Library / English Dictionary

    ACUTE LEUKEMIA

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Rapidly progressing leukemiaplay

    Classified under:

    Nouns denoting stable states of affairs

    Hypernyms ("acute leukemia" is a kind of...):

    cancer of the blood; leucaemia; leukaemia; leukemia (malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer)

    Hyponyms (each of the following is a kind of "acute leukemia"):

    acute lymphoblastic leukemia; acute lymphocytic leukemia (acute leukemia characterized by proliferation of immature lymphoblast-like cells in bone marrow, lymph nodes, spleen, and blood; most common in children)

    acute myelocytic leukemia; acute myeloid leukemia (acute leukemia characterized by proliferation of granular leukocytes; most common in adolescents and young adults)

    Credits

     Context examples: 

    Several acute leukemias are associated with translocations of the gene.

    (MLL wt Allele, NCI Thesaurus)

    This rearrangement is associated with therapy-related acute leukemia.

    (MLL/MAML2 Fusion Gene, NCI Thesaurus)

    The prognosis is good and transformation to acute leukemia is rare.

    (Myelodysplastic Syndrome with Isolated del(5q), NCI Thesaurus/WHO)

    Patients present with a myeloproliferative neoplasm, acute myeloid leukemia, lymphoblastic lymphoma/leukemia of T or B-cell lineage, or acute leukemia of mixed phenotype.

    (Myeloid and Lymphoid Neoplasms with FGFR1 Rearrangement, NCI Thesaurus)

    There is an increased risk of acute leukemias in both children and adults with Down syndrome.

    (Myeloid Proliferations Related to Down Syndrome, NCI Thesaurus)

    A drug used to treat acute leukemia.

    (Oncovin, NCI Dictionary)

    Allelic variants of the MTHFR gene are associated with susceptibility to numerous disorders including acute leukemia, colon cancer, neural tube defects and occlusive vascular disease.

    (MTHFR wt Allele, NCI Thesaurus)

    This gene is involved in transcriptional regulation and aberrations in the gene are associated with acute leukemias due to chromosomal translocations.

    (MLLT6 Gene, NCI Thesaurus)

    Acute leukemias are associated with a translocation t(10;11)(p12;q23) involving this gene and the MLL gene.

    (MLLT10 wt Allele, NCI Thesaurus)

    The gene is involved in a translocation t(1;11)(q21;q23) with the MLL gene that is associated with acute leukemia.

    (MLLT11 wt Allele, NCI Thesaurus)


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