Medicine

A finding about one or more characteristics of genitourinary system cancer, following the rules of the TNM AJCC v6 classification system. … »
A finding about one or more characteristics of genitourinary system cancer, following the rules of the TNM AJCC v7 classification system. … »
An acute or chronic infectious process affecting any part of the genitourinary system. »
El material genético completo de un organismo. »
A single set of chromosomes and their genes; the genetic code for a particular individual. »
An annotated assembly of genome sequences created by the assimilation of data pieces from numerous sources. »
To analyse the entire genome (total genetic complement) of an individual, organism, cell or tissue. »
The ordered set of base-pairs that constitute the genetic code in a particular sample of DNA or RNA. »
A study that compares DNA markers across the genome (the complete genetic material in a person) in people with a disease or… »
The number of DNA sequence copies found over the entire genome of an individual. »
A measurable DNA or RNA characteristic that is an indicator of normal biologic processes, pathogenic processes, and/or response to therapeutic or other… »
A laboratory method that is used to learn about all the genes in a person or in a specific cell type, and… »
The DNA that is part of the normal chromosomal complement of an organism. »
The physical location on a specified chromosome of a feature or area of interest expressed as a base pair position. »
One or more characters and/or numbers that are used to identify, name, or characterize the nature, properties, or contents of genomic sequences,… »
Parent-specific expression or repression of genes or chromosomes in offspring. »
A biological process consisting of chromosomal rearrangements and duplications. These phenotypes are often seen in the karyotype of cancer cells, where there… »
A collection of DNA molecules, derived from restriction fragments that have been cloned in vectors, that includes all or part of the… »
The sequences, mRNA transcripts, protein products, or other genome encoded molecules of the cell. »
The orientation of a genomic element on the double stranded molecule. »
Information about all the genes in an organism, including variations, gene expression, and the way those genes interact with each other and… »
A laboratory method that is used to learn about all the genes in a person or in a specific cell type, and… »
Genomic segment extracted from a library e.g. BAC or YAC library to be used in the genetic manipulation of the animal… »
A laboratory method that is used to determine the entire genetic makeup of a specific organism or cell type. This method can… »
Estudio del material genético completo, incluso los genes y sus funciones, en un organismo. »
The study of the complete genetic material, including genes and their functions, of an organism. »
The Genomics and Proteomics Shared Resource is an integrated resource that provides genomic and proteomic technologies to the Cancer Center investigators for… »
The study of comprehensive sets of genes via high throughput methods. »
The Genomics Shared Resource provides Cancer Center researchers with support in areas of genetic and molecular biological analysis including DNA, RNA isolation,… »
An alternative to traditional gene therapy, genoplasty is a repair technology that uses short DNA fragments to induce a cell to repair… »
Exposure to DNA-damaging agents and subsequent energy expenditures by a cell to repair DNA damage. Genotoxic stress elicits biochemical responses that… »
A genotoxicity study that tests the ability of a substance to cause DNA damage not in intact animals, but in cells or… »
A genotoxicity study that tests the ability of a substance to cause DNA damage within the body. »
The genetic constitution of an organism or cell, as distinct from its expressed features or phenotype. »
Listing of the genetic changes made deliberately in order to generate the animal model. »
The process of assessing genetic variation present in an individual. »
A broad-spectrum aminoglycoside antibiotic produced by fermentation of Micromonospora purpurea or M. echinospora. Gentamicin is an antibiotic complex consisting of four major… »
One of the major components of the gentamicin complex. Gentamicin C1 has a methyl group in the 6' position of the 2-amino-hexose… »
One of the major components of the gentamicin complex. Gentamicin C1a lacks methyl groups on the 2-amino-hexose ring and has a free… »
One of the major components of the gentamicin complex. Gentamicin C2 has a methyl group at the 6' position of the 2-amino-hexose… »
The sulfate salt form of gentamycin, a broad-spectrum aminoglycoside antibiotic complex produced by the fermentation of Micromonospora purpurea or M. echinospora, with… »
A blue dye, extracted from plant of genus Gentiana, used in topical solution with antifungal and antimitotic properties. Gentian violet (GV) dissociates… »
In a manner that is soft and mild, having little impact. »
The anterior portion of the corpus callosum that bends downward and backward. »
An abnormal alignment of the knee backwards that is due to a deformity in the knee joint. »
A deformity of the legs characterized by medial angulation, resulting in a bow appearance. »
A taxonomic category ranking below a family (or Subfamily) and above a species and generally consisting of a group of species exhibiting… »
Of or relating to the science of geography; determined by geography. »
Any demarcated area of the Earth; may be determined by both natural and human boundaries. »
A system of hardware, software, and geographic data designed to capture, store, update, manipulate, analyze and display data that are linked to… »
The science that deals with the world and its inhabitants; a description of the earth, or a portion of the earth, including… »
Relative time scale based on stratigraphic position and correlation, and many different types of chronologic evidence. Geologic time is broken down into… »
A discrete, statistical distribution which is described by the probability density function: p(k) = p (1-p)^(k-1). It is the discreet analog of… »
The n-th root of the multiple products of n values, as contrasted with the normally understood arithmetic mean. »
The spatial outline of an object as described by the configuration of straight or curved lines. »
The mission of the Georgetown Lombardi Comprehensive Cancer Center is to improve the diagnosis, treatment, and prevention of cancer through innovative basic… »
A state in the southeastern United States. Its capital is Atlanta. »
A country in southwestern Asia, bordering the Black Sea, between Turkey and Russia. »
Gephyrin (736 aa, ~80 kDa) is encoded by the human GPHN gene. This protein is involved in biosynthesis of the molybdenum… »
Tipo de planta nativa del sur de África que tiene flores blancas, rosadas o rojas y hojas con 3 a 5… »
A terpene with two isoprene units head to tail with hydroxyl group attached to the head methyl group. The chemical structure is… »
A type of plant that is native to southern Africa and has white, pink, purple, or red flowers and 3- to 5-lobed… »
The essential oil of Pelargonium graveolens. Geranium oil is used primarily for its aromatic properties. »
Alpha-beta heterodimeric human GGTase-I transfers a geranylgeranyl moiety to the Cys of a C-terminal CAAX motif in candidate proteins as a means… »
Geranylgeranyl transferase type-1 subunit beta (377 aa, ~42 kDa) is encoded by the human PGGT1B gene. This protein plays a role in… »
A substance that inhibits protein geranylgeranyltransferase type 1 (GGTase-I), with potential antineoplastic activity. GGTase-I is involved in the posttranslational modification of a… »
A small mammal belonging to the Gerbillinae subfamily, this omnivorous rodent grows to be 6-12 inches in length, with the tail making… »
Your esophagus is the tube that carries food from your mouth to your stomach. Gastroesophageal reflux disease (GERD) happens when a muscle… »
Of or related to the aged or to characteristics of the aging process. »
A standardized rating scale developed by Yesavage et al in 1983, which is a self-report assessment used to identify depression in older… »
A standardized rating scale developed by Sheikh et al in 1986, which is a shorter version derived from the original GDS and… »
The branch of medical science that deals with diseases and problems specific to elderly people. »
A bacterium, virus, or other microorganism that can cause infection and disease. »
A reproductive cell of the body. Germ cells are egg cells in females and sperm cells in males. »
A type of tumor that begins in the cells that give rise to sperm or eggs. Germ cell tumors can occur almost… »
After the blastocyst stage of embryonic development, the inner cell mass of the blastocyst goes through gastrulation, a period when the inner… »
Free of bacteria, viruses, and other microorganisms that can cause infection and disease. »
Denotes the inhabitants of Germany, a person from there, or their descendants elsewhere. »
A plant whose daisy-like flowers are used in tea to calm and relax, improve sleep, and help stomach problems. German chamomile has… »
The German Federal Institute for Drugs and Medical Devices Commission E. A committee made up of scientists, toxicologists, doctors, and pharmacists formed… »
The German Pinscher, also called the Standard Pinscher, is a medium-sized, tall terrier with a smooth, glossy coat that comes in red… »
The German Shepherd Dog is also known as the Alsatian. It is well proportioned and very strong. The coat most often comes… »
The German Shorthaired Pointer is a clean-cut, well-balanced, hunting dog with a chiseled head and large nose. The muzzle is long, but… »
The German Wirehaired Pointer has a coarse, wiry, weather-resistant coat with a thick undercoat. The coat is basically water-repellent and protects it… »
An element with atomic symbol Ge, atomic number 32, and atomic weight 72.64. »
A country in central Europe, bordering the Baltic Sea and the North Sea, between the Netherlands and Poland, south of Denmark. … »
Bacteria, virus uotros microbios que puede causar infecciones y enfermedades. »
Cuando tose o estornuda, lanza al aire gotas diminutas cargadas de gérmenes. Los resfríos y la gripe suelen diseminarse de esta… »
Free of bacteria, viruses, and other microorganisms that can cause infection and disease. »
Cualquier sustancia o proceso que destruye gérmenes (bacterias, virus u otros microbios que pueden causar infecciones o enfermedades). También se llama… »
Any substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause infection and disease). Also called microbicide. … »
The activated center of a lymphoid follicle in secondary lymphoid tissue where B-Lymphocytes are stimulated by antigens and Helper-Inducer T-Lymphocytes are stimulated… »
A biologic subset of diffuse large B-cell lymphomas with a unique molecular signature or expression profile. It represents approximately 50% of… »
A malignant germ cell tumor arising in the central nervous system. It is characterized by the presence of primitive, large malignant germ… »
Tipo de tumor de célula germinal que se encuentra en la glándula pineal en el cerebro. Entre los síntomas de los germinomas… »
The DNA in germ cells (egg and sperm cells that join to form an embryo). Germline DNA is the source of DNA… »
A gene change in a body's reproductive cell (egg or sperm) that becomes incorporated into the DNA of every cell in the… »
A mutation in the genomic DNA of reproductive cells (egg or sperm) that is retained during meiosis, mitosis, and cell differentiation. Ultimately,… »
When you cough or sneeze, you send tiny germ-filled droplets into the air. Colds and flu usually spread that way. You… »
A registered nurse with specialization and higher level of training in treating the elderly population. This includes the management of acute and… »
Clinical specialists in gerontological nursing are experts in providing, directing, and influencing the care of older adults and their families and significant… »
Nursing practices for older age individuals »
A fibrous envelope of tissue that surrounds the kidney. Also called Gerota's fascia and renal fascia. »
A fibrous envelope of tissue that surrounds the kidney. Also called Gerota's capsule and renal fascia. »
A diet plan that has been claimed to be a treatment for cancer, migraine, tuberculosis, and other diseases. It is a vegetarian… »
A very rare and fatal disorder of spongiform encephalopathy usually caused by mutations of the prion protein (PRNP) gene. It is characterized… »
A scale used as an instrument to assess a child's motor and language development, as well as personal-social and adaptive behaviors. … »
The period of fetal development in the uterus from the start of conception until its birth. »
The estimated age of a fetus, this can be determined by the first day of the last menstrual cycle of the mother… »
A rare, highly malignant, epithelial tumor that develops from a hydatidiform mole (50%), following abortion (25%), or during normal pregnancy (22%). Histologically,… »
Carbohydrate intolerance first diagnosed during pregnancy. »
Carbohydrate intolerance first diagnosed during pregnancy. Diagnosis from abnormal oral glucose tolerance test (OGTT) but normal glucose levels when fasting and two… »
Carbohydrate intolerance first diagnosed during pregnancy. Diagnosis from abnormal oral glucose tolerance test (OGTT) and abnormal fasting or post-prandial glucose levels. Euglycemia… »
A rare malignant trophoblastic tumor that arises from the ovary as a result of ectopic ovarian pregnancy. There is no germ… »
The sac that envelops the embryo. It is composed of extraembryonic membranes. »
A rare condition in which abnormal cells grow inside the uterus from tissue that forms after conception (the joining of sperm and… »
A rare condition in which abnormal cells grow inside the uterus from tissue that forms after conception (the joining of sperm and… »
A clinical finding about one or more characteristics of gestational trophoblastic tumor, following the rules of the TNM AJCC v7 classification system… »
A clinical finding about one or more characteristics of gestational trophoblastic tumor, following the rules of the TNM AJCC v7 classification… »
A pathologic finding about one or more characteristics of gestational trophoblastic tumor, following the rules of the TNM AJCC v7 classification system… »
A pathologic finding about one or more characteristics of gestational trophoblastic tumor, following the rules of the TNM AJCC v7 classification system… »
A pathologic finding about one or more characteristics of gestational trophoblastic tumor, following the rules of the TNM AJCC v7 classification… »
A finding about one or more characteristics of gestational trophoblastic tumor, following the rules of the TNM AJCC v7 classification system. … »
A standard determination of fetal age; it is the number of weeks since the first day of the last menstrual period of… »
A question about whether an individual gets frustrated because they can't do things that they used to be able to do. … »
A question about whether an individual gets headaches. »
A question about whether an individual gets or has gotten a ringing or buzzing in their ears. »
A question about whether an individual tires or has tired easily. »
