Library / English Dictionary

IMMUNOGLOBULIN

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response

Synonyms:

Ig; immune gamma globulin; immune globulin; immune serum globulin; immunoglobulin

Classified under:

Nouns denoting substances

Hypernyms ("immunoglobulin" is a kind of...):

gamma globulin; human gamma globulin (a plasma protein containing the immunoglobulins that are responsible for immune responses)

antibody (any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response)

Hyponyms (each of the following is a kind of "immunoglobulin"):

IgA; immunoglobulin A (one of the most common of the five major classes of immunoglobulins; the chief antibody in the membranes of the gastrointestinal and respiratory tracts)

IgD; immunoglobulin D (one of the five major classes of immunoglobulins; present in blood serum in small amounts)

IgE; immunoglobulin E (one of the five major classes of immunoglobulins; present primarily in the skin and mucous membranes)

IgG; immunoglobulin G (one of the five major classes of immunoglobulins; the main antibody defense against bacteria)

IgM; immunoglobulin M (one of the five major classes of immunoglobulins; involved in fighting blood infections and in triggering production of immunoglobulin G)

tetanus immune globulin; tetanus immunoglobulin (sterile solution of globulins derived from the blood plasma of a person who has been immunized for tetanus; provides short-term immunization against tetanus in cases of possible exposure to the tetanus bacillus)

Credits

 Context examples: 

A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum.

(Monoclonal gammopathy of undetermined significance, NCI Thesaurus)

B cells produce immunoglobulins (Ig, antibodies) that specifically bind antigen molecules.

(B Cell Receptor Complex Signaling Pathway, NCI Thesaurus/BIOCARTA)

This gene is involved in immunoglobulin binding.

(MS4A2 Gene, NCI Thesaurus)

An antibody is a type of immunoglobulin.

(Antibody, NCI Dictionary)

Different immunoglobulin subclasses and isotypes are associated with different diseases and conditions.

(Anticardiolipin Antibody, NCI Thesaurus)

Only the light chain (kappa or lambda) of the immunoglobulin is defective.

(Multiple Myeloma-Light Chain Only, NCI Thesaurus)

The heavy chain, IgM, of the immunoglobulin is defective.

(Multiple Myeloma-IgM (not Waldenstrom Macroglobulinemia), NCI Thesaurus)

A purified gamma immunoglobulin (IgG) with immunosuppressive activity.

(Anti-Thymocyte Globulin, NCI Thesaurus)

Any immunoglobulin that recognizes prostatic acid phosphatase.

(ACPP Antibody, NCI Thesaurus)

There is clonal rearrangement of the immunoglobulin or the T-cell receptor genes.

(Neoplastic Post-Transplant Lymphoproliferative Disorder, NCI Thesaurus)