Medicine
A methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus. Bioreduced mitomycin B generates oxygen radicals, alkylates DNA, and produces interstrand… »
A drug used to treat advanced cancer of the stomach and pancreas that has not gotten better with other treatment. It is… »
The type of cell division that allows a population of cells to increase its numbers or to maintain its numbers. The number… »
Proceso por el cual una sola célula parental se divide para producir dos células hijas. Cada célula hija recibe un conjunto completo… »
A tumor cell proliferation measurement represented by the number of cells in mitosis plus the number of cells in karyorrhexis per 5000… »
An anticancer drug used in treating adrenocortical cancer and ACTH-producing pituitary tumors (Cushing disease). »
Medicamento contra el cáncer que se utiliza para tratar el cáncer de la corteza suprarrenal y los tumores pituitarios productores de ACTH… »
A nucleotoxic with potential antineoplastic activity. The mechanism of action through which mitotenamine exerts its effect has yet to be fully… »
Having to do with the presence of dividing (proliferating) cells. Cancer tissue generally has more mitotic activity than normal tissues. »
Mitotic checkpoint serine/threonine-protein kinase BUB1 (1085 aa, ~122 kDa) is encoded by the human BUB1 gene. This protein is involved in both… »
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (1050 aa, ~120 kDa) is encoded by the human BUB1B gene. This protein is involved in… »
A biological process that occurs during mitosis to ensure proper chromosomal numbers in daughter cells. »
Condensed chromosomes observed during the M phase of the cell cycle. Individual chromosomes can be discerned and differentiated morphologically. »
The number of mitoses identified under the microscope in tumors. It is one of the parameters that determine the grade of… »
The process a cell goes through each time it divides. The mitotic cycle consists of a series of steps during which the… »
A class of compounds that modulate the activity of mitotic enzymes. Mitotic enzymes regulate various mitotic events including centrosome separation, mitotic spindle… »
The microscopic appearance of a cell undergoing mitosis. »
In a population of cells, the ratio of the number of cells undergoing mitosis (cell division) to the number of cells not… »
A type of drug that blocks cell growth by stopping mitosis (cell division). They are used to treat cancer. Also called antimitotic… »
A class of compounds that modulate the activity of mitotic kinesins. Mitotic kinesins or microtubule-associated proteins (MAPs) are ATP-powered proteins that convert… »
The failure of the chromosomes to disjoin and move to opposite poles during mitosis, by which could result in mosaic individual. … »
A measure of how fast cancer cells are dividing and growing. To find the mitotic rate, the number of cells dividing in… »
Any type of recombination occuring within somatic cells and involving possible exchange and frequent loss of segments of DNA by either homologous… »
The faithful segregation of genetic information requires highly orchestrated changes of chromosome structure during the mitotic cell cycle. The linkage between duplicated… »
Mitotic spindle assembly checkpoint protein MAD2A (205 aa, ~24 kDa) is encoded by the human MAD2L1 gene. This protein is involved in… »
One of the central features of mitotic cell division is the formation of the spindle that segregates chromosomes into each daughter… »
The mitotic/spindle checkpoint ensures that all replicated chromatids are properly connected to opposing spindle poles before separation (anaphase) can begin. The proteins… »
Medicamento que se usa para tratar el cáncer de próstata avanzado que no responde a las hormonas, también se usa en la… »
A drug used to treat advanced prostate cancer that does not respond to hormones, adult acute nonlymphocytic leukemia, and advanced or chronic… »
The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA… »
A regimen consisting of mitoxantrone and etoposide used for the treatment of adult acute myelogenous leukemia (AML). »
A prodrug of imidazotetrazine alkylating agent with antineoplastic property. Mitozolomide undergoes ring opening upon the nucleophilic attack at C-4 by an activated… »
A drug used to treat advanced cancer of the stomach and pancreas that has not gotten better with other treatment. It is… »
Medicamento que se usa para tratar el cáncer de estómago y el cáncer de páncreas avanzados que no mejoraron con otro… »
Dilation of the valve between the left atrium and the left ventricle of the heart by inflating a balloon. »
Dilation of the valve between the left atrium and the left ventricle of the heart by use of a surgeon's finger… »
Narrowing of the left atrioventricular mitral orifice. »
A dual-flap valve of the heart that regulates the flow of blood between the left atrium and the left ventricle of the… »
A congenital heart defect characterized by the complete atresia of the mitral valve. »
A heart disorder characterized by a defect in mitral valve structure or function. »
Dysfunction of the mitral valve characterized by incomplete valve closure. »
A fairly common and often benign valvular heart disorder characterized by redundancy or hooding of mitral valve leaflets so that they prolapse… »
The backward flow of blood from the left ventricle into the left atrium, owing to insufficiency of the mitral valve; it may… »
Surgery performed for the purpose of repairing stenosis or regurgitation of the mitral valve. »
Surgery performed with the purpose of replacing a degenerated, calcified, malformed, dysfunctional, etc. mitral valve with bioprosthetic, homograft or autograft valve. … »
Medicamento que se usa para tratar algunos tipos de cáncer de testículo. Asimismo, se usa para tratar las cantidades anormalmente altas de… »
A microsomal triglyceride transfer protein inhibitor, approved in veterinary use for weight loss and reduction of hyperlipidemia in dogs. »
A genus of anaerobic, Gram negative, rod shaped bacterium assigned to the phylum Firmicutes and the family Veillonellaceae. »
A genus of anaerobic, Gram negative, rod shaped bacterium assigned to the phylum Firmicutes. This species is susceptible to Kanamycin and Penicillin,… »
A synthetic, colchicine analogue with potential antineoplastic activity. Mivobulin targets and binds to colchicine-binding site on tubulin, thereby inhibiting microtubule polymerization, the… »
An anticancer drug that belongs to the family of drugs called mitotic inhibitors. Also called CI-980. »
Mixed; being composed of a combination of normal and tumor cells. »
A carcinoma that arises from the pancreas showing either extensive mucin accumulation and acinar neoplastic cells or a mixture of columnar or… »
A carcinoma that arises from the pancreas showing a mixture of acinar and neuroendocrine malignant cells. »
A very rare carcinoma that arises from the pancreas showing a mixture of acinar, neuroendocrine, and ductal carcinoma elements. »
A morphologic variant of alveolar rhabdomyosarcoma composed of alveolar and embryonic components. It is characterized by the presence of spindle cells with… »
A tumor of mixed cell type with astrocytic components as well as ependymoma components. »
A cancer vaccine containing a mixture of killed bacteria with potential immunostimulatory and antineoplastic activities. Mixed bacteria vaccine (MBV or Coley's toxins)… »
The determination of the number of mixed casts present in a urine sample. »
A laboratory procedure that is performed in more than one of these laboratory specializations: anatomic pathology, clinical pathology, or molecular pathology. … »
An adenocarcinoma characterized by the presence of a mixed malignant glandular cell population. »
An adenoma characterized by the presence of a mixed epithelial cell population. »
Malignant lymphoma characterized by the presence of a mixed population of cells, with the smaller cells resembling lymphocytes and the larger ones… »
Wilms tumor of the kidney characterized by the presence of blastema, epithelial, and mesenchymal components (triphasic pattern) or a combination of two… »
A melanoma arising from the choroid, ciliary body, or the iris. It is characterized by the presence of a mixture of spindle… »
A subtype of classical Hodgkin lymphoma with a mixed inflammatory stroma containing Hodgkin and Reed-Sternberg cells. »
A subtype of cerebral palsy characterized by both the tight muscle tone of spastic cerebral palsy and the writhing, involuntary muscle movements… »
Hearing loss characterized by a combination of conductive and sensorineural hearing loss. It is caused by problems in both the inner… »
A congenital mesoblastic nephroma characterized by the presence of classic and cellular areas. »
An autoimmune overlap syndrome characterized by the presence of symptoms of systemic lupus erythematosus, systemic scleroderma, and polymyositis. »
A carcinoma that arises from the pancreas showing a mixture of ductal and neuroendocrine malignant cells in both the primary tumor and… »
A germ cell tumor characterized by the presence of an embryonal carcinoma component and a teratoma component. »
A rare primary neoplasm of the uterine corpus characterized by the presence of endometrial stromal and smooth muscle components. »
A hepatoblastoma characterized by the presence of fetal and embryonal epithelial components and a mesenchymal component. »
A rare, usually benign neoplasm that arises from the kidney. It usually affects females. It is characterized by the presence of a… »
An invasive breast carcinoma characterized by the presence of a mesenchymal cellular component. The mesenchymal cellular component ranges from cartilaginous and… »
A melanoma characterized by the presence of malignant large epithelioid melanocytes and malignant spindle-shaped melanocytes. »
These enzymes use molecular oxygen catalyze the donation of one oxygen atom to a substrate specific site, while the other atom is… »
A malignant germ cell tumor characterized by the presence of at least two different germ cell components. The different germ cell components… »
A biphasic neoplasm that arises from the ovary or the testis. It is characterized by the presence of neoplastic germ cells and… »
A brain tumor that forms from more than one type of brain cell, usually astrocytes and oligodendrocytes. »
A hepatoblastoma characterized by the presence of mixed epithelial and mesenchymal components and additional tissues such as striated muscle, bone, epithelial tissues,… »
A malignant neoplasm characterized by the presence of a combination of liposarcomatous morphologic subtypes: myxoid/round cell and well differentiated/dedifferentiated liposarcoma or myxoid/round… »
A breast carcinoma characterized by the presence of a lobular and a ductal component. The ductal component comprises less than 50 percent… »
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several… »
A group of tumors affecting the female reproductive system, characterized by the presence of epithelial and stromal elements. It includes the following… »
MIN NOS that has a mixture of features. »
A rare morphologic variant of bronchiolo-alveolar lung carcinoma characterized by the presence of both mucin and non-mucin producing cells. »
A tumor composed of at least two distinct cellular populations. »
Point mutations at various locations in a DNA sequence from eukaryotic or prokaryotic organisms in which a nucleotide substitution, deletion or insertion… »
An acute leukemia of ambiguous lineage. It is characterized by the presence of either separate populations of blasts of more than… »
A rare mixed phenotype acute leukemia in which the blasts also carry the translocation (9;22)(q34;q11.2) by karyotypic analysis or the BCR-ABL1 translocation… »
A rare mixed phenotype acute leukemia in which the blasts also carry a translocation involving the MLL gene. The prognosis is… »
A rare mixed phenotype acute leukemia in which the blasts express B-lymphoid and myeloid lineage markers but are negative for MLL translocation… »
A rare mixed phenotype acute leukemia in which the blasts express T-lymphoid and myeloid lineage markers but are negative for MLL translocation… »
A disorder characterized by an impairment in the development of an individual's expressive and receptive language capabilities which is in contrast to… »
Improvement in some organs, but worsening in others in chronic Graft versus Host Disease (cGVHD); this is categorized as progressive disease. … »
Greater than 50% reduction of any measurable lesion (primary or metastases) with, less than 50% reduction in any other site; no new… »
An infrequent pituitary gland adenoma composed of an admixture of acidophilic and chromophobic cells that produce growth hormone and prolactin respectively. … »
A squamous cell carcinoma that arises from the penis and is characterized by a mixture of morphologic patterns (e.g., high grade squamous… »
A benign or malignant neoplasm that arises from the parotid gland. It is characterized by the presence of epithelial and mesenchymal… »
A benign or malignant neoplasm that arises from the salivary glands. It is characterized by the presence of epithelial and mesenchymal… »
A rare, benign, slow-growing and painless neoplasm of sweat glands. It usually arises in the head and neck. It is characterized by… »
A clonal proliferation of cells frequently with a mixture of mesenchymal and epithelial patterns of differentiation. »
