosynthesis, cell organization/biogenesis and development of the cytoskeleton in chondrocytes.
(EXT2 Gene, NCI Thesaurus)
This protein plays a role in the promotion of proliferation and differentiation of chondrocytes and also mediates heparin- and divalent cation-dependent cell adhesion in many different cell types.
(Connective Tissue Growth Factor, NCI Thesaurus)
A specific anticoagulation activity of unfractionated or low molecular weight heparin on factor Xa, expressed as a number of international anti-Xa heparin units per one milliliter of plasma.
(Anti-Xa Activity International Unit per Milliliter, NCI Thesaurus)
A unit of anti-factor Xa anticoagulation activity of unfractionated or low molecular weight heparin.
(Anti-Coagulation Factor Xa Unit, NCI Thesaurus)
The sodium salt of bemiparin, a second generation, synthetic, low-molecular-weight heparin (LMWH) with anticoagulant activity.
(Bemiparin Sodium, NCI Thesaurus)
Anticoagulants, such as heparin or warfarin (also called Coumadin), work on chemical reactions in your body to lengthen the time it takes to form a blood clot.
(Blood Thinners, NIH)
Also required in the manufacture of amino acid taurine, Cysteine is a component of the antioxidant glutathione, and plays a role in the metabolism of essential biochemicals such as coenzyme A, heparin, and biotin.
(Cysteine, NCI Thesaurus)
This agent appears to inhibit the activity of sulfatase 2 (SULF2), a highly specific endoglucosamine-6-sulfatase that is overexpressed in the extracellular matrix of cancer cells and catalyzes the removal of sulfate from the 6-O-sulfate esters of heparin.
(PBN Derivative OKN-007, NCI Thesaurus)
