| Health / Medical Topics |
IFN Alpha Signaling Pathway
Interferon alpha plays a role in viral infections. Signaling takes place through an IFN receptor complex consisting of two alpha chains (type I receptor) complexed with Jak1 and Tyk2. These kinases phosphorylate Stat1 and Stat2 respectively. (NCI Thesaurus/BIOCARTA)
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Human IFITM1 wild-type allele is located in the vicinity of 11p15.5 and is approximately 1 kb in length. This allele, which encodes…
This gene is involved in the regulation of cell growth and proliferation. It also plays a role in immunity/defense.