A subtype of delusional disorder applied when no one delusional theme (such as grandiose, jealous, persecutory) predominates. »
A term referring to conventional osteosarcomas which do not have a dominant matrix pattern and contain a mixture of osteoid matrix in… »
Second generation of antisense agents with segments of modified phosphorothioate oligonucleotides. The most extensively studied and used agents contain 2'-substituted modifications, such… »
A mechanical device designed to blend materials or an electronic device designed to blend signals. »
A class that provides a certain functionality to be inherited by a subclass, but is not meant to stand alone. »
Any mixing operation not otherwise specified. »
A substance consisting of two or more substances mixed together (not in fixed proportions and not with chemical bonding). »
A substance that occurs as part of a mixture substance. »
A substance being studied in the treatment of many types of cancer. MK-0646 binds to a protein called insulin-like growth factor receptor… »
Sustancia en estudio para el tratamiento de muchos tipos de cánceres. MK-0646 se adhiere a una proteína llamada receptor del factor de… »
A synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of… »
A substance being studied in the treatment of cancer. It blocks signals between growing cells and may kill cancer cells. It is… »
Sustancia en estudio para el tratamiento de cáncer. Bloquea las señales entre las células en crecimiento y podría destruir las células… »
An orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation… »
This gene is involved in cellular proliferation. »
Human MKI67 wild-type allele is located within 10q25-qter and is approximately 30 kb in length. This allele, which encodes antigen KI-67 immunoprotein,… »
MKL/myocardin-like protein 1 (931 aa, ~99 kDa) is encoded by the human MKL1 gene. This protein is involved in both transcriptional activation… »
Human MKL1 wild-type allele is located in the vicinity of 22q13 and is approximately 226 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(1;22)(p13;q13) which fuses the 5' portion of the MKL1 gene to the 3'… »
This gene is involved in signal transduction and transcriptional regulation. »
Human MKNK1 wild type allele, which is located in the vicinity of 1p33 and is approximately 47 kb in length. This allele,… »
This gene is involved in the phosphorylation of proteins. »
Human MKNK2 wild-type allele is located in the vicinity of 19p13.3 and is approximately 14 kb in length. This allele, which encodes… »
This gene is involved in ubiquitylation. »
Human MKRN1 wild-type allele is located in the vicinity of 7q34 and is approximately 27 kb in length. This allele, which encodes… »
The cluster of metric units based on the meter, the kilogram, and the second as base units. »
A measure of volume in the metric system. One thousand mls equal one liter. Also called cc, cubic centimeter, and… »
Medida de volumen en el sistema métrico. Mil ml equivalen a un litro. También se llama cc, centímetro cúbico, y… »
This gene plays a role in the development and maturation of melanosomes. »
Human MLANA wild-type allele is located in the vicinity of 9p24.1 and is approximately 20 kb in length. This allele, which encodes… »
Human MLF1 wild-type allele is located in the vicinity of 3q25.1 and is approximately 36 kb in length. This allele, which encodes… »
MLH1 protein is a DNA-binding, DNA-mismatch repair protein, of the MutL/HexB family, that dimerizes with PMS2 or MLH3. MLH1 is part… »
Human MLH1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 57 kb in length. This allele, which encodes… »
This gene plays a role in DNA mismatch repair and is associated with hereditary nonpolyposis colon cancer. »
Human MLH3 wild-type allele is located in the vicinity of 14q24.3 and is approximately 35 kb in length. This allele, which encodes… »
This gene is involved in transcriptional regulation and alterations in the gene are associated with acute lymphoblastic leukemia. »
Human MLL wild-type allele is located in the vicinity of 11q23 and is approximately 89 kb in length. This allele, which encodes… »
Expression of a fusion protein that results from the insertion mutation ins(5;11)(q31;q13q23), which involves the human genes MLL and AFF1 and is… »
A fusion gene that results from a chromosomal translocation t(10;11)(p11.2;q23) which fuses either exon 6 or 7 of the MLL gene to… »
A fusion protein encoded by the MLL/ABI1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene (~12 kb) that results from a chromosomal translocation t(4;11)(q21;q23) which fuses the 5' half of the MLL gene to… »
A fusion protein (~2250 aa, ~240 kDa) encoded by the MLL/AFF1 fusion gene. This protein is comprised of the N-terminal half of… »
A fusion gene that results from a chromosomal translocation t(2;11)(p15;q23) which fuses the 5' half of the MLL gene to the 3'… »
A fusion protein encoded by the MLL/AFF3 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(5;11)(q31;q23) which fuses the 5' half of the MLL gene to intron 12… »
A fusion protein encoded by the MLL/ARHGAP26 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal rearrangement which fuses the exon 6 of the MLL gene to most of the… »
A fusion protein encoded by the MLL/ARHGEF12 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(11;15)(q23;q14) which fuses exon 8 or exon 9 of the MLL gene and… »
A fusion protein encoded by the MLL/CASC5 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a rearrangement of the q arm of chromosome 11 which fuses the exon 6 of the… »
A fusion protein encoded by the MLL/CBL fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13.1) which fuses the first 7 exons of the MLL gene to most… »
A fusion protein encoded by the MLL/ELL gene. This protein is comprised of the N-terminal AT hook and DNA methyltransferase domains of… »
A fusion gene that results from a chromosomal translocation t(9;11)(q34;q23) which fuses exon 7 of the MLL gene to most of the… »
A fusion protein encoded by the MLL/FNBP1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(3;11)(q25;q23) which fuses either exon 7 or 8 of the MLL gene to… »
A fusion protein encoded by the MLL/GMPS fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(11;14)(q23;q24) which fuses exon 8 of the MLL gene to the 3' half… »
A fusion protein encoded by the MLL/GPHN fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(11;17)(q23;q12-21) which fuses the 5' half of the MLL gene to the 3'… »
A fusion protein encoded by the MLL/LASP1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(3;11)(q28;q23) which fuses exon 8 of the MLL gene to exon 9 of… »
A fusion protein encoded by the MLL/LPP fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal inversion inv(11)(q21q23) which fuses the exon 7 of the MLL gene to exon 2… »
A fusion protein encoded by the MLL/MAML2 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13.3) which fuses the 5' half of the MLL gene to most of… »
A fusion protein encoded by the MLL/MLLT1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(10;11)(p12;q23) which fuses the 5' half of the MLL gene to the 3'… »
A fusion protein encoded by the MLL/MLLT10 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(1;11)(q21;q23) which fuses the first 6 exons of the MLL gene to the… »
A fusion protein encoded by the MLL/MLLT11 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(9;11)(p22;q23) which fuses the 5' half of the MLL gene to the 3'… »
A fusion protein encoded by the MLL/MLLT3 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(6;11)(q27;q23) which fuses the 5' half of the MLL gene to most of… »
A fusion protein encoded by the MLL/MLLT4 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(11;12)(q23;q13) which fuses exon 9 of the MLL gene to most of the… »
A fusion protein encoded by the MLL/SARNP fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(11;22)(q23;q11.2) which fuses exon 7 of the MLL gene to exon 3 of… »
A fusion protein encoded by the MLL/SEPT5 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(X;11)(q24;q23) which fuses the 5' half of the MLL gene to exon 1… »
A fusion protein encoded by the MLL/SEPT6 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13) which fuses the exon 6 of the MLL gene to most of… »
A fusion protein encoded by the MLL/SH3GL1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL… »
Human MLL2 wild-type allele is located within 12q12-q14 and is approximately 36 kb in length. This allele, which encodes myeloid/lymphoid or mixed-lineage… »
Human MLL3 wild-type allele is located in the vicinity of 7q36.1 and is approximately 302 kb in length. This allele, which encodes… »
This gene is involved in transcriptional regulation, cell cycle progression and protein methylation. »
Human MLL5 wild-type allele is located in the vicinity of 7q22.1 and is approximately 100 kb in length. This allele, which encodes… »
This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia. »
Human MLLT1 wild-type allele is located in the vicinity of 19p13.3 and is approximately 70 kb in length. This allele, which encodes… »
This gene may be involved in transcriptional regulation. »
Human MLLT10 wild-type allele is located in the vicinity of 10p12 and is approximately 209 kb in length. This allele, which encodes… »
A fusion gene that results from a complex chromosomal rearrangement invins(10;11)(p12;q23q12) which fuses the 5' end of the MLLT10 gene with the… »
A fusion gene that results from a chromosomal translocation t(10;11)(p13;q14) which fuses the 5' end of the MLLT10 gene to the extreme… »
A fusion protein encoded by the MLLT10/PICALM fusion gene. This protein is comprised of the N-terminal zinc finger domain of protein AF-10… »
This gene is involved in mitochondrial functions. »
Human MLLT11 wild-type allele is located in the vicinity of 1q21 and is approximately 11 kb in length. This allele, which encodes… »
This gene plays a role in transcriptional regulation and translocations in the gene are associated with leukemia. »
Human MLLT3 wild-type allele is located in the vicinity of 9p22 and is approximately 281 kb in length. This allele, which encodes… »
Expression of a fusion protein that results from a t(9;11)(p22;q23) translocation, which involves the human genes MLL and MLLT3 and is associated… »
This gene is involved in cell adhesion and cytoskeletal modeling. »
Human MLLT4 wild-type allele is located in the vicinity of 6q27 and is approximately 145 kb in length. This allele, which encodes… »
This gene is involved in transcriptional regulation and aberrations in the gene are associated with acute leukemias due to chromosomal translocations. … »
Human MLLT6 wild-type allele is located in the vicinity of 17q21 and is approximately 22 kb in length. This allele, which encodes… »
A substance being studied as a treatment for atherosclerosis (a build-up of fat in the arteries). It is also being studied in… »
Sustancia en estudio para el tratamiento de la ateroesclerosis (acumulación de grasa en las arterias). También está en estudio para… »
A substance that is being studied in the treatment of prostate cancer. It belongs to the family of drugs called antibody drug… »
Sustancia en estudio para el tratamiento del cáncer de próstata. Es un tipo de conjugado de anticuerpos. También se llama MLN591DM1. … »
Encoded by human MLN51 Gene, ubiquitous cytoplasmic 76.3 kD MLN51 Protein contains 703 residues that share no significant homology with any known… »
A substance being studied in the treatment of some types of cancer. It may stop cancer cell growth by blocking certain… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer. Podría detener el crecimiento de células cancerosas al bloquear ciertas… »
A substance that is being studied in the treatment of prostate cancer. It belongs to the family of drugs called antibody drug… »
Sustancia en estudio para el tratamiento del cáncer de próstata. Es un tipo de conjugado de anticuerpos. También se llama MLN2704. … »
Expressed in various tissues by human TRPM5 Gene, Transient Receptor Potential Cation Channel Subfamily M Member 5 is related to the transient… »
This gene plays a role in both DNA binding and transcriptional regulation. »
Human MLXIPL wild-type allele is located in the vicinity of 7q11.23 and is approximately 31 kb in length. This allele, which encodes… »
The amount of a substance equal to a thousandth of a mole (a measure of the amount of a substance). Also… »
Cantidad de una sustancia igual a una milésima de mol (medida de la cantidad de una sustancia). También se llama milimol. … »
This gene is involved in vitamin metabolism. »
Human MMADHC wild-type allele is located in the vicinity of 2q23.2 and is approximately 18 kb in length. This allele, which encodes… »
Human MME wild-type allele is located within 3q25.1-q25.2 and is approximately 104 kb in length. This allele, which encodes neprilysin protein, plays… »
An orally-active synthetic hydroxamic acid derivative with potential antineoplastic activity. MMI270 inhibits a broad spectrum of matrix metalloproteinases (MMPs) (specifically MMP-1,… »
A rare syndrome characterized by the presence of an enlarged and weak bladder (megacystis), a very small large intestine (microcolon), and weak… »
A rare type of tumor that is a mixture of carcinoma and sarcoma cells. MMMT usually occurs in the uterus. Also called… »
Tipo de tumor poco común que es una mezcla de células de carcinoma y de sarcoma. Por lo general, el MMMT se… »