A question about whether an individual is able to get to places beyond walking distance. »
An IgG2 humanized monoclonal antibody against the pro-inflammatory cytokine interleukin 1 beta (IL-1b) with anti-inflammatory activity. Gevokizumab binds to IL-1b, thereby preventing… »
This gene may be involved in the regulation of astrocyte morphology and function. »
Human GFAP wild-type allele is located in the vicinity of 17q21and is approximately 10 kb in length. This allele, which encodes glial… »
This gene plays a role in transcriptional regulation and erythroid cell growth. Translocations in the gene are associated with chronic myeloid… »
Human GFI1B wild-type allele is located in the vicinity of 9q34.13 and is approximately 46 kb in length. This allele, which encodes… »
A test that checks for occult (hidden) blood in the stool. Small samples of stool are placed on special cards coated with… »
NIC96 is a nuclear pore protein identified in yeast. GFP stands for green fluorescent protein. GFP-NIC96 was used for cell localization… »
This gene plays a regulatory role in neuronal survival and differentiation. »
Human GFRA2 wild-type allele is located within 8p21 and is approximately 108 kb in length. This allele, which encodes GDNF family receptor… »
A drug used to treat symptoms of an enlarged prostate gland. It is being studied in the treatment of male hair loss… »
Medicamento usado para tratar síntomas de agrandamiento de la glándula prostática. Está en estudio para el tratamiento de la pérdida de cabello… »
This gene is involved in polyglutamate hydrolysis. »
Human GGH wild-type allele is located in the vicinity of 8q12.3 and is approximately 24 kb in length. This allele, which encodes… »
GH: Develops hypertension, cardiac hypertrophy and vascular disease (Phelan 1968, Simpson and Phelan 1984, Simpson et al, 1994). Genetic hypertension in GH… »
This gene is involved in the control of body growth. It also plays a role in protein synthesis as well as in… »
Human GH1 wild-type allele is located in the vicinity of 17q24.2 and is approximately 2 kb in length. This allele, which encodes… »
A country in western Africa, bordering the Gulf of Guinea, between Cote d'Ivoire and Togo. »
A carcinoma usually arising from the maxilla and less often the mandible. Symptoms include swelling and paresthesia. It is characterized… »
This gene is involved in intercellular growth signal transduction pathways and the regulation of growth hormone. »
Human GHR wild-type allele is located within 5p13-p12 and is approximately 302 kb in length. This allele, which encodes growth hormone receptor… »
The determination of the amount of ghrelin present in a sample. »
A ghrelin peptide analogue with potential anti-cachexia activity. Upon subcutaneous administration, ghrelin peptide analogue binds to and stimulates the G protein-coupled growth… »
This gene is involved in the stimulation of growth hormone release. »
Human GHRH wild-type allele is located in the vicinity of 20q11.2 and is approximately 11 kb in length. This allele, which encodes… »
This gene is involved in regulating growth hormone release and satiety, thirst and anxiety. »
Human GHRL wild-type allele is located within 3p26-p25 and is approximately 7 kb in length. This allele, which encodes appetite-regulating hormone protein,… »
Refers to the stomach and intestines. Also called gastrointestinal. »
Se refiere al estómago y los intestinos. También se llama gastrointestinal. »
A vaccine containing a heat-killed recombinant Saccharomyces cerevisiae yeast transfected with mutated forms of Ras, an oncogene frequently found in solid tumors,… »
An antitumor drug that belongs to the family of drugs called topoisomerase inhibitors. It is a camptothecin analog. »
Medicamento contra tumores que es un tipo de inhibidor de la topoisomerasa. Es un análogo de la camptotecina. »
A rare inherited disorder affecting the neurofilaments. It is caused by mutations in the GAN gene. It is characterized by the presence… »
A large cell-like structure formed by the joining together of two or more cells. The plural is syncytia. »
A malignant epithelial neoplasm composed of giant, pleomorphic cells and spindle cells. »
A rare, slow-growing, locally aggressive soft tissue tumor characterized by the presence of oval to spindle cells forming concentric aggregates around small… »
A morphologic variant of angiofibroma characterized by the presence of multinucleated giant cells, collagenous or myxoid stroma, focal sclerotic areas, and angiectoid… »
Giant cell arteritis is a disorder that causes inflammation of arteries of the scalp, neck, and arms. It narrows the arteries, which… »
A malignant epithelial neoplasm composed of giant, pleomorphic cells. »
A rare type of soft tissue tumor marked by painless nodules in the dermis (the inner layer of the two main layers… »
A sarcoma characterized by the presence of osteoclast-like giant cells and cellular pleomorphism. »
A rare histological variant of glioblastoma (WHO grade IV) with a predominance of bizarre, multinucleated giant cells, an occasionally abundant stromal reticulin… »
A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant… »
An often fatal inflammatory disorder that affects the myocardium. Morphologically, it is characterized by the presence of an inflammatory infiltrate in the… »
A sarcoma characterized by the presence of large, anaplastic malignant cells. »
A rare tumor that usually forms in bone, but may also form in cartilage, muscle, fat, blood vessels, or other supportive tissue… »
A benign or malignant bone tumor, usually arising in the end of long bones or the vertebrae. The tumor is composed of… »
A painless, well circumscribed tumor arising in soft tissue, usually of the upper and lower extremities. Morphologically, it is characterized by a… »
A tumor usually arising in the synovium of joints, bursa or tendon sheath. It is characterized by the presence of mononuclear cells,… »
A large penile lesion with indolent clinical course, composed of well-differentiated squamous cells. -- 2003 »
A rare melanocytic lesion occurring at birth, comprising at least 5% of the body surface area. It usually presents as a dark… »
A fibroadenoma characterized by a very large size. This term has also been used as a synonym for juvenile fibroadenoma by some… »
A benign, elongated intraluminal polypoid neoplasm of the esophagus. It is characterized by the presence of adipose tissue lobules separated by… »
A cavernous hemangioma characterized by the presence of hylanized vascular channels and is often associated with the presence of calcifications, fibrosis, and… »
A condition marked by inflammation and ulcers (breaks on the skin or on the surface of an organ) of the mucosa (inner… »
A rare disorder in which benign (not cancer) growths form in lymph node tissue. There are two main ways that giant lymph… »
The determination of the amount of giant neutrophils present in a sample. »
The determination of the number of giant platelets present in a sample. »
The Giant Schnauzer is a large, compact dog with bushy eyebrows, whiskers and a beard. It has a harsh, wiry outer coat… »
A genus of parasitic protozoa that is the cause of giardiasis. »
Giardiasis is an illness caused by a parasite called Giardia intestinalis. It lives in soil, food, and water. It may also be… »
A prefix used in binary numeral system for denoting a quantity of two raised to the power of 30, which is equal… »
A dependency in southwestern Europe, on the southern coast of Spain, bordering the Strait of Gibraltar. »
A microscopy staining method that utilizes Giemsa, a mixture of ethylene blue and eosin, which forms purplish-black crystals when dried. This stain… »
A prefix indicating a quantity of one billion, 10E9. »
A unit of radioactivity equal to 10E9 nuclear disintegrations or other nuclear transformations per second, or to 10E9 becquerels. »
A unit of specific radioactivity (massic activity) equal to activity of one gigabecquerel of the sample with total mass of one… »
A unit of specific radioactivity (massic activity) equal to activity of one gigabecquerel of the sample with total mass of one… »
A metric unit of volumetric radioactivity concentration defined as a concentration of a radionuclide with an activity equal to one billion becquerels… »
A unit of specific radioactivity (massic activity) equal to activity of one gigabecquerel of the sample with total mass of one… »
A rare, benign, slow growing, multifocal, and expansile lesion of the jaws. Both familiar and sporadic cases have been reported. It is… »
A condition in which the whole body or any of its parts grow much larger than normal. »
Afección por la cual todo el cuerpo o cualquiera de sus partes crece mucho más de lo normal. »
Gigaxonin (597 aa, ~68 kDa) is encoded by the human GAN gene. This protein plays a role in the modulation of both… »
A CGS unit of magnetomotive force equal to 0.7958 ampere-turns in the SI. »
An autosomal recessive inherited disorder characterized by unconjugated hyperbilirubinemia, resulting in harmless intermittent jaundice. »
A respiratory organ found in aquatic animals that allows for the exchange of dissolved oxygen from water into the blood stream. … »
A drug used to treat non-small cell lung cancer that has spread to other parts of the body. It is used in… »
Medicamento para tratar el cáncer de pulmón de células no pequeñas que se diseminó a otras partes del cuerpo. Se usa en… »
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called topoisomerase inhibitors. Also… »
Sustancia en estudio para el tratamiento de cáncer. Es un tipo de inhibidor de la topoisomerasa. También se llama ST1481. »
A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase… »
Relacionado con el sistema reproductivo femenino (comprende el cuello uterino, el endometrio, las trompas de Falopio, los ovarios, el útero y la… »
Médico que se especializa en el tratamiento de enfermedades de los órganos reproductivos femeninos. »
Crecimiento anormal del tejido glandular en las mamas del hombre. La ginecomastia en los lactantes y los niños podría ser a causa… »
An herb with a root that has been used in cooking, and by some cultures to treat nausea, vomiting, and certain other… »
An extract of the rhizome of the perennial plant Zingiber officinale with potential antineoplastic activity. Ginger extract contains a number of different… »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
The essential oil of Zingiber officinale. Ginger oil has been used for digestive health. »
The tissue of the upper and lower jaws that surrounds the base of the teeth. Also called gums. »
El tejido de la mandíbula superior o inferior que rodea la base de los dientes. También se llama encías. »
Of or relating to the gums. »
A benign neoplasm arising from the fibrous soft tissues of the gingiva. It is characterized by the presence of spindle-shaped fibroblasts, and… »
A carcinoma of the oral cavity that arises from the upper or lower gingiva. »
A non-neoplastic nodular lesion that arises from the gingiva. It is composed of epithelial cells lining connective tissue stroma. »
A hemangioma arising from the gums. »
The crest of the gingiva surrounding a tooth. »
A benign or malignant neoplasm that affects the upper or lower gingiva. »
Painful sensation in the gingival region. »
An abnormal deepening of a gingival sulcus not associated with destruction of the supporting periodontal tissue. »
A non-neoplastic nodular lesion that arises from the gingiva. »
A loss of gum tissue resulting in an exposure of the roots of the teeth. »
A resective periodontal surgical procedure that removes gingival tissue. »
A disorder involving inflammation of the gums; may affect surrounding and supporting structures of the teeth. »
A tree native to China. Substances taken from the leaves and seeds have been used in some cultures to treat certain medical… »
Árbol originario de la China. En algunas culturas, se han usado sustancias extraídas de las hojas y las semillas para el tratamiento… »
A tree native to China. Substances taken from the leaves and seeds have been used in some cultures to treat certain medical… »
Árbol originario de la China. En algunas culturas, se han usado sustancias extraídas de las hojas y las semillas para el tratamiento… »
Hierba con una raíz que se ha usado en algunas culturas para el tratamiento de ciertos problemas médicos. Puede tener efectos contra… »
An herb with a root that has been used in some cultures to treat certain medical problems. It may have anticancer… »
The aromatic root of perennial herbs of Panax ginseng. »
A capsule containing the steroidal saponin ginsenoside Rg3 isolated from the root of Panax ginseng, with potential cancer preventive and anti-angiogenic… »
This gene plays a role in glucose homeostasis. »
Human GIP wild-type allele is located within 17q21.3-q22 and is approximately 10 kb in length. This allele, which encodes gastric inhibitory polypeptide,… »
This gene is involved in G protein-coupled receptor signal transduction and may play a role in glucocorticoid and anabolic metabolism. »
Human GIPR wild-type allele is located in the vicinity of 19q13.3 and is approximately 14 kb in length. This allele, which encodes… »
A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, monoclonal… »
A girl or woman who is the lover of a boy or man. »
A compound isolated from the marine sponge Pseudaxinyssa cantharella exhibiting anti-tumor activity. Studies indicate girodazole acts during the elongation/termination steps of… »
Greenland Ice Sheet Project 2, the second phase of an effort by a group of scientists to produce long records of climate… »
A type of tumor that usually begins in cells in the wall of the gastrointestinal tract. It can be benign or… »
A statistical approach for identifying genomic regions of aberration that are more likely to drive cancer pathogenesis. The method identifies those regions… »
This gene plays a role in signal transduction and cytoskeletal remodeling. »
Human GIT1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 16 kb in length. This allele, which encodes… »
This gene is involved in signal transduction and regulation of receptor signaling. »
Human GIT2 wild-type allele is located in the vicinity of 12q24.1 and is approximately 66 kb in length. This allele, which encodes… »
An inherited disorder caused by mutations in the SLC12A3 gene. It is characterized by deficient reabsorption of electrolytes in the distal convoluted… »
An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. GITRL RNA-transfected autologous DC vaccine is prepared by transfecting DCs with… »
Transfer possession of something to some person or group. »
An orally bioavailable hydroxymate inhibitor of histone deacetylase (HDAC) with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. Givinostat inhibits class I and class… »
The thick-walld muscular pouch, part of the digestive system of birds, insects and invertebrates, which is responsible for digestion. It is located… »
This gene plays a role in the modulation of glycerol metabolism. »
Human GK wild-type allele is located in the vicinity of Xp21.3 and is approximately 77 kb in length. This allele, which encodes… »
An epipodophyllotoxin analogue possessing antineoplastic properties. GL331 binds to and inhibits topoisomerase II, resulting in the accumulation of single- or double-strand… »
