Medicine
A standardized survey developed and published by Raymond C. Rosen and colleagues in 1997 which is used to assess erectile function. This… »
The International Medical Terminology is a clinically validated standard terminology for the reporting of regulatory activities, originally based upon the Medical Dictionary… »
INFOODS was established in 1984 on the basis of the recommendations of an international group convened under the auspices of the United… »
A classification system established by adopting the original system proposed by Shimada with subsequent revisions. The INPC distinguishes favorable and unfavorable histology… »
A standard approach to aid in the stratification of neuroblastoma risk and disease evaluation. »
A classification system developed to establish a consensus approach for pretreatment risk stratification of neuroblastomas. »
A surgicopathological staging system for neuroblastoma, based on the Evans staging system. »
A system, commonly called the INR, established by the World Health Organization (WHO) and the International Committee on Thrombosis and Hemostasis for… »
A measure of the extrinsic pathway of coagulation. The International Normalized Ratio of Prothrombin Time (INR) is the ratio of a patient… »
A list of five factors that help doctors assess how a non-Hodgkins lymphoma patient might respond to a certain treatment or predict… »
A system for scoring myelodysplasia syndrome progression risk, based on a combination of: percentage of blast cells in the bone marrow, the… »
A screening tool used to screen for, diagnose, track, and manage the symptoms of benign prostatic hyperplasia. »
Provides a top level guide to the main databases that describe the proteomes of higher eukaryotic organisms. IPI effectively maintains a database… »
An internationally unique identifier for a data element. »
The International Society of Preventive Oncology (ISPO) is the forum of an international membership committed to the study of interactive etiologic factors… »
A method of staging myeloma published by the International Myeloma Working Group in 2003. »
A non-SI unit of energy defined by the Fifth International Conference on the Properties of Steam, London, 1956, as 1/860 x international… »
The International System of Units (Systeme International d'Unites, SI) is a decimal system of weights and measures derived from and extending the… »
The International Union Against Cancer (UICC) is the only global cancer organisation with members and activities covering all aspects of cancer… »
An organization of national chemistry societies. It acts as an authority in developing standards for the naming of the chemical elements and… »
A unit used to measure the activity of many vitamins, hormones, enzymes, and drugs. An International Unit is the amount of a… »
An arbitrary unit of measurement of the specific biological activity of vitamin A, defined by the International Conference for Unification of Formula… »
International units per day. »
Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit per one gram of substance. … »
International units per hour. »
An arbitrary unit of substance content expressed in international units of biological activity per one kilogram of mass of the system. It… »
A dose calculation unit equal to one international unit (an arbitrary unit of biological activity) of a product per one kilogram of… »
Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit per one liter of the system… »
Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit per one milligram of substance. … »
Unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit of alpha-Tocopherol per one milligram of… »
A unit of arbitrary substance concentration with biologic activity defined as the concentration of international unit(s) per milligram of creatinine. »
A unit of arbitrary substance concentration (biologic activity concentration) defined as the concentration of one international unit per one milliliter of system… »
International units per minute. »
International units per second. »
A dose calculation unit expressed as a number of arbitrary units of biological activity (International Units) of substance per square meter of… »
A worldwide, decentralized network of computer networks connecting individuals and organizations to information and electronic mail services. »
The entity that oversees global IP address allocation, root zone management for the Domain Name System (DNS), media types, and other Internet… »
Internet Electronic Communication »
Internet Mobile Technology (e.g. iphone, mobile websites, epocrates) »
An item located online that cannot be classified within a particular set of terms. »
For most kids and teens, technology is an important part of their lives. They browse the Web for information, use social… »
Internet Social Media (e.g. facebook, twitter, myspace) »
A general term for any neurons which are not motor or sensory. Interneuron may also refer to neurons whose axons remain within… »
A doctor who specializes in internal medicine. An internist works with adult patients to prevent, diagnose, and treat diseases without using… »
Médico que se especializa en medicina interna. Un internista trabaja con pacientes adultos para prevenir, diagnosticar y tratar las enfermedades sin usar… »
Either of three arteries including the common interosseous artery which arises from the ulnar artery and bifurcates into the anterior and posterior… »
One of two deep veins (anterior or posterior) that run parallel to their corresponding artery in the forearm to drain the wrist… »
A cavity within the subarachnoid space between the two temporal lobes and in front of the pons. »
A short or long-term association between two or more people, including kinship relations, romantic, business, and social interactions. »
Hinge joints between the phalanges of the hand or foot. »
A ginglymoid (hinge) synovial joint within the first digit of the hand or foot connecting the proximal and distal phalanges. »
A ginglymoid (hinge) synovial joint between the phalanges of the second digit of the hand or foot. »
A ginglymoid (hinge) synovial joint between the phalanges of the third digit of the hand or foot. »
A ginglymoid (hinge) synovial joint between the phalanges of the fourth digit of the hand or foot. »
A ginglymoid (hinge) synovial joint between the phalanges of the fifth digit of the hand or foot. »
The hinge synovial joints between the bones of the toes. »
The hinge synovial joints between the phalanges of the fingers. »
A condyloid synovial joint within the thumb connecting the proximal and distal phalanges. »
A cell in a resting state. Individual chromosomes are not visible. The cell performs all biochemical and physiologic functions and replication of… »
Interphase chromosomes are decondensed chromosomes that reside in the interphase nucleus in the form of chromatin. Two types of chromatin, euchromatin and… »
The interval between two successive cell divisions during which the chromosomes are not individually distinguishable. Interphase is considered the resting stage of… »
An electrocardiographic finding of a premature ventricular complex which occurs between two normal QRS complexes which have normal timing. »
The substitution of missing data with an estimated value that falls between known data points. »
An act or process of elucidation; explication, or explanation of the meaning of the event or thing via the assignment of objects… »
Someone who mediates between speakers of different languages. »
Psychotherapy of the Freudian school. In this form of psychotherapy, symbols from the patient's verbalizations, dreams, and interactions are interpreted for… »
A computer program developed by the European Bioinformatics Institute that scans an input protein sequence against a range of stored protein… »
The difference between the 3d and 1st quartiles is called the interquartile range and it is used as a measure of variability… »
A rare congenital cardiovascular disorder characterized by the presence of a gap between the ascending and descending portions of the thoracic… »
A device designed to stop the flow of current in a circuit. »
A time interval during which there is a temporary cessation of something. »
The time span of a disruption in an event. »
The unit of measure for the duration of an interruption in treatment. »
Intersectin-1 (1721 aa, ~195 kDa) is encoded by the human ITSN1 gene. This protein plays a role in the regulation of both… »
A junction where one street or road crosses another. »
A person (one of unisexual specimens) who is born with genitalia and/or secondary sexual characteristics of indeterminate sex, or which combine features… »
An interstitial cell is a cell that is part of the connective and soft tissues. »
A specialized cell found throughout the gastrointestinal tract. These cells are essential for normal gastrointestinal motility by functioning as the pacemaker cells… »
A non-neuronal cell that supports the pineal gland. It resembles an astrocyte and is found around blood vessels and among groups of… »
A hormone made in the pituitary gland. In females, it acts on the ovaries to make follicles release their eggs and to… »
Interstitial collagenase (469 aa, ~54 kDa) is encoded by the human MMP1 gene. This protein plays a role in collagenolysis. »
Inflammation of the urinary bladder wall leading to urinary frequency, urgency, and discomfort, pelvic pain, and pain during intercourse. Morphologically it is… »
A disease occurring chiefly in the connective-tissue framework of an organ. »
Pathologic accumulation of air in the interstitium of the lungs. It is caused by the rupture of alveoli and terminal bronchioles. It… »
Fluid found in the spaces around cells. It comes from substances that leak out of blood capillaries (the smallest type of blood… »
Photodynamic therapy used to treat deep-seated solid tumors. »
Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. The inflammation and scarring… »
A renal disorder characterized by inflammation and edema of the interstitial tissue of the kidney. »
Inflammation of interstitial lung tissue, usually associated with infection. »
A type of internal radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into a… »
Drug administration to or in the interstices of a tissue. »
The very narrow portion of the fallopian tube passing through the uterine wall into the uterine cavity. »
The region that circles the Earth, near the equator, where the trade winds of the Northern and Southern Hemispheres come together. … »
A data type comprised of a set of consecutive values of an ordered base data type. »
One of the nodes that lie along the course of a lymphatic vessel between a primary melanoma site and a recognized node… »
A data type comprised of a set of consecutive values of an ordered point in time date and time datatype. »
A data type comprised of a set of consecutive values of an ordered point in time date datatype. »
A data type comprised of a set of consecutive values of an ordered point in time integer datatype. »
A data type comprised of a set of consecutive values of an ordered base, which is an abstract generalization for all value… »
A scale that uses ordered numbers with a constant difference but with no natural zero and where difference makes sense but ratios… »
En el campo de la medicina, conjunto de valores que el médico utiliza para interpretar los resultados de las pruebas en un… »
En el campo de la medicina, un tratamiento o una acción que se realiza para prevenir o tratar una enfermedad, o para… »
Uso de la comunicación, medicamentos u otros tipos de tratamientos específicos para un individuo o grupo con el fin de mejorar la… »
Ayuda inmediata de corto plazo (conversación con un consejero profesional) para detener una situación emocional grave (por ejemplo, intento de suicidio o… »
An artifact resulting from the presence of another body structure between the target and the receiver. »
An artifact resulting from the presence of a foreign body between the target and the receiver. »
In medicine, a treatment or action taken to prevent or treat disease, or improve health in other ways. »
The Intervention Community Trial is a controlled study that involves modification of causal or conjectural causal factors in a population to test… »
The period of time during which an intervention continues. »
The group receiving the study agent that is being tested in a clinical trial or clinical study. »
An integer specifying the number of intervention groups. »
The trial design developed to compare treatment groups. »
An activity that produces an effect, or that is intended to alter the course of a disease in a patient or… »
A patient condition when action or ministration whose purpose is to improve health or to alter the course of a disease is… »
A pre-clinical or clinical study in human beings in which individuals are assigned by an investigator based on a protocol to receive… »
The kind of product or procedure studied in a trial. »
The branch of radiology concerned with the use of radiation to treat disease. »
Studies in which individuals are assigned by an investigator based on a protocol to receive specific interventions. Subjects may receive diagnostic, therapeutic… »
An action plan of a pre-clinical or clinical study in which individuals are assigned by an investigator based on a protocol to… »
Specifies whether persons who have not had the condition(s) being studied or otherwise related conditions or symptoms, as specified in the eligibility… »