This gene plays a role in cell migration, inflammation and the regulation of extracellular matrix remodeling. »
Human MMP1 wild-type allele is located in the vicinity of 11q22.3 and is approximately 8 kb in length. This allele, which encodes… »
This gene plays a role in degradation of proteoglycans and fibronectin. »
Human MMP10 wild-type allele is located in the vicinity of 11q22.3 and is approximately 10 kb in length. This allele, which encodes… »
This gene plays a role in embryogenesis. »
Human MMP11 wild-type allele is located in the vicinity of 22q11.23 and is approximately 11 kb in length. This allele, which encodes… »
This gene plays a role in proteolysis of collagen. »
Human MMP13 wild-type allele is located in the vicinity of 11q22.3 and is approximately 13 kb in length. This allele, which encodes… »
This gene is involved in cell migration and motility. »
Human MMP14 wild-type allele is located within 14q11-q12 and is approximately 11 kb in length. This allele, which encodes matrix metalloproteinase-14, plays… »
This gene is involved in angiogenesis, inflammation and the regulation of extracellular matrix remodeling. »
Human MMP2 wild-type allele is located within 16q13-q21 and is approximately 27 kb in length. This allele, which encodes 72 kDa type… »
This gene plays a role in wound repair and the regulation of extracellular matrix remodeling. »
Human MMP3 wild-type allele is located in the vicinity of 11q22.3 and is approximately 8 kb in length. This allele, which encodes… »
Human MMP7 wild-type allele is located within 11q21-q22 and is approximately 10 kb in length. This allele, which encodes matrilysin protein, is… »
Human MMP8 wild-type allele is located in the vicinity of 11q22.3 and is approximately 12 kb in length. This allele, which encodes… »
This gene plays a role in inflammation, keratinocyte growth and the regulation of matrix remodeling. »
Human MMP9 wild-type allele is located within 20q11.2-q13.1 and is approximately 8 kb in length. This allele, which encodes matrix metalloproteinase-9 protein,… »
Modified Medical Research Council Dyspnea Scale - Description of breathlessness. »
A question associated with the MMRC questionnaire. »
The Mini-Mental State Examination (MMSE) Question 1. »
The Mini-Mental State Examination (MMSE) Question 10. »
The Mini-Mental State Examination (MMSE) Question 11. »
The Mini-Mental State Examination (MMSE) Question 12. »
The Mini-Mental State Examination (MMSE) Question 1A. »
The Mini-Mental State Examination (MMSE) Question 1B. »
The Mini-Mental State Examination (MMSE) Question 1C. »
The Mini-Mental State Examination (MMSE) Question 1D. »
The Mini-Mental State Examination (MMSE) Question 1E. »
The Mini-Mental State Examination (MMSE) Question 2. »
The Mini-Mental State Examination (MMSE) Question 2A. »
The Mini-Mental State Examination (MMSE) Question 2B. »
The Mini-Mental State Examination (MMSE) Question 2C. »
The Mini-Mental State Examination (MMSE) Question 2D. »
The Mini-Mental State Examination (MMSE) Question 2E. »
The Mini-Mental State Examination (MMSE) Question 3. »
The Mini-Mental State Examination (MMSE) Question 3A. »
The Mini-Mental State Examination (MMSE) Question 3B. »
The Mini-Mental State Examination (MMSE) Question 3C. »
The Mini-Mental State Examination (MMSE) Question 4. »
The Mini-Mental State Examination (MMSE) Question 4C. »
The Mini-Mental State Examination (MMSE) Question 4C1. »
The Mini-Mental State Examination (MMSE) Question 4C2. »
The Mini-Mental State Examination (MMSE) Question 4C3. »
The Mini-Mental State Examination (MMSE) Question 4C4. »
The Mini-Mental State Examination (MMSE) Question 4C5. »
The Mini-Mental State Examination (MMSE) Question 4S. »
The Mini-Mental State Examination (MMSE) Question 4S1. »
The Mini-Mental State Examination (MMSE) Question 4S2. »
The Mini-Mental State Examination (MMSE) Question 4S3. »
The Mini-Mental State Examination (MMSE) Question 4S4. »
The Mini-Mental State Examination (MMSE) Question 4S5. »
The Mini-Mental State Examination (MMSE) Question 5. »
The Mini-Mental State Examination (MMSE) Question 5A. »
The Mini-Mental State Examination (MMSE) Question 5B. »
The Mini-Mental State Examination (MMSE) Question 5C. »
The Mini-Mental State Examination (MMSE) Question 6. »
The Mini-Mental State Examination (MMSE) Question 6A. »
The Mini-Mental State Examination (MMSE) Question 6B. »
The Mini-Mental State Examination (MMSE) Question 7. »
The Mini-Mental State Examination (MMSE) Question 8. »
The Mini-Mental State Examination (MMSE) Question 8A. »
The Mini-Mental State Examination (MMSE) Question 8B. »
The Mini-Mental State Examination (MMSE) Question 8C. »
The Mini-Mental State Examination (MMSE) Question 9. »
A question associated with the MMSE questionnaire. »
Human MN1 wild-type allele is located in the vicinity of 22q11; 22q12.1 and is approximately 53 kb in length. This allele, which… »
A fusion gene that results from a chromosomal translocation t(12;22)(p13;q11-12) that fuses most of the MN1 gene to the 3' portion of… »
A fusion protein encoded by the MN1/ETV6 fusion gene. This protein is comprised of most of the probable tumor suppressor protein MN1… »
A molecular genetic technique where genome-wide sequencing is performed on chromosomal DNA that is resistant to treatment with micrococcal nuclease. This technique… »
This gene is involved in the mediation of protein-protein interactions that are essential for cell cycle regulation. »
Human MNAT1 wild-type allele is located in the vicinity of 14q23 and is approximately 234 kb in length. This allele, which encodes… »
Michigan Neuropathy Screening Instrument (MNSI) History; are you able to sense your feet when you walk? »
Michigan Neuropathy Screening Instrument (MNSI) History; when you get into the tub or shower, are you able to tell the hot water… »
Michigan Neuropathy Screening Instrument (MNSI) History; do you ever have any burning pain in your legs and/or feet? »
Michigan Neuropathy Screening Instrument (MNSI) History; has your doctor ever told you that you have diabetic neuropathy? »
Michigan Neuropathy Screening Instrument (MNSI) History; have you ever had an amputation? »
Michigan Neuropathy Screening Instrument (MNSI) History; do you feel weak all over most of the time? »
Michigan Neuropathy Screening Instrument (MNSI) History; are your feet too sensitive to touch? »
Michigan Neuropathy Screening Instrument (MNSI) History; total. »
Michigan Neuropathy Screening Instrument (MNSI) History; does it hurt when the bed covers touch your skin? »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; left ankle reflexes. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of left foot - normal. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of left foot - deformities. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of left foot - dry skin, callus. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of left foot - fissure. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of left foot - infection. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; left foot - monofilament. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of left foot - other, specify. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; left foot - ulceration. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; left foot - vibration perception at great toe. »
Michigan Neuropathy Screening Instrument (MNSI) History; are your legs and/or feet numb? »
Michigan Neuropathy Screening Instrument (MNSI) History; do your legs hurt when you walk? »
Michigan Neuropathy Screening Instrument (MNSI) History; do you get muscle cramps in your legs and/or feet? »
Michigan Neuropathy Screening Instrument (MNSI) History; have you ever had an open sore on your foot? »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; total score. »
Michigan Neuropathy Screening Instrument (MNSI) History; do you ever have any prickling feelings in your legs or feet? »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; right ankle reflexes. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of right foot - normal. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of right foot - deformities. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of right foot - dry skin, callus. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of right foot - fissure. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of right foot - infection. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; right foot - monofilament. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; appearance of right foot - other, specify. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; right foot - ulceration. »
Michigan Neuropathy Screening Instrument (MNSI) Physical assessment; right foot - vibration perception at great toe. »
Michigan Neuropathy Screening Instrument (MNSI) History; is the skin on your feet so dry that it cracks open? »
Michigan Neuropathy Screening Instrument (MNSI) History; are your symptoms worse at night? »
A question associated with the MNSI questionnaire. »
Human MNX1 wild-type allele is located in the vicinity of 7q36 and is approximately 17 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(7;12)(q36;p13) which fuses the first exon of the MNX1 gene with exon 3… »
A fusion protein encoded by the MNX1/ETV6 fusion gene. This protein is comprised of the N-terminal portion of the motor neuron and… »
A monoclonal antibody B3, recognizing the tumor-associated Lewis Y antigen, is conjugated to a backbone-substituted derivative of DTPA, 2-(p-isothiocyanatobenzyl)-cyclohexyl-diethylenetriaminepentaacetic acid (CHX-A… »
A monoclonal antibody directed against the neurohormone bombesin that is conjugated to diethylenetriaminepenta-acetic acid (DPTA), a bifunctional chelating agent that allows the… »
A monoclonal antibody directed against the neurohormone bombesin that is conjugated to isothiocyanobenzyl diethylenetriaminepentaacetic acid (ITC-D), a bifunctional chelating agent that allows… »
A substance being studied in the treatment of cancer. It binds to a molecule called GD2, which is found in greater than… »
Sustancia en estudio para el tratamiento de cáncer. Se une a una molécula que se llama GD2, que se encuentra en cantidades… »
A substance being studied in the treatment of myelodysplastic syndromes and some types of leukemia. It binds to CD33, a protein on… »
Sustancia en estudio para el tratamiento de los síndromes mielodisplásicos y algunos tipos de leucemia. Se una a la proteína CD33 en… »
Mobile communications system that uses a combination of radio wave transmission and conventional telephone switching to permit telephone communication to and from… »
The sequence of numbers or characters, that when dialed, connects to a particular mobile telephone. »
Mobility aids help you walk or move from place to place if you are disabled or have an injury. They include »
Blood stem cells found in the circulation after being stimulated to leave the bone marrow, usually by treatment with a cytokine or… »
A genus of anaerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria and the family Actinomycetaceae. »
A species of anaerobic, Gram positive, curved rod shaped bacterium assigned to the phylum Actinobacteria. This species is motile by one to… »
A subspecies of anaerobic, Gram positive, curved rod shaped bacterium assigned to the phylum Actinobacteria and the species Mobiluncus curtisii. This subspecies… »
A species of anaerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is motile by one to eight… »
A cardiac rhythm characterized by progressive PR prolongation and shortening of RR interval until P wave is blocked. The pause after the… »
A cardiac rhythm characterized by a regular sinus/atrial rhythm with intermittent nonconducted P waves. There is a constant PR interval in the… »
A very rare congenital syndrome affecting the sixth and seventh cranial nerves. It is characterized by facial paralysis leading to lack of… »
A substance being studied in the treatment of several types of cancer. It blocks enzymes needed for cell division and may kill… »
Sustancia en estudio para el tratamiento de varios tipos de cáncer. Bloquea enzimas que las células necesitan para multiplicarse y podría destruir… »
Líquido espeso y resbaladizo producido por las membranas que revisten ciertos órganos del cuerpo; por ejemplo, la nariz, la boca, la garganta… »
A drug that is being studied as a treatment for fatigue in patients with cancer. It belongs to the family of drugs… »
Medicamento en estudio para el tratamiento de la fatiga en los pacientes de cáncer. Es un estimulante. »
The most common chromosome number within a population or sample. »
Método de tratamiento. Por ejemplo, la cirugía y la quimioterapia son modalidades de tratamiento. »
Ejercicio de salud que combina el enfoque mental, el control de la respiración y los movimientos del cuerpo para ayudar a la… »
A scoring system of disease severity in patients with end-stage liver disease. It is used to help prioritize allocation of liver allografts… »
The identifier assigned to a particular design of a device. »
The use of statistical analysis, computer analysis, or model organisms to predict outcomes of research. (doegenomes.org) »
Any representation of the individual steps in a metabolic pathway of a cell. »
Using mathematical methods to simulate processes to predict the interaction of proteins at the functional level. »
Animal que tiene una enfermedad que es la misma o similar a una enfermedad en los seres humanos. Los modelos animales se… »