River of ice that under pressure can deform and flow plastically. »
An organ that makes one or more substances, such as hormones, digestive juices, sweat, tears, saliva, or milk. Endocrine glands release the… »
An architectural morphologic finding indicating branching of glands as a result of a pathologic process. »
Architectural distortion of the tissue structure of a gland. »
A morphologic finding indicating the partial or complete loss of a gland structure. »
The small accessory lacrimal glands on the upper and lower eyelids that secrete tears. There are approximately 42 glands on the upper… »
Tube-like gland found in the lining of the colon and rectum. Glands of Lieberkuhn renew the lining of the intestine and make… »
Any of the glands located at the wall of the urethra of male mammals that produce and secrete mucus, a major component… »
A gland in the margins of the eyelids that opens into the follicles of the eyelashes and produces secretions that lubricate the… »
A gland producing tears in a third eyelid in the corner of each eye, as seen in animals. »
The larger accessory lacrimal glands on the upper and lower eyelids that secrete tears. There are approximately 2-5 glands on the upper… »
La cabeza redondeada, con aspecto de glándula del pene. »
A contagious disease of horses that can be transmitted to humans. It is caused by Burkholderia mallei and characterized by ulceration of… »
Órgano que produce una o más sustancias, como las hormonas, los jugos digestivos, el sudor, las lágrimas, la saliva o la… »
Tipo de glándula que se encuentra en la piel, la mama, el párpado y el oido.La glándulas apocrinas de las mamas segregan… »
Glándula con forma parecida a un tubo que se encuentra en el revestimiento del colon y el recto. Las glándulas de Lieberkuhn… »
Tipo de glándula sudorípara simple que se encuentra en casi todas las áreas de la piel. Estas glándulas producen un sudor que… »
Glándula que segrega lágrimas. Las glándulas lagrimales se encuentran en la parte superior y exterior de cada cuenca del ojo. »
Masa redondeada de tejido linfático rodeada por una cápsula de tejido conjuntivo. Las glándulas linfáticas filtran la linfa (líquido linfático), y almacenan… »
Órgano glandular ubicado en el pecho. La glándula mamaria está formada por tejido conjuntivo, grasa y tejido que contienen las glándulas que… »
Una de las cuatro pequeñas glándulas en forma de arveja que se encuentran sobre la superficie de la tiroidea. La hormona paratiroidea… »
Órgano pequeño de la corteza o córtex que produce melatonina. También se llama cuerpo pineal y órgano pineal. »
Glándula de la boca que produce saliva. »
Glándula pequeña que produce hormonas esteroideas, epinefrina y norepinefrina. Estas hormonas ayudan a controlar los latidos del corazón, la presión arterial y… »
Glándula localizada debajo de la laringe que produce la hormona tiroidea y calcitonina. La glándula tiroides ayuda a regular el crecimiento y… »
An epithelial cell which may release secretions to a free epithelial surface (exocrine) or to the circulatory system (endocrine). »
A type of cell that makes mucus and is found in tissue that lines the inner part of the cervix. Abnormal glandular… »
Dilation of the glandular unit with compression of the epithelium. »
A microscopic finding indicating the presence of cells with glandular differentiation in a tumor sample. »
Proliferation of the glandular epithelial cells. »
A variant of malignant peripheral nerve sheath tumor characterized by the presence of glandular epithelium. »
Forms glandular structures with abundant secretory products in lumen. »
A morphologic finding indicating the alteration of the squamous or transitional epithelial cells to glandular cells. »
Multifocal neoplastic proliferations of the glandular epithelium displaying a papillary pattern. »
The part of the stomach that is lined with glandular mucosa and receives the food from the esophagus. The mucosa contains gastric… »
The external structure of the clitoris covered by the clitoral hood. »
The rounded, gland-like head of the penis. »
A rare, autosomal recessive inherited and less frequently acquired platelet disorder. It is characterized by deficient or dysfunctional glycoprotein IIb/IIIa complex. It… »
A brittle transparent solid with irregular atomic structure. »
A glass vessel with a narrow neck designed to accept a specific closure. »
A device for the administration of parenteral drug products that consists of a rigid glass barrel fitted with septum with a plunger… »
A glass container designed for use with parenteral drug products. »
Frames with lenses worn in front of the eye for vision correction, eye protection, or protection from UV rays. »
The Glasswashing and Sterilization Shared Resource perform the preparation of clean sterile regular and special needs glassware for Cancer Center laboratories. … »
A malignant epithelial neoplasm composed of atypical cells with glassy cytoplasm. »
A polycyclic lactone quassinoid phytochemical isolated from the seeds of Hannoa undulata and other plant species with potential antineoplastic activity. This… »
A condition in which there is a build-up of fluid in the eye, which presses on the retina and the optic… »
Afección por la cual se produce una acumulación de líquido en el ojo que presiona sobre la retina y el nervio… »
This gene plays a role in ganglioside metabolism. »
Human GLB1 wild-type allele is located in the vicinity of 3p22.3 and is approximately 101 kb in length. This allele, which encodes… »
A grading system for prostatic carcinoma based on the microscopic glandular architectural patterns of the malignant epithelial cells. Nuclear atypia is not… »
A pattern of prostate carcinoma characterized by the presence of a well circumscribed nodule of separate glands which are closely packed. There… »
A pattern of prostate carcinoma characterized by the presence of glands that are more loosely arranged and less uniform compared to Gleason… »
A pattern of prostate carcinoma characterized by the presence of glands that are infiltrative and vary in size and shape. The epithelial… »
A pattern of prostate carcinoma characterized by the presence of fused, cribriform, or poorly defined glands. There is partial loss of normal… »
A pattern of prostate carcinoma characterized by almost complete loss of epithelial polarity and luminal differentiation. »
A system of grading prostate cancer tissue based on how it looks under a microscope. Gleason scores range from 2 to 10… »
The score derived from universally embraced prostate cancer grading system developed by Dr. Donald F. Gleason in 1977. The system provides a… »
A drug used to treat different types of leukemia and other cancers of the blood, gastrointestinal stromal tumors, skin tumors called dermatofibrosarcoma… »
Medicamento que se usa para tratar diferentes tipos de leucemia y otros cánceres de la sangre, tumores del estroma gastrointestinal, tumores de… »
A human monoclonal antibody against transmembrane glycoprotein non-metastatic melanoma protein B (GPNMB). Glembatumumab binds to GPNMB on cancer cells, but alone does… »
An antibody-drug conjugate, consisting of the fully human monoclonal antibody CR011 directed against glycoprotein NMB (GPNMB) and conjugated via a cathepsin B-sensitive… »
The Glen of Imaal Terrier is a sturdy dog that resembles the Welsh Corgi - a short legged dog that is low… »
The trough in the head of the scapula that receives the head of the humerus to form the shoulder joint. »
A drug used to treat brain tumors that have already been treated with surgery or radiation therapy. It is also used to… »
GLI Family Genes encode DNA-binding GLI Family Proteins containing zinc finger repeats and involved in pattern formation. »
A group of DNA-binding proteins that contain zinc finger repeats and involves pattern formation process. »
This gene plays a regulatory role in transcription and embryonic development. »
Human GLI1 wild-type allele is located within 12q13.2-q13.3 and is approximately 12 kb in length. This allele, which encodes zinc finger protein… »
This gene is involved in transcriptional regulation and plays a role in sonic hedgehog signal transduction. »
Human GLI2 wild-type allele is located in the vicinity of 2q14 and is approximately 200 kb in length. This allele, which encodes… »
This gene plays a regulatory role in limb development and is involved in sonic hedgehog signal transduction. »
Human GLI3 wild-type allele is located in the vicinity of 7p13 and is approximately 272 kb in length. This allele, which encodes… »
A biodegradable wafer that is used to deliver the anticancer drug carmustine directly into a brain tumor site after the tumor has… »
Any of the cells that hold nerve cells in place and help them work the way they should. The types of glial… »
Glial Cell-Line Derived Neurotrophic Factor contains seven conserved cysteine residues spaced similar to the TGF-beta superfamily. GDNF is processed to a… »
Glial Cell Proliferation involves multiplication or reproduction through cell division of various types of glial cells, neural supportive cells in the central… »
Glial fibrillary acidic protein (432 aa, ~50 kDa) is encoded by the human GFAP gene. This protein may be involved in both… »
A general term for tumors of the central nervous system, including astrocytomas, ependymal tumors, glioblastoma multiforme, and primitive neuroectodermal tumors. »
A sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, gliamilide is able to lower blood glucose levels by increasing the release of insulin… »
A sulfonamide derivative with antiulcerative activity. »
An sulfonylurea with structural variation to glibenclamide, in which 2-methoxy-5-chlorobenzyl is replaced by a cyclic acyl group, with hypoglycemic activity. Glicaramide also… »
A sulfonamide derivative with antihyperglycemic activity. Glicetanile is both rapidly metabolized and eliminated via urine and faeces after oral and i.v. administration,… »
The sodium salt form of glicetanile, a sulfonamide derivative with antihyperglycemic activity. Glicetanile is both rapidly metabolized and eliminated via urine and… »
Planta de origen asiático que produce granos que se usan en muchos productos alimenticios. Glycine max contiene isoflavonas (sustancias similares al estrógeno)… »
A short-acting, relatively high-potency, second-generation sulfonylurea compound with hypoglycemic activity. Gliclazide also increases peripheral insulin sensitivity. This agent is metabolized by… »
Proceso en el cual las células en las reacciones enzimáticas que no necesitan oxígeno descomponen parcialmente la glucosa (azúcar). La glicólisis es… »
A sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, glicondamide is able to lower blood glucose levels by increasing the release of insulin… »
Cadena corta de aminoácidos (los elementos fundamentales de las proteínas) con moléculas de azúcar adheridas. Se ha estudiado la capacidad de algunos… »
Proteína que bombea sustancias fuera de las células. Las células cancerosas que tienen demasiada glicoproteína p podrían no ser destruidas… »
Forma del factor de crecimiento y desarrollo megacariocítico (MGDF, por sus siglas en inglés) que se produce en el laboratorio. El MGDF… »
An inactive ingredient of the solid pharmaceutical dosage form added to cement the active and inert components of tablets together to maintain… »
A second-generation, sulfonamide urea derivative with antihyperglycemic activity. Glidazamide's hypoglycemic effect is inferior to that of glicaramide. »
A fluoro-containing sulfadiazine derivative with hypoglycemic activity. Although not technically a sulfonylurea compound, gliflumide targets the sulfonylurea receptor and exerts a similar… »
A long-acting, third-generation sulfonylurea with hypoglycemic activity. Compared to other generations of sulfonylurea compounds, glimepiride is very potent and has a longer… »
A fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has… »
Tipo de tumor cerebral de crecimiento rápido del sistema nervioso central que se forma a partir del tejido glial (de sostén) del… »
Classification of glioblastoma into molecular subtypes as defined by gene expression profiling. »
A cancer vaccine composed of a combination of autologous glioblastoma (GBM) tumor cells, allogeneic GBM tumor cells, generated from three different GBM… »
A fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has… »
Tipo de tumor cerebral de crecimiento rápido del sistema nervioso central que se forma a partir del tejido glial (de sostén) del… »
A cancer vaccine comprised of 11 peptides associated with glioblastoma multiforme (GBM), with potential immunomodulating and antineoplastic activities. Vaccination with glioblastoma multiforme… »
Glioblastoma multiforme (GBM) formation is either de novo (primary GBMs) or due to the progression of a lower grade glioma to a… »
An astrocytic tumor affecting young people. Morphologically, it is characterized by the presence of collagenous tissue surrounding neoplastic astrocytes. In… »
A cancer of the brain that begins in glial cells (cells that surround and support nerve cells). »
Cáncer cerebral que se inicia en las células neurogliocíticas (células que rodean y sostienen las células nerviosas). »
Tumor poco frecuente, de crecimiento lento que, por lo general, se forma en el nervio óptico, el quiasma óptico o el tracto… »
Tumor poco frecuente, de crecimiento lento que, por lo general, se forma en el nervio óptico, el quiasma óptico o el tracto… »
Tumor ubicado en la parte del cerebro que se conecta con la médula espinal (el tronco encefálico). Puede crecer rápida o lentamente,… »
A group of of six collaborating laboratories at medical centers located throughout the U.S. working to identify new molecular alterations that may… »
Tumor de cerebro que se forma con más de un tipo de célula del cerebro, por lo general, astrocitos y oligodendrocitos. … »
Tipo de tumor del sistema nervioso central que se forma con tejido glial (de sostén) del cerebro y la médula espinal. El… »
Glioma Tumor Suppressor Candidate Region Gene 1 Protein is encoded by the human GLTSCR1 gene. This protein is expressed at moderate levels… »
Glioma tumor suppressor candidate region gene 2 protein (478 aa, ~54 kDa) is encoded by the human GLTSCR2 gene. This protein may… »
A cancer vaccine comprised of autologous dendritic cells pulsed with synthetic glioma-associated antigen (GAA) peptides with potential antineoplastic activity. Upon administration, this… »
A diffuse glial tumor which infiltrates the brain extensively, involving more than two lobes. It is frequently bilateral and often extends to… »
A rare, WHO grade II or III infiltrating astrocytoma characterized by the presence of sharply demarcated foci, composed of a neuropil-like… »
A type of glioma (cancer of the brain that comes from glial, or supportive, cells). »
Tipo de glioma (cáncer del cerebro que proviene de células gliales o de sostén). »
Reactive astrocytic proliferation associated with fibrous tissue formation, secondary to damage (trauma or ischemia) to the central nervous system. »
A second-generation sulfonamide derivative with antihyperglycemic activity. Like other sulfonylureas, glipalamide exerts extra-pancreatic activity, such as increased binding of insulin to insulin… »
