LHX4/IGHG1 Fusion Gene

A fusion gene that results from a chromosomal translocation t(1;14)(q25;q32) which places the LHX4 gene on the 5' side of the coding sequence for the IGHG1 gene. This rearrangement is associated with acute lymphoblastic leukemia. (NCI Thesaurus)

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LHX4 wt Allele

Human LHX4 wild-type allele is located in the vicinity of 1q25.2 and is approximately 45 kb in length. This allele, which encodes…

LHX4 Gene

This gene plays a role in both transcription and pituitary differentiation.

LHX3 wt Allele

Human LHX3 wild-type allele is located in the vicinity of 9q34.3 and is approximately 9 kb in length. This allele, which encodes…

LHX3 Gene

This gene encodes a transcription factor that plays a role in both pituitary development and motor neuron specification.

LHX2 wt Allele

Human LHX2 wild-type allele is located within 9q33-34.1 and is approximately 22 kb in length. This allele, which encodes the LIM/homeobox protein…

LHX2 Gene

This gene plays a role in transcriptional regulation and has been implicated in the control of differentiation. The gene is also postulated…