A coded value specifying the method of assigning subjects to treatment or control groups. »
A coded value specifying the roles of individuals who are masked for single or double blind studies. »
A coded value specifying the type of masking used on a study protocol to ensure that the results are not biased by… »
A coded value specifying the temporal relationships of the control to the study intervention. »
A coded value specifying the kind of comparison or comparator against which the study treatment is evaluated. »
An integer specifying the number of intervention groups. »
A character string that provides the key details of the intervention. »
The wall that separates the left and right ventricles of the heart. »
Spongy discs located between the vertebrae of the spinal column; composed of the outer annulus fibrosus and inner nucleus pulposus. »
A conversation with an individual regarding his or her background and other personal and professional details, opinions on specific subjects posed by… »
The person who answers the questions during an interview. »
The person who manages an interview and asks the questions. »
Having to do with the intestines. »
Relacionado con los intestinos. »
A congenital malformation characterized by the absence of a normal opening in a part of the intestine. It can occur either in… »
Your small intestine is part of your digestive system. It is a long tube that connects your stomach to your large… »
A classification of inherited or acquired disorders of sugar metabolism. Deficiencies of lactase, maltase or sucrase-isomaltase usually occur irreversibly and independent of… »
A non-neoplastic or neoplastic disorder that affects the small or large intestine. »
A rare congenital abnormality characterized by the presence of a duplicated segment of the intestine. The duplicated segment is cystic. »
An abnormal communication between the small or large intestine and another organ or cavity. »
Bacteria and other organisms that live inside the intestines. They help digest food. Vitamins such as biotin and vitamin K are made… »
A usually indolent, extra-adrenal paraganglioma affecting the intestine. Patients may present with gastrointestinal hemorrhage. Unlike the conventional paragangliomas, this tumor has a… »
The intestine is the largest lymphoid tissue in the body. One striking feature of intestinal immunity is its ability to generate great… »
A precancerous neoplastic process that affects the small or large intestine. It is characterized by low or high grade dysplasia of… »
A congenital abnormality in which the intestine is abnormally rotated (twisted). It may result in intestinal obstruction. »
A morphologic finding indicating the replacement of epithelial tissue outside the intestines by intestinal-type epithelium. »
A morphologic finding indicating the replacement of part of the columnar epithelium by intestinal-type epithelium. »
A finding indicating the replacement of part of the esophageal mucosal epithelium by intestinal-type epithelium. »
A morphologic finding indicating the replacement of part of the gastric mucosal epithelium with intestinal-type epithelium. Using immunohistochemical staining, gastric intestinal… »
Bacteria and other organisms that live inside the intestines. They help digest food. Vitamins such as biotin and vitamin K are made… »
A necrotic process involving the intestinal wall. »
A benign or malignant neoplasm involving the small or large intestine. »
An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the small or large intestine. The mitotic count is… »
A neoplasm with neuroendocrine differentiation that arises from the small or large intestine. It includes well differentiated neuroendocrine tumors (low and… »
A well differentiated, low or intermediate grade tumor with neuroendocrine differentiation that arises from the small or large intestine. »
A well differentiated, low grade neuroendocrine tumor (carcinoid tumor) that arises from the small or large intestine. The mitotic count is… »
A well differentiated, intermediate grade tumor with neuroendocrine differentiation that arises from the small or large intestine. The mitotic count is… »
An intestinal obstruction occurs when food or stool cannot move through the intestines. The obstruction can be complete or partial. There are… »
A rupture in the wall of the small or large intestine due to traumatic or pathologic processes. »
Obstruction of the intestines that is functional, not mechanical. »
Leakage of contents from the intestinal stoma. »
A blockage of the intestinal stoma. »
An intestinal stoma complication characterized by protrusion of the stoma above the abdominal surface. »
A finding of blood leakage from the intestinal stoma. »
Fibrosis of the wall of a segment of the intestine that leads to intestinal lumen narrowing. »
An adenocarcinoma arising from epithelium which has undergone intestinal metaplasia. Representative examples include gastric, gallbladder, and ampulla of Vater intestinal type… »
Tiny hair-like projections that line the inside of the small intestine. They contain blood vessels and help absorb nutrients. »
A finger-like projection of the plasma membrane found in the epithelial cells lining the intestinal tract that increase the lumen surface… »
Twisting of a loop of bowel that results in intestinal obstruction. »
The tissue that forms the wall of the small and large intestine. It consists of mucosa, submucosa, muscular coat, and serosal… »
The long, tube-shaped organ in the abdomen that completes the process of digestion. The intestine has two parts, the small intestine and… »
Surgical removal of part or all of the intestine. »
Órgano largo con forma de tubo ubicado en el abdomen, en el que se completa el proceso de la digestión. El intestino… »
Órgano en forma de tubo largo que conecta el estómago con el intestino grueso. Mide casi 20 pies de largo y se… »
Órgano largo, con forma de tubo que se conecta con el intestino delgado por un extremo y con el ano por el… »
A pan alpha-v human monoclonal antibody that recognizes alpha-v beta-1, alpha-v beta-3, alpha-v beta-5, and alpha-v beta-6 integrins with antiangiogenic and antitumor… »
A condition of close feelings shared between two people. Intimacy includes emotional intimacy and physical intimacy. »
Pertaining to the inner layer of the blood vessels. »
A malignant neoplasm arising from the large blood vessels. It is characterized by the presence of tumor cells that grow within… »
La intimidación es cuando una persona o grupo intenta repetidamente lastimar a alguien que es más débil o que cree que es… »
An antineoplastic agent. »
An inability to absorb or metabolize certain substances in the normal way. »
Incapacidad de digerir o absorber lactosa, un tipo de azúcar que se encuentra en la leche y otros productos lácteos. »
Medicamento que se ha estudiado para el tratamiento de algunos tipos de cáncer. La intoplicina bloquea las topoisomerasas, que son enzimas que… »
A substance that has been studied in the treatment of some types of cancer. Intoplicine blocks certain enzymes needed for cell division… »
Enfermedad causada por la diseminación de bacterias y sus toxinas en el torrente sanguíneo. También se llama septicemia y toxemia. »
Enfermedad grave causada por la exposición a dosis alta de ciertos tipos de radiación, habitualmente durante un tiempo corto. Los síntomas de… »
An herb native to islands in the South Pacific. Substances taken from the root have been used in some cultures to relieve… »
The range of possible values for any measurable characteristic, physical or mental, of a human being, analyzed, examined, investigated, experimented upon, or… »
Within the abdomen. »
A hemangioma arising from organs within the abdominal cavity. »
Bleeding within the abdominal cavity. »
Any lymph node within the abdomen. »
A lymphangioma arising from the organs of the abdominal cavity. »
A benign or malignant extra-adrenal paraganglioma arising from the abdominal cavity. »
A medical device that increases myocardial oxygen perfusion while at the same time increasing cardiac output. »
Within an artery (blood vessel that carries blood from the heart to tissues and organs in the body). »
A type of radiation therapy used to treat liver cancer that is advanced or has come back. Tiny beads that hold the… »
An electrocardiographic finding of a delay in impulse propagation through the atria. This is characterized by broad P waves which are often… »
Administration of the drug within the abdominal cavity, typically as a loco-regional therapy for disease confined to the abdomen. »
Administration of the drug within the amnion. »
Interior de una arteria (vaso sanguíneo que lleva la sangre del corazón a los tejidos y órganos del cuerpo). »
Intraarterial drug injection or infusion is a method of delivering a drug directly into artery or arteries to localize its effect to… »
Administration of the drug within a joint. »
Administration within the biliary system for selective delivery of the agent to targeted hepatobiliary tissues and cell types, the goal of which… »
Administration of a drug within a bronchus or bronchi. The intrabronchial drug delivery can be used for both local and systemic drug… »
Administration of a drug within a bursal cavity. »
Administration of a substance by injection directly into the anterior chamber of the eye. »
A morphologic variant of fibroadenoma without clinical significance. It is characterized by distortion and compression of the ducts by proliferating stromal… »
Administration of a drug within the heart. Concept refers both to administration into myocardium and within a chamber of the heart. … »
The introduction of fluids and drugs directly into the carotid artery, the main artery in the neck that carries blood from the… »
The introduction of fluids and drugs directly into the carotid artery, the main artery in the neck that carries blood from the… »
Administration of a drug within a cartilage. »
Administration of a drug within the cauda equina. »
Administration of a drug within a pathologic cavity. »
Interior de una cavidad o espacio, como el abdomen, la pelvis o el pecho. »
Within a cavity or space, such as the abdomen, pelvis, or chest. »
A type of internal radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into a… »
Administration of a drug within any natural, non-pathologic cavity, such as that of cervix, uterus, or penis. »
Inside a cell. »
Any subcellular process that acts to positively regulate the catalytic activities that underlie intracellular signaling. »
Any subcellular process that acts to negatively regulate the catalytic activities that underlie intracellular signaling. »
A thin pliable sheet separating organelles from the protoplasm. »
The process whereby cellular proteins are positioned and sequestered in the correct cellular compartment for proper function. The process of moving… »
Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They… »
Any subcellular process that is initated by a chemical or mechanical stimulus and results in a specific cellular response. »
Any subcellular or molecular event, process, or condition involved in translocation of a biological macromolecule from one site or compartment to another,… »
Interior de la célula. »
Of, ocurring in, or situated within the cerebrum. »
A cystic meningioma that grows within the cerebral hemispheres. »
Administration of a drug within the cerebrum, directly into brain tissue, usually by injection or direct application. »
Retroviral-like intracisternal A particles. High copy number family of repeated elements in the mouse with a typical proviral organization. Expressed… »
The intracisternal route involves Administration of a drug directly into the cerebrospinal fluid of the brain ventricles. It could be performed by… »
Within the clavicles. »
Within the colon. »
Interior del colon. »
Administration of a drug within the eye cornea. »
Administration of a drug within a crown of tooth. »
A device for use within the coronary anatomy. »
Administration of a drug within the coronary arteries supplying blood to the tissues of the heart. »
Administration of a drug within the dilatable venous spaces of the cavernous tissue of the penis. »
Situated or occurring within the cranium; affecting or involving intracranial structures. »
A congenital or acquired aneurysm within the cranium. »
A term referring to the brain area that is supplied by both the right and the left internal carotid arteries and their… »
Arteries which have their origins within the intracranial cavity. »
A cavernous hemangioma arising from the brain and meninges. »
Colloid cysts i.e. cysts filled with gelatinous material, in the central nervous system often are found in the third ventricle. Due to… »
An extraskeletal myxoid chondrosarcoma arising from the structures within the cranium. »
A hemangioma arising from the brain and meninges. »
Bleeding within the cranium. »
A finding characterized by increased cerebrospinal fluid pressure within the skull. »
A multinodular intermediate fibrocytic neoplasm arising from the intracranial soft tissue or viscera. It is characterized by the presence of spindle-shaped… »
A non-neoplastic or neoplastic pathologic process affecting the leptomeninges of the brain. »
A rare benign adipose tissue neoplasm located in the intracranial region. It is a congenital hamartomatous malformation derived from the embryologic meninx… »
A malignant adipose tissue neoplasm of the intracranial region. »
A meningioma that arises within the cranial cavity. »
A myeloid sarcoma that affects the meninges or the cerebral hemispheres. »