A short-acting, second-generation sulfonylurea with hypoglycemic activity. Glipizide is rapidly absorbed, has a very quick onset of action and a short… »
This gene plays a role in the immune response. »
Human GLIPR2 wild-type allele is located within 9p13-p12 and is approximately 27 kb in length. This allele, which encodes golgi-associated plant pathogenesis-related… »
A potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater binding affinity to SUR1 and increased potency compared… »
This gene is involved in transcriptional regulation and signaling pathway modulation. »
Human GLIS2 wild-type allele is located in the vicinity of 16p13.3 and is approximately 25 kb in length. This allele, which encodes… »
A second-generation sulfonylurea with antihyperglycemic activity. Like other larger sulfonylurea compounds, glisamuride appears to exert greater binding affinity for peroxisome proliferator-activated receptor… »
A cyclopentyl containing, second-generation sulfonylurea and structurally similar to glibenclamide with hypoglycemic activity. Glisentide, also known as glypentide, appears to improve total… »
A second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, glisindamide exerts greater binding affinity to sulfonylurea receptor type 1 (SUR1) than… »
A second-generation sulfonylurea with antihyperglycemic activity. Glisolamide is comparable to glyburide and gliquidone in controlling blood glucose levels. »
A second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, glisoxepide exerts greater binding affinity than the first-generation compounds. Glisoxepide shows peroxisome… »
Any agent within the glitazar class that are dual or pan-acting peroxisome proliferator-activated receptor (PPAR) agonists with insulin sensitizing and lipid lowering… »
This gene plays a role in vascular development. »
Human GLMN wild-type allele is located in the vicinity of 1p22.1 and is approximately 53 kb in length. This allele, which encodes… »
Covering or affecting the whole of a system. »
Refers to large-scale environmental and cultural changes on Earth. »
An increase in global UV with the diminishing of the ozone layer »
The submission of a global unique device identification record. »
An increase in temperature that occurs globally such as the interglacial warming period the earth experienced after the last Ice Age, or… »
A genus of facultatively anaerobic, Gram variable, cocci shaped bacterium assigned to the phylum Firmicutes and the family Aerococcaceae. »
A species of facultatively anaerobic, gram positive cocci shaped bacteria assigned to the Phylum Firmicutes. This species is catalase negative and does… »
A species of facultatively anaerobic Gram variable cocci shaped bacteria assigned to the phylum Firmicutes. This species is catalase negative, produces hydrogen… »
A multivalent vaccine comprised of the epitope antigens of Globo H hexasaccharide 1 (Globo H), GM2 ganglioside, Lewis-Y, MUC1-32-mer, TF(c), and Tn(c)… »
A multivalent vaccine comprised of Globo H (Globo H Hexasaccharide 1), GM2, Lewis-y, MUC1-32-mer, TF(c), and Tn(c) antigens conjugated with Keyhole Limpet… »
A carbohydrate-based immunostimulant comprised of the Globo H hexasaccharide 1 (Globo H) epitope linked to the immunostimulant carrier protein keyhole limpet hemocyanin… »
A heptavalent vaccine consisting of the tumor-associated carbohydrate antigens globohexaosylceramide (globo-H), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) conjugated with keyhole limpet… »
A heptavalent vaccine comprised of Globo-H (Globo H Hexasaccharide 1), GM2, Lewis-y, MUC1-32(aa), sTn(c), TF(c), and Tn(c) antigens conjugated with Keyhole Limpet… »
A protein region consisting of a hydrophilic surface and a hydrophobic core. »
A solid composed of sucrose, lactose or other polysaccharides formed into small globular pellets impregnated with active and/or inert ingredient(s). »
An unit of small globular masses of various sizes. Medications are compounded with globular shaped sucrose, lactose, or other polysaccharides and dried… »
The determination of the amount of globulin protein present in a sample. »
Suero de la sangre que contiene anticuerpos que se unen con las células T humanas. La globulina antilinfocítica se administra al paciente… »
Suero de la sangre que contiene anticuerpos que se unen con las células T humanas. La globulina antitimocítica se administra al paciente… »
Tipo de célula sanguínea que se produce en la médula ósea y que se encuentra en la sangre y los tejidos… »
Tipo de célula sanguínea que se produce en la médula ósea y que se encuentra en la sangre. Los glóbulos rojos contienen… »
The representation of the phylogenetically oldest part of the corpus striatum called the paleostriatum. It forms the smaller, more medial part of… »
A morphologic variant of the glomus tumor characterized by the presence of dilated veins, surrounded by small clusters of glomus cells. Glomangiomas… »
A benign multifocal proliferation of glomus cells forming clusters around dilated vascular spaces. »
A morphologic variant of the glomus tumor with architectural features similar to solid glomus tumor. It is characterized by the presence… »
A sheet of amorphous extracellular material upon which the basal surfaces of epithelial cells rest and is the covering surface of a… »
A finding indicating the presence of protrusions or extensions in the basement membrane of the glomeruli. »
A morphologic finding indicating the presence of wrinkles in the basement membrane of the glomeruli. »
A kidney function test that measures the fluid volume that is filtered from the kidney glomeruli to the Bowman's capsule per unit… »
The determination of the glomerular filtration rate whose result is adjusted for body surface area. »
A laboratory test result which indicates a decreased glomerular filtration rate. »
A measurement of the glomerular filtration rate (GFR) based on the clearance of beta-2 microglobulin after adjusting it for the body surface… »
A measurement of the glomerular filtration rate (GFR) based on the clearance of beta-trace protein after adjusting it for the body surface… »
The determination of the glomerular filtration rate by measurement of creatinine clearance and whose result is adjusted for body surface area. … »
The determination of the glomerular filtration rate by measurement of cystatin c clearance and whose result is adjusted for body surface… »
A morphologic finding indicating enlargement of the glomeruli in a kidney specimen. »
Cells found within the glomerular lobules of mammalian kidney, where they serve as structural supports, may regulate blood flow, are phagocytic and… »
Racimo pequeño y redondo de vasos sanguíneos en el interior de los riñones. Filtra la sangre para reabsorber materiales útiles y extrae… »
A morphologic finding that refers to microvascular proliferation that resembles glomeruloid structures. It is seen in gliomas. »
A renal disorder characterized by damage in the glomeruli. It may be acute or chronic, focal or diffuse, and it may lead… »
A cluster of convoluted capillaries beginning at each nephric tubule in the kidney and held together by connective tissue. »
Encoded by human GLMN Gene, two alternative isoforms of ubiquitous monomeric Glomulin interact with immunophilins FKBP59, FKBPP52, and FKBP12 that bind the… »
A rare benign or malignant mesenchymal neoplasm arising from cells that resemble the modified smooth muscle cells of the glomus body. The… »
A glomus tumor arising from the skin. It usually presents as a small red-blue nodule and it often associated with pain… »
A glomus tumor that shows atypical characteristics and has borderline malignant potential. »
Extirpación quirúrgica total o parcial de la lengua. »
An alphabetical list of technical terms in some specialized field of knowledge; usually published as an appendix to a text on that… »
Surgical removal of all or part of the tongue. »
Inflammation of the tongue. »
The ninth cranial nerve. It originates in the brainstem and passes through the jugular foramen. It has motor and sensory functions that… »
A non-neoplastic or neoplastic disorder affecting the glossopharyngeal nerve (ninth cranial nerve). »
A groove between the base of the tongue and the palatine tonsil. »
La sección media de la laringe; zona donde se encuentran las cuerdas vocales. »
A clinical finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v7 classification system as… »
A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM classification system as they pertain… »
A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v7 classification system as… »
A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v6 classification system as… »
A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v7 classification system as… »
A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM classification system as they pertain… »
A pathologic finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v6 classification system. … »
A finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v6 classification system. »
A finding about one or more characteristics of glottic cancer, following the rules of the TNM AJCC v7 classification system. »
The middle part of the larynx; the area where the vocal cords are located. »
A carcinoma of the larynx that arises from the glottic area. »
A benign or malignant neoplasm that affects the glottic area of the larynx. »
A squamous cell carcinoma of the larynx that arises from the glottic area. It may remain localized for a long period… »
An exophytic, slow growing, well differentiated and non-metastasizing squamous cell carcinoma with pushing margins that arises from the glottic area of the… »
A mass spectrometry technique in which a solid sample is atomized and ionized by sputtering in low-pressure direct-current plasma prior to the… »
Any of the analogues of the endogenous gastrointestinal hormone glucagon-like peptide-1 (GLP-1) with antihyperglycemic activity. GLP-1 mimetics mimic the activity of GLP-1… »
This gene is involved in the maintenance of cellular homeostasis. »
Human GLRX3 wild-type allele is located in the vicinity of 10q26 and is approximately 48 kb in length. This allele, which encodes… »
This gene is involved in the regulation of glutamine catabolism. »
Human GLS2 wild-type allele is located within 12q13 and is approximately 17 kb in length. This allele, which encodes glutaminase liver isoform,… »
This gene is involved in sphingolipid transport. »
Human GLTPD1 wild-type allele is located in the vicinity of 1p36.33 and is approximately 4 kb in length. This allele, which encodes… »
This gene may play a role in the negative regulation of cell growth. »
Human GLTSCR1 wild-type allele is located in the vicinity of 19q13.3 and is approximately 24 kb in length. This allele, which encodes… »
This gene plays a role in the regulation of protein phosphorylation and turnover. »
Human GLTSCR2 wild-type allele is located in the vicinity of 19q13.3 and is approximately 12 kb in length. This allele, which encodes… »
A hormone produced by the pancreas that increases the level of glucose (sugar) in the blood. »
Hormona producida por el páncreas que aumenta la concentración de glucosa (azúcar) en la sangre. »
The determination of the amount of glucagon hormone present in a sample. »
A process that involves the non-covalent binding of glucogon to the glucogon receptor. This interaction plays a role in the initiation of… »
The determination of the amount of glucagon-like peptide-1 present in a sample. »
A rare pancreatic tumor that produces a hormone called glucagon. Glucagonomas can produce symptoms similar to diabetes. »
Tumor pancreático poco común, que produce una hormona que se llama glucagón. Los glucagonomas pueden producir síntomas similares a la diabetes. … »
Molécula grande de carbohidrato. Contiene muchas moléculas pequeñas de azúcar que están vinculadas químicamente entre sí. También se llama polisacárido. »
Medicamento que se usa para tratar concentraciones tóxicas de metotrexato (un medicamento contra el cáncer) en la sangre de pacientes con problemas… »
A drug used to treat toxic levels of methotrexate (an anticancer drug) in the blood of patients with kidney problems. It is… »
Glucosa (tipo de azúcar) que se encuentra en la sangre. También se llama azúcar sanguíneo. »
The Glucksberg scale is a severity index for grading acute graft-versus-host disease (GVHD) after allogeneic marrow transplantation. This index is based on… »
A compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They… »
Glucocorticoid receptor (777 aa, ~86 kDa) is encoded by the human NR3C1 gene. This protein plays a role in both chromatin remodeling… »
Glucocorticoid receptor DNA-binding factor 1 (1513 aa, ~172 kDa) is encoded by the human GRLF1 gene. This protein plays a role in… »
Glucocorticoid Secretion Inhibition consists of interference with, or restraint of, activities involved in release into the bloodstream by the adrenal cortex of… »
Glucocorticoid Secretion Induction consists of initiation of activities involved in release into the bloodstream by the adrenal cortex of a class of… »
Compuesto que pertenece al tipo de los llamados corticosteroides (esteroides). Los glucocorticoides afectan el metabolismo y tienen efectos antiinflamatorios e inmunodepresores. Pueden… »
El mineral calcio combinado con una forma de glucosa de azúcar. Se usa para prevenir y tratar la osteoporosis (disminución de la… »
Forma del mineral hierro que se usa para tratar la anemia que resulta de tener concentraciones bajas de hierro en la… »
The process of making glucose (sugar) from its own breakdown products or from the breakdown products of lipids (fats) or proteins. Gluconeogenesis… »
El proceso de elaboración de glucosa (azúcar) a partir de sus propios productos de descomposición o de los productos de descomposición de… »
Gluconeogenesis Induction involves initiation of the biosynthesis of glucose from 3-carbon non-carbohydrate precursors, including amino acids (from protein breakdown during starvation). … »
Gluconeogenesis Inhibition involves interference with, or restraint of, the biosynthesis of glucose from 3-carbon non-carbohydrate precursors, including amino acids. »
The biosynthesis of new glucose as opposed to that generated by the metabolism of glycogen. Gluconeogenesis occurs mainly in the liver or… »
The carboxylic acid formed by the oxidation of the first carbon of glucose with antiseptic and chelating properties. Gluconic acid, found abundantly… »
A naturally occurring polyhydroxy acid (PHA) with metal chelating, moisturizing and antioxidant activity. Gluconolactone can be produced by enzymatic oxidation of D-glucose… »
A drug used to treat diabetes mellitus (a condition in which the body cannot control the level of sugar in the blood… »
Medicamento que se usa para tratar la diabetes mellitus (una afección por la que el cuerpo no puede controlar la concentración de… »
Proteína con moléculas de azúcar adheridas. »
gp100. Antígeno tumoral específico que se usa en el desarrollo de vacunas contra el cáncer. También se llama gp100. »
Medicamento que es un tipo de antimetabolito. Se usa para tratar la neumonía por Pneumocystis carinii y está en estudio para el… »
Tipo de azúcar; la fuente principal de energía para los organismos vivos. »
An amino sugar (2-amino, 2-deoxyglucose) in cell membranes, Glucosamine Sulfate is believed to play a role in cartilage formation and repair. Long-term… »
