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Malignant Lymphoma, Large Cell, Cleaved and Non-Cleaved
Antiquated term describing follicular (nodular) or diffuse non-Hodgkin's lymphomas that are composed of a mixture of large cells: large cleaved cells, with irregular nuclei without visible nucleoli; and large non-cleaved cells (centroblasts), having a rounder nucleus with two to three small, peripherally placed nucleoli and a small amount of basophilic cytoplasm. The follicular variants represent mature B-cell lymphomas, whereas the diffuse variants can be either mature B- or mature T-cell lymphomas. --2004 (NCI Thesaurus)
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