Health / Medical Topics

    MLLT4 wt Allele

    Human MLLT4 wild-type allele is located in the vicinity of 6q27 and is approximately 145 kb in length. This allele, which encodes afadin protein, is involved in the mediation of cell to cell adhesion. The gene can be involved in a translocation with the MLL gene, t(6;11)(q27;q23), which is associated with some acute leukemias. (NCI Thesaurus)




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