A benign or malignant neoplasm that arises from or metastasizes to structures within the cranium. This includes meningeal and other tumors… »
The brain, intracranial portions of the cranial nerves, intracranial blood vessels, intracranial meninges and other surrounding and supporting structures contained with the… »
A central nervous system primitive neuroectodermal tumor arising from the brain. »
Administration of a drug within the skull. »
A tumor that occurs in the brain. »
Two groups of blood vessels, deep and superficial intracranial veins, that drain deoxygenated blood from the brain. »
Dentro de la piel. También se llama intradérmico. »
Within the skin. Also called intradermal. »
A carcinoma entirely confined to the ducts. While intraductal (or DCIS) carcinomas can arise at other sites, these terms are universally… »
An intraductal breast carcinoma characterized by a papillary growth within a large cystic duct. There is no evidence of invasion of the… »
A papillary epithelial neoplasm arising in a cystically dilated breast duct. »
A morphologic finding indicating the presence of fine granular yellowish-brownish pigment within the cytoplasm of the cells in a tissue sample. … »
Within the skin. Also called intracutaneous. »
A nevus characterized by the proliferation of nevus cells in the dermis without involvement of the dermal-epidermal junction. »
Intradermal injection is a method of drug administration within the substance of the skin, particularly the dermis. »
Dentro de la piel. También se llama intracutáneo. »
Administration of a drug within a fibrocartilaginous intervertebral disc. »
A breast carcinoma characterized by the presence of a ductal carcinoma in situ component and an in situ or invasive lobular carcinomatous… »
A neoplastic process characterized by the proliferation of spindle to cuboidal myoepithelial cells within small breast ducts. »
A benign or malignant epithelial neoplasm that arises anywhere in the ductal system of the breast. This category includes intraductal papilloma,… »
A benign (not cancer), wart-like growth in a milk duct of the breast. It is usually found close to the nipple and… »
A benign breast neoplasm characterized by the proliferation of multiple papillomas within the lumen of the ducts. »
A noninvasive condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not spread… »
A ductal carcinoma in situ of the breast characterized by the presence of a cribriform architectural pattern. »
An intraductal papillary carcinoma in which the neoplastic epithelial cells are arranged in micropapillary patterns. »
A ductal carcinoma in situ of the breast characterized by the presence of sheets of tumor cells without evidence of central necrosis… »
A breast adenocarcinoma characterized by the presence of an intraductal papillary carcinomatous component and an invasive carcinomatous component. »
A non-invasive, papillary epithelial neoplasm that arises from the epithelium of the intrahepatic or extrahepatic bile ducts. »
A non-invasive breast adenocarcinoma located in a distended duct. It is characterized by the presence of papillary structures with fibrovascular stalks. In… »
A benign or malignant papillary neoplasm that arises anywhere in the ductal system of the breast. It is characterized by fibrovascular… »
A benign (not cancer), wart-like growth in a milk duct of the breast. It is usually found close to the nipple and… »
A neoplastic process characterized by the presence of multiple intraductal papillomas. »
A group of non-invasive epithelial proliferations that occur in the ductal system of the breast. The vast majority of cases arise… »
Administration of a drug within the duct of a gland. »
Administration of a drug within the duodenum. »
A neoplasm that occurs within the spinal canal in the space between the spinal cord and the dura mater. Representative examples… »
An area within the dura sheath but outside of the spinal cord. »
Administration of a drug within or beneath the dura mater. »
A rare cutaneous lesion presenting as a scaly verrucous plaque. Morphologically, the plaque contains nests of basaloid cells. »
Administration of a drug within the superficial epithelial layer of the skin. »
Interior de una capa de las células que forman la superficie o recubrimiento de un órgano. »
Within the layer of cells that form the surface or lining of an organ. »
A precancerous neoplastic process that affects the squamous, glandular, or transitional cell epithelium without evidence of invasion. According to the degree of… »
Glandular intraepithelial neoplasia arising in Barrett esophagus. »
A focal, non-invasive epithelial lesion composed of cells with atypical cytology and/or organization and risk of progressing to malignancy. Biological proof that… »
Administration of a drug within the cellular avascular layer covering internal and external surfaces of the body, its parts, organs, and… »
A mature T lymphocyte that migrates into epithelial tissue and contributes to the local and the systemic immune response. »
A mature T lymphocyte, found in the intestinal lining that differentiates from its precursor outside the thymus, most likely in an area… »
A method for monitoring the pH in the distal esophagus for the detection of acid reflux and the diagnosis of gastroesophageal reflux… »
Administration of a drug within the esophagus. »
Interior de la columna vertebral (espina dorsal). »
Administration of a medicinal product into an ovarian follicle. »
Administration of a drug within the stomach, e.g. via gavage or via gastrostomy. »
Administration of a drug within the gingivae. »
Within the liver. »
A bile duct that passes through and drains bile from the liver. »
A rare adenoma that arises from the intrahepatic biliary tree. »
A neoplastic, non-invasive lesion that affects the intrahepatic bile duct epithelium. It is characterized by the presence of atypical epithelial cells… »
A rare cancer that forms in the bile ducts inside the liver. A bile duct is a tube that carries bile (fluid… »
A clinical finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification… »
A pathologic finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification… »
A pathologic finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification… »
A pathologic finding about one or more characteristics of intrahepatic bile duct cancer, following the rules of the TNM AJCC v7 classification… »
Intrahepatic bile duct cancer with solitary tumor with vascular invasion or multiple tumors, with or without vascular invasion. »
Epithelium composed of one or more layers of glandular epithelial cells and a basement membrane lining the lumen of the intrahepatic bile… »
An adenoma that arises from the intrahepatic bile ducts and it is characterized by the presence of microcystic changes. »
A mucinous cystic neoplasm that arises from the intrahepatic bile ducts. »
A mucinous cystic neoplasm that arises from the intrahepatic bile ducts and it is associated with an invasive carcinomatous component. »
A non-invasive, papillary epithelial neoplasm that arises from the epithelium of the intrahepatic bile ducts. »
A papillary epithelial neoplasm that arises from the epithelium of the intrahepatic bile ducts and it is associated with an invasive carcinomatous… »
A congenital disorder characterized by blockage or absence of the intrahepatic bile ducts. »
A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant… »
Impairment of the bile flow caused by obstruction within the liver. »
The delivery of anticancer drugs directly to the blood vessels of the liver. »
Administration of a fluid form of the drug via a blood vessel into the liver over the sustained period of time. … »
An intrahepatic bile duct that is grossly visible and has a wall that is composed of fibrous tissue. »
The section of the left hepatic duct located in the liver. »
The section of the right hepatic duct located in the liver. »
Intrahepatic route of drug administration is a method of drug delivery within the liver, predominantly via hepatic vein or artery. Regimen might… »
Interior del hígado. »
Administration of a drug within the distal portion of the small intestine, from the jejunum to the cecum. »
Administration into the jejunum. »
Occuring within a single lab. »
Any one of the many cell groups located in the internal medullary lamina of the thalamus. »
Within an area of cancer, for example, within a tumor in the skin. »
En el interior de un área de cáncer; por ejemplo, en el interior de un tumor de la piel. »
Administration of a drug within or introduced directly into a localized lesion. Method allows to achieve high concentration of the agent in… »
A nephrogenic rest found within the renal lobe. »
A procedure in which a plastic or metal tube is inserted through the mouth into the esophagus (the tube that carries food… »
Administration of a drug within the cavity or channel of a tubular structure or tubular organ. »
Administration of a drug within the lymphatic system: into the lymph nodes or/and the lymph vessels. »
Occurring in, or located within the spinal cord or the marrow space of a bone. »
Administration of a drug within the marrow cavity of a bone. The essential premise for intraosseous administration is a functioning medullary… »
The administration of a drug within meningeal membranes. »
A neoplastic lesion that shows morphologic evidence of invasion into the lamina propria or muscularis mucosa. There is no evidence of… »
Infiltration of malignant glandular epithelial cells into the lamina propria of the intestine of the mouse without involvement of the submucosa. … »
A morphologic finding indicating the presence of eosinophils within the mucosa. »
A morphologic finding indicating the presence of a neutrophilic infiltrate within the mucosa of a tissue sample. »
Research that takes place on the NCI campus. »
The DCEG Intramural Research Award (IRA) is a new competitive funding mechanism to encourage exciting interdisciplinary projects that are innovative and cross… »
The office that oversees research efforts which take place on the NIH campus. »
The Postdoctoral Intramural Research Awards Program provides new investigators with advanced training and an opportunity to conduct full-time research in a laboratory… »
Within or into muscle. Also called IM. »
Dentro del músculo o en el músculo. También se llama IM. »
A hemangioma arising from skeletal muscle. »
Injection into muscle. »
A benign tumor, composed of mature adipocytes, that arises within skeletal muscle fibers. »
A myxoma arising from muscle tissues. »
Intramuscular injection is a route of drug administration via injection into muscle tissue. Aqueous or oleaginous solutions and emulsions or suspensions may… »
Surgical removal of part of the ethmoid bone, using an intra-nasl approach. »
An intranasal formulation of the synthetic cyclohexanone ketamine with analgesic and anesthetic activities. Although its mechanism of action is not well understood,… »
A benign, WHO grade I perineurioma that arises within the endoneurium. It is characterized by the formation of pseudo-onion bulbs by… »
Within the eyeball. »
Interior del ojo. »
Infection within the eye. »
A corrective lens that is designed to be implanted within the eye capsule to replace the natural lens. »
A lymphoma that arises within the eye. Signs and symptoms include decreased vision, uveitis, and vitreous floaters. »
A rare cancer of melanocytes (cells that produce the pigment melanin) found in the eye. Also called ocular melanoma. »
Cáncer poco frecuente de melanocitos (células que producen el pigmento melanina) que se encuentra en el ojo. También se llama melanoma… »
The fluid pressure within the eye. »
Increase of pressure of the intraocular fluid in the eye. »
Retinoblastoma restricted to local involvement. »
Administration of a drug within the eye. Intraocular drugs are almost always used for their local effects. »
A rare, unilateral, benign or malignant embryonic neoplasm typically presenting as a cilliary body mass during childhood. It is composed of medullary… »
Occurring during the course of a surgical procedure. »
Damage to an artery during a surgical procedure. »
Damage to the breast parenchyma during a surgical procedure. »
Damage to the heart during a surgical procedure. »
Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done,… »
Damage to the ear during a surgical procedure. »
Damage to an endocrine gland during a surgical procedure. »
Damage to any part of the gastrointestinal system during a surgical procedure. »
Damage to head and neck during a surgical procedure. »
Uncontrolled bleeding during a surgical procedure. »
Damage to the hepatic parenchyma and biliary tract during a surgical procedure. »
Damage to any part of the musculoskeletal system during a surgical procedure. »
Damage to any part of the nervous system during a surgical procedure. »
Damage to the eye during a surgical procedure. »
Radiation treatment aimed directly at a tumor during surgery. Also called IORT. »
Damage to the kidney during a surgical procedure. »
Damage to the reproductive organs during a surgical procedure. »
Damage to the respiratory system during a surgical procedure. »
Damage to the skin during a surgical procedure. »
Damage to the spleen during a surgical procedure. »
A procedure that uses ultrasound (high-energy sound waves that are bounced off internal tissues and organs) during surgery. Sonograms (pictures made by… »
Damage to any part of the urinary system during a surgical procedure. »
Damage to a vein during a surgical procedure. »