An oral tablet formulation of a dietary supplement containing the sulfate salts of the amino sugar glucosamine and the glucosaminoglycan chondroitin with… »
Tipo de molécula de polisacáridos larga y no ramificada. Los glucosaminoglicanos son componentes estructurales importantes del cartílago y también se encuentran en… »
A type of sugar; the chief source of energy for living organisms. »
A measurement of the glucose clearance in a sample. »
A condition referring to fasting plasma glucose levels being less than 140 mg per deciliter while the plasma glucose levels after a… »
The determination of the amount of glucose present in a sample. »
A metabolic disorder characterized by abnormal blood glucose levels. »
The determination of the ratio of glucose compared to creatinine present in a sample. The measurement may be expressed as a ratio… »
A test that involves administration of a know quantity of glucose as a means of screening for glucose intolerance or diabetes… »
Glucose Transport Induction consists of the initiation of subcellular or molecular processes directly involved in the physical translocation from one site or… »
Glucose Transport Inhibition involves interference with, or restraint of, subcellular or molecular processes directly involved in the physical translocation from one site… »
Glucose-6-phosphate 1-dehydrogenase (515 aa, ~59 kDa) is encoded by the human G6PD gene. This protein plays a role in pentose metabolism to… »
An inherited disorder in which a person doesn’t have enough of an enzyme called G6PD that helps red blood cells work the… »
The determination of the amount of glucose-6-phosphate dehydrogenase present in a sample. »
Glucose-6-phosphate isomerase (558 aa, ~63 kDa) is encoded by the human GPI gene. This protein is involved in glycolysis in as a… »
Any substance that inhibits glucosidase, specifically alpha-glucosidase in the brush border of the small intestines, an enzyme that catalyzes the breakdown of… »
Compuesto vegetal que contiene azúcar y produce cianuro. »
A class of organic compounds that are derived from a glucose that has been modified by an amino acid. These compounds are… »
A sulfone drug that is converted to dapsone in the body. It has been used to treat mycobacterial infections, including tuberculosis and… »
A sodium salt form of glucosulfone, an agent used to treat mycobacterial infections. »
Glucosylceramidase (536 aa, ~60 kDa) is encoded by the human GBA gene. This protein is involved in glycolipid metabolism. »
A form of a type of sugar called glucose that helps remove harmful substances from the body. Glucuronic acid and the harmful… »
Any substance that inhibits glucuronidase, an enzyme involved in the hydrolysis of glucuronic acid from glucuronides. One of the key processes by… »
An inactivating and detoxification pathway for a variety of exogenous and endogenous molecules, including drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty… »
A substance produced by attaching glucuronic acid to another substance with glycosidic bonds. »
Medicamento contra el cáncer. Es un tipo de alquilante. »
An anticancer drug that belongs to the family of drugs called alkylating agents. »
A long-acting nicotinic acid derivative with antilipidemic activity. Glunicate has more prolonged activity on plasma free fatty acids and triglycerides, with longer… »
Glutamate [NMDA] receptor subunit epsilon-1 (1464 aa, ~165 kDa) is encoded by the human GRIN2A gene. This protein is involved in the… »
Glutamate [NMDA] receptor subunit epsilon-2 (1484 aa, ~166 kDa) is encoded by the human GRIN2B gene. This protein plays a role in… »
Glutamate carboxypeptidase 2 (750 aa, ~84 kDa) is encoded by the human FOLH1 gene. This protein plays a role in the mediation… »
The determination of the amount of glutamate dehydrogenase present in a sample. »
The determination of the amount of glutamate present in a sample. »
Subunit 3 of the AMPA subtype of ionotropic glutamate receptor; important for excitatory neurotransmission »
Glutamate receptor, metabotropic 1 protein (1,194 aa, 132 kD) is a cell communication process protein that is encoded by the human GRM1… »
Glutamate receptor, metabotropic 5 protein (1,212 aa, 132 kD) is a cell communication process protein that is encoded by the human GRM5… »
The metabotropic glutamate receptors are a family of G protein-coupled neurotransmitter receptors, that have been divided into 3 groups on the basis… »
Glutamate--cysteine ligase catalytic subunit (637 aa, ~73 kDa) is encoded by the human GCLC gene. This protein is involved in the biosynthesis… »
Widely expressed (skeletal muscle highest) by human GCLM Gene (Aldo/Keto Reductase Family), 274-aa 31-kDa Gamma-Glutamylcysteine Synthetase Regulatory Protein is the light subunit… »
One of twenty amino acids (molecules that join together to form proteins). Glutamic acid may help nerve cells send and receive information… »
The determination of the amount of glutamic acid decarboxylase 1 present in a sample. »
The determination of the amount of glutamic acid decarboxylase 2 antibody present in a sample. »
The determination of the amount of glutamic acid decarboxylase 2 present in a sample. »
The determination of the amount of glutamic acid decarboxylase antibody present in a sample. »
The hydrochloride salt form of glutamic acid, a non-essential amino acid. Used as a gastric acidifier, glutamic acid hydrochloride releases hydrochloric… »
Aminoácido que se usa en la terapia nutricional. También se encuentra en estudio para el tratamiento de la diarrea provocada por la… »
Glutaminase liver isoform, mitochondrial (602 aa, ~66 kDa) is encoded by the human GLS2 gene. This protein is involved in both glutamine… »
A dual function enzyme derived from bacterial Acinetobacter glutaminasificans used as an adjuvant in chemotherapy. Acinetobacter glutaminase-asparaginase (AGA) possesses both L-glutaminase and… »
An amino acid used in nutrition therapy. It is also being studied for the treatment of diarrhea caused by radiation therapy to… »
Any substance that inhibits glutamine amidotransferase, an enzyme that catalyzes the removal of the ammonia group from glutamine and transfers it to… »
Glutaminyl-peptide cyclotransferase (361 aa, ~41 kDa) is encoded by the human QPCT gene. This protein is involved in the synthesis of cyclic… »
A water-soluble oily liquid, C5H8O2, containing two aldehyde groups, used as a disinfectant and as a fixative for biological tissues. »
A water-soluble oily liquid, C5H8O2, containing two aldehyde groups, used as a disinfectant and as a fixative for biological tissues. »
Glutaredoxin-3 (335 aa, ~37 kDa) is encoded by the human GLRX3 gene. This protein is involved in cellular redox. »
A rare autosomal recessive inherited metabolic disorder caused by deficiency of the enzyme glutaryl-CoA dehydrogenase. It is characterized by abnormalities in the… »
A rare autosomal recessive inherited metabolic disorder caused by mutations in the ETFA, ETFB, or ETFDH genes. It is characterized by deficiency… »
A substance found in plant and animal tissues that has many functions in a cell. These include activating certain enzymes and destroying… »
A stabilized formulation of disodium glutathione disulfide (GSSG; oxidized glutathione) and cisplatin (1000:1) with potential chemoprotective and immunomodulating activities. Mimicking endogenous GSSG,… »
A glutathione (GSH) pegylated, liposome-encapsulated preparation of the hydrochloride salt form of the anthracycline antineoplastic antibiotic doxorubicin, with potential anetineoplastic activity. Upon… »
Glutathione peroxidase 1 (203 aa, ~22 kDa) is encoded by the human GPX1 gene. This protein plays a role in glutathione metabolism,… »
Glutathione peroxidase 2 (190 aa, ~22 kDa) is encoded by the human GPX2 gene. This protein is involved in detoxification and… »
A family of enzymes involved in metabolism and in making toxic compounds less harmful to the body. »
Glutathione S-transferase A1 (222 aa, ~26 kDa) is encoded by the human GSTA1 gene. This protein is involved in glutathione metabolism. … »
A homo- or heterodimeric form of the glutathione S-transferase enzyme that is comprised of two alpha family subunits. »
A homo- or heterodimeric form of the glutathione S-transferase enzyme that is comprised of two mu family subunits. »
Glutathione S-transferase Mu 1 (218 aa, ~26 kDa) is encoded by the human GSTM1 gene. This protein is involved in the metabolism… »
Glutathione S-transferase Mu 3 (225 aa, ~27 kDa) is encoded by the human GSTM3 gene. This protein is involved in cellular detoxification… »
Glutathione S-transferase Mu 4 (218 aa, ~26 kDa) is encoded by the human GSTM4 gene. This protein plays a role in the… »
Glutathione S-transferase P (210 aa, ~23 kDa) is encoded by the human GSTP1 gene. This protein plays a role in xenobiotic metabolism… »
Glutathione S-transferase theta-1 (240 aa, ~27 kDa) is encoded by the human GSTT1 gene. This protein is involved in glutathione metabolism. … »
Any substance that inhibits glutathione transferase, an enzyme that catalyzes the addition of a glutathione moiety to a substrate and is involved… »
The determination of the amount of glutathione-s-transferase present in a sample. »
The determination of the ratio of glutathione-s-transferase compared to creatinine present in a sample. The measurement may be expressed as a ratio… »
Sustancia que se encuentra en los tejidos vegetales y animales, y que desempeña muchas funciones en la célula, como la activación de… »
Tipo de enzimas que participa en el metabolismo y en hacer que los compuestos tóxicos sean menos dañinos para el cuerpo. … »
Any of the skeletal muscles that form the buttocks. These muscles are responsible for hip abduction and extension as well as movement… »
The outermost and largest muscle of the buttocks. »
One of the three gluteal muscles on the lateral surface of the pelvic bone that abducts and rotates the thigh. »
A highly protein bound, longer-acting second-generation sulfonylurea with antihyperglycemic activity. Glyburide, also called glibenclamide, is more likely to cause hypoglycemic episodes due… »
A sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, glybuthiazol is able to lower blood glucose levels by increasing the release of insulin… »
A sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, glybuzole is able to lower blood glucose levels by increasing the release of insulin… »
A large carbohydrate molecule. It contains many small sugar molecules that are joined chemically. Also called polysaccharide. »
A study of the types of carbohydrate (sugar) molecules attached to proteins in cells. Proteins with carbohydrate molecules are called glycoproteins. Glycan… »
Glucose (a type of sugar) found in the blood. Also called blood sugar. »
A measure of the increase in the level of blood glucose (a type of sugar) caused by eating a specific carbohydrate (food… »
Glyceraldehyde-3-phosphate dehydrogenase (335 aa, ~36 kDa) is encoded by the human GAPDH gene. This protein is involved in carbohydrate metabolism. »
A trihydroxyalcohol with localized osmotic diuretic and laxative effects. Glycerin elevates the blood plasma osmolality thereby extracting water from tissues into interstitial… »
An enema solution containing 5% glycerin, a trihydroxy alcohol with osmotic laxative activity. Upon rectal administration, glycerin enema creates an osmotic gradient… »
Glycerol kinase (524 aa, ~57 kDa) is encoded by the human GK gene. This protein plays a role in glycerol metabolism. … »
Slightly viscous, colorless and odorless liquid cyclic ether. Glycidol is used as a stabilizer for natural oils and vinyl polymers, as an… »
A drug that blocks DNA synthesis and may prevent tumor growth. It is being studied as a treatment for cancer. »
A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby… »
An autosomal recessive inherited metabolic disorder caused by mutations in the AMT and GLDC genes. It is characterized by abnormal accumulation of… »
A product from a plant of Asian origin that produces beans used in many food products. Glycine max contains isoflavones (estrogen-like substances)… »
A process that involves the binding of glycine to a glycine receptor. These interactions are involved in various activities, including synaptic plasticity,… »
Serine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis, and glycine is derived from serine. Threonine is an essential amino acid, which… »
An isoflavone with a hydroxyl group on the B-ring and a hydroxy-methyl group on the A-ring. »
A second-generation sulfonylurea with antihyperglycemic activity. Compared to first-generation compounds and like other second-generation compounds, glyclopyramide works more effectively with fewer side… »
Biochemistry of carbohydrates, aldehydic or ketonic derivative of polyhydric alcohols, the name being derived from the fact that the most common examples… »
An extracellular coating of polymeric sugars or glycoproteins. »
A stainable aggregation of glycogen in the cytoplasm. »
A type of inherited disorder in which there are problems with how a form of glucose (sugar) called glycogen is stored and… »
An autosomal recessive inherited type of glycogen storage disease. It is characterized by a deficiency of the enzyme glucose-6-phosphatase, resulting in the… »
An autosomal recessive inherited type of glycogen storage disease caused by deficiency of the enzyme acid alpha-glucosidase. It results in the abnormal… »
A genetic metabolic disorder causing hypertrophic cardiomyopathy. Mutations of the LAMP2 gene have been reported in association with this disease. »
An autosomal recessive inherited type of glycogen storage disease caused by deficiency of the glycogen debranching enzyme. It results in the accumulation… »
A rare inherited type of glycogen storage disease caused by deficiency of amylo-1,4-1,6 transglucosidase. »
An autosomal recessive inherited type of glycogen storage disease caused by deficiency of myophosphorylase. It results in myalgias, muscle cramping and stiffness,… »
A family of serine/threonine protein kinases that is involved in intracellular signaling, cellular proliferation, cell migration, inflammation and immune responses, glucose regulation,… »
Glycogen synthase kinase-3 alpha (483 aa, ~51 kDa) is encoded by the human GSK3A gene. This protein plays a role in protein… »
A carcinoma characterized by the presence of malignant epithelial cells with abundant clear cytoplasm which contains glycogen. A representative example is the… »
A morphologic finding indicating the presence of cells with glycogen-rich cytoplasm. »
An uncommon, usually aggressive adenocarcinoma of the breast characterized by the presence of clear cells that contain glycogen. »
Glycogenesis Induction consists of initiation of activities of biologic molecules or complexes involved in the formation of glycogen from glucose. »
Glycogenesis Inhibition consists of interference with, or restraint of, the activities of biologic molecules or complexes involved in the formation of glycogen… »
Glycogenolysis Induction involves initiation of activities of biologic molecules or complexes involved in the breakdown of glycogen to glucose by hydrolysis or… »
Glycogenolysis Inhibition involves interference with, or restraint of, the activities of biologic molecules or complexes involved in the breakdown of glycogen to… »
