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Malignant peripheral nerve sheath tumor
Pronunciation
Definition 1
A type of soft tissue sarcoma that develops in cells that form a protective sheath (covering) around peripheral nerves, which are nerves that are outside of the central nervous system (brain and spinal cord). Also called MPNST. (NCI Dictionary)
Definition 2
An uncommon, highly aggressive malignant tumor, arising from the peripheral nerves and affecting mostly adults in their third to sixth decades of life. It usually occurs in medium-sized and large nerves of the buttock, thigh, upper arm, or the paraspinal region. It may be associated with neurofibromatosis 1 (NF1). (NCI Thesaurus)
Definition 3
A malignant neoplasm, originating from the sheaths of the peripheral nerve. (NCI Thesaurus/CDISC)
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