Any device worn within the mouth that can be removed and is not primarily designed to replace teeth. »
A meningioma that affects the intraorbital structures. »
Administration of a drug within the ovary or ovaries. »
Administration into the palate. »
A horizontal groove on the surface of the parietal lobe extending backward from the postcentral sulcus forming the ascending, superior and inferior… »
The period of time during labor and delivery. »
The process that occurs during labor and delivery. »
Fetal death greater than or equal to 20 weeks of gestation during labor and Apgar scores of 0 at 1 minute, 5… »
Within the pelvis, the lower part of the abdomen between the hip bones. »
Interior de la pelvis, que está en la parte inferior del abdomen entre los huesos de las caderas. »
Administration of a drug within the pericardium. Intrapericardial application of therapeutic agents provides a strategy for site-specific treatment of heart or coronary… »
Within the peritoneal cavity (the area that contains the abdominal organs). Also called IP. »
Dentro de la cavidad peritoneal (el área que contiene los órganos abdominales). También se llama IP. »
A method of euthanization whereby a subject is anesthetized and barbiturate(s) are administered intraperitoneally to induce respiratory arrest. »
Treatment in which anticancer drugs are put directly into the abdominal cavity through a thin tube. »
A method of delivering fluids and drugs directly into the abdominal cavity through a thin tube. Also called peritoneal infusion. »
Treatment in which a radioactive liquid is put directly into the abdomen through a thin tube. »
Intraperitoneal drug administration is a method of drug delivery via injection or infusion of a substance into the peritoneum, where it is… »
A solution intended for administration into the intraperitoneal cavity. »
Within the pleural cavity. »
Interior de la cavidad pleural. »
Administration of a drug within the pleural cavity. The intrapleural drug administration usually results in both local and systemic drug action. … »
Administration of a drug within the prostate gland. »
A bronchial branch that is located within the lung tissue. »
Administration of a substance in the form gas, aerosol, emulsion, or liquid (during partial and tidal liquid ventilation), or fine powder into… »
The administration of a substance within the nasal or periorbital sinuses. »
Within the spine (backbone). »
A meningioma that arises from the spinal meninges. »
A primary or metastatic neoplasm that occurs within the spinal canal including the spinal cord and surrounding paraspinal spaces. »
The administration of a drug within the vertebral column. High therapeutic ratio is based on drug delivery directly to central nervous system… »
A taxonomic family of marine bacterium in the phylum Actinobacteria that includes the genera Knoellia, Ornithinimicrobium and Janibacter, among others. »
Injection of a medicinal product into the bone marrow of the sternum. »
The administration of a drug within the synovial cavity of a joint. »
Describe el espacio lleno de líquido entre las capas delgadas de tejidos que cubren el cerebro y la médula espinal. Se pueden… »
The administration of an agent within a tendon. The route is used for local therapy in various conditions of the tendinous or… »
The administration of a drug within the testicle. »
Describes the fluid-filled space between the thin layers of tissue that cover the brain and spinal cord. Drugs can be injected into… »
Treatment in which anticancer drugs are injected into the fluid-filled space between the thin layers of tissue that cover the brain and… »
Administration of drugs directly into spinal subarachnoid space in the cerebrospinal fluid, at any level of the cerebrospinal axis, including injection into… »
Describes the fluid-filled space between the thin layers of tissue that cover the brain and spinal cord. Drugs can be injected into… »
Within the thorax. »
Within the thoracic cavity. »
Any lymph node within the thoracic cavity. »
A benign or malignant intrathoracic sympathetic paraganglioma arising from paravertebral paraganglia. In functional tumors, the hypersecretion of catecholamines results in… »
A parathyroid gland embedded within the thyroid gland parenchyma. »
The administration of a drug within the tubules of an organ. »
Within a tumor. »
Interior de un tumor. »
The administration of a drug within or introduced directly into a tumor. Method allows to achieve high concentration of the agent in… »
Direct administration of a therapeutic agent into a malignant tumor. »
The administration of a drug directly into the tympanic cavity has high safety profile and allows delivering high concentrations of the agent… »
Administration of a drug directly into the urethra. »
Neoplastic changes in the urinary tract transitional cell epithelium, characterized by cytologic and architectural abnormalities involving part or the entire thickness of… »
Inside the uterus (the small, hollow, pear-shaped organ in a woman’s pelvis in which a fetus develops). »
The retrieval of blood sample from the umbilical cord while the fetus is in utero. »
A small, plastic T-shaped device that is placed inside the uterus (the small, hollow, pear-shaped organ in a woman’s pelvis in which… »
A solid intended for placement within the uterine cavity where active and/or inert ingredient(s) are released from an apparatus at a controlled… »
Death of a fetus after 10 weeks gestation. »
A fetus whose estimated weight is below the 10th percentile for its gestational age; however, many fetuses who meet this definition are… »
The administration of a drug within the uterus. »
Perteneciente o relativo al interior del útero (órgano pequeño, hueco y con forma de pera en la pelvis de la mujer… »
Having to do with the inside of the vagina (the birth canal). »
Relacionado con el interior de la vagina (vía del parto). »
Movimiento de una célula o una sustancia extraña a través de la pared de un vaso sanguíneo o linfático hacia el vaso… »
The movement of a cell or a foreign substance through the wall of a blood or lymph vessel into the vessel… »
A morphologic variant of angioleiomyoma characterized by the adherence of neoplastic smooth muscle cells to the walls of vascular channels. »
A rare extranodal B-cell non-Hodgkin lymphoma, characterized by the presence of lymphoma cells exclusively in the lumina of small vessels, particularly… »
Metastasis that involves transfer of malignant cells via the cardiovascular system from one organ or part to another that is not directly… »
A rare, rapid growing, non-encapsulated benign neoplasm that arises from the vessels. It is characterized by the presence of non-hyperchromatic spindle-shaped fibroblasts,… »
The administration of an agent within a vessel or vessels. »
An invasive procedure in which sound waves (called ultrasound) are bounced off of vascular tissues from within the vessel and the echoes… »
En una vena o adentro de esta. Intravenoso por lo general se refiere a la manera de administrar un medicamento u otra… »
Into or within a vein. Intravenous usually refers to a way of giving a drug or other substance through a needle or… »
A dosing unit equal to the amount of active ingredient(s) contained in an intravenous bag. »
A method of euthanization whereby a subject is anesthetized and barbiturate(s) are administered intravenously to induce respiratory arrest. »
A volume of drug intended to be administered into a vein at a relatively fast rate. The volume of drug and the… »
Treatment in which anticancer drugs are given through a needle or tube inserted into a vein. The anticancer drugs travel through the… »
The administration of a drug within or into a vein or veins over a sustained period of time. A slow, continuous drip… »
A person who injects recreational drugs. »
A method of putting fluids, including drugs, into the bloodstream. Also called infusion. »
Injection into a vein. »
A rare benign neoplasm characterized by the presence of smooth muscle cells growing within veins. »
A method of intravenous narcotic analgesic delivery that uses a pump or similar delivery system that allows the patient, or in the… »
A solution intended for intravenous administration simultaneously with an established compatible maintenance infusion drug by a mutual intravenous access. »
A structural device designed to hang an intravenous solution bag. »
A method of drug delivery in which a usually small volume of drug is administered rapidly into a vein. »
An x-ray image of the kidneys, ureters, and bladder. It is made after a substance that shows up on x-rays is injected… »
A procedure in which x-ray images of the kidneys, ureters, and bladder are taken at regular times after a substance that shows… »
Administration of a drug within or into a vein or veins. Introduction of the drug directly into venous circulation results in 100%… »
A solution composed of a homogenous liquid that contains active and/or inert ingredient(s) dissolved in a suitable solvent or mixture of mutually… »
Located within a ventricle of the brain or heart. »
An electrocardiographic assessment of the transmission of electrical impulses through the cardiac atria and ventricles. »
Bleeding into the brain's ventricles. »
Neoplasms located in the brain ventricles, including the two lateral, the third, and the fourth ventricle. Ventricular tumors may be primary (e.g.,… »
The delivery of a drug into a fluid-filled cavity within the heart or brain. »
The delivery of a drug into a fluid-filled cavity within the heart or brain. »
A meningioma that affects the ventricles of the brain. »
Administration of a drug directly into a cerebral ventricle, commonly using a reservoir. This allows a more even distribution of drug through… »
Within the bladder. »
Dentro de la vejiga. »
The administration of a drug within the urinary bladder. »
Treatment in which anticancer drugs are injected directly into the vitreous humor (gel-like fluid inside the eye). Intravitreal chemotherapy is used to… »
The administration of a drug within the vitreous body of the eye. »
Blood coagulation or clotting takes place in 3 essential phases. The first phase is the activation of a prothrombin activator… »
The duration of the QRS complex that is generated by the subject's own heart. »
The intrinsic muscles spanning the length of the tongue that move the tip of the tonge up and down. »
The intrinsic muscles spanning the width of the tongue that depress and flatten the tongue. »
Non-coding, intervening sequences of DNA that are transcribed, but are removed from within the primary gene transcript and rapidly degraded during maturation… »
A drug used to treat AIDS-related Kaposi sarcoma in certain patients, hairy cell leukemia, and melanoma that has been removed by… »
Medicamento que se usa para tratar el sarcoma de Kaposi relacionado con el sida en ciertos pacientes, la leucemia de células pilosas… »
Any intronic mutation that occurs at a distance up to 10 bases from the exon junction. »
Any mutation within an intron, including the sequences that comprise the intron boundary. »
Single Nucleotide Polymorphism in Intronic Sequences (Intronic SNP) consists of a variation at an appreciable frequency between individuals of a single interbreeding… »
An unpleasant memory or idea that occurs often in a person’s everyday thoughts and keeps him or her from thinking about other… »
This gene may play a role in the transcriptional regulation that modulates chondrogenesis. »
Human INTS6 wild-type allele is located within 13q14.12-q14.2 and is approximately 92 kb in length. This allele, which encodes integrator complex subunit… »
Procedimiento mediante el cual se coloca un tubo plástico o metálico por la boca hacia el esófago (el tubo que lleva alimentos… »
The insertion of a cannula or tube into a hollow body organ. »
A general term for a group of culturally similar indigenous peoples inhabiting the Arctic regions of Canada, Greenland, Russia and the United… »
A naturally occurring, indigestible and non-absorbable oligosaccharide produced by certain plants with prebiotic and potential anticancer activity. Inulin stimulates the growth of… »
The rate at which inulin is removed or cleared from the whole or part of the body. »
Sustancia que se usa para mejorar la salud del aparato digestivo y los huesos, y que está en estudio para la prevención… »
Las inundaciones son comunes en Estados Unidos. El tiempo caracterizado por lluvias fuertes, tormentas o huracanes puede causar inundaciones. Las inundaciones también… »
A chromosomal inversion that involves chromosome 16. It is associated with the development of acute myeloid leukemia CBFB-MYH11, acute myelomonocytic leukemia with… »
Not valid data. »
Issue associated with the inaccuracy of a device designed to respond to an input (such as temperature, illumination, motion) to transmit a… »
A morphologic finding indicating the presence of a malignant cellular infiltrate invading the muscularis mucosa. »
Invasive carcinoma is the penetration of malignant epithelial cells (that demonstrates unequivocal glandular proliferation) through the basement membrane into the surrounding stroma… »
An invasive breast adenocarcinoma with cytological and immunophenotypic characteristics of apocrine differentiation in more than 90 percent of the malignant cells. … »
Cancer that has spread from where it began in the breast to surrounding normal tissue. The most common type of invasive breast… »