Programa de computación que usa las estadísticas para predecir el riesgo de padecer de cáncer de mama (seno) basándose en los antecedentes… »
Programa de computación que utiliza antecedentes personales y familiares para calcular la probabilidad de que una mujer enferme de cáncer de… »
Programa de computación que utiliza antecedentes personales y familiares para calcular la probabilidad de que una mujer enferme de cáncer de… »
Células, tejidos o animales que se usan para estudiar el desarrollo y avance del cáncer, y para probar nuevos tratamientos antes de… »
An electronic device for converting between serial data from a computer and an audio signal suitable for transmission over a telephone line… »
A question about moderate activities such as moving a table, pushing a vacuum cleaner, bowling, or playing golf. »
An experience that is alleviated with simple therapeutic treatments. The event impacts usual daily activities. Includes laboratory test alterations indicating injury, but… »
A baseline fetal heart rate with a detectable amplitude range that is greater than 6 but less than or equal to 25… »
Evidence of moderate retrograde blood flow through the valve(s) of the heart. »
The cardiac valve orifice is abnormally narrow, to a moderate degree. »
A question about whether an individual has or had a moderate likelihood of dozing. »
A morphologic finding indicating the presence of moderate dysplastic cellular changes and moderate architectural changes in the glandular epithelium of the colonic… »
A morphologic finding indicating the presence of moderate dysplastic cellular changes and moderate architectural changes in the epithelium of the esophageal… »
20-60 minutes of exercise which elevates your heart rate to 60-80% of your maximum heart rate performed at least 3-4 times per… »
A response indicating that an individual has or had moderate pain or discomfort. »
A morphologic finding indicating the presence of moderate dysplastic cellular changes and moderate architectural changes in the glandular epithelium of the rectal… »
A level of sedation in which a person is asleep but wakes when spoken to or touched. Moderate sedation is caused by… »
The regular strength or dosage quantity of a therapeutic agent prescribed to be taken at one time or at stated intervals. … »
Moderately less than normal amount of blood that is forced from the heart ventricle to produce cardiac output. Quantitatively, the ejection fraction… »
A response indicating that an individual has or had moderate anxiety or depression. »
Describes tumor cells that have lost some of the appearance of normal cells. They tend to grow and spread at a faster… »
A hepatocellular carcinoma characterized by the presence of malignant cells with abundant eosinophilic cytoplasm forming trabecular and pseudoglandular patterns. It is… »
Combined glandular formation as well as foci of fusion/solid areas. »
An invasive prostate adenocarcinoma characterized by the presence of malignant cells exhibiting moderate differentiation. »
A neoplasm of keratinocytes with local invasion and/or metastasis with evidence of keratinization apparent in greater than 1/3 of the neoplasm but… »
Heating of tumors to the 40.5-42.5C range. Increases the oxygenation of tumors thereby enhancing the effect of radiation therapy. »
Técnica que se usa para ayudar a las personas a cambiar la manera de reaccionar ante ciertos factores ambientales que les provocan… »
Células que han sido alteradas para que contengan material genético distinto al que contenían originalmente. »
The act of making a change or the change made; changed or altered in form or character. »
An indication that a change in treatment or a change to a device will be required following an adverse event. »
A microscopy staining method, that does not utilize heat in the slide preparation, used to examine a specimen for the presence of… »
Indicates the person or authoritative body who changed an item. »
A dietary supplement containing the modified citrus pectin (MCP) derived from the soluble fiber of citrus fruit peels and a galectin-3 inhibitor… »
An abbreviation for a combination chemotherapy regimen that is used to treat colorectal cancer. It includes the drugs leucovorin calcium (folinic acid),… »
An abbreviation for a combination chemotherapy regimen that is used to treat colorectal cancer. It includes the drugs leucovorin calcium (folinic acid),… »
A standardized rating scale originally developed by Hachinski et al in 1975 and later modified by Rosen et al in 1980 to… »
A standardized rating scale developed by Mahler and Wells in 1988, which is a general scale used to measure the rating of… »
A measure proposed by Wolchok et al. (Clin Cancer Res 2009;15:7412-7420) to determine the extent of an antitumor response to a particular… »
The evaluation of the antitumor response shows a complete disappearance of all lesions (whether measurable or not) and no new lesions. All… »
The finding of a growth smaller than 5 mm x 5 mm that was not present at the previous evaluation. Its presence… »
The evaluation of the antitumor response shows that the sum of the longest diameters of target and new measurable lesions has decreased… »
The evaluation of the antitumor response shows that the sum of the longest diameters of target and new measurable lesions increases by… »
The evaluation of the antitumor response shows that the sum of the longest diameters of target and new measurable lesions do not… »
A classification algorithm based on the robust classification method called partitioning around medoids. MPAM includes terms in the objective function to penalize… »
Surgery to remove the uterus, cervix, upper part of the vagina, and nearby ligaments and tissues. Nearby lymph nodes may also be… »
Surgery for breast cancer in which the breast, most or all of the lymph nodes under the arm, and the lining over… »
A surgical procedure in which all the ipsilateral cervical lymph node groups of the neck are removed but the internal jugular vein,… »
Surgery to remove most, but not all, of the vulva (the external female genital organs, including the clitoris, vaginal lips, and the… »
A six point scale that qualifies a person's physical abilities following a cerebrovascular accident. It is commonly used as a primary endpoint… »
A standardized questionnaire originally developed by John Rankin in 1957, and later modified by Van Swieten et al in 1988, which is… »
A solid, semi-solid, solution or suspension exhibiting an altered inherent rate of release of active and/or inert ingredient(s). »
A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor… »
Sustancia que se toma de las plantas y que está en estudio para el tratamiento de cáncer. Podría ayudar a los medicamentos… »
Medicamento que actúa como un estrógeno sobre algunos tejidos, pero bloquea el efecto del estrógeno sobre otros tejidos. El tamoxifeno y el… »
To adjust, or change. »
An electronic device designed to vary the frequency, amplitude, or phase of an electromagnetic signal. »
A self-contained component (unit or item) that is used in combination with other components. »
A genus of facultatively anaerobic ,Gram negative, rod shaped bacterium in the phylum Proteobacteria and the family Enterobacteriaceae. »
A species of facultatively anaerobic ,Gram negative, rod shaped bacterium in the phylum Proteobacteria. This species is nonmotile, indole negative, resistant to… »
Moesin (577 aa, ~68 kDa) is encoded by the human MSN gene. This protein plays a role in both cell adhesion and… »
A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, moexipril is hydrolyzed into its active form moexiprilat, which… »
The hydrochloride salt form of moexipril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexipril hydrochloride is hydrolized… »
A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexiprilat competitively inhibits ACE, thereby blocking the conversion of angiotensin I to… »
An arotinoic acid derivative with a morpholine structure in the polar end group with differentiation inducing and antineoplastic activity. Like other retinoic… »
A humanized monoclonal antibody directed against C-C chemokine receptor 4 (CCR4) with potential anti-inflammatory and antineoplastic activities. Mogamulizumab selectively binds to and… »
A genus of anaerobic, Gram positive, rod shaped bacterium assigned to the phylum Firmicutes and the family Clostridiales XIII. »
A species of obligately anaerobic, Gram positive, rod shaped bacterium assigned to the phylum Firmicutes. This species is catalase negative, does not… »
A surgical procedure used to treat skin cancer. Individual layers of cancer tissue are removed and examined under a microscope one at… »
A surgical procedure used to treat skin cancer. Individual layers of cancer tissue are removed and examined under a microscope one at… »
The Drosophila gene moira (mor) encodes a non-specific RNA polymerase II transcription factor involved in chromatin modeling, which is a component of… »
A sterilization process that uses high temperature and moist air to kill microorganisms. The moist air is typically applied at increased atmospheric… »
Issue associated with damage inflicted upon the device or device components from water vapor or water in the immediate environment in which… »
Issue associated with an unsatisfactory humidity level in the storage or use environment which affects device performance. »
Muchos niños se orinan en la cama hasta los 5 años de edad o más. La vejiga del niño puede ser demasiado… »
Human RAGE wild-type allele is located within 14q32 and is approximately 79 kb in length. This allele, which encodes MAPK/MAK/MRK overlapping kinase… »
Tipo de nevus (mola) cuya apariencia es diferente a la de una mola común. Con frecuencia, Una mola atípica es más grande… »
Tumor de crecimiento lento que se forma con células trofoblásticas (células del útero que ayudan a que el embrión se adhiera al… »
Tipo de cáncer que crece en la pared muscular del útero. Se forma después de la concepción (fecundación de un óvulo por… »
A unit of amount of substance content measured as the number of moles of a solute substance (component) per mass of the… »
A slow-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta)… »
The relative number of moles of one substance to another in a chemical reaction. »
A grinding tooth with a broad crown; located behind the premolars. »
A unit of concentration of amount of substance measured as the number of moles of solute per liter of mixture. »
A process that forms a solid dosage unit by pouring or casting a melted agent into a prefabricated form. »
A country in eastern Europe, northeast of Romania. »
Molds are fungi that can be found both outdoors and indoors. They grow best in warm, damp and humid conditions. If you… »
A benign (not cancer) growth on the skin that is formed by a cluster of melanocytes (cells that make a substance called… »
Moles per day. »
A unit of amount of substance content (molality unit) defined as one mole of solute per one gram of solvent. »
Moles per hour. »
A unit amount of substance content (molality unit) defined as one mole of solute per one kilogram of solvent. »
A unit of concentration (molarity unit) equal to one mole of solute per one liter of solution. »
A unit of amount of substance content (molality unit) defined as one mole of solute per one milligram of solvent. »
A unit of concentration (molarity unit) equal to one mole of solute in one milliliter of solution. »
Moles per minute. »
A unit of fraction expressed as the ratio of the amount of substance of solute in moles to the amount of substance… »
Moles per second. »
Partícula más pequeña de una sustancia que tiene todas las propiedades físicas y químicas de esa sustancia. Las moléculas están compuestas por… »
En el campo de la medicina, un compuesto químico que se muestra prometedor como tratamiento de una enfermedad y puede conducir… »
Molécula biológica que se encuentra en la sangre, otros líquidos o tejidos corporales, es un signo de un proceso normal o anormal,… »
A molecular or cytogenic abnormality which occurs in either human disease states or disease models. »
A laboratory procedure that involves the study of tissues, cells, and fluids using DNA/RNA analysis techniques for the identification of characteristics and… »
Interdisciplinary studies combining cell biology and molecular biology. »
The study of biology at a molecular level. It chiefly concerns itself with understanding the interactions between the various systems of a… »
Molecular Biology Shared Resource provides molecular biology services to the Cancer Center investigators including automated DNA sequencing, DNA and peptide synthesis, protein… »
Research that focuses on the genetics and mechanisms of cell transformation; the role of oxygen radicals in the carcinogenesis process; and identification… »
Challenge to research community to revolutionize the classification of human tumors, away from classification based on morphology, toward a more clinically predictive… »
Studies of chromosome biology and behavior at the molecular level. »
The number of molecules contained in a specific volume. »
The process of identifying a disease by studying molecules, such as proteins, DNA, and RNA, in a tissue or fluid. »
Methods for diagnosis or monitoring of disease predisposition by translation and validation of molecular discoveries in medicine into the clinical diagnostic… »
The Molecular Diagnostics Laboratory Shared Resource provides support to Cancer Center investigators with specimen processing and tracking, DNA sequencing, microsatellite and SNP… »
