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Losoxantrone
Pronunciation
Definition 1
An anticancer drug that belongs to the family of drugs called antipyrazoles. (NCI Dictionary)
Definition 2
An anthrapyrazole-based antineoplastic antibiotic. Losoxantrone intercalates into DNA, induces single- and double-stranded DNA breaks and inhibits topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. Losoxantrone is less cardiotoxic than doxorubicin. (NCI Thesaurus)
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