An organic chemical and ester of methacrylic acid. Glycol dimethacrylate is a reactive resin used as a functional monomer and a crosslinking… »
A substance found in some fruits, sugar beets, and sugar cane. It is used in skin care products to reduce wrinkles and… »
A process in which glucose (sugar) is partially broken down by cells in enzyme reactions that do not need oxygen. Glycolysis is… »
Glycolysis Induction involves initiation of activities of the pathway by which glucose is catabolized into two molecules of pyruvic acid with the… »
Glycolysis Inhibition involves interference with, or restraint of, the activities of the pathway by which glucose is catabolized into two molecules of… »
In glycolysis, the six-carbon sugar glucose is oxidized and split in two halves, to create two molecules of pyruvate (3 carbons each)… »
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is… »
The collective identity of the entirety of carbohydrates (glycans) in an organism. »
A glycoengineered form of a monoclonal antibody directed against the human epidermal growth factor receptor-2 (HER2), with potential antineoplastic activity. Glycooptimized trastuzumab-GEX… »
A short chain of amino acids (the building blocks of proteins) that has sugar molecules attached to it. Some glycopeptides have been… »
One of a class of antibiotics originally isolated from plant and soil bacteria with structures containing either a glycosylated cyclic or polycyclic… »
A family of sialoglycoproteins that are found in erythrocytes. Members of this family are transmembrane proteins and are able to interact with… »
Glycophorin-A (150 aa, ~16 kDa) is encoded by the human GYPA gene. This protein is involved in red blood cell MN… »
A protein that has sugar molecules attached to it. »
gp100. A tumor-specific antigen used in the development of cancer vaccines. Also called gp100. »
A class of agents that act by selectively inhibiting glycoprotein IIb/IIIa with anticoagulant activity. Glycoprotein IIb/IIIa antagonists bind to and block the… »
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (363 aa, ~42 kDa) is encoded by the human C1GALT1 gene. This protein is involved in mucin-type O-glycan… »
A synthetic quaternary ammonium anticholinergic agent with antimuscarinic activity. Glycopyrrolate binds to peripheral muscarinic receptors and inhibits cholinergic transmission present in the… »
A type of long, unbranched polysaccharide molecule. Glycosaminoglycans are major structural components of cartilage and are also found in the cornea of… »
Glycosaminoglycans (GAGs) are linear polysaccharide chains consisting of repeating disaccharide units and form proteoglycans by covalently attaching to their core proteins. Chondroitin… »
Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, Gal(b1-4)GlcNAc(b1-3), with sulfate esters at C-6 of GlcNAc and… »
Any compound in which a sugar group is covalently bonded through its anomeric carbon to another group via an O-glycosidic bond or… »
An ester containing a sugar component (glycol) and a nonsugar (aglycone) component attached via oxygen or nitrogen bond. Hydrolysis of a glycoside… »
A quantitative measurement of the amount of glycosylated hemoglobin present in a sample of blood. »
A glycosylated form of a recombinant agent that is chemically identical to or similar to endogenous human granulocyte colony-stimulating factor (G-CSF) and… »
A glycosylated recombinant protein which is chemically identical to or similar to endogenous human interleukin-7 (IL-7) with hematopoietic and immunopotentiating activities. Naturally… »
The covalent chemical or biochemical addition of carbohydrate or glycosyl groups to other chemicals, by glycosyl transferases. »
The biosynthesis pathway of N-glycans is a costly system with respect to the number of enzymes that are involved in the synthesis… »
Compounds containing carbohydrate or glycosyl groups linked to phosphatidylinositols. They act to anchor proteins or polysaccharides to cell membranes. »
Cell surface proteins can be attached to the cell membrane via the glycolipid structure called glycosylphosphatidylinositol (GPI) anchor. Hundreds of GPI-anchored proteins… »
An enzyme that catalyzes the transfer of glycosyl groups to an acceptor. The acceptor molecules are frequently carbohydrate molecules, or inorganic… »
Genes that encode the class of enzymes that catalyze the transfer of glycosyl groups to an acceptor; often another carbohydrate molecule, a… »
A cyclohexyl-containing sulfonylurea compound with antihyperglycemic activity. Glycyclamide, also called tolcyclamide, is less potent than glipizide. »
Glycylpeptide N-tetradecanoyltransferase 2 (498 aa, ~57 kDa) is encoded by the human NMT2 gene. This protein is involved in protein myristolation. … »
The dried root of Glycyrrhiza glabra, a legume native to southern Europe and parts of Asia. Licorice root contains glycyrrhizin that is… »
A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to glycyrrhetic acid, which inhibits 11 beta-hydroxysteroid dehydrogenase and… »
A sulfapyrimidine derivative,also known as glycodiazine, with antihyperglycemic activity. Like sulfonylureas, glymidine is able to lower blood glucose levels by increasing the… »
A Danish brand name for a laxative product containing glycerin and docusate sodium. As a hyperosmotic laxative, glycerin draws water into… »
An oxidoreductase that catalyzes the conversion of Coenzyme A to oxalyl-Coenzyme A and the reduction of NADP+ to form NADPH through the… »
A chlorophenyl-containing sulfonylurea with hypoglycemic activity. Glyparamide rarely causes hepatic injury. »
Glypican-3 (580 aa, ~66 kDa) is encoded by the human GPC3 gene. This protein is involved in the mediation of proteoglycan binding… »
Glypican-5 (572 aa, ~64 kDa) is encoded by the human GPC5 gene. This protein plays a role in heparin sulfate binding. … »
Glypican-6 (555 aa, ~63 kDa) is encoded by the human GPC6 gene. This protein plays a role in the mediation of cell-protein… »
A second-generation sulfonylurea with antihyperglycemic activity. Glypinamide, also called azepinamide, is a chlorinated analogue of tolazamide. »
A sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, glyprothiazol is able to lower blood glucose levels by increasing the release of insulin… »
A sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, glysobuzole is able to lower blood glucose levels by increasing the release of insulin… »
A substance that helps make more white blood cells, especially granulocytes, macrophages, and cells that become platelets. It is a cytokine that… »
Expression vectors containing the complementary DNA (cDNA) of the cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) coated onto gold particles. A protein cytokine… »
DNA that encodes granulocyte-macrophage colony stimulating factor (GM-CSF). GM-CSF enhances the host immune response to poorly immunogenic tumors, possibly by activating… »
Heterodimeric human GM-CSF Receptor is composed of Colony Stimulating Factor 2 Receptor Alpha Chain and Colony Stimulating Factor 2 Receptor Beta… »
A recombinant, oncolytic serotype 5/3 capsid-modified adenovirus encoding the immunostimulatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) with potential antineoplastic activity. Upon administration, the… »
A vaccine that is being studied as a way to help the body’s immune system kill breast cancer cells. To make the… »
A cell-based vaccine comprised of K562 cells transfected with the granulocyte macrophage-colony stimulating factor (GM-CSF) gene with potential immunopotentiating properties. Vaccination with… »
A cell-based vaccine composed of irradiated tumor cells transduced with granulocyte-macrophage colony-stimulating factor (GM-CSF) and CD40-ligand (CD40L) genes. Upon administration, this vaccine… »
An autosomal recessive lysosomal storage disease characterized by deficiency of the enzyme acid beta-galactosidase, resulting in the accumulation of acid lipids in… »
A substance used to stimulate the production of antibodies that fight certain cancer cells. »
A cancer vaccine based on the immunogenic ganglioside GM2, The GM2-KLH Vaccine/QS21 vaccine consists of GM2 conjugated with KLH keyhole limpet hemocyanin… »
A trivalent cancer vaccine containing the ganglioside lactones GM2, GD2 and GD3 conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential… »
This gene plays a role in DNA replication regulation. »
Human GMNN wild-type allele is located in the vicinity of 6p22.2 and is approximately 11 kb in length. This allele, which encodes… »
GMP synthase [glutamine-hydrolyzing] (693 aa, ~77 kDa) is encoded by the human GMPS gene. This protein plays a role in the biosynthesis… »
This gene plays a role in nucleotide biosynthesis. »
Human GMPS wild-type allele is located in the vicinity of 3q24 and is approximately 70 kb in length. This allele, which encodes… »
Afección benigna en la que hay una concentración alta de una proteína de la sangre llamada proteína M. Los pacientes de GMSI… »
This gene is involved in signal transduction. »
A laboratory assay to determine the status of the GNA11 gene which encodes guanine nucleotide-binding protein subunit alpha-11. »
A somatic mutation of the GNA11 gene which encodes guanine nucleotide-binding protein subunit alpha-11. »
Human GNA11 wild-type allele is located in the vicinity of 19p13.3 and is approximately 27 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and cytoskeletal remodeling. »
Human GNA12 wild-type allele is located in the vicinity of 7p22.2 and is approximately 116 kb in length. This allele, which encodes… »
This gene is plays a role in signal transduction and is involved in neurotransmission. »
Human GNAI1 wild-type allele is located in the vicinity of 7p21 and is approximately 85 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and neurotransmission. »
Human GNAI2 wild-type allele is located in the vicinity of 3p21 and is approximately 33 kb in length. This allele, which encodes… »
This gene is involved in signal transduction and neurotransmission. »
Human GNAI3 wild-type allele is located in the vicinity of 1p13 and is approximately 45 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and is involved in calcium signaling. »
A laboratory assay to determine the status of the GNAQ gene which encodes guanine nucleotide-binding protein G(q) subunit alpha. »
A somatic mutation of the GNAQ gene which encodes guanine nucleotide-binding protein G(q) subunit alpha. »
Human GNAQ wild-type allele is located in the vicinity of 9q21 and is approximately 315 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and is associated with pituitary tumors. »
Human GNAS wild-type allele is located in the vicinity of 20q13.3 and is approximately 71 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction. It is putatively involved in regulation of the ionic balance of perilymphatic and endolymphatic… »
Human GNAZ wild-type allele is located in the vicinity of 22q11.22 and is approximately 55 kb in length. This allele, which encodes… »
This gene is involved in signal transduction and negative regulation of synaptic transmission. »
Human GNB1 wild-type allele is located in the vicinity of 1p36.33 and is approximately 106 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and is involved in the suppression of glucocorticoid-responsive gene activation. »
Human GNB2 wild-type allele is located within 7q21.3-q22.1 and is approximately 5 kb in length. This allele, which encodes guanine nucleotide-binding protein… »
This gene is plays a role in signal transduction. It is associated with both hypertension and obesity. »
Human GNB3 wild-type allele is located in the vicinity of 12p13 and is approximately 7 kb in length. This allele, which encodes… »
A hormone made by the hypothalamus (part of the brain). GnRH causes the pituitary gland to make luteinizing hormone (LH) and follicle-stimulating… »
A substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are needed to make… »
A substance that blocks the pituitary gland from making hormones called follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In men, this causes… »
This gene is involved in female reproductive regulation and intercellular communication. »
Human GNRH1 wild-type allele is located within 8p21-p11.2 and is approximately 5 kb in length. This allele, which encodes progonadoliberin-1 protein, is… »
This gene plays a role in female reproductive regulation. »
Human GNRH2 wild-type allele is located in the vicinity of 20p13 and is approximately 2 kb in length. This allele, which encodes… »
A substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are needed to make… »
This gene plays a role in the activation of the phosphatidylinositol-calcium second messenger signal transduction pathway. »
Human GNRHR wild-type allele is located in the vicinity of 4q21.2 and is approximately 16 kb in length. This allele, which encodes… »
An object providing entry to a Gene object's position in the Gene Ontology Consortium's controlled vocabularies. »
This object specifies GoOntologyrRelationship. (caBIO) »
A question about whether an individual is able to go shopping for groceries or clothes. »
Any of various hollow-horned, bearded ruminant mammals of the genus Capra, originally of mountainous areas of the Old World, especially any of… »
Cells of the epithelial lining that produce and secrete mucins. »
Proceeding in a satisfactory manner; proceeding as expected or planned. »
An enlarged thyroid. It may be caused by too little iodine in the diet or by other conditions. Most goiters are not… »
An element with atomic symbol Au, atomic number 79, and atomic weight 197. »
Tiny, gold seeds, about the size of a grain of rice, that are put in and/or around a tumor to show exactly… »
Tiny, gold seeds, about the size of a grain of rice, that are put in and/or around a tumor to show exactly… »
The determination of the amount of gold present in a sample. »
Tiny, gold seeds, about the size of a grain of rice, that are put in and/or around a tumor to show exactly… »
The sodium salt of gold thiomalic acid, an organogold compound with antirheumatic and potential antineoplastic activities. Gold sodium thiomalate (GST) appears to… »
A procedure that uses gold salts (a salt form of the metal element gold) to treat diseases, such as rheumatoid arthritis. The… »
Tiny, gold seeds, about the size of a grain of rice, that are put in and/or around a tumor to show exactly… »
The Golden Retriever is a sturdy, well-proportioned dog with a feathered, medium-length, cream to golden-colored coat. The outer coat is water-repellent and… »
A congenital birth defect characterized by incomplete development or absence of face structures, usually affecting one side of the face. The defects… »
A group of North American weedy herbs belonging to the genus Solidago (family Asteraceae) with potential chemopreventive activities. Goldenrod may also possess… »
This gene is involved in Golgi maintenance. »
Human GOLGA5 wild-type allele is located within 14q and is approximately 45 kb in length. This allele, which encodes golgin subfamily A… »
A fusion gene (~2.9 kb) that results from a chromosomal translocation t(10;14)(q11;q32) which fuses the 5' portion of the GOLGA5 gene and… »
A fusion protein (899 aa, ~101 kDa) encoded by the GOLGA5/RET fusion gene. This protein is comprised of 497 N-terminal amino acids… »