The science of simulating the motions of a system of particles. (Karplus and Petsko) »
A molecular interaction in which a small molecule or structure becomes trapped, usually in a larger molecule or structure, due to non-covalent… »
The application of molecular biology techniques in answering epidemiological questions. »
Epidemiologic research on the environmental and genetic determinants of cancer. (Bypass Budget) »
The objective is to examine the role of genes that regulate the metabolism of environmental carcinogens in prostate cancer etiology. These… »
All cell types, depending on their functions, have unique, identifiable "signatures" - special characteristics such as which genes are active and what… »
The determination of the active and inactive genes present in a tumor sample. »
The methods and tools used for DNA analysis and manipulation. »
Any alteration in the inherited nucleic acid sequence of the genotype of an organism. »
The study of the flow and regulation of genetic information between DNA, RNA, and protein molecules. »
The visualization, characterization and measurement of biological processes at the molecular and cellular levels in humans and other living systems. Molecular imaging… »
The Molecular Imaging Shared Resource develops imaging reagents and methods that can be widely applied, develops imaging instruments, translates imaging methods to… »
Sub-discipline of immunology which investigates the molecular interaction involved in antigen recognition and processing, antibody-antigen interactions, cell-cell interactions, cell death, etc. … »
Involves temporary, non-covalent binding of two or more molecules as a result of intermolecular physical forces and often involves spatial complementarity between… »
The superficial layer of the cerebral cortex, containing nerve fibers, neuroglial cells, and occasional horizontal cells of Cajal. »
A biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or… »
Molecular Marker Activity involves temporary non-covalent interaction through intermolecular physical forces of attraction and spatial complementarity with a substance, such as a… »
The sum of the atomic masses of all atoms in a molecule, based on a scale in which the atomic masses of… »
A branch of medicine that develops ways to diagnose and treat disease by understanding the way genes, proteins, and other cellular molecules… »
Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures. … »
The computer simulation of chemical structures or processes; allows for the exploration, visualization, and manipulation of molecular structures and properties. »
An online resource of NCBI containing 3D macromolecular structures, including proteins and polynucleotides. Each structure is linked to the rest of the… »
A multidisciplinary field that focuses on the ability to engineer and manipulate functional systems at the molecular level. These systems are comprised… »
The branch of neurobiology that tries to understand the anatomy, physiology, and pathology of the nervous system by understanding the way that… »
Description of disease and disease processes based upon the underlying protein and genetic defects rather than by a description of morphology. … »
A series of actions among molecules in a cell that leads to a certain end point or cell function. »
Analysis of the RNA expression pattern in a tissue sample using molecular techniques. »
The branch of psychobiology that tries to understand cognitive functioning, including intellectual, memory, and related neurocognitive processes, by understanding the way that… »
The branch of pharmacology that tries to understand drug effects by understanding the way that receptors interact with proteins and other molecules… »
A procedure in which biomarkers (for example, biological molecules or changes in tumor cell DNA) are used to estimate a person’s risk… »
A variation in or modification of the molecular sequence of a gene or gene product. »
A form of gene and protein expression profiling that is indicative of the biological behavior of a tumor or cancer. This pattern… »
Every point of difference between premalignant or malignant cells and their normal counterparts is a potential target of opportunity for drug discovery… »
Proposed mechanism for providing resources for "mechanisms" researchers to provide evidence that a proposed new cancer relevant molecule is a good target… »
In medicine, a laboratory test that checks for certain genes, proteins, or other molecules in a sample of tissue, blood, or other… »
The branch of toxicology that tries to understand the health effects of poisons by understanding the way that genes, proteins, and molecules… »
The study of viral processes at the molecular level. Includes infection, replication, and expression of the viral genome. »
The sum of the atomic masses of all atoms in a molecule, based on a scale in which the atomic masses of… »
Suma de las masas atómicas de todos los átomos de una molécula, con base en una escala en la cual las masas… »
In cancer treatment, substances that kill cancer cells by targeting key molecules involved in cancer cell growth. »
The smallest particle of a substance that has all of the physical and chemical properties of that substance. Molecules are made up… »
A unit of measure of the fluorescence intensity of a fluorochrome-labeled sample, which is equivalent to the fluorescence intensity of a solution… »
Moles are growths on the skin. They happen when pigment cells in the skin, called melanocytes, grow in clusters. Moles are very… »
The hydrochloride salt form of molindone, a dihydroindolone compound with antipsychotic and anti-schizophrenic properties not structurally related to other major tranquilizers. Molindone… »
A unit of content of amount of substance measured as the number of moles of solute per kilogram of the mixture. … »
A genus of enveloped, brick-shaped viruses in the family Poxviridae. The genome is composed of linear, double-stranded DNA and the virus is… »
A species of enveloped and brick-shaped viruses in the Poxviridae family and Molluscipoxvirus genus. The genome is composed of non-segmented, linear double-stranded… »
A murine virus arising during the propagation of S37 mouse sarcoma, and causing lymphoid leukemia in mice. It also infects rats and… »
The TB strain of the Moloney Murine Leukemia Virus that arises during the propagation of the S37 mouse sarcoma model. »
A replication-defective murine sarcoma virus isolated from a rhabdomyosarcoma by Moloney in 1966. »
Issue associated with a solid device or device components being transformed into a molten or liquid state. »
An element with atomic symbol Mo, atomic number 42, and atomic weight 95.94. »
An orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with potential antineoplastic activity. JAK1/2 inhibitor CYT387 competes with JAK1/2… »
Medicamento que se usa en forma de crema para tratar ciertas afecciones de la piel y en forma de atomizador para tratar… »
A drug that is used in a cream to treat certain skin conditions and in a nasal spray to treat sinus problems… »
A drug that is used in a cream to treat certain skin conditions and in a nasal spray to treat sinus problems… »
A data type comprised of a quantity of money in some currency. »
Denotes the inhabitants of Mongolia, a person from there, or their descendants elsewhere. »
A rodent belonging to subfamily Gerbillinae, Meriones unguiculatus is the most common species of the gerbil subfamily. The Mongolian gerbil was first… »
A congenital mark on the skin near the base of the spine, consisting of scattered ectopic melanocytes in the dermis, that enlarges… »
A rare autosomal dominant inherited hair shaft disorder caused by mutations in the type II keratin gene. It is characterized by the… »
A type of pilosebaceous hamartoma characterized by the development of a linear, flesh colored, fine papular eruption on the head, neck and… »
In medicine, to regularly watch and check a person or condition to see if there is any change. Also refers to a… »
A device than includes a sensor designed to give information about the presence of a substance or the state of a… »
A unit of measure of ionization in a linear accelerator treatment beam within the treatment head. »
The act of observing something (and sometimes keeping a record of it). »
A recording device or display that continuously keeps track of the function, condition, or operation of the system or organism and warns… »
An extract made from the fruit of the chaste tree (Vitex agnus-castus) found in parts of Asia and Europe. It is claimed… »
Any haplorhine primate not belonging to the family Tarsiidae, Hylobatidae, Pongidae, or Hominidae; this does not correspond to any taxon. This group… »
Monkeypox is a rare viral disease. It occurs mostly in central and western Africa. Wild rodents and squirrels carry it, but it… »
Mono-ADP-ribosyltransferase sirtuin-6 (355 aa, ~ 39 kDa) is encoded by the human SIRT6 gene. This protein may be involved in post-translational protein… »
A type of drug used to treat depression. It stops the breakdown of certain chemicals in the brain that help improve a… »
A site on a protein that is a target for enzymatic cleavage, where the residue on the amino terminal side of the… »
A monobenzyl ether of hydroquinone with topical depigmentation activity. Although the exact mechanism of action of depigmentation is unknown, the metabolites of… »
A cell derived from a myeloid progenitor cell. It differentiates into a promonocyte. It is about 12 to 20 micrometer in diameter,… »
The determination of the number of monoblast cells present in a sample. »
The determination of the ratio of monoblast cells compared to leukocytes present in a sample. The measurement may be expressed as a… »
A less common form of myeloid sarcoma composed of monoblasts. Monoblastic sarcoma may precede or occur simultaneously with acute monoblastic… »
Monocarboxylate transporter 1 (500 aa, ~54 kDa) is encoded by the human SLC16A1 gene. This protein is involved in monocarboxylate transport across… »
An orally available inhibitor of monocarboxylate transporter 1 (MCT1), with potential antineoplastic activity. Upon oral administration, MCT1 inhibitor AZD3965 binds to MCT1… »
Monocarboxylate transporter 5 (487 aa, ~54 kDa) is encoded by the human SLC16A4 gene. This protein plays a role in the transport… »
A pregnancy involving two fetuses that share the same chorion but have separate amniotic sacs. »
A pregnancy involving two fetuses that share both the chorion and amniotic sac. These twins are invariably identical. »
Tipo de célula inmunitaria que se elabora en la médula ósea y viaja por la sangre hasta los tejidos del cuerpo; allí… »
A type of protein made in the laboratory that can bind to substances in the body, including cancer cells. There are many… »
A monoclonal immunoglobulin G 1 (IgG1) antibody to murine leukemia virus (MuLV) 1.4. »
A nonspecific monoclonal antibody Fab fragment for murine leukemia virus (MuLV) 1.4. Monoclonal antibody 1.4 F(ab) has been used as a… »
A cancer vaccine consisting of a humanized monoclonal antibody that mimics a tumor-associated antigen 791Tgp72 (also known as CD55). Vaccination with this… »
A murine monoclonal anti-idiotype antibody (anti-Id). Anti-Id 11D10 mimics a specific epitope of the high molecular weight human milk fat globule (HMFG)… »
A vaccine consisting of a monoclonal antibody (MoAb) directed against an idiotype that mimics a human milk fat globule (HMFG) membrane… »
A murine monoclonal antibody directed against the ganglioside GD2 with potential antineoplastic activity. Monoclonal antibody 14G2A binds to the ganglioside GD2 and… »
A human immunoglobulin M class monoclonal antibody that recognizes a 30- to 45-kilo dalton intracellular antigen expressed in colorectal cancer cells and… »
A murine monoclonal antibody directed against CD20, a cross-membrane ion channel phosphoprotein expressed by B cells, with potential antineoplastic activity. MOAB… »
A recombinant, murine monoclonal antibody directed against gastrin-releasing peptide, one of a number of bombesin-like peptides (BLP). Tumor cells, such as small… »
A humanized murine monoclonal antibody (MoAb) against the 17-1A antigen, with potential adjuvant therapeutic properties in colorectal cancer. 17-1A antigen (EpCAM), a… »
A murine monoclonal antibody that recognizes CD7 (previously known as 3A1), a cell surface antigen expressed by most normal mature peripheral T… »
A murine monoclonal antibody directed against the cell-surface, tumor-associated antigen ganglioside GD2. Vaccination with monoclonal antibody 3F8 may stimulate a host cytotoxic… »
A recombinant monoclonal antibody in which the heavy and light chain variable domains mimic a specific epitope of the tumor-associated protein carcinoembryonic… »
A synthetic antibody targeted against a cell surface glycoprotein (gp74) on a human c-Ha-ras oncogene transformed cell line. Monoclonal Antibody 45-2D9… »
A mouse monoclonal antibody (MoAb) with proteoglycan antigen detection and binding activity. Hybridomas of SP2/0 mouse myeloma cells and mouse spleen cells… »
A Fab fragment of the mouse monoclonal antibody (MoAb) 48.7. MoAb 48.7 Fab (fragment antigen binding) recognizes proteoglycan antigen expressed on the… »
A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2 with potential immunostimulating and antineoplastic activities. Upon administration, monoclonal… »