A carcinoma that infiltrates the breast parenchyma. The vast majority are adenocarcinomas arising from the terminal ductal lobular unit (TDLU). … »
Cancer that has spread beyond the layer of tissue in which it developed and is growing into surrounding, healthy tissues. Also called… »
A carcinoma that is not confined to the epithelium, and has spread to the surrounding stroma. »
Obvious extension of glands, nests or single cells extensively into stroma, including with apparent widening of the stroma (eosinophilic collagenous tissue), potentially… »
Cancer that has spread from the surface of the cervix to tissue deeper in the cervix or to other parts of the… »
An invasive adenocarcinoma of the breast with a favorable clinical outcome, characterized by the presence of a sieve-like or cribriform infiltrating… »
An invasive ductal breast carcinoma associated with an invasive lobular carcinomatous component. »
An invasive ductal breast carcinoma associated with a lobular carcinomatous component. The lobular carcinomatous component may be in situ or invasive. … »
An invasive ductal breast carcinoma associated with an in situ lobular carcinomatous component. »
A breast carcinoma characterized by the presence of a predominant ductal carcinoma in situ component and a minor component of invasive… »
The most common type of invasive breast cancer. It begins in the lining of the milk ducts (thin tubes that carry milk… »
The most common type of invasive breast carcinoma, accounting for approximately 70% of breast carcinomas. The gross appearance is usually typical… »
A type of cancer that grows into the muscular wall of the uterus. It is formed after conception (fertilization of an egg… »
A lesion marked by a spread into healthy surrounding tissue. »
An infiltrating lobular adenocarcinoma. The malignant cells lack cohesion and are arranged individually or in a linear manner (Indian files), or… »
A breast carcinoma characterized by the presence of a predominant lobular carcinoma in situ component and a minor component of invasive… »
A grade I invasive lobular carcinoma of the breast, characterized by the presence of round groups of neoplastic cells. »
A grade II invasive lobular carcinoma of the breast, characterized by the presence of neoplastic cells with large and atypical nuclei. … »
An invasive lobular carcinoma characterized by the presence of malignant epithelial cells with large intracytoplasmic lumina that cause displacement of the nuclei… »
A grade I invasive lobular carcinoma of the breast, characterized by the presence of neoplastic cells that form trabeculae and groups infiltrating… »
An invasive lobular carcinoma of the breast, characterized by the presence of neoplastic cells forming small tubular structures. »
A type of invasive breast cancer that begins in the lobules (milk glands) of the breast and spreads to surrounding normal… »
Cancer that has spread beyond the layer of tissue in which it developed and is growing into surrounding, healthy tissues. »
A malignant thymoma that extends beyond the capsule and infiltrates the surrounding tissues. --2003 »
An invasive breast carcinoma characterized by the presence of clusters of malignant cells located within artifactual clear stromal spaces that resemble vascular… »
An invasive breast carcinoma containing both ductal and lobular carcinomatous components. »
Including solid and rosetting, with scant to moderate cytoplasm, nuclear features of NE carcinoma or with immunophenotypic documentation »
A ductal breast carcinoma which invades the breast parenchyma. It is characterized by the formation of papillary structures. »
A medical procedure that invades (enters) the body, usually by cutting or puncturing the skin or by inserting instruments into the… »
A carcinoma that is not confined to the prostatic epithelium but has spread to the surrounding stroma of the prostate gland. … »
A melanoma of the skin that is not confined to the dermal-epidermal junction, and has infiltrated the dermis. »
Invasive malignant epithelial neoplasm characterized by cells with scant cytoplasm and hyperchromatic nuclei, which may show molding and chromatin streaming around blood… »
A thymoma of any morphologic type that extends beyond the capsule and infiltrates the surrounding tissues. --2003 »
A list of goods and materials, or those goods and materials themselves, held available for use by a business. »
An inverse association has the same basic meaning of an association but is expressed in the opposite direction. »
An inverse role has the same basic meaning of a role entity but is expressed in the opposite direction. »
A structural change in genomic DNA where the 5' to 3' order of a nucleotide sequence is completely reversed to the 3'… »
An animal lacking a vertebral column. This group consists of 98% of all animal species. »
The science concerned with the origin, structure, development, growth, function, genetics, and reproduction of animals that have no spinal column. »
The systematic classification of invertebrates. »
Tissue and cells from the general category of the kingdom Animalia (multicellular animals) including those phyla whose members lack a notochord. … »
Terrestrial animals without back bones »
Animals without a backbone that live in the ocean »
A type of tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may occur in the nose… »
A benign neoplasm that arises from the ciliated respiratory mucosa that lines the nasal cavity or paranasal sinuses. It results from… »
A benign epithelial neoplasm characterized by an endophytic growth, papillary pattern, and proliferation of neoplastic squamous cells without morphologic evidence of… »
A benign papillary neoplasm composed of transitional cells and characterized by an endophytic growth pattern. »
An endophytic lesion in the urinary tract which shares several morphologic features with urothelial papilloma. This lesion may recur after complete… »
A radiation field that covers the anterior chest well in the shape of an inverted 'Y'. It includes the inguinal, femoral, pelvic,… »
An electrical device that converts direct current to alternating current. »
Expresión que se usa para describir el proceso por medio del cual los resultados de una investigación realizada en el laboratorio se… »
Persona que investiga en un ensayo o estudio clínico. »
Profesional de la salud que trabaja directamente con pacientes o usa datos de pacientes para realizar investigaciones sobre salud y enfermedad, y… »
La(s) persona(s) a cargo de un ensayo clínico o una subvención científica para investigación. El investigador principal prepara y lleva a cabo… »
The act or process of a systematic and thorough examination; research, study; the process of inquiring into or following up, intended to… »
The result of an examination or inquiry. »
Basic research to understand the mechanisms that cells use to avoid being killed by cytotoxic drugs. »
In clinical trials, refers to a drug (including a new drug, dose, combination, or route of administration) or procedure that has undergone… »
A substance that has been tested in a laboratory and has gotten approval from the U.S. Food and Drug Administration (FDA) to… »
Allows an investigational device to be used in a clinical study in order to collect safety and effectiveness data required to support… »
A substance that has been tested in a laboratory and has gotten approval from the U.S. Food and Drug Administration (FDA) to… »
The group in a clinical research study that receives the drug, vaccine, or other intervention being tested. Interventions may also include medical… »
A device that is the subject of clinical investigation or research to determine the safety or effectiveness of the device. Investigational devices… »
Stability data submitted to an investigational new animal drug file. »
A new drug or biological drug that is used in a clinical investigation. The term also includes a biological product that is… »
Stability data submitted to an investigational new human drug application. »
An indicator that can be set or unset in order to signal whether an agent possesses a New Investigational Drug status. … »
An entity, either biologic or otherwise, of interest in an investigation. »
A researcher in a clinical trial or clinical study. »
The characteristic that defines the responsibility of the investigator on a particular study. »
A sequence of characters used to identify, name, or characterize the study investigator. »
The literal identifier of an investigator. »
A textual description of the investigator's credentials including, but not limited to the degree(s), board certification(s), license(s), diploma, and other official and/or… »
A category used to describe the registration status of a clinical study investigator with the FDA. A physician must be registered an… »
A textual or multimedia form of the signed name or personal mark of the investigator who is responsible for completing a particular… »
A category used to describe the registration status of a clinical study investigator with the regulatory authority agency, such as the FDA,… »
A category used to describe the registration status of a clinical study investigator in a particular study. »
Research conceived and conducted by scientists in laboratories and clinics across the country and at NCI. »
A request (spoken or written) to participate, be present, or take part in something »
Involucrin (585 aa, ~68 kDa) is encoded by the human IVL gene. This protein plays a role in the keratinization of stratified… »
Acto que no se realiza por voluntad propia. En el cuerpo, las acciones involuntarias (como el rubor) se presentan en forma automática… »
An action that is not made by choice. In the body, involuntary actions (such as blushing) occur automatically, and cannot be controlled… »
Uncontrolled and purposeless movements. »
The part of the nervous system that controls muscles of internal organs (such as the heart, blood vessels, lungs, stomach, and intestines)… »
Specifies whether the margins of surgical resection are infiltrated by disease. »
To have a connection by participation or association or use; sharing in an activity or process. »
Procedimiento por el que se inyectan medicamentos, vitaminas, extractos de hierbas u otros líquidos en el cuerpo en un punto de acupuntura,… »
Procedimiento en el que se usa una computadora y un aparato explorador de tres dimensiones para inyectar medicamentos contra el cáncer en… »
Inyección en el músculo. »
IV. Inyección en una vena. »
Inyección de etanol (alcohol) que se administra a través de la piel, directamente en el tumor para destruir las células cancerosas. Se… »
A synthetic, aralkylguanidine analogue of the adrenergic neurotransmitter norepinephrine (NE) and adrenergic neuron blocking agent with potential diagnostic imaging or antineoplastic activity… »
A drug containing a form of radioactive iodine called I 123 that is used to detect certain types of tumors, including pheochromocytomas… »
A drug containing a form of radioactive iodine called I 131 that is used to find or treat certain types of tumors,… »
An iodine (I) 123 labeled aralkylguanidine norepinephrine analogue used as a diagnostic imaging tracer. Iobenguane, structurally related to norepinephrine, functioning as a… »
A radioconjugate composed of the positron-emitting radioisotope iodine I 124 labeled to iobenguane, the synthetic aralkylguanidine analogue of the neurotransmitter norepinephrine (NE),… »
An I 131 radioiodinated synthetic analogue of the neurotransmitter norepinephrine. Iobenguane localizes to adrenergic tissue and, in radioiodinated forms, may be used… »
A procedure used to find neuroendocrine tumors, such as neuroblastomas and pheochromocytomas. A small amount of a substance called radioactive iobenguane is… »
The sulfate salt form of iobenguane, an iodine-123 labeled aralkylguanidine norepinephrine analogue used as a diagnostic imaging tracer. Iobenguane is structurally related… »
The sulfate salt form of iobenguane, an iodine-131 labeled aralkylguanidine norepinephrine analogue used as a diagnostic imaging tracer. Iobenguane is structurally related… »
Medicamento que contiene una forma de yodo radiactivo que se llama I 123. Se usa para detectar ciertos tipos de tumores, como… »
Medicamento que contiene una forma de yodo radiactivo que se llama I 131. Este se usa para encontrar o tratar ciertos… »
A water-soluble, tri-iodinated, non-ionic monomeric benzoate derivative and contrast medium used in diagnostic radiography. Upon administration, iobitridol is distributed through the vascular… »
A salt or ester of mineral iodine. Iodide salts are mild reducing agents and many react with oxygen to give iodine. … »
A contrast agent containing an iodine-based dye used in many diagnostic imaging examinations, including computed tomography, angiography, and myelography. »
A synthetic radiopharmaceutical in which human serum albumin (HSA) is radiolabelled with iodine 131. Upon intravenous injection, iodine-131 human serum albumin… »
An element that is necessary for the body to make thyroid hormone. It is found in shellfish and iodized salt. »
A radioimmunoconjugate comprised of a recombinant scFv dimer diabody of a monoclonal antibody against human carcinoembryonic antigen (CEA) labeled with iodine I… »
A radiopharmaceutical containing the dopamine D2/D3 receptor agonist iodobenzamide (IBZM) labeled with the radionuclide iodine I 123 with dopamine receptor-binding and radioisotopic… »
A drug containing a form of radioactive iodine called I 123 that is used to detect certain types of tumors, including pheochromocytomas… »
