| Library / English Dictionary |
ACUTE LYMPHOBLASTIC LEUKEMIA
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Acute leukemia characterized by proliferation of immature lymphoblast-like cells in bone marrow, lymph nodes, spleen, and blood; most common in children
Synonyms:
acute lymphoblastic leukemia; acute lymphocytic leukemia
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("acute lymphoblastic leukemia" is a kind of...):
acute leukemia (rapidly progressing leukemia)
Context examples:
Alteration in the expression of this gene is associated with development of acute lymphoblastic leukemia, chronic myeloid leukemia and psoriasis.
(MIR203 wt Allele, NCI Thesaurus)
This gene is involved in transcriptional regulation and alterations in the gene are associated with acute lymphoblastic leukemia.
(MLL Gene, NCI Thesaurus)
The wild-type allele is expressed in oligodendroglial tumors and is involved in a chromosomal translocation t(14;21)(q11.2;q22), which is associated with T-cell acute lymphoblastic leukemia.
(OLIG2 wt Allele, NCI Thesaurus)
A chromosomal deletion in the pseudoautosomal region 1 of either chromosome X or Y causing fusion of this gene with the CRLF2 gene is associated with B-cell acute lymphoblastic leukemia.
(P2RY8 wt Allele, NCI Thesaurus)
This rearrangement is associated with Down syndrome-associated acute lymphoblastic leukemia.
(P2RY8/CRLF2 Fusion Gene, NCI Thesaurus)
A chromosomal translocation t(1;19)(q23;p13.3) of this gene and the TCF3 gene is associated with pre-B-cell acute lymphoblastic leukemia.
(PBX1 wt Allele, NCI Thesaurus)
This fusion is associated with T-cell acute lymphoblastic leukemia.
(NUP214/ABL1 Fusion Gene Variant 1, NCI Thesaurus)
A non-T, non-B, acute lymphoblastic leukemia in which the lymphoblasts are positive for the common acute lymphoblastic leukemia antigen (cALLa) occurring in children.
(Non-T Non-B cALLa Positive Childhood Acute Lymphoblastic Leukemia, NCI Thesaurus)
Expression of a fusion protein that results from the insertion mutation ins(5;11)(q31;q13q23), which involves the human genes MLL and AFF1 and is associated with acute lymphoblastic leukemia.
(MLL-AF4 Fusion Protein Expression, NCI Thesaurus)
This rearrangement may be associated with acute myeloid leukemia and acute lymphoblastic leukemia.
(MLL/CASC5 Fusion Gene, NCI Thesaurus)