A monoclonal antibody against the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase overexpressed or upregulated in various types… »
A monoclonal antibody which recognizes the heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1, a potential epithelial marker in the detection of early lung cancer,… »
A murine IgM monoclonal antibody against Fas antigen with antineoplastic property. Fas antigen is a member of tumor necrosis factor family that… »
A mouse monoclonal antibody (MoAb) with binding specificity for the human melanoma-associated cell surface marker p97. Hybridomas of mouse myeloma cells and… »
A monovalent Fab fragment of the mouse monoclonal antibody (MoAb) 8.2 raised against human melanoma-associated cell surface marker p97. MoAb 8.2 Fab… »
A murine IgG2 monoclonal antibody (MoAb) 81C6 raised against the extracellular matrix antigen tenascin (hexabrachion), up-regulated in gliomas and other cancers. Conjugated… »
The Fab fragment of the 9.2.27 monoclonal antibody. 9.2.27 monoclonal antibody recognizes the high-molecular-weight melanoma-associated antigen (HMW-MAA), an antigen expressed on… »
A recombinant monoclonal antibody directed against the lymphocyte receptor CD2 with potential use in cancer immunotherapy. Activation of the CD2 molecule,… »
A recombinant monoclonal antibody directed against human T-cells designed to generate cytotoxic T lymphocyte (CTL) responses to tumor antigens with potential use… »
A mouse monoclonal antibody (MoAb) with binding specificity for the human melanoma-associated cell surface marker p97. Hybridomas of mouse myeloma cells and… »
A monovalent Fab fragment of the mouse monoclonal antibody (MoAb) 96.5, raised against an epitope from human melanoma-associated cell surface marker… »
An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer,… »
A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody A27.15 binds to the Tf receptor, blocking the… »
A humanized monoclonal antibody directed against the human A33 antigen. Monoclonal antibody A33 recognizes the human A33 antigen, a 43 KDa transmembrane… »
A chimeric monoclonal antibody against a Lewis-A-like glycotope (AbGn-7 antigen) with potential immunomodulating and antineoplastic activities. Monoclonal antibody AbGn-7 targets and binds… »
A monoclonal antibody that targets CD20, a B-cell-specific cell surface protein expressed on mature B lymphocytes. »
A murine IgG1 monoclonal antibody directed against Lewis Y antigen and related carbohydrate antigens of cell surface glycoproteins found in many tumor… »
The Fab fragment of the B6.2 monoclonal antibody that recognizes the B6.2 antigen, a 90,000-d glycoprotein found on the surface of human… »
A divalent F(ab)2 fragment of the monoclonal antibody (MoAb ) B6.2 directed against the tumor-associated glycoprotein (TAG-90) found on the surface of… »
A mouse monoclonal antibody of the immunoglobulin G kappa subclass directed against the tumor-associated glycoprotein TAG-72. TAG-72 may be expressed in a… »
An isotype-matched monoclonal antibody that is used as a control when testing other monoclonal antibodies. »
An idiotypic determinant of a monoclonal antibody directed against antigens preferentially expressed by the cell line BL-3 derived from bovine leukemia or… »
A monoclonal antibody directed against the neurohormone bombesin that is conjugated to diethylenetriaminepenta-acetic acid (DPTA), a bifunctional chelating agent that allows the… »
A monoclonal antibody directed against the neurohormone bombesin that is conjugated to isothiocyanobenzyl diethylenetriaminepentaacetic acid (ITC-D), a bifunctional chelating agent that allows… »
A murine and humanized monoclonal antibody that targets epitopes of epithelial glycoprotein mucin (MUC-1) on breast cancer surfaces. »
A human IgM monoclonal antibody (MoAb) directed against a human Cytomegalovirus (CMV) antigen. MoAb C-58 recognizes the p51 protein of viral capsid,… »
A humanized monoclonal antibody directed against parathyroid hormone-related protein (PTH-rP). As a poly-hormone with diverse biological roles, PTH-rP is expressed by normal… »
A recombinant monoclonal antibody directed against colon cancer (CC) epitopes, tumor-associated glycoprotein 72 (TAG72). TAG72 is expressed in gastric, breast, pancreatic,… »
A second-generation murine monoclonal antibody based on monoclonal antibody B72.3 and directed against tumor-associated glycoprotein 72 (TAG72). TAG72 is expressed in… »
A second-generation murine monoclonal antibody based on the monoclonal antibody B72.3 and directed against tumor-associated glycoprotein 72 (TAG72). TAG72 is expressed… »
A second-generation murine monoclonal antibody based on the antibody B72.3 that is directed against tumor-associated glycoprotein 72 (TAG72). TAG72 is expressed… »
A humanized CH2 domain-deleted second-generation monoclonal antibody based on the antibody B72.3 that is directed against tumor-associated glycoprotein 72 (TAG72). TAG72… »
A mouse anti-human CD19 monoclonal antibody (MoAb). CD19 as well as CD22 are cell surface antigens present on a majority of B… »
A monoclonal antibody directed against carcinoembryonic antigen (CEA) which is expressed by most gastrointestinal carcinomas and by some breast, lung and ovarian… »
A humanized monoclonal antibody targeting glycolipids, with potential immunomodulating and antineoplastic activity. Upon administration, monoclonal antibody CEP-37250/KHK2804 targets and binds to a… »
A substance being studied in the treatment of cancer. It binds to a molecule called GD2, which is found in greater than… »
A murine IgG2 monoclonal antibody against the tumor-associated antigen 17-1A. Administration of monoclonal antibody CO17-1A (Mab C017-1A) elicits an antibody-dependent cell-mediated… »
A recombinant immunoglobulin antibody directed against the tumor-associated antigen carcinoembryonic antigen (CEA). CEA is a cell surface glycoprotein expressed at high levels… »
A recombinant immunoglobulin antibody directed against the tumor-associated carcinoembryonic antigen (CEA). CEA is a cell surface glycoprotein expressed at high levels in… »
A murine IgG2a monoclonal antibody directed against a 48 kDa antigen expressed on the cell surface of normal and malignant gastrointestinal… »
A monoclonal antibody that inhibits binding of vascular endothelial growth factor to its receptor, thereby inhibiting angiogenesis and tumor growth. »
A murine IgG1 monoclonal antibody directed against the human transferrin (Tf) receptor. Monoclonal antibody E2.3 binds to the Tf receptor, blocking the… »
A human IgG2kappa monoclonal antibody specific for the epidermal growth factor receptor (EGFR). Monoclonal antibody E7.6.3 binds to the EGFR, blocking the… »
A murine monoclonal antibody (MoAb) against human fibroblast activation protein (FAP). FAP is a 95 kDa cell surface glycoprotein and an inducible… »
A class of vaccines that consist of anti-idiotype monoclonal antibodies against the tumor-associated antigen disialoganglioside GD2 with potential antineoplastic activity. Vaccination… »
A humanized monoclonal antibody directed against tumor-associated glycoprotein 72 (TAG72). TAG72 is expressed in gastric, breast, pancreatic, colorectal, and ovarian… »
A humanized CH2 domain-deleted second-generation monoclonal antibody based on the antibody B72.3 that is directed against tumor-associated glycoprotein 72 (TAG72). TAG72… »
An immunotoxin consisting of the murine anti-CD19 monoclonal antibody HD37 conjugated to a deglycosylated ricin A chain (dgA) via the linking molecule… »
A murine monoclonal antibody with potential antineoplastic activity. Monoclonal antibody HeFi-1 binds to CD30, a cell surface antigen found on mitogen-activated B-cells… »
A recombinant monoclonal antibody directed against the human suppressor-cytotoxic T-cell subset and designed to deplete circulating Leu 2A-positive lymphocytes. The antigen… »
A humanized monoclonal antibody directed against the Lewis Y antigen, a tumor-associated epithelial antigen, with potential antineoplastic activity. Following binding, monoclonal antibody… »
A humanized monoclonal antibody directed against alpha fetoprotein with potential antineoplastic activity. Upon administration, monoclonal antibody HuAFP31 (mAb HuAFP31) binds to and… »
A humanized monoclonal antibody directed against MUC1, a mucin glycoprotein overexpressed in breast and other carcinomas. Monoclonal antibody HuHMFG1 stimulates antibody-dependent… »
A humanized monoclonal antibody (MoAb) against the external domain of the Prostate-specific membrane antigen (PSMA), overexpressed in the malignant prostate and its… »
A substance being studied in the treatment of myelodysplastic syndromes and some types of leukemia. It binds to CD33, a protein on… »
A humanized monoclonal antibody directed against vascular endothelial growth factor (VEGF), a pro-angiogenic cytokine. HuMV833 has been shown to decrease the… »
A humanized monoclonal antibody directed against the pancreatic cancer antigen MUC1 with potential antineoplastic activity. Monoclonal antibody HuPAM4 (mAb HuPAM4) binds to… »
A rat monoclonal antibody that inhibits Epidermal Growth Factor Receptor (EGFR), targeting tumor cells expressing the wild-type EGFR and EGFRvIII. »
An anti-carcinoembryonic antigen (anti-CEA) murine monoclonal immunoglobulin G (IgG) with potential antineoplastic activity. CEA is overexpressed in several cancer cell types,… »
Monoclonal recombinant antibody J591 (mAb HuJ591) recognizes the extracellular domain of prostate specific membrane antigen (PSMA), a cell surface peptidase highly expressed… »
A murine IgG2a monoclonal antibody with potential antineoplastic activity. Monoclonal antibody L6 binds to the L6 antigen, a cell surface glycoprotein overexpressed… »
A murine monoclonal antibody (MoAb) IgG2a, LL2. MoAb LL2 recognizes CD22, a B-lymphocyte-restricted antigen expressed as a cytoplasmic protein in progenitor B… »
A murine IgG2a monoclonal antibody directed against the HLA-Dr10 protein, a cell surface marker present on over eighty percent of lymphoma… »
A recombinant murine monoclonal antibody directed against a human class II molecule variant found on the surfaces of normal and neoplastic human… »
A chimeric murine-human anti-CD4 monoclonal antibody that down regulates T-helper-inducer function. Clinical Trails: Multiple Sclerosis. »
A panadenocarcinoma murine monoclonal antibody (MoAb) with potential antineoplastic activity. MoAb m170 recognizes MUC-1 antigen present on the surface of many… »
A murine IgG2a monoclonal antibody that targets CD33, a 67-kD cell surface glycoprotein expressed on myeloid leukemia cells. »
A monoclonal antibody used to purge leukemia cells from bone marrow. »
A bispecific antibody containing a patented Trigger antibody and a humanized antibody that targets TAG-72. TAG-72 is overexpressed in a variety… »
The F(ab)2 fragment of Me1-14, a murine IgG2a monoclonal antibody directed against proteoglycan chondroitin sulfate-associated protein expressed by gliomas and melanomas. … »
An Fc-domain optimized, humanized monoclonal antibody directed against cancer stem cells (CSCs), with potential immunomodulating and antineoplastic activities. After binding of monoclonal… »
A murine monoclonal antibody directed against of the beta subunit of interleukin-2 receptor (IL-2R), expressed on resting T-lymphocytes, natural killer (NK) cells,… »
An immunotoxin of monoclonal antibody (MoAb) RFB4 covalently linked to a single deglycosylated ricin toxin A-chain (dgA), originated from castor beans. MoAb… »
A murine IgG monoclonal antibody against the external domain of the prostate-specific membrane antigen (PSMA), overexpressed in the malignant prostate and its… »
The F(ab)2 fragment of monoclonal antibody (MoAb) MX35 that recognizes a 95 kD glycoprotein with homogeneous distribution on 80% of ovarian tumor… »
A synthetic immunotoxin consisting of the murine monoclonal antibody N901 conjugated with toxin-blocked ricin (BR). Monoclonal antibody N901-BR binds to CD56,… »
A mouse monoclonal IgG3 antibody that reacts with the cytoplasm and cell surface of colonic adenocarcinoma and shows restricted normal tissue… »
A recombinant monoclonal antibody (OVB3) directed against human ovarian cancer linked with an exotoxin derived from the bacterium Pseudomonas aeruginosa. The… »
The Monoclonal Antibody Production Shared Resource is responsible for monoclonal antibody generation and production, provides other antibody-related products and services to support… »
An IgG murine monoclonal antibody directed against the ganglioside GD3 glycolipid, located in the cell membranes of some tumor cells. Monoclonal… »
A chimeric monoclonal antibody directed against a primate-restricted N-linked carbohydrate epitope (glycotope) expressed on various human carcinomas with potential antineoplastic activity. Following… »
A murine monoclonal antibody directed against the human epidermal growth factor receptor (EGFR). Monoclonal antibody RG 83852 binds to the EGFR,… »
A humanized monoclonal antibody targeting the CD40 antigen with potential antineoplastic activity. CD-40, an integral membrane protein found on the surface of… »
A genetically-engineered, chimeric mouse-human, anti-CD30 monoclonal antibody with potential antineoplastic activity. Monoclonal antibody SGN-30 specifically binds to the receptor CD-30, a member… »
A murine monoclonal antibody (MoAb) with application in Immunotherapy and radioimmunodetection in T-cell malignancies. MoAb T101 recognizes a 65kD glycoprotein, CD5 antigen,… »