A drug containing a form of radioactive iodine called I 123 that is used to detect certain types of tumors, including pheochromocytomas… »
A radioactive isotope of iodine, a nonmetallic element of the halogen group, with an atomic mass of 124 and a half-life of… »
A radioimmunoconjugate composed of the F(ab')2 fragment of human monoclonal antibody PGN650 against phosphatidylserine (PS) labeled with the radioisotope iodine I 124,… »
A radiopharmaceutical comprised of the thymidine analog, 5-iodo-2-deoxyuridine (idoxuridine), labeled with the positron emitter iodine I 124. After incorporation into tumor… »
A radioimmunoconjugate consisting of the iodine I 124-radiolabeled murine IgG1 monoclonal antibody (MoAb) 8H9 directed against the cell surface glycoprotein CD276 (4Ig-B7-H3)… »
A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with Iodine 124 (I-124). MoAb A33 recognizes A33 antigen, a 43 KDa… »
A phospholipid ether analog labeled with iodine I 124, with a potential imaging property upon positron emission tomography (PET). Upon administration, iodine… »
A small molecule radiopharmaceutical composed of the radioisotope iodine I 124 covalently attached to a proprietary alkylphospholipid ether (PLE) analogue, with potential… »
A diagnostic radiopharmaceutical comprised of iodo-azomycin galactopyranoside (IAZGP) labeled with the positron-emitting radioisotope iodine I 124 and used as an imaging… »
A radioconjugate containing the purine scaffold heat shock protein 90 (Hsp90) inhibitor PUH71 labeled with the radioisotope iodine I 124, with positron… »
A radioimmunoconjugate consisting of a murine IgG2a monoclonal antibody directed against the human epidermal growth factor receptor (EGFR) labeled with iodine I… »
An iodine 131 radioimmunoconjugate of a small immunoprotein (SIP), derived from the variable region fragment of human monoclonal antibody L19, that is… »
A radioactive substance being studied in the treatment of liver cancer. It is a form of poppy seed oil that contains iodine,… »
A radioactive substance being studied in the treatment of liver cancer. It is a form of poppy seed oil that contains iodine,… »
A drug containing a form of radioactive iodine called I 131 that is used to find or treat certain types of tumors,… »
A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic properties. Using… »
A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with iodine 131 (I-131), with radioimaging and radioimmunotherapeutic activities. Using… »
A radioimmunoconjugate consisting of the iodine 131-radiolabeled murine IgG1 monoclonal antibody 8H9 directed against the surface immunomodulatory glycoprotein 4Ig-B7-H3 with potential radioimaging… »
A substance being studied in the treatment of some types of leukemia and lymphoma. BC8 is a monoclonal antibody that binds to… »
A radioimmunoconjugate consisting of the humanized CH2 domain-deleted monoclonal antibody CC49 and iodine I 131 with antineoplastic activity. Monoclonal antibody CC49-deltaCH2 targets… »
A fully human monoclonal antibody (MoAb) against human A1 domain of tenascin-C, in small immunoprotein (SIP) format conjugated with iodine 131 with… »
A radioimmunoconjugate comprised of the chimeric monoclonal antibody G-250 conjugated with iodine I 131 with potential antineoplastic activity. The antibody moiety of… »
A radioimmunoconjugate of a mouse monoclonal antibody (MoAb) J591 labeled with Iodine 131 (I-131). MoAb muJ591 recognizes the extracellular domain of the… »
An iodine 131 labeled radioimmunoconjugate of monoclonal antibody (MOAB) TNT-1/B with radioimaging and antineoplastic properties. MOAB TNT-1/B was developed for radioimmunotherapy of… »
A phospholipid ether analog labeled with iodine I 131, with potential radiotherapeutic and radioimaging potential upon positron emission tomography (PET). Upon administration,… »
A small-molecule radiopharmaceutical consisting of the beta-emitting radioisotope iodine I 131 attached to a phospholipid ether (PLE) analogue, comprised of a linear… »
A radioimmunoconjugate comprised of rituximab, a recombinant chimeric monoclonal antibody directed against the CD20 antigen, and labeled with iodine I 131 with… »
An iodine 131 (I 131) radioconjugate of the synthetic chlorotoxin (CTX) TM-601 with potential antiangiogenic and antineoplastic activities. CTX is a 36… »
A drug used with another drug to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment… »
A radioiodine-labeled cholesterol analogue with radioisotopic activity. Iodine 131-I-6-beta-iodomethyl-19-norcholesterol accumulates in tissues where steroid hormones are produced, including the adrenal cortex and,… »
A radioactive substance being studied in the treatment of liver cancer. It is a form of poppy seed oil that contains iodine,… »
A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and monovalent for histamine-succinyl-glycine (HSG) peptide-hapten radiolabeled with iodine I… »
A radioactive substance being studied in the treatment of liver cancer. It is a form of poppy seed oil that contains iodine,… »
A drug containing a form of radioactive iodine called I 131 that is used to find or treat certain types of tumors,… »
A substance being studied in the treatment of some types of leukemia and lymphoma. BC8 is a monoclonal antibody that binds to… »
A drug used with another drug to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment… »
A radioactive isotope of iodine, a nonmetallic element of the halogen group with an atomic mass of 123 and a half-life of… »
A radiopharmaceutical containing the serotonin transporter (SERT) ligand ADAM [2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine] labeled with the radioisotope iodine I 123, with SERT-binding and radioisotope… »
An iodine I-123 conjugate of metomidate (MTO) with potential application in adrenal imaging. Metomidate is a potent and selective inhibitor of the… »
An iodine 123-radiolabeled small molecule that exhibits high affinity for prostate-specific membrane antigen (PSMA) with potential use in molecular imaging. 123-I-MIP-1095, a… »
A radioconjugate containing the nucleoside analog 2'-fluoro-2'-deoxy-1beta-D-arabinofuranosyl-5-iodouracil (FIAU) labeled with the radioisotope iodine I 124 with positron-emitting activity. Chemotherapeutic agents such as… »
A radioimmunoconjugate comprised of the chimeric monoclonal antibody G250 conjugated with the positron emitter iodine I 124. The antibody moiety of iodine… »
A radioactive isotope of iodine, a nonmetallic element of the halogen group. With a half-life of 60 days, iodine 125 occurs… »
A radioactive isotope of iodine with an atomic mass of 131, a half life of eight days, and potential antineoplastic activity. Selectively… »
A microscopy staining method that utilizes Iodine, an element belonging to the halogen group, which specifically stains polysaccharides such as cellulose, chitin,… »
A finding indicating a deficiency or excess in biological absorption or assimilation of iodine. »
A tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging. When administered in vivo, iodipamide is removed from the… »
The meglumine salt form of iodipamide, a tri-iodinated benzoate derivative and an ionic dimeric contrast agent used in diagnostic imaging. When administered… »
A form of poppy seed oil that contains iodine. Iodized oil is given by injection and builds up in the blood and… »
Sustancia en estudio para el tratamiento del cáncer y la amiloidosis sistémica primaria (enfermedad en que las proteínas se depositan en órganos… »
A substance that is being studied as a treatment for cancer and for primary systemic amyloidosis (a disease in which proteins are… »
An iodine 131-radiolabeled small-molecule benzamide compound with potential antineoplastic activity. The benzamide moiety of 131-I-MIP-1145 binds to melanin, selectively delivering a cyotoxic… »
An iodine 123-radiolabeled small molecule that exhibits high affinity for prostate-specific membrane antigen (PSMA) with potential use in molecular imaging. Iofolastat I123,… »
An X-ray contrast medium containing iohexol in various concentrations, from 140 to 350 milligrams of iodine per milliliter. »
A measurement of the volume of serum or plasma that would be cleared of Iohexol through excretion for a specified unit of… »
An atom or a molecule that has a positive or negative electrical charge. Examples are sodium, potassium, calcium, chloride, and phosphate. These… »
Átomo o molécula que tiene una carga eléctrica positiva o negativa. El sodio, el potasio, el calcio, el cloro y el fosfato… »
A transmembrane pore that presents a hydrophilic channel for ions to cross a lipid bilayer down their electrochemical gradients. Some degree… »
Molecules transmitting signals into cells often act through receptors in the plasma membrane that stimulate production of second messengers. When activated by… »
Ion Channel Proteins typically aggregate in membrane-associated complexes forming pores whose activities regulate the movement of ions through cellular membranes to affect… »
Ion Channel Protein Genes encode Ion Channel Proteins that typically aggregate in membrane-associated complexes forming pores whose activities regulate the movement of… »
Endothelial cells (EC) form a multifunctional signal-transducing surface that performs different tasks dependent on its localization in the vessel tree. Arterial EC… »
Ion Exchanger Interaction consists of temporary non-covalent binding of a molecule through intermolecular physical forces of attraction with a membrane associated enzyme,… »
Ion Transport Alteration involves a change in the quality of the existing state of active uptake into, across or out of tissues… »
Any cellular process involved in the translocation of charged macromolecules, solutes and solvents into or out of a cell. »
Formation of a chemical bond following a transfer of electrons between two ions with opposite charges. »
A textile fiber dressing composed of ionic silver-impregnated sodium carboxymethylcellulose with potential wound-healing and antimicrobial activities. Ionic silver-impregnated sodium carboxymethylcellulose antimicrobial dressing… »
The weighted concentration of ions in solutions. »
Any process by which a neutral atom gains or loses electrons, thus acquiring a net charge, as the dissociation of a substance… »
A device that converts a sample into an ion stream. »
The determination of the amount of ionized calcium present in a sample. »
A type of radiation made (or given off ) by x-ray procedures, radioactive substances, rays that enter the Earth's atmosphere from outer… »
Medicamento antibiótico utilizado para tratar infecciones. »
Ion transfer of topical solution into the epidermis and mucous membranes of body by continuous direct current. Can be used for local… »
An organic iodine compound and used as a non-ionic water soluble radiographic contrast medium. Iopamidol blocks x-rays as they pass through the… »
Radiation treatment aimed directly at a tumor during surgery. Also called intraoperative radiation therapy. »
The rate at which iothalamate is removed or cleared from the whole or part of the body. »
The determination of the clearance of iothalamate and whose result is adjusted for body surface area. »
The meglumine salt form of iothalamate, an organic iodine compound and a radiographic contrast medium. Iothalamate meglumine blocks x-rays as they pass… »
The sodium salt form of iothalamate, an organic iodine compound and a radiographic contrast medium. Iothalamate sodium blocks x-rays as they pass… »
The sodium salt form of iothalamate, an organic iodine compound, labeled with iodine I-125 and used as a radiopharmaceutical. Iothalamate sodium I-125… »
An ionic tri-iodinated benzoate used as a contrast agent in diagnostic imaging. Like other organic iodine compounds, iothalamic acid blocks x-ray and… »
A procedure that uses ultrasound (high-energy sound waves that are bounced off internal tissues and organs) during surgery. Sonograms (pictures made by… »
The meglumine salt form of ioxaglate, an organic iodine compound and a radiographic contrast medium. Ioxaglate meglumine blocks x-rays as they pass… »
The sodium salt form of ioxaglate, an organic iodine compound and a radiographic contrast medium. Ioxaglate sodium blocks x-rays as they pass… »
An ionic tri-iodinated benzoate used as a contrast agent in diagnostic imaging. Like other organic iodine compounds, ioxaglic acid blocks x-rays and… »
Within the peritoneal cavity (the area that contains the abdominal organs). Also called intraperitoneal. »
Dentro de la cavidad peritoneal (el área que contiene los órganos abdominales). También se llama intraperitoneal. »
A substance found in many foods that come from plants, including corn, wheat, rice, and soybeans, and in large amounts in cereals… »
Sustancia que se encuentra en muchos alimentos que provienen de las plantas, como maíz, trigo, arroz y semillas de soja y, en… »
A regimen consisting of ifosfamide, cisplatin and doxorubicin, used in the neoadjuvant setting for the treatment of advanced-stage, childhood hepatoblastoma. »
A pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor… »
Inyección de etanol (alcohol) que se administra a través de la piel, directamente en el tumor para destruir las células cancerosas. Se… »
A novel proprietary small molecule, and a selective inhibitor of sonic hedgehog signaling pathway, with potential anti-tumor activity. The hedgehog signaling pathway… »
A drug used to treat melanoma that has spread to other parts of the body or that cannot be removed by… »
