Health / Medical Topics

    HMGN1 wt Allele

    Human HMGN1 wild-type allele is located in the vicinity of 21q22.2 and is approximately 7 kb in length. This allele, which encodes nonhistone chromosomal protein HMG-14 protein, is involved in the modulation of chromatin modifications. The HMGN1 gene is overexpressed in Down syndrome. (NCI Thesaurus)




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