| Health / Medical Topics |
Oncogene CSF1R
Human colony stimulating factor 1 receptor (CSF1R) gene, located at 5q33.2-q33.3, encodes macrophage colony stimulating factor I receptor protein. Mutations in this gene have been detected in both chronic myelomonocytic leukemia and type M4 acute myeloblastic leukemia. One out of fifty hematologically normal individuals exhibit a CSFR1 variant allele (Y969C) that may cause a predisposition to myeloid malignancy. (NCI Thesaurus)
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