Library / English Dictionary

    LEUKEMIA

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancerplay

    Synonyms:

    cancer of the blood; leucaemia; leukaemia; leukemia

    Classified under:

    Nouns denoting stable states of affairs

    Hypernyms ("leukemia" is a kind of...):

    cancer; malignant neoplastic disease (any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream)

    Hyponyms (each of the following is a kind of "leukemia"):

    acute leukemia (rapidly progressing leukemia)

    chronic leukemia (slowly progressing leukemia)

    lymphocytic leukemia (leukemia characterized by enlargement of lymphoid tissues and lymphocytic cells in the circulating blood)

    histiocytic leukaemia; histiocytic leukemia; monoblastic leukaemia; monoblastic leukemia; monocytic leukaemia; monocytic leukemia (leukemia characterized by the proliferation of monocytes and monoblasts in the blood)

    myeloblastic leukemia (a malignant neoplasm of blood-forming tissues; characterized by numerous myeloblasts in the blood stream)

    granulocytic leukemia; myelocytic leukemia (a malignant neoplasm of blood-forming tissues; marked by proliferation of myelocytes and their presence in the blood)

    Credits

     Context examples: 

    This gene is involved in the regulation of gene expression and is proposed to act as an oncogene in a broad variety of leukemias as well as colon, pancreatic and prostate carcinomas.

    (MIR106A Gene, NCI Thesaurus)

    Alteration in the expression of this gene is associated with development of T-cell leukemia.

    (MIR106A wt Allele, NCI Thesaurus)

    Also called acute lymphocytic leukemia and ALL.

    (Acute lymphoblastic leukemia, NCI Dictionary)

    The term basophilic leukemia is used as a synonym for acute basophilic leukemia.

    (Acute Basophilic Leukemia, NCI Thesaurus/WHO)

    Alteration in the expression of this gene is associated with the development of cancers of the lung, liver, colon, breast and prostate as well as leukemias.

    (MIR126 wt Allele, NCI Thesaurus)

    This rearrangement is associated with chronic myelogenous leukemia, acute lymphoblastic leukemia and acute myeloid leukemia.

    (ABL1/BCR Fusion Gene, NCI Thesaurus)

    The ABL2 gene is translocated in acute myelogenous leukemia.

    (ABL2 wt Allele, NCI Thesaurus)

    The ABL1 gene is translocated in chronic myelogeneous leukemia, acute lymphoblastic leukemia and, in rare cases, acute myelogenous leukemia.

    (ABL1 wt Allele, NCI Thesaurus)

    The development of myeloid leukemia is a very rare adverse effect of some types of cancer treatments that damage cell.

    (Study finds elevated risk of certain rare blood cancers after chemotherapy for most solid tumors, National Institutes of Health)

    Alteration in the expression of this gene is associated with the development of cancers of the liver, pituitary and prostate as well as leukemias and lymphomas.

    (MIR16-1 wt Allele, NCI Thesaurus)


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