LATS2 wt Allele

Human LATS2 wild-type allele is located within 13q11-q12 and is approximately 87 kb in length. This allele, which encodes serine/threonine-protein kinase LATS2 protein, is involved in centrosome duplication and the maintenance of mitotic fidelity. Down-regulation of LATS1 gene expression by promoter hypermethylation is associated with an aggressive phenotype in breast cancer. (NCI Thesaurus)

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LATS2 Gene

This gene plays a role in the maintenance of genomic stability.

LATS1 wt Allele

Human LATS1 wild-type allele is located within 6q24-q25.1 and is approximately 108 kb in length. This allele, which encodes serine/threonine-protein kinase LATS1…

LATS1 Gene

This gene is involved in the maintenance of genomic stability.

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