| Health / Medical Topics |
NUP214 wt Allele
Human NUP214 wild-type allele is located in the vicinity of 9q34.1 and is approximately 108 kb in length. This allele, which encodes nuclear pore complex protein Nup214, plays a role in the regulation of nucleocytoplasmic transport and receptor-mediated nuclear import. The 3 prime portion of the gene can form a fusion construct with the DEK gene on chromosome 6 in a t(6,9) translocation. The translocation is associated with acute myeloid leukemia and myelodysplastic syndrome. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene plays a critical role in nuclear transport and docking regulation. Alterations in the gene have been associated with several cancers…
Human NUP107 wild-type allele is located in the vicinity of 12q15 and is approximately 56 kb in length. This allele, which encodes…
This gene is involved in the assembly of the nuclear pore complex.
An Arctic territory in northern Canada created in 1999 and governed solely by the Inuit; includes the eastern part of what was…
A drug used to treat moderate to severe pain. It is also used as a sedative before surgery, to help with…
An irregularity in the number of chromosomes.
