Library / English Dictionary

    NEOMYCIN

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    An antibiotic obtained from an actinomycete and used (as a sulphate under the trade name Neobiotic) as an intestinal antiseptic in surgeryplay

    Synonyms:

    fradicin; Neobiotic; neomycin

    Classified under:

    Nouns denoting man-made objects

    Hypernyms ("neomycin" is a kind of...):

    antibiotic; antibiotic drug (a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections)

    antiseptic (a substance that destroys micro-organisms that carry disease without harming body tissues)

    Credits

     Context examples: 

    The sulfate salt form of framycetin, an aminoglycoside antibiotic isolated from Streptomyces lavendulae (decaris), mainly containing neomycin B, with broad-spectrum antibacterial activity.

    (Framycetin Sulfate, NCI Thesaurus)

    The NEO Gene confers resistance to the aminoglycoside antibiotic neomycin.

    (NEO Gene, NCI Thesaurus)

    A substance that works against many types of bacteria and includes streptomycin, gentamicin, and neomycin.

    (Aminoglycoside antibiotic, NCI Dictionary)

    A combination preparation containing the polypeptide antibiotic polymyxin b, the aminoglycoside antibiotic neomycin, the glucocorticoid hydrocortisone and, in some formulations, the antibiotic bacitracin zinc with antibacterial and anti-inflammatory activities.

    (Cortisporin Formulation, NCI Thesaurus)

    Half the participants in each group also received a five-day course of a broad-spectrum antibiotic regimen (consisting of neomycin, vancomycin, and metronidazole) by mouth before receiving the vaccine.

    (Disrupting the gut microbiome may affect some immune responses to flu vaccination, National Institutes of Health)

    A preparation of T lymphocytes harvested from a patient with cancer and transduced with the PG13/Lnc8 retroviral vector, a clone of the LN vector that encodes the neomycin phosphotransferase gene.

    (PG13/LNc8 Retroviral Transduced Cloned T-Cells, NCI Thesaurus)

    Polymyxin B, neomycin and bacitracin zinc exert antibacterial effects through a cationic detergent-like action on cell membranes, inhibition of protein synthesis, and inhibition of peptidoglycan synthesis, respectively.

    (Cortisporin Formulation, NCI Thesaurus)

    Neomycin is an antibiotic complex consisting of 3 components: the two isomeric components B and C are the active components, and neomycin A is the minor component.

    (Neomycin, NCI Thesaurus)

    One of the two major active isomeric components of the neomycin complex.

    (Neomycin C, NCI Thesaurus)

    Neomycin sulfate, an aminoglycoside antibiotic, irreversibly binds to the bacterial 30S ribosomal subunit, thereby preventing mRNA from binding to the 30S subunit, causes misreading and inhibits protein synthesis.

    (Neosporin Cream, NCI Thesaurus)


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