Medicamento que se usa para tratar el melanoma que se diseminó hasta otras partes del cuerpo o que no se puede extirpar… »
A natural toxic furan isolated from a fungus-infected sweet potato (Ipomoea batatas) with potential antineoplastic activity. Ipomeanol is activated by mixed… »
A synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic postganglionic effector cell… »
The bromide salt form of ipratropium, a synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine… »
A combination of albuterol and ipratropium with a bronchodilatory effect. Albuterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating the enzyme… »
A synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication… »
On the same side of the body as another structure or a given point. »
Relacionado con el mismo lado del cuerpo que otra estructura o un punto determinado. »
IQ domain-containing protein J (159 aa, ~18 kDa) is encoded by the human IQCJ gene. This protein may be involved in calmodulin… »
A type of smokeless tobacco that is made by mixing cured tobacco leaves with ashes from a certain type of fungus. It… »
Tipo de tabaco sin humo que se elabora mediante la mezcla de hojas curadas de tabaco y cenizas de determinado tipo de… »
Human IQCJ wild-type allele is located in the vicinity of 3q25.32 and is approximately 303 kb in length. This allele, which encodes… »
A fusion gene (~2.5 kb) that results from a read-through of 2 genes in the vicinity of 3q25.33 which fuses the IQCJ… »
A fusion protein (563 aa, ~62 kDa) encoded by the IQCJ/SCHIP1 fusion gene. It is comprised of the N-terminal half of the… »
Vigorous and healthy, but high incidence of physical abnormalities. Skulls of young fragile through weaning. High death rate from hemorrhage due to… »
This gene plays a role in signal transduction and the immune response. »
Human IRAK1 wild-type allele is located within Xq28 and is approximately 9 kb in length. This allele, which encodes interleukin-1 receptor-associated kinase… »
This gene is involved in the immune response and signal transduction. »
Human IRAK2 wild-type allele is located in the vicinity of 3p25.3 and is approximately 74 kb in length. This allele, which encodes… »
This gene is involved in signal transduction and the immune response. »
Human IRAK3 wild-type allele is located in the vicinity of 12q14.3 and is approximately 60 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and the immune response. »
Human IRAK4 wild-type allele is located in the vicinity of 12q12 and is approximately 29 kb in length. This allele, which encodes… »
A fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of… »
A group of scientists, doctors, clergy, and patient advocates that reviews and approves the detailed plan for every clinical trial. IRBs are… »
A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I… »
A country in western Europe, occupying five-sixths of the island of Ireland in the North Atlantic Ocean, west of Great Britain. … »
A drug that is used to treat certain types of non-small cell lung cancer and is being studied in the treatment of… »
Medicamento que se usa para el tratamiento de ciertos tipos de cánceres de pulmón de células no pequeñas y que se estudia… »
This gene plays a role in the transcriptional activation of target genes. It is also involved in promoting apoptosis. »
Human IRF1 wild-type allele is located within 5q23-q31 and is approximately 9 kb in length. This allele, which encodes interferon regulatory factor… »
This gene is involved in the repression of IRF1-activated transcription. It also plays a role in the transcriptional activation of target… »
Human IRF2 wild-type allele is located within 4q34.1-q35.1 and is approximately 87 kb in length. This allele, which encodes interferon regulatory factor… »
This gene plays a role in transcriptional repression. »
Human IRF2BP2 wild-type allele is located in the vicinity of 1q42.3 and is approximately 5 kb in length. This allele, which encodes… »
Human IRF3 wild-type allele is located within 19q13.3-q13.4 and is approximately 6 kb in length. This allele, which encodes interferon regulatory factor… »
This gene is involved in the regulation of B-cell differentiation and proliferation. It also plays a role in mediating the proliferation of… »
Human IRF4 wild-type allele is located within 6p25-p23 and is approximately 20 kb in length. This allele, which encodes interferon regulatory factor… »
Human IRF6 wild-type allele is located within 1q32.3-q41 and is approximately 18 kb in length. This allele, which encodes interferon regulatory factor… »
Human IRF8 wild-type allele is located in the vicinity of 16q24.1 and is approximately 24 kb in length. This allele, which encodes… »
Human IRF9 wild-type allele is located in the vicinity of 14q11.2 and is approximately 6 kb in length. This allele, which encodes… »
Human IRGM wild-type allele is located in the vicinity of 5q33.1 and is approximately 2 kb in length. This allele, which encodes… »
A radioactive isotope of iridium. Iridium-192 emits gamma rays and has a half-life of 74 days. A high dose rate of this… »
A group of disorders characterized by the presence of an abnormal inner layer of the cornea. This abnormality results in iris distortion,… »
Acute or chronic inflammation of the iris and ciliary body characterized by exudates into the anterior chamber, discoloration of the iris, and… »
The active ingredient in a drug used alone or with other drugs to treat colon cancer or rectal cancer that has spread… »
Ingrediente activo de un medicamento que se usa solo o con otros medicamentos para tratar el cáncer de colon o el cáncer… »
A drug used alone or with other drugs to treat colon cancer or rectal cancer that has spread to other parts of… »
A form of the anticancer drug irinotecan hydrochloride that is contained in very tiny, fat-like particles. Irinotecan hydrochloride liposome is used together… »
A chemo-immunotherapy regimen consisting of irinotecan and cetuximab used for the treatment of advanced stage colorectal cancer. »
A regimen consisting of irinotecan and cisplatin used for the treatment of extensive-stage small cell lung cancer. »
Microporous hydrospheres of polyvinylalcohol (PVA) impregnated with irinotecan with potential antineoplastic activity. In transarterial chemoembolization (TACE), irinotecan-eluting beads are administered into blood… »
An orally bioavailable combination tablet containing the semisynthetic camptothecin derivative irinotecan and the multidrug resistance (MDR) efflux pump P-glycoprotein (P-gp) inhibitor HM30181AK,… »
The colored tissue at the front of the eye that contains the pupil in the center. The iris helps control the size… »
Tejido de color en el frente del ojo que contiene la pupila en su centro. El iris ayuda a controlar el tamaño… »
Diseases, dysfunctions, or disorders of or located in the iris. »
A large iris (plant with sword-shaped leaves and erect stalks bearing flowers composed of three petals and three drooping sepals) with purple… »
Tumors of the iris characterized by increased pigmentation of melanocytes. Iris nevi are composed of proliferated melanocytes and are associated with neurofibromatosis… »
The Irish Setter is swift, with an acute sense of smell. It has a feathered, silky coat that comes in shades of… »
The Irish Terrier is a medium-sized, well-proportioned terrier with long whiskers, a bearded muzzle with powerful jaws, and bushy eyebrows. The ears… »
The Irish Water Spaniel is the largest of the spaniels with a solid brown (leaning to purple), crisp-textured, and curly coat. The… »
A massive, muscular dog, the Irish Wolfhound is one of the tallest breeds in the world. This gentle giant can reach the… »
Procedimiento para el que se usan ondas de radio y un imán muy potente conectado a una computadora para crear ilustraciones detalladas… »
Procedimiento para el que se usan ondas de radio y un imán potente unido a una computadora para producir imágenes detalladas de… »
Procedimiento para el que se usan ondas de radio y un imán potente unido a una computadora para producir imágenes detalladas de… »
Método no invasor de imaginología que proporciona información sobre la actividad celular (información metabólica). Se usa con las imágenes de resonancia magnética… »
Procedimiento para el que se usan ondas de radio y un imán muy potente conectado a una computadora para crear ilustraciones detalladas… »
A substance being studied in the treatment of some types of cancer. Irofulven attaches to the cell's DNA and may block cancer… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer. El irofulveno se une al ADN de la célula y puede… »
An important mineral the body needs to make hemoglobin, a substance in the blood that carries oxygen from the lungs to tissues… »
The capacity of iron-binding protein in serum (transferrin) to bind serum iron. »
Iron Chelation involves non-covalent coordination bonding between iron and an organic chemical, often as part of an enzyme or protein complex, as… »
A colloidal solution containing ferric oxyhydroxide complexed with polymerized dextran, used as a form of parenteral iron-replacement therapy. Upon administration and absorption,… »
A microscopy staining method that utilizes a mixture of iron and hematoxylin to visualize intracellular structures in a microscopic sample. In this… »
An intravenous colloidal solution containing trivalent iron (Fe3+) chelated to isomaltosides, used as iron replacement. The iron in iron isomaltoside 1000 is… »
The determination of the amount of iron present in a sample. »
A condition in which the body takes up and stores more iron than it needs. The extra iron is stored in the… »
An iron supplement consisting of an iron atom bound by a polysaccharide molecule. »
Iron stain is the classic method for demonstrating iron in tissues. Hemosiderin (storage iron granules) may be present in areas of old… »
A sterile aqueous complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Following intravenous administration, iron sucrose is dissociated by the… »
Iron Uptake Inhibition involves interference with, or restraint of, subcellular or molecular processes directly involved in the physical translocation from the extracellular… »
Anemia caused by low iron intake, inefficient iron absorption in the gastrointestinal tract, or chronic blood loss. »
Steroid sulfatase inhibitor BN 83495 selectively binds to and inhibits steroid sulfatase (STS), which may inhibit the production of locally active estrogens… »
Uso de radiación de alta energía proveniente de rayos X, rayos gamma, neutrones, protones y otras fuentes para destruir células cancerosas y… »
Radioterapia dirigida a la cabeza para reducir el riesgo de que el cáncer se disemine hasta el cerebro. »
Tipo de radioterapia que usa radiación gamma. La radiación gamma es un tipo de radiación de alta energía que es distinta de… »
Radioterapia dirigida al campo de manto, el bazo, los ganglios linfáticos de la parte superior del abdomen y los ganglios linfáticos del… »
Tipo de radioterapia que se administra solo a la parte de la mama que tiene cáncer. La irradiación parcial acelerada de la… »
Tipo de radioterapia que se administra solo a la parte de la mama que tiene cáncer. La irradiación parcial de la mama… »
Radioterapia dirigida a todo el cuerpo. Por lo general, es seguida por un trasplante de médula ósea o de células madre… »
Treated with radiation. »
A tissue volume which receives a dose that is considered significant in relation to healthy tissue tolerance. »
The use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation… »
The Irradiation Shared Resource provides Cancer Center investigators with support in the following areas: cell, tumor, specimen, animal irradiation for studies of… »
Tissue characterized by a thick, random arrangement of collagen and elastin fibers with very few cells. The majority of the cells are… »
Deviations from the normal process; e.g. delayed, difficult, profuse, scanty, unusual bleeding, etc. »
Not rhythmic pulse irregular in beat or accent. »
A change from the normal breathing pattern in an infant, child, or adult, in terms of the amplitude and frequency of inhalations… »
The irregular portion of the nephron. »
Que no se puede extirpar mediante cirugía. »
A substance that permanently blocks the action of an enzyme. In cancer treatment, irreversible enzyme inhibitors may block certain enzymes that cancer… »
Side effects that are caused by toxic substances or something harmful to the body and do not go away. »
En el campo de la medicina, limpieza de un órgano (como el estómago o el colon), una cavidad corporal o una herida… »
Procedimiento mediante el cual se enjuaga el colon de un paciente que se ha realizado una colostomía utilizando agua mediante un tubo… »
A solution or suspension used to bathe or flush open wounds or body cavities. »
In medicine, washing out an organ (such as the stomach or colon), a body cavity, or a wound by flushing it with… »
Administration of a drug by bathing or flushing open wounds, body cavities or surfaces. »
An abnormal responsiveness or morbid excitability of an organ, its part, or entire organism or its part to stimuli. »
A question about an individual's irritability at its worst. »
A disorder of the intestines commonly marked by abdominal pain, bloating, and changes in a person’s bowel habits. This may include… »
A disorder of the intestines commonly marked by abdominal pain, bloating, and changes in a person’s bowel habits. This may include… »
