| Library / English Dictionary |
ANTIBODY
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
Classified under:
Hypernyms ("antibody" is a kind of...):
protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)
Meronyms (parts of "antibody"):
active site (the part of an enzyme or antibody where the chemical reaction occurs)
Hyponyms (each of the following is a kind of "antibody"):
autoantibody (an antibody acting against tissues of the organism that produces it)
precipitin (an antibody that causes precipitation when it unites with its antigen)
ABO antibodies (blood type antibodies)
Rh antibody (rhesus factor antibody)
antitoxin (an antibody that can neutralize a specific toxin)
agglutinin (an antibody that causes agglutination of a specific antigen)
Forssman antibody; heterophil antibody; heterophile antibody (an antibody found in the blood of someone suffering from infectious mononucleosis)
alloantibody; isoantibody (an antibody that occurs naturally against foreign tissues from a person of the same species)
monoclonal; monoclonal antibody (any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules)
opsonin (an antibody in blood serum that attaches to invading microorganisms and other antigens to make them more susceptible to the action of phagocytes)
Ig; immune gamma globulin; immune globulin; immune serum globulin; immunoglobulin (a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response)
Context examples:
ZMapp is composed of 3 different monoclonal antibodies (mAbs).
(Experimental Ebola antibody protects monkeys, NIH)
Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells.
(ABX-EGF, NCI Dictionary)
Pathogenesis involves immune dysfunction with antibodies directed against erythroid precursor cells or erythropoietin, or due to T-cell mediated suppression of erythropoiesis.
(Acquired pure red cell aplasia, NCI Thesaurus)
MILs are harvested from autologous bone marrow from multiple myeloma patients and, in vitro, are exposed to and activated by anti-CD3/anti-CD28 monoclonal antibodies covalently attached to super-paramagnetic microbeads.
(Activated Marrow Infiltrating Lymphocytes, NCI Thesaurus)
A recombinant, human IgG1 monoclonal antibody directed against tumor necrosis factor-alpha (TNF-alpha), with immunomodulating activity.
(Adalimumab, NCI Thesaurus)
Several therapeutic agents can be utilized to this end, such as drugs and monoclonal antibodies.
(Metastatic Inhibitory Effect, NCI Thesaurus)
The samples are usually DNA fragments but may also be antibodies, other proteins, or tissues.
(Microarray, NCI Thesaurus)
Also called Ch14.18 and monoclonal antibody Ch14.18.
(MOAB Ch14.18, NCI Dictionary)
A monoclonal antibody directed against the neurohormone bombesin that is conjugated to isothiocyanobenzyl diethylenetriaminepentaacetic acid (ITC-D), a bifunctional chelating agent that allows the antibody to be labeled with a metal species.
(MoAb Bombesin (ITC-D), NCI Thesaurus)
A monoclonal antibody B3, recognizing the tumor-associated Lewis Y antigen, is conjugated to a backbone-substituted derivative of DTPA, 2-(p-isothiocyanatobenzyl)-cyclohexyl-diethylenetriaminepentaacetic acid (CHX-A DTPA).
(MOAB B-3-CHX-A-DTPA, NCI Thesaurus)