A synthetic mouse monoclonal antibody which targets CD5+ lymphocytes. Monoclonal antibody T101 may be used in the immunotherapy of T-cell… »
A monoclonal antibody (MOAB) directed against an antigen expressed by colorectal cancer cells. »
Monoclonal antibodies used for clinical diagnosis »
A condition in which a higher-than-normal number of identical B cells are found in the blood. People with monoclonal B-cell lymphocytosis may… »
A laboratory test result indicating the presence of an abnormally high level of monoclonal immunoglobulins in the blood or urine. »
A benign condition in which there is a higher-than-normal level of a protein called M protein in the blood. Patients with monoclonal… »
A plasma cell neoplasm characterized by the deposition of immunoglobulin in tissues, resulting in impaired organ function. It includes the following entities:… »
An antibody found in unusually large amounts in the blood or urine of people with multiple myeloma and other types of plasma… »
The determination of the amount of monoclonal protein present in a sample. »
A fusion protein containing a modified form of human T-cell receptor (TCR) specific for the gp100 antigen and fused to an anti-CD3… »
A type of immune cell that is made in the bone marrow and travels through the blood to tissues in the body… »
The determination of the amount of monocyte chemotactic protein 1 present in a sample. »
The determination of the number of monocytes in a blood sample. »
Monocyte Differentiation Antigen CD14 (375 aa, 40 kD) is a cell fate protein that is encoded by the human CD14 gene and… »
Monocytes are a class of phagocytes involved in non-specific immune defense that develop into macrophages. In plasma, monocytes ingest and destroy bacteria,… »
The determination of the ratio of monocytes compared to leukocytes in a blood sample. The measurement may be expressed as a ratio… »
Monocytes made cytotoxic by ex vivo incubation with cytokines, especially interferon-gamma. AKM cells are used for adoptive immunotherapy in cancer patients. … »
The determination of the ratio of monocytes compared to macrocytes present in a sample. The measurement may be expressed as a ratio… »
The determination of the ratio of monocytes compared to total cells present in a sample. The measurement may be expressed as a… »
Monocytic leukemia responding to treatment and not proliferating »
A lymphocyte derived most often from a pre-germinal center B cell, less often from a post-germinal center B cell. It is characterized… »
The determination of the amount of monocytoid cells present in a sample. »
The determination of the ratio of the monocytoid cells compared to total cells present in a sample. The measurement may be expressed… »
A teratoma that arises from the testis. It is composed exclusively of one of the following tissue types endoderm, ectoderm, or… »
A first generation monoethanolamine with antihistaminic property. Ethanolamine competes with free histamine for binding at the histamine (H)-1 receptor thereby acting as… »
A synthetic, colorless gas that is insoluble in water and soluble in organic solvents. It is used primarily in the production of… »
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (978 aa, ~106 kDa) is encoded by the human MTHFD1L gene. This protein is involved in the modulation… »
A modified form of acetylcysteine that is a metabolite of 1,3-butadiene and may be found in the urine of smokers. »
A molecule that can join with other identical monomers to form a larger structure called a polymer. »
A green-fluorescent dye that has the ability to penetrate apoptotic cells because of permeability changes associated with the loss in asymmetry of… »
Molécula que se puede unir con otros monómeros idénticos para formar una estructura mayor llamada polímero. »
A clonal B-cell lymphoproliferative disorder arising as a result of post-transplant immunosuppression therapy. It is characterized by destructive infiltration of lymph nodes… »
A primary small intestinal T-cell non-Hodgkin lymphoma of intraepithelial T-lymphocytes. It is characterized by the presence of small to medium sized… »
A malignant neoplasm that is composed of spindle cells that contain one or more keratins. »
A clonal lymphoproliferative disorder arising as a result of post-transplant immunosuppression therapy. It is characterized by destructive infiltration of lymph nodes and… »
A clonal T-cell lymphoproliferative disorder arising as a result of post-transplant immunosuppression therapy. It is characterized by destructive infiltration of lymph nodes… »
An electrocardiographic finding of a ventricular tachycardia in which the QRS complexes have a uniform morphology. »
A painful asymmetric asynchronous sensory and motor peripheral neuropathy involving isolated damage to at least 2 separate nerve areas; associated with (but… »
Possessing a single nucleus. »
A mixture of cells possessing a single nucleus, including monocytes and lymphocytes; blood leukocytes from which granulocytes have been separated and… »
La mononucleosis infecciosa, es una infección causada por el virus de Epstein-Barr. El virus se disemina a través de la saliva… »
A set of genetic loci where each locus contains either a mononucleotide (single base pair) repeat or a dinucleotide (two nucleotide subunits)… »
A set of genetic loci where each locus contains a mononucleotide (single base pair) repeat sequence. Changes in the length of the… »
Occurring in or characterized by only one phase or stage. »
A synovial sarcoma characterized by the presence of an epithelial or a spindle cell component only. »
A modified form of lipid A, the biologically active part of Gram-negative bacterial lipopolysaccharide (LPS) endotoxin, and a Toll-like receptor 4 (TLR4)… »
A carbohydrate which cannot be reduced to smaller units by hydrolysis; it is the simplest structural form of a carbohydrate. »
A glycosphingolipid containing a sialic acid residue found in neuronal cell membranes, with potential neuroprotective and neuroregenerative activities. Upon administration, monosialotetrahexosylganglioside, also… »
The determination of the amount of monosodium urate crystals present in a sample. »
A chromosomal abnormality consisting of the absence of one chromosome from the normal diploid number. »
A chromosomal abnormality consisting of the absence of a copy (homolog) of chromosome 13. »
A rare syndrome that is characterized by the partial deletion of the long arm of chromosome 13. Signs and symptoms include low… »
A cytogenetic aneuploidy abnormality that refers to the presence of one chromosome 5 only. It is associated with the development of refractory… »
A chromosomal abnormality consisting of the absence of one of the copies of chromosome 7 in somatic cells. »
Therapy that uses one type of treatment, such as radiation therapy or surgery alone, to treat a certain disease or condition. In… »
The type of ubiquitin modification determines the functional consequences for the modified protein. Monoubiquitination does not serve as a proteasome targeting signal,… »
A class of dietary fatty acids containing one double bond. »
Gas venenoso que no tiene olor ni color. Lo emite la quema de combustible (como en el caso del escape de los… »
An water-in-oil (w/o) emulsion with immunomoadjuvant activity. Montanide ISA 51 VG appears to act by enhancing the immune system's cytotoxic T-lymphocyte (CTL)… »
A proprietary adjuvant, applicable for water-in-oil (W/O; 30/70 v/v) vaccine emulsion, with potential immunoadjuvant activity. Montanide ISA 720 is made of natural… »
A mixture of oil and water that is combined with a specific antigen to boost the immune response to that antigen. … »
Mezcla de aceite y agua que se combina con un antígeno específico para estimular la respuesta inmunitaria a este antígeno. Está en… »
A computing method involving many similar individual, yet randomly differing, calculations. The individual calculations differ due to the introduction of random numbers… »
The active ingredient in a drug used to treat symptoms of asthma, such as trouble breathing, tight chest, wheezing, coughing, and runny… »
Ingrediente activo de un medicamento que se usa para tratar los síntomas del asma; por ejemplo, dificultad para respirar, sensación del pecho… »
Medicamento que se usa para tratar los síntomas del asma; por ejemplo, dificultad para respirar, sensación del pecho apretado, silbidos, la tos… »
A drug used to treat symptoms of asthma, such as trouble breathing, tight chest, wheezing, coughing, and runny nose. Montelukast sodium blocks… »
A group of small sebaceous glands that secrete into the areolae of the mother's breast to lubricate the nipple during breastfeeding. … »
One of the 12 divisions of a year as determined by a calendar. It corresponds to the unit of time of approximately… »
An imputed date that includes the month and day of observation. »
Any of the 12 major divisions of the year, each lasting approximately 30 days. »
The month and year of interest. »
A change in disposition or state of mind. »
A category of psychiatric disorders which have as their most predominant feature a disturbance in mood. »
Most people feel sad or irritable from time to time. They may say they're in a bad mood. A mood disorder is… »
A phosphodiesterase inhibitor which inhibits platelet aggregation. Formerly used as an antineoplastic. »
An abbreviation for a chemotherapy combination used alone or with radiation therapy to treat Hodgkin lymphoma. It includes the drugs mechlorethamine hydrochloride,… »
Abreviatura del nombre de una quimioterapia combinada que se usa sola o con radioterapia para tratar el linfoma de Hodgkin. Contiene los… »
An abbreviation for a chemotherapy combination used alone or with radiation therapy to treat Hodgkin lymphoma. It includes the drugs mechlorethamine hydrochloride,… »
A non-cross resistant regimen in which half of the MOPP regimen is administered with half of the ABV regimen and is used… »
An alternating, non-cross resistant regimen consisting of mechlorethamine, vincristine, prednisone and procarbazine (MOPP) followed by doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD), used… »
A monoclonal antibody being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can… »
Anticuerpo monoclonal en estudio para el tratamiento de algunos tipos de cáncer. Los anticuerpos monoclonales se producen en el laboratorio y pueden… »
Having to do with beliefs about what is right and wrong in terms of how people behave. Also called ethical. … »
Relacionado con las creencias sobre lo que es correcto o equivocado en la conducta de las personas. También se llama ético. … »
A genus of Gram-negative bacteria in the Moraxellaceae family ocurring as short rods, coccobacilli or diplococci. »
A species of aerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is oxidase positive, negative for urease,… »
A species of aerobic, Gram negative, rod shaped, bacteria assigned to the phylum Proteobacteria. This species is oxidase positive, nonmotile, and requires… »
A species of aerobic, Gram negative, cocci shaped, bacteria assigned to the phylum Proteobacteria. This species is positive for oxidase, catalase, butyrate… »
A species of gram-negative, aerobic, oxidase-positive diplococcus bacteria within the phylum Proteobacteria that causes upper respiratory tract infections, particularly in immunocompromised… »
A species of aerobic, Gram negative, cocci shaped bacteria assigned to the phylum Proteobacteria. This species is oxidase positive, nonmotile, sensitive to… »
A species of aerobic, Gram negative, coccobacilli shaped bacteria assigned to the phylum Proteobacteria. This species is oxidase and catalase positive, urease… »
A species of aerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is nonmotile, nonhemolytic, oxidase and catalase… »
A species of aerobic, Gram negative, cocci shaped bacteria assigned to the phylum Proteobacteria. This species is oxidase and catalase positive, does… »
A species of aerobic, Gram negative, cocci shaped bacteria assigned to the phylum Proteobacteria. This species is oxidase and catalase positive, nonmotile… »
A taxonomic family of bacterium in the phylum Proteobacteria that includes the genera Moraxella, Acinetobacter and Psychrobacter, among others. »
The condition of weighing two, three, or more times the ideal weight, so called because it is associated with many serious and… »
Refers to having a disease or a symptom of disease, or to the amount of disease within a population. Morbidity also refers… »
Se refiere a la presentación de una enfermedad o síntoma de una enfermedad, o a la proporción de enfermedad en una… »
A genus of Paramyxovirinae which includes Measles Virus »
MORC family CW-type zinc finger protein 3 (939 aa, ~107 kDa) is encoded by the human MORC3 gene. This protein is involved… »
This gene is involved in binding to both RNA and nuclear matrix proteins. »
Human MORC3 wild-type allele is located in the vicinity of 21q22.13 and is approximately 66 kb in length. This allele, which encodes… »
Los animales salvajes suelen huir de las personas. Sin embargo, pueden atacar si se sienten amenazados, si están enfermos, si protegen a… »
A morphologic finding indicating the presence of more than five mitotic figures per fifty high power fields in a cellular infiltrate. … »
A time period that includes one-half of the total number of days plus at least one more. »
Un moretón o hematoma es una marca en la piel causada por la presencia de sangre atrapada debajo de la superficie de… »