A question about whether an individual is or has been irritable with other people due to problems with their teeth, dentures or… »
An inflammatory skin condition caused by direct contact between the skin and an irritating substance. It is typically manifested by erythema, mild… »
A mild inflammatory tissue reaction; it can be caused by physical contact with an irritant or can be a local response to… »
This gene plays a role in signal transduction and carbohydrate metabolism. It is involved in mediation of the insulin response. »
Human IRS1 wild-type allele is located in the vicinity of 2q36 and is approximately 65 kb in length. This allele, which encodes… »
Human IRS2 wild-type allele is located in the vicinity of 13q34 and is approximately 33 kb in length. This allele, which encodes… »
Human IRS4 wild-type allele is located in the vicinity of 2q36 and is approximately 65 kb in length. This allele, which encodes… »
Tipo de medicamento que se usa para tratar la depresión y otros trastornos. El IRSN aumenta las concentraciones en el cerebro de… »
A cell-free mixture comprised of a variety of naturally-derived cytokines obtained from normal, unrelated donor lymphocytes with potential immunostimulatory activity. The cytokines… »
Boolean value indicating if this is the preferred taxon. »
Whether the sequence is a reference sequence. »
A relationship of specialization that states that a concept is a particular kind of another concept. This relationship relates concepts through logical… »
A rare nerve disorder that causes constant muscle activity that cannot be controlled, even during sleep. It often affects the muscles in… »
A water-soluble triazole prodrug with broad-spectrum antifungal activity. Isavuconazole is absorbed easily, given either orally or intravenously, and is hydrolyzed to its… »
A donor identification number that conforms to the ISBT-128 standard for traceability of human blood, blood products, tissues, and organs. »
Lack of blood supply to a part of the body. Ischemia may cause tissue damage due to the lack of oxygen and… »
An acute episode of focal cerebral, spinal, or retinal dysfunction caused by infarction of brain tissue. »
Cellular damage due to diminished oxygen supply to the tissues. The changes may be mild and associated with chronic inflammation, or severe… »
A renal disorder characterized by glomerular damage due to ischemia. It leads to progressive deterioration of renal function. »
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may… »
Myocardial tissue which exhibits characteristics of inadequate blood flow. »
Percent of the myocardial tissue estimated to exhibit characteristics of inadequate blood flow (ischemia). This is usually determined using a functional study… »
A condition in which there is a loss of blood flow to bone tissue, which causes the bone to die. It is… »
The bony prominence of the lower part of the ischium. »
A muscle of the perineum extending from the ischium to the corpus cavernosum penis in males and the clitoral glands in women… »
A tetrahedral region of adipose tissue located in the ischiorectal region with its base between the tuberosity of the ischium and the… »
A substance being studied in the treatment of oral mucositis (painful mouth sores) caused by cancer therapy and other conditions. Iseganan hydrochloride… »
A broad-spectrum aminoglycoside antibiotic structurally related to gentamicin and amikacin. Isepamicin has activity similar to amikacin but with better activity against bacterial… »
Medicamento contra el cáncer. Es un inhibidor mitótico. También se llama CI-980. »
Medicamento que se usa para tratar infecciones causadas por ciertos microorganismos. También está en estudio para el tratamiento del melanoma. Impide que… »
This gene is involved in both protein tagging and cell signaling. »
Human ISG15 wild-type allele is located in the vicinity of 1p36.33 and is approximately 1 kb in length. This allele, which encodes… »
A scoring system described by Dr. Ishak and colleagues that assesses the histopathologic degree of liver damage. »
No evidence of fibrosis. »
Minimal fibrosis in some portal areas. »
Minimal fibrosis in most portal areas. »
Fibrosis extends beyond the portal areas. Occasional portal to portal bridging fibrosis is present. »
Marked bridging fibrosis (portal to portal and porto-central) is present. »
Marked bridging fibrosis with formation of occasional hepatic nodules is present. »
Marked fibrosis with cirrhosis is present. »
A morphologic finding indicating the presence of foci of neuropil-like matrix that are immunostained positive for synaptophysin in infiltrating astrocytomas. »
An island in the Irish Sea, between Great Britain and Ireland. »
Islet amyloid polypeptide (89 aa, ~10 kDa) is encoded by the human IAPP gene. This protein plays a role in the regulation… »
A pancreatic cell that produces hormones (e.g., insulin and glucagon) that are secreted into the bloodstream. These hormones help control the level… »
The determination of the amount of islet cell 512 antibody present in a sample. »
The determination of the amount of islet cell 512 antigen present in a sample. »
A benign endocrine neoplasm arising from the pancreas. It is separated from the normal pancreatic tissues by a thin collagenous capsule. It… »
A rare cancer that forms in islet cells (hormone-making cells) of the pancreas. Islet cells make several different hormones that affect body… »
Islets are cells found in clusters throughout the pancreas. They are made up of several types of cells. One of these is… »
A tumor that forms in islet cells (hormone-making cells) of the pancreas. Islet cell tumors may be benign (not cancer) or malignant… »
The determination of the amount of islet neogenesis associated protein antibody present in a sample. »
The pancreatic tissue that contains the islets of Langerhans. It is responsible for the production and secretions of the pancreatic hormones. … »
A pancreatic cell that produces hormones (e.g., insulin and glucagon) that are secreted into the bloodstream. These hormones help control the level… »
A standard that specifies the nomenclature and shared semantics for a collection of data types commonly occurring in programming languages and software… »
An international standard that provides a set of data type definitions for representing and exchanging basic concepts that are commonly encountered in… »
A third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules… »
A quassinoid phytochemical isolated from the tropical plant Cedronia granatensis with potential antineoplastic and chemopreventive activities. »
A hydralazine and monoamine oxidase (MAO) inhibitor with antidepressant activity. Isocarboxazid blocks the breakdown (oxidative deamination) of biogenic amines by inhibiting MAO,… »
Either a point at which there is a maximum or minimum of a radiation dose or the center point of a radiation… »
Metacentric chromosomes produced during MEIOSIS or MITOSIS when the CENTROMERE splits transversely instead of longitudinally. The chromosomes produced by this abnormal division… »
Isocitrate dehydrogenase [NADP] cytoplasmic (414 aa, 47 kDa) is encoded by the human IDH1 gene. This protein plays a role the oxidation… »
Isocitrate dehydrogenase 2 (NADP+) mitochondrial protein (452 aa, ~51 kDa) is encoded by the human IDH2 gene. This protein plays a role… »
A radiation dose of equal intensity applied to more than one body area; of or relating to points or zones in a… »
A type of gel electrophoresis in which charged molecules travel through a pH gradient. The molecules will come to stop at… »
The pH at which a molecule in solution has no net charge and does not migrate in an electric field. »
A beta-adrenergic receptor agonist with bronchodilator activity. Isoetharine selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl… »
Sustancia semejante al estrógeno elaborada por algunas plantas, como la planta de la soja. Las isoflavonas de la soja están en estudio… »
An estrogen-like substance made by some plants, including the soy plant. Soy isoflavones are being studied in the prevention of cancer, hot… »
A fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, inhaled isoflurane,… »
Refers to variants of the same protein which can be separated on special conducting media using electrophoresis. The differences may arise from… »
An antibody that is reactive towards the A antigen present on the surface of some red blood cells. They are usually IgM… »
An antibody that is reactive towards the B antigen present on the surface of some red blood cells. They are usually IgM… »
Having the same intensity as another object. Used to describe the results of imaging tests, such as x-rays, MRIs, or CT… »
Que tiene la misma intensidad que otro objeto. Término que se usa para describir los resultados de las pruebas de imaginología, tales… »
An exercise that involves movement at a constant rate with a variable force throughout a specified range of motion. »
A specific individual microbe and its genetically identical progeny separated on a single occasion from a sample taken from a host or… »
A process that fills a dosage unit with a liquid, which is performed in a closed environment under sterile conditions and without… »
A process that fills a dosage unit with a powder, which is performed in a closed environment under sterile conditions and without… »
A procedure in which a catheter is placed into the artery that provides blood to the liver; another catheter is placed into… »
A procedure used to deliver anticancer drugs directly to an arm or leg but not to the rest of the body. The… »
A surgical procedure during which the circulation of blood to the lungs is separated from the circulation of blood through the rest… »
Neoplasm drug therapy involving an extracorporeal circuit with temporary exclusion of the tumor-bearing area from the general circulation during which high concentrations… »
A procedure in which a catheter is placed into the artery that provides blood to the liver. A second catheter is placed… »
A procedure used to deliver anticancer drugs directly to an arm or leg but not to the rest of the body. The… »
A procedure that may be used to deliver anticancer drugs directly to an arm or leg. The flow of blood to and… »
A surgical procedure during which the circulation of blood to the lungs is separated from the circulation of blood through the rest… »
The presence of single tumor cells or tiny clusters of tumor cells in a pathologic specimen. »
State of being separated from others. Isolation is sometimes used to prevent disease from spreading. »
Any material or structure designed to limit the interaction between two components. »
One of nine essential amino acids in humans (present in dietary proteins), Isoleucine has diverse physiological functions, such as assisting wound healing,… »
The determination of the amount of the isoleucine in a sample. »
One of two or more compounds that have the same chemical formula but different arrangements of the atoms within the molecules and… »
An enzyme that transfers functional groups to catalyze the geometric or structural rearrangement of atoms within a given molecule to form an… »
Isomerase Genes encode enzymes (Isomerases) that catalyze spatial or structural changes within a molecule by rearrangement or transfer of specific atoms or… »
Uno de dos o más compuestos que tienen la misma fórmula química pero diferente disposición de los átomos dentro de las moléculas… »
A combination preparation containing isometheptane, dichloralphenazone and acetaminophen with analgesic activity. Isometheptene is an indirect-acting sympathomimetic agent with vasoconstricting activity, thereby reducing… »
An exercise that is performed by exerting force against an immovable object or by holding an object in a static position. … »
A synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action is still unclear, isoniazid appears to block… »
An organic, branched-chain alkane with five carbon atoms. »
An unsaturated pentahydrocarbon, Isoprene is found in certain plants or obtained by distillation of caoutchouc or gutta-percha. In plants, it is elementary… »
Isoprenylation Inhibition involves interference with, or restraint of, enzymatic activities involved in covalent addition of prenyl and multiprenyl residues to polypeptide chains… »
The covalent addition of prenyl and multiprenyl residues to a macromolecule. »
An isomer of propyl alcohol with antibacterial properties. Although the exact mechanism of isopropanol's disinfecting action is not known, it might kill… »
A group of compounds similar to prostaglandins with immunomodulating activity. Isoprostanes are formed through free radical catalyzing non-enzymatic reactions involving peroxidation of… »
A synthetic catechol compound and potent beta adrenergic agonist with peripheral vasodilator, bronchodilator, and cardiac stimulating properties. Isoproterenol exerts its effect on… »
The hydrochloride salt form of isoproterenol, a synthetic catechol compound and potent beta adrenergic agonist with peripheral vasodilator, bronchodilator, and cardiac stimulating… »
The sulfate salt form of isoproterenol, a beta-adrenergic receptor agonist with bronchodilator activity. Isoproterenol binds to beta-2 adrenergic receptors in bronchial smooth… »
An electrocardiographic finding of a type of atrioventricular dissociation characterized by the atria (P waves) and ventricles (QRS complexes) beating at similar… »
An organic nitrate with vasodilator activity. Isosorbide relaxes vascular smooth muscle by formation of the free radical nitric oxide (NO), which is… »