KIT wt Allele

Human KIT wild-type allele is located within 4q11-q12 and is approximately 83 kb in length. This allele, which encodes mast/stem cell growth factor receptor protein, plays a role in the mediation of transmembrane-receptor interactions. Mutations in the gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. (NCI Thesaurus)

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Kit Number

A number or sequence of characters that identifies a particular kit.

Kit ligand

A substance that causes blood stem cells (cells from which other types of cells develop) to change into different types of blood…

KIT Gene Mutation

A molecular genetic abnormality that refers to mutation of the c-kit (CD117) proto-oncogene. It is associated with the development of gastrointestinal stromal…

KIT Gene

This gene plays a role in cellular hematopoiesis and differentiations. Mutations in the gene are associated with several diseases, including acute myelogenous…

KIT Exon 9 Mutation

A molecular genetic abnormality indicating the presence of a mutation in exon 9 of the KIT gene located within 4q11-q12.

KIT Exon 13 Mutation

A molecular genetic abnormality indicating the presence of a mutation in exon 13 of the KIT gene located within 4q11-q12.