Any agent that inhibits golgi alpha-mannosidase II, a mannose-trimming enzyme that is the final hydrolase in the N-glycosylation pathway. Inhibition of golgi… »
A stack of flattened vesicles located between the nucleus and the secretory pole or surface of a cell. Functions in posttranslational processing… »
A stack of small flat sacs formed by membranes inside the cell’s cytoplasm (gel-like fluid). The Golgi body prepares proteins and lipid… »
A stack of small flat sacs formed by membranes inside the cell’s cytoplasm (gel-like fluid). The Golgi complex prepares proteins and lipid… »
Golgi integral membrane protein 4 (696 aa, ~82 kDa) is encoded by the human GOLIM4 gene. This protein plays a role in… »
Golgi phosphoprotein 2 (401 aa, ~45 kDa) is encoded by the human GOLM1 gene. This protein is a type II transmembrane protein… »
1) To direct or use toward the Golgi apparatus as a target. Targeting of the Golgi apparatus by specific substances to… »
The Golgi Tendon Organ is located within the tendons found on each end of a muscle. It responds to increased muscle tension… »
Golgi-associated PDZ and coiled-coil motif-containing protein (462 aa, ~51 kDa) is encoded by the human GOPC gene. This protein plays a role… »
Golgi-associated plant pathogenesis-related protein 1 (154 aa, ~17 kDa) is encoded by the human GLIPR2 gene. This protein may play a role… »
Golgin subfamily A member 5 (731 aa, ~83 kDa) is encoded by the human GOLGA5 gene. This protein is involved in intra-Golgi… »
This gene plays a role in protein targeting. »
Human GOLIM4 wild-type allele is located in the vicinity of 3q26.2 and is approximately 87 kb in length. This allele, which encodes… »
A human monoclonal antibody directed against the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-a) with immunosuppressive activity. Golimumab binds to TNF-a, thereby preventing… »
This gene is involved in both the trafficking and posttranslational modification of proteins. »
Human GOLM1 wild-type allele is located in the vicinity of 9q21.33 and is approximately 74 kb in length. This allele, which encodes… »
A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent… »
An orally bioavailable synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and… »
An orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with… »
Goma de mascar que contiene una dosis pequeña de nicotina, que entra en la sangre al ser absorbida por el revestimiento de… »
IDEC-152 was developed to decrease the body's response to allergens, thereby affecting diseases related to asthma and allergic disorders. This chimeric monoclonal… »
GoMiner is a tool for biological interpretation of 'omic' data, including data from gene expression microarrays. Omic experiments often generate lists of… »
A unit of plane angle measurement equal to 1/400 circle, 0.01 right angle, 0.9 degree, or 0,01570796 rad. The unit is used… »
The part of the reproductive system that produces and releases eggs (ovary) or sperm (testicle/testis). »
La parte del sistema reproductor que produce y libera óvulos (ovarios) o esperma (testículos). »
A congenital disorder characterized by the complete absence of gonadal tissue. »
A non-neoplastic or neoplastic disorder that affects the testis or the ovary. »
Abnormal development of a gonad (ovary or testicle). Men with gonadal dysgenesis have a greater risk of developing testicular cancer. Gonadal dysgenesis… »
A rare malignant germ cell tumor arising from the testis and less often from the ovary. It is characterized by the presence… »
A procedure used to help keep a person fertile by preventing damage to reproductive organs during radiation therapy. A protective shield is… »
A teratoma that arises from the testis or ovary. »
A mixed germ cell/sex cord-stromal tumor characterized by the presence of large germ cells which resemble seminoma cells and small cells which… »
An endocrine cell of the adenohypophysis that affects certain cells of the ovary or testis. »
Specifically expressed in hypothalamic neurons as a preproprotein, Gonadotropin Releasing Hormones (GnRH Family) are secreted into the median eminence capillary plexus, bind… »
Heterodimeric glycoprotein Gonadotropin consists of alpha (common)/beta (unique) protein subunits. The alpha subunit is present in other heterodimeric glycoprotein hormones. The beta… »
Specifically expressed as a 92-aa 10-kDa precursor in a small population of hypothalamic neurons by human GNRH1 Gene (GnRH Family), Gonadotropin Releasing… »
Expressed as preproprotein in the midbrain, and at higher levels in the kidney, bone marrow, and prostate, by human GNRH2 Gene (GnRH… »
A synthetic peptide that competes with the neurohormone GnRH for its receptor, thus decreasing or blocking GnRH action. As a result endogenous… »
The determination of the amount of gonadotropin releasing hormone present in a sample. »
An abnormality of gonadotropin production resulting in abnormal levels of circulating gonadotropin. »
Premature onset of sexual development triggered by the premature secretion of gonadotropins. »
Premature development of secondary sexual characteristics due to the presence of sex steroids independent of pituitary gonadotropin release. »
An adenoma of the anterior lobe of the pituitary gland that produces gonadotrophic hormones (FSH and/or LH) or shows evidence towards gonadotroph… »
A hormone made by the hypothalamus (part of the brain). GnRH causes the pituitary gland to make luteinizing hormone (LH) and follicle… »
A substance that keeps the testicles and ovaries from making sex hormones by blocking other hormones that are needed to make… »
A hormone made in the laboratory that has the same effect as the gonadotropin-releasing hormone (GnRH) produced naturally by the body. … »
A substance that blocks the pituitary gland from making hormones called follicle-stimulating hormone (FSH) and luteinizing hormone (LH). In men, this causes… »
Gonadotropin-releasing hormone receptor protein (328 aa, 38 kD) is a cell communication process protein that is encoded by the human GNRHR gene… »
Gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus acts upon its receptor in the anterior pituitary to regulate the production and release of… »
Hormona que se encuentra en la sangre y la orina durante el embarazo. También se puede encontrar en cantidades más altas que… »
A monounsaturated long-chain fatty acid with a 20-carbon backbone and the sole double bond originating from the 9th position from the methyl… »
Procedimiento en el cual se usa un gonioscopio (lente especial) para observar la parte anterior del ojo entre la córnea (la capa… »
A procedure in which a gonioscope (special lens) is used to look at the front part of the eye between the cornea… »
La gonorrea es una enfermedad de transmisión sexual curable. Es más común en los adultos jóvenes. La bacteria que causa la gonorrea… »
A common sexually transmitted bacterial infection caused by Neisseria gonorrhea. It is transmitted through vaginal, oral, or anal intercourse. Infected individuals may… »
An alternative therapy that is being studied as a treatment for pancreatic cancer. It includes a special diet, nutritional supplements, pancreatic enzymes,… »
Valuable or useful or agreeable or pleasing. »
An international set of guidelines that helps make sure that the results of a clinical trial are reliable and that the patients… »
A classification of the good laboratory practices employed in a study. »
Metastatic gestational trophoblastic tumor in which risk factors are absent. »
An autoimmune disorder characterized by pulmonary hemorrhage and glomerulonephritis. It is a hypersensitivity reaction resulting in the formation of antibodies against the… »
This gene plays a role in protein transport. »
Human GOPC wild-type allele is located in the vicinity of 6q21 and is approximately 284 kb in length. This allele, which encodes… »
A fusion gene (~4.1 kb) that results from an interstitial deletion of 240 kb on 6q21 which fuses the first 7 exons… »
A fusion protein (878, ~109 kDa) encoded by the GOPC/ROS1 fusion gene. This protein is comprised of most of the Golgi-associated PDZ… »
The Gordon Setter is the only black and tan setter. It has a feathered coat and a long, chiseled and massive… »
A genus of aerobic, Gram positive, coryneform bacterium assigned to the phylum Actinobacteria and the family Gordoniaceae. »
A species of aerobic, Gram positive, coryneform bacteria assigned to the phylum Actinobacteria. This species is catalase positive, slightly acid fast, nonmotile… »
A species of aerobic, Gram positive, coryneform bacteria assigned to the phylum Actinobacteria. This species is catalase positive, slightly acid fast, nonmotile… »
A species of aerobic, Gram positive, coryneform bacteria assigned to the phylum Actinobacteria. This species is catalase positive, slightly acid fast, nonmotile… »
A species of aerobic, Gram positive, coryneform bacteria assigned to the phylum Actinobacteria. This species is catalase positive, slightly acid fast, nonmotile… »
A species of aerobic, Gram positive, coryneform bacteria assigned to the phylum Actinobacteria. This species is catalase positive, oxidase negative, nonmotile and… »
A taxonomic family of bacterium in the phylum Actinobacteria that includes the genera Gordonia and Millisia, among others. »
A genetic condition that causes unusual facial features and disorders of the skin, bones, nervous system, eyes, and endocrine glands. People with… »
A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH)… »
A drug used to treat prostate cancer and to relieve the symptoms of advanced breast cancer. It is also used to treat… »
Sustancia en estudio para el tratamiento de varios tipos de cáncer. Proviene de la semilla de la planta de algodón (Gossypium). Impide… »
A potent, selective and orally bioavailable, difluoropyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. »
A substance being studied in the treatment of several types of cancer. It comes from the seed of the cotton plant… »
A substance being studied in the treatment of several types of cancer. It is a form of a chemical taken from the… »
This gene plays a role in amino acid metabolism, the tricarboxylic acid cycle and the urea cycle. »
Human GOT1 wild-type allele is located within 10q24.1-q25.1 and is approximately 34 kb in length. This allele, which encodes aspartate aminotransferase, cytoplasmic… »
This gene is involved in the tricarboxylic acid cycle, urea cycle and amino acid metabolism. »
Human GOT2 wild-type allele is located within 16q21 and is approximately 27 kb in length. This allele, which encodes aspartate aminotransferase, mitochondrial… »
Afección caracterizada por un aumento en la concentración de ácido úrico en la sangre, coyunturas y tejidos. La concentración de ácido úrico… »
The smallest of the common miniature breeds, this breed is 10-14kg at sexual maturity with a shortened snout and rounded appearance. The… »
A condition marked by increased levels of uric acid in the blood, joints, and tissue. The buildup of uric acid in… »
The political organization by which a state or nation is ruled. »
Fiscal support from governmental organizations. »
A coded value specifying the unique identifier for areas of extramural research activity applied to various funding mechanisms. »
A two letter coded value specifying the first major-level subdivision of the organization that supports a grant, contract, or inter-agency agreement. The… »
A character string that represents the six-digit number generally assigned sequentially to a funding mechanism within an institute, center, or division. … »
A coded value specifying the kind of application received and processed. »
A recombinant HIV gp120 envelope protein with potential use in HIV vaccine therapy. Gp-120 antigen is used to elicit a gp120-specific T-cell… »
A tumor-specific antigen used in the development of cancer vaccines. Also called glycoprotein 100. »
Glicoproteína 100. Antígeno tumoral específico que se usa en el desarrollo de vacunas contra el cáncer. También se llama glucoproteína 100. … »
A vaccine consisting of a replication-defective recombinant adenovirus that encodes the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. Vaccination with… »
A vaccine consisting of microscopic gold particles coated with plasmid DNA encoding the glycoprotein 100 (gp100) melanoma antigen and granulocyte-macrophage colony-stimulating factor… »
A melanoma-associated antigen. When administered in a vaccine formulation, gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against… »
A synthetic agent derived from the tumor-associated differentiation antigen gp100 DNA. Gp100 DNA is coated onto microscopic gold beads and used… »
A vaccine consisting of synthetic glycoprotein 100 (gp100) melanoma antigen and incomplete Freund's adjuvant (IFA), an emulsifying agent and immune system stimulant,… »
A population of CD4+ and CD8+ T-cells isolated from a cancer patient that have been sensitized in vitro to the melanoma-associated antigen… »
A recombinant peptide derived from the human melanoma antigen glycoprotein 100 (gp100) with potential use in cancer immunotherapy. gp100 protein(184V) has a… »
A cancer vaccine consisting of a recombinant vaccinia virus encoding the gp100 melanoma-melanocyte antigen. gp100 human antigen is a wild-type self-antigen expressed… »
A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the melanoma antigen glycoprotein 100 (gp 100) with potential antineoplastic… »
Peripheral blood lymphocytes (PBL) harvested from host blood and stimulated in vitro with tumor-specific gp 100 antigen. 'Pulsing' PBL with gp100, a… »
Human peripheral blood lymphocytes (PBL) isolated from a patient, exposed to the tumor-associated antigen gp100 in vitro, and then transferred back to… »
Tumor infiltrating lymphocytes (TIL) isolated from a patient, exposed to the tumor-associated antigen gp100 in vitro, and then transferred back to the… »
A synthetic peptide vaccine consisting of amino acids 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen with an endoplasmic reticulum… »
A peptide consisting of amino acid residues 154 through 162 of the melanoma-melanocyte antigen gp100. Vaccination with gp100:154-162 peptide may enhance tumor-specific… »
A synthetic peptide vaccine consisting of amino acids 17 through 25 of the glycoprotein 100 (gp100) melanoma antigen. Vaccination with gp100_17-25… »
A synthetic peptide vaccine consisting of the amino acids 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen. Vaccination with… »
A synthetic peptide cancer vaccine consisting of amino acid residues 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen, with a… »
A vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. … »
A peptide vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic… »
A synthetic peptide vaccine consisting of the amino acids 44 through 59 of the glycoprotein 100 (gp100) melanoma antigen. Vaccination with… »
A synthetic peptide consisting of amino acid residues 614 through 622 of the melanoma-melanocyte antigen glycoprotein 100 (gp100). Vaccination with gp100:614-622 peptide… »
A vaccine containing a HER2/Neu-derived epitope (amino acids 654-662) (GP2), and combined with granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential antineoplastic and immunoadjuvant… »
A peptide (short piece of protein) made from the tumor-specific antigen gp100, and used to make vaccines being studied in the treatment… »