Ciencia de la forma y la estructura de los organismos (plantas, animales y otras formas de vida). »
A genus of facultatively anaerobic, Gram negative, rod shaped bacterium in the phylum Proteobacteria and the family Enterobacteriaceae. »
A species of oxidase-negative Gram-negative bacillus bacteria in the Enterobacteriaceae family with anaerobic respiration. »
An indication that a study subject was near death when it was euthanized. »
The hydrochloride salt form of moricizine, a phenothiazine analog with class I antiarrhythmic activity. Moricizine hydrochloride blocks the rapid flow of sodium… »
A second-line antituberculosis agent. »
A tropical shrub. An extract from the fruit is being studied as a treatment for cancer, and extracts from the fruit, leaves,… »
Arbusto tropical. Un extracto de su fruto está en estudio para el tratamiento de cáncer; asimismo, los extractos del fruto, la hojas… »
An extract prepared from the fruit of Morinda citrifolia, a plant that yields various herbal preparations. Morinda citrifolia fruit juice has antioxidant… »
A religious group that identifies with the beliefs and culture of the Latter-Day Saint movement. »
The nausea and vomiting that accompanies early pregnancy. »
An involuntary, primal response in the neonate to loud noise or the feeling of falling. The response is characterized by the infant's… »
A country in northern Africa, bordering the North Atlantic Ocean and the Mediterranean Sea, south of Spain and between Algeria and Western… »
A heterocyclic biguanidine with activity against influenza and other viral infections. Although its mechanism of action is not fully known the effects… »
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu… »
The determination of the amount of morphine present in a sample. »
A drug used to treat moderate to severe pain. It binds to opioid receptors in the central nervous system and some other… »
A sustained-release tablet formulation containing the sulfate salt of the opiate alkaloid morphine with analgesic activity. Morphine binds to and activates the… »
The process of shape formation: the processes that are responsible for producing the complex shapes of adults from the simple ball of… »
An antisense oligonucleotide modified to be more stable than RNA. While morpholinos have standard nucleic acid bases, those bases are bound to… »
A semisynthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin. As an antineoplastic agent, morpholinodoxorubicin is more potent than doxorubicin. Similar… »
A microscopic finding that relates to the architectural patterns of a normal or abnormal cellular population in a tissue specimen. »
A light microscopic finding that describes the cellular characteristics and architectural patterns of cell populations in a tissue sample. »
The science of the form and structure of organisms (plants, animals, and other forms of life). »
A subject domain utilized for the submission of information encompassing and representing data, vocabulary or records related to morphology findings. »
A rare autosomal recessive lysosomal storage disease characterized by abnormal skeletal developments, dwarfism, heart disorders, and central nervous system deficits. »
Término que se refiere al estado de ser mortal (destinado a morir). En el campo de la medicina, es un… »
Refers to the state of being mortal (destined to die). In medicine, a term also used for death rate, or the number… »
A visual representation of the national cancer burden. These maps display cancer mortality data by county and state economic regions across… »
A morphologic finding indicating the replacement of part of the glandular endometrial epithelium by nodular structures that contain non-keratinizing squamous cells. … »
Human MOS wild-type allele is located within 8q11 and is approximately 1 kb in length. This allele, which encodes proto-oncogene serine/threonine-protein kinase… »
An individual containing two or more populations of genetically different cells that arose from a single zygote. »
The occurrence of 2 or more cell lines with different genetic or chromosomal make-up, within a single individual or tissue. »
A proprietary information management system designed as a vendor-neutral platform that collects radiation oncology and medical oncology patient data into a single… »
A question about an individual's most bothersome symptom attributed to steroid use. »
A response indicating that something happens or happened most of the time. »
Nearest to the present. »
The most recent occurrence of angina pectoris. »
The most recent occurrence of heart failure. »
The formula to calculate body surface area as described by RD Mosteller. It is mathematically defined as: BSA (m^2) = ([Height(cm) x… »
A predominant feeling of concurrence. »
A predominant feeling of opposition. »
A humanized monoclonal antibody directed against the respiratory syncytial virus (RSV) fusion glycoprotein (F-protein), with activity against RSV. Motavizumab targets and binds… »
An orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR),… »
The orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib selectively targets and inhibits vascular endothelial… »
A substance being studied in the treatment and diagnosis of some types of cancer. It builds up in some cancer cells, which… »
A substance that is being studied in the treatment of cancer using photodynamic therapy. It belongs to the family of drugs called… »
Sustancia en estudio para el tratamiento de cáncer en que se usa la terapia fotodinámica. Es un tipo de metalotexaferina. También se… »
The mother of your spouse. »
The circuit board that contains most of the processor units. »
Mothers against decapentaplegic homolog 1 (465 aa, ~52 kDa) is encoded by the human SMAD1 gene. This protein plays a role in… »
Mothers against decapentaplegic homolog 2 (467 aa, ~52 kDa) is encoded by the human SMAD2 gene. This protein plays a role in… »
Regulated by TGF-beta receptors, Mothers Against Decapentaplegic Homolog 3 is an effector of the TGF-beta response. MADH3 is associated with and… »
The SMAD4 tumor suppressor protein specifically recognizes an eight base pair palindromic DNA sequence and is critical for transmitting TGFB, and related… »
An herbal remedy containing parts of Leonurus cardiaca, a perennial plant in the mint family Lamiaceae. The parts used are the aerial… »
Capacidad de la célula para moverse. »
A device designed to signal the presence of excess motion in a system. »
An artifact resulting from movement of the object being imaged during the imaging sequence. »
Disorder caused by motion, as sea sickness, train sickness, car sickness, air sickness, or SPACE MOTION SICKNESS. It may include nausea, vomiting… »
The psychological feature that arouses an organism to action toward a desired goal; the reason for the action; that which gives purpose… »
A question about whether an individual's motivation is or was lower when fatigued. »
The evolution of physical movement over an individual's lifespan. »
A device designed to convert energy into mechanical motion. »
A device consisting of a motor and accessory parts designed to power a machine. »
The presence of an alteration in the ability to move one's body or any body parts in accordance with one's intent. … »
An efferent neuron that sends impulses from the central nervous system to skeletal muscles. »
Motor neuron and pancreas homeobox protein 1 (401 aa, ~41 kDa) is encoded by the human MNX1 gene. This protein plays a… »
A type of disease in which the nerve cells in the brain that act on muscle cells break down and stop… »
A pin that is formed as a rolled sheet and acts to provide a retaining force on the part through which it… »
Every year thousands of people in the U.S. die from motor vehicle crashes. Trying to prevent these crashes is one part of… »
An aromatic retinoic acid with antikeratonizing activity. Motretinide is used as a topical agent in the treatment of acne. »
A drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It… »
Medicamento que se usa para tratar la fiebre, la hinchazón, el dolor y el enrojecimiento al impedir que el cuerpo elabore sustancias… »
Irregularly shaped, patchy discolorations in the skin. »
A structural device designed to facilitate the attachment of one object to another. »
The area in the United States comprised of the following states: Idaho, Wyoming, Colorado, Utah, Nevada, New Mexico and Arizona. »
A census division of the United States consisting of Arizona, Colorado, Idaho, Montana, Nevada, New Mexico, Utah, and Wyoming. »
Any of numerous species of small rodents belonging to the genus Mus and various related genera of the family Muridae. »
Usually refers to white fat unless specified as brown. »
A melanoma composed of cells with rounded nuclear and cytoplasmic contours (epithelioid cytology) that lacks melanin pigment. »
A melanoma composed of cells with elongated nuclear and cytoplasmic contours (spindle cell cytology) that lacks melanin pigment. »
Intermediate grade glial neoplasm characterized by increased cellularity, nuclear pleomorphism, mitoses, and variable vascular endothelial proliferation without tumor necrosis. »
An oligoastrocytoma increased cellularity, cytologic atypia, and increased mitotic activity. Often there is also an increased vascularity and tumor necrosis. … »
Oligodendroglioma with greater cellularity, cytologic atypia, and mitotic activity. Similar to astrocytic glial tumors, these higher grade lesions show increased vascularity… »
Any of the mouse anatomical structures consisting of similarly specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships, performing… »
A clonal proliferation of melanocytes without significant potential for locally aggressive growth or metastasis. »
Similar to the human CGAP. The overall goals of the m-CGAP are: a comparative assessment of mouse cancer stages with those of… »
Cuboidal to columnar epithelium with prominent rounded nuclei. »
Collection of multiple empty acini lined by a single layer of cuboidal or flattened epithelium. Papillary projections may be present. »
An infiltrating Choroid Plexus Tumor with nuclear pleomorphism, increased mitoses, and often tumor necrosis. »
A non-invasive Choroid Plexus Tumor with a papillary architecture. »
A neoplasm or the cellar region presumed to be derived from Rathke's pouch epithelial cells. Often cystic with a well demarcated… »
Lymphocytic neoplasms that arise in the skin. »
An organization of mouse disorders based on the body site affected. »
A resource of the Jackson lab, provides integrated access to data on the genetics, genomics, and biology of the laboratory mouse. … »
Giant Cell Glioblastoma is a histological variant of Glioblastoma with a predominance of bizarre, multinucleated giant cells, an occasionally abundant stromal reticulin… »
A high grade glial neoplasm consisting chiefly of undifferentiated anaplastic cells of glial origin that show marked nuclear pleomorphism. The diagnosis… »
A vaccine consisting of a plasmid DNA encoding the murine melanoma-associated antigen gp100. Upon administration, expressed gp100 antigen may stimulate a cytotoxic… »
Lesion is composed predominantly of granulocytic and/or relatively undifferentiated non-lymphoid hematopoietic cells »
combination of hepatocytes and bile duct epithelium lesions »
Severe dysplasia, disruption of normal architecture, increased mitotic activity, loss of cellular polarity »
Increased size, compression of adjacent tissue. Often form branching tubular structures, enlarged nuclei with prominent nucleolus. »
Type C retroviruses that cause leukemia in mice. Includes the Abelson, AKR, Friend, Moloney, Gross, and other leukemia viruses. »
A clonal proliferation of melanocytes with significant potential for locally aggressive growth or metastasis. »
Type B retrovirus. Etiologic agent of mouse mammary tumors. Transmitted horizontally through the lactating mammary gland and vertically through the… »
Cells exhibit features of mast cells; Lesion has characteristic cytology: uniform, closely packed cells with round nuclei and clear abundant cytoplasm with… »
Invasive embryonal neoplasm of the cerebellum showing neuronal differentiation histologically (Homer-Wright and/or Flexner-Wintersteiner rosette formation) by immunohistochemistry (synaptophysin, chromogranin, or NSE expression),… »
An increase in the number of melanocytes for a given anatomic site. »
Melanocytic neoplasms and are not clearly benign or malignant. Melanocytic neoplasms that occasionally but infrequently exhibit malignant characteristics fall into this… »
A benign melanocytic neoplasm composed of epithelioid melanocytes with a low nuclear/cytoplasmic ratio and usually containing extensive pigment in non-albino mice. … »
Neoplasms of the meningeal coverings, typically well demarcated with pushing encapsulated borders. A wide range of architectures are possible, but psammoma… »
MIN NOS (Not Otherwise Specified) is a mammary intraepithelial neoplasm without established or known biological potential »
The use of special strains of mice to study a human disease or condition, and how to prevent and treat it. … »
A neoplastic disease of a mouse with clinical features sufficiently similar to those of a human cancer to serve as a test… »
A program to develop and refine experimental models that reflect the etiology and progression of human cancer. »
Comment: Leukemia in which neoplastic cells are well differentiated; less than 20