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Non-Receptor Tyrosine Kinase Gene
Originally identified in the Rous sarcoma virus src transforming gene, Non-Receptor Tyrosine Kinase Genes encode Protein Tyrosine Kinases, enzymes important in control of cell growth, proliferation, differentiation, and transformation that do not function as receptors, but catalyze tyrosine phosphorylation of proteins with ATP, or other nucleotides as phosphate donors. (NCI Thesaurus)
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Non-Receptor Protein Tyrosine Phosphatase Genes encode Non-Receptor Protein Tyrosine Phosphatases, one of the two main categories (soluble and transmembrane receptor) of enzymes…
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A non-radiological determination of disease progression based on symptoms or other findings.
Treatment not specified in a protocol.