Un péptido (segmento corto de proteína) elaborado del antígeno gp100 tumoral específico y que se usa para producir vacunas que se encuentran… »
A modified peptide antigen derived from gp209, with potential immunomodulatory and antineoplastic activities. gp209-2M antigen (IMDQVPFSV) has a methionine substitution of threonine… »
A vaccine made from a patient’s tumor cells that may help the body’s immune system kill cancer cells. This vaccine is used… »
A vaccine made from a patient’s tumor cells that may help the body’s immune system kill cancer cells. This vaccine is used… »
A proprietary, allogeneic tumor cell vaccine expressing a recombinant secretory form of the heat shock protein gp96 fusion (gp96-Ig) with potential antineoplastic… »
This gene plays a role in transcription and is a member of the immunoglobulin superfamily. »
Human GPA33 wild-type allele is located in the vicinity of 1q24.1 and is approximately 38 kb in length. This allele, which encodes… »
This gene may be involved in transcriptional regulation. »
Human GPBP1L1 wild-type allele is located in the vicinity of 1p34.1 and is approximately 61 kb in length. This allele, which encodes… »
This gene is involved in heparin sulfate binding. »
Human GPC3 wild-type allele is located in the vicinity of Xq26.1 and is approximately 622 kb in length. This allele, which encodes… »
This gene plays a role in cellular interactions with proteoglycans. »
Human GPC5 wild-type allele is located in the vicinity of 13q32 and is approximately 2671 kb in length. This allele, which encodes… »
This gene plays a role in protein binding. »
Human GPC6 wild-type allele is located in the vicinity of 13q32 and is approximately 1181 kb in length. This allele, which encodes… »
Homologous desensitization of GPCRs results from the binding of b-arrestins (b-arr) to agonist -occupied receptors following phosphorylation of the receptor by… »
The binding of b-arrestins to agonist-occupied GPCRs coincides with the recruitment of Src family tyrosine kinases, including c-Src, Hck and c-Fgr (Src-TK),… »
This gene plays a role in both estrogen binding and G protein-coupled receptor signaling. »
Human GPER wild-type allele is located in the vicinity of 7p22.3 and is approximately 12 kb in length. This allele, which encodes… »
This gene is involved in vitamin metabolism. »
Human GPHN wild-type allele is located in the vicinity of 14q23.3 and is approximately 674 kb in length. This allele, which encodes… »
This gene plays a role in glycolysis, gluconeogenesis and energy pathways. »
Human GPI wild-type allele is located in the vicinity of 19q13.1 and is approximately 35 kb in length. This allele, which encodes… »
A semi-synthetic triterpene glycoside, derived from the naturally occurring saponins. GPI-0100 functions as an adjuvant when given as part of a vaccine… »
This gene may play a role in the regulation of cell proliferation. »
Human GPNMB wild-type allele is located in the vicinity of 7p15 and is approximately 39 kb in length. This allele, which encodes… »
This gene is involved in G protein-coupled receptor signal transduction and nicotinic acid receptor activity. »
Human GPR109B wild-type allele is located in the vicinity of 12q24.31 and is approximately 2 kb in length. This allele, which encodes… »
This gene plays a role in fatty acid binding and glucagon-like peptide 1 secretion. »
Human GPR120 wild-type allele is located in the vicinity of 10q23.33 and is approximately 23 kb in length. This allele, which encodes… »
This gene is involved in G protein-coupled receptor signal transduction but an exact function is not known. »
Human GPR17 wild-type allele is located within 2q21 and is approximately 9 kb in length. This allele, which encodes probable P2Y purinoceptor… »
Human GPR183 wild-type allele is located in the vicinity of 13q32.3 and is approximately 13 kb in length. This allele, which encodes… »
This gene is involved in humoral immunity. »
This gene is involved in G protein-coupled receptor signal transduction. »
Human GPR32 wild-type allele is located in the vicinity of 19q13.3 and is approximately 1 kb in length. This allele, which encodes… »
This gene is involved in G protein-coupled receptor signal transduction and the regulation of growth factor release. »
Human GPR39 wild-type allele is located within 2q21-q22 and is approximately 230 kb in length. This allele, which encodes probable G-protein coupled… »
This gene is involved in both brain development and signaling. »
Human GPR56 wild-type allele is located in the vicinity of 16q13 and is approximately 45 kb in length. This allele, which encodes… »
This gene is involved in G protein-coupled receptor signal transduction and pH homeostasis. »
Human GPR68 wild-type allele is located within 14q31 and is approximately 20 kb in length. This allele, which encodes sphingosylphosphorylcholine receptor protein,… »
This gene plays a role in G protein-coupled receptor signal transduction and is purported to play a role in embryonic development and… »
Human GPRC5A wild-type allele is located within 12p13-p12.3 and is approximately 22 kb in length. This allele, which encodes retinoic acid-induced protein… »
This gene plays a role in G protein-coupled receptor signal transduction but the specific function of this protein is unknown. »
Human GPRC5C wild-type allele is located within 17q25 and is approximately 20 kb in length. This allele, which encodes G-protein coupled receptor… »
This gene is involved in suppression of signal transduction. »
Human GPS1 wild-type allele is located in the vicinity of 17q25.3 and is approximately 6 kb in length. This allele, which encodes… »
This gene plays a role in suppression of signal transduction. »
Human GPS2 wild-type allele is located in the vicinity of 17p13 and is approximately 17 kb in length. This allele, which encodes… »
This gene is involved in amino acid metabolism and liver gluconeogenesis. »
Human GPT wild-type allele is located in the vicinity of 8q24.3 and is approximately 4 kb in length. This allele, which encodes… »
This gene plays a role in amino acid metabolism, liver gluconeogenesis and the homeostasis of fatty acid metabolism and storage. »
Human GPT2 wild-type allele is located in the vicinity of 16q12.1 and is approximately 47 kb in length. This allele, which encodes… »
An anticancer drug that belongs to the family of drugs called antitumor antibiotics. It is an anthracycline. »
Medicamento contra el cáncer que es un tipo de antibiótico antitumoral. Es una antraciclina. »
This gene plays a role in the inhibition of oxidative stress and increases cellular resistance to toxic challenges. »
Human GPX1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 12 kb in length. This allele, which encodes… »
This gene is involved in digestion. »
Human GPX2 wild-type allele is located in the vicinity of 14q23.3 and is approximately 4 kb in length. This allele, which encodes… »
Encoded by human GR6 Gene, the function of 149-aa 16-kDa GR6 Protein is unknown. »
Any of the fluid-filled vesicles in the mammalian ovary containing a maturing ovum. »
A length of time beyond a specified date during which rules or penalties are withheld. »
A visual analog scale of 0 to 20, used by a subject to define their pain intensity experience. Together with the… »
A visual analog scale of 0 to 20 used by a subject to define their pain unpleasantness experience. Together with the… »
A genus of motile, Gram positive, endospore forming rod shaped bacterium assigned to the phylum Firmicutes and the family Bacillaceae. »
The most superficial muscle extending vertically downward along the inner thigh which adducts the thigh, rotates the leg medially and flexes the… »
A position on a scale of intensity or amount or quality. »
A morphologic qualifier indicating that a cancerous lesion is well differentiated. »
A colon adenocarcinoma characterized by the presence of a malignant cellular infiltrate with more than 95% glandular formation. »
A colorectal adenocarcinoma characterized by the presence of a malignant cellular infiltrate with more than 95% glandular formation. »
A primary endometrioid adenocarcinoma of the endometrium that contains equal to or less than 5% non-squamous solid areas. »
A primary mucinous adenocarcinoma of the endometrium that contains equal to or less than 5% non-squamous solid areas. »
An indolent (slow-growing) type of non-Hodgkin lymphoma marked by enlarged lymph nodes and small cells that have cleaved (u-shaped) nuclei. »
An immature teratoma that arises from the ovary and is characterized by the presence of rare foci of immature neuroepithelial tissue that… »
Intraventricular hemorrhage of the newborn that is limited to the germinal matrix. »
A well differentiated invasive breast carcinoma. »
Nodular sclerosis Hodgkin lymphoma in which at least 75% of the tumor nodules contain scattered Reed-Sternberg cells. The background cellular infiltrate is… »
A rectal adenocarcinoma characterized by the presence of a malignant cellular infiltrate with more than 95% glandular formation. »
A morphologic qualifier indicating that a cancerous lesion is moderately differentiated. »
A colon adenocarcinoma characterized by the presence of a malignant cellular infiltrate with 50-95% glandular formation. »
A colorectal adenocarcinoma characterized by the presence of a malignant cellular infiltrate with 50-95% glandular formation. »
A primary endometrioid adenocarcinoma of the endometrium that contains 6-50% non-squamous solid areas. »
A primary mucinous adenocarcinoma of the endometrium that contains 6-50% non-squamous solid areas. »
An indolent (slow-growing) type of non-Hodgkin lymphoma marked by enlarged lymph nodes and a mix of large cells and small cells that… »
An immature teratoma that arises from the ovary and is characterized by the presence of foci of immature neuroepithelial tissue that occupy… »
Intraventricular hemorrhage of the newborn that is found in the ventricles. There is no change in the size of the ventricles. … »
A moderately differentiated invasive breast carcinoma. »
Nodular sclerosis Hodgkin lymphoma in which at least 25% of the tumor nodules contain increased numbers of Reed-Sternberg cells. »
A rectal adenocarcinoma characterized by the presence of a malignant cellular infiltrate with 50-95% glandular formation. »
Vaginal intraepithelial neoplasia characterized by the presence of nuclear intraepithelial neoplastic changes in the lower two-thirds of the epithelium and parakeratosis. … »
Intraepithelial neoplasia that affects the vulvar epithelium and is characterized by the presence of moderate dysplasia. »
A morphologic qualifier indicating that a neoplastic lesion is moderately to poorly differentiated. »
A morphologic qualifier indicating that a cancerous lesion is poorly differentiated. »
A colon adenocarcinoma characterized by the presence of a malignant cellular infiltrate with less than 50% glandular formation. »
A colorectal adenocarcinoma characterized by the presence of a malignant cellular infiltrate with less than 50% glandular formation. »
A primary endometrioid adenocarcinoma of the endometrium that contains more than 50% non-squamous solid areas. »
A primary mucinous adenocarcinoma of the endometrium that contains more than 50% non-squamous solid areas. »
A type of non-Hodgkin lymphoma marked by large cells and enlarged lymph nodes. Grade 3 follicular lymphoma is less common, and more… »
An immature teratoma that arises from the ovary and is characterized by the presence of large amounts of immature neuroepithelial tissue that… »
Intraventricular hemorrhage of the newborn that is found in the ventricles. It is associated with dilatation of the ventricles. »
A poorly differentiated invasive breast carcinoma. »
A rectal adenocarcinoma characterized by the presence of a malignant cellular infiltrate with less than 50% glandular formation. »
A grade 3 follicular lymphoma in which centrocytes are present. »
A grade 3 follicular lymphoma composed of solid sheets of centroblasts. »
A morphologic qualifier indicating that a cancerous lesion is undifferentiated. »
A coded value specifying the position on a scale of intensity or amount or quality. »
A benign meningioma which may recur in approximately 7-20% of the cases. This category includes the angiomatous meningioma, fibrous meningioma, lymphoplasmacyte-rich… »
Vesicoureteral reflux in which there is urine reflux into the ureter only. »
An atypical meningioma which may recur in approximately 29-40% of the cases. This category includes the atypical meningioma, chordoid meningioma, and… »
Penile intraepithelial neoplasia characterized by the proliferation of transformed basaloid cells that occupy the lower two thirds of the epithelial thickness. … »
High grade prostatic intraepithelial neoplasia characterized by the presence of moderate architectural and cytologic abnormalities. »
Vesicoureteral reflux in which there is urine reflux into the ureter and renal pelvis. There is no dilatation of the ureter and… »
A high grade intraepithelial neoplasia in which there is marked architectural distortion and crowding of the glands, associated with severe cellular… »
Lymphomatoid granulomatosis characterized by the presence of aggregates of neoplastic large B-lymphocytes, usually admixed with pleomorphic and Hodgkin-like cells, in a background… »
A malignant meningioma with aggressive clinical course. It recurs in approximately 50-78% of the cases. This category includes the anaplastic… »
High grade prostatic intraepithelial neoplasia characterized by the presence of severe architectural and cytologic abnormalities. »
Vesicoureteral reflux in which there is urine reflux into the ureter and renal pelvis. Mild dilatation of the ureter and the calyces… »
A fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has… »
Vesicoureteral reflux in which there is urine reflux into the ureter and renal pelvis. Moderate dilatation of the ureter and the calyces… »
A school for young children; usually the first 6 or 8 grades. »
Vesicoureteral reflux in which there is urine reflux into the ureter and renal pelvis. Severe tortuosity and dilatation of the ureter and… »
A graded change in the magnitude of some physical quantity or dimension. »
A method to determine microbial susceptibility to antibiotics in which an agar plate, which has a concentration gradient of the drug within… »
An artifact that results from a gradient which is not constant with respect to the gradient direction. »
Issue associated with the increased rate of change in temperature, pressure, or other variables as a function of distance, time, etc. … »
A system for classifying cancer cells in terms of how abnormal they appear when examined under a microscope. The objective of a… »
Término que se usa para describir células y tejidos con apariencia anormal al microscopio. Las células cancerosas de grado alto tienden a… »
Término que se usa para describir células y tejidos con apariencia casi normal al microscopio. Las células cancerosas de grado bajo… »
Sistema de clasificación usado para describir la solidez de los resultados medidos en un ensayo clínico o estudio de investigación. El diseño… »
Descripción de un tumor según cuán anormales se vean las células cancerosas bajo un microscopio y con qué rapidez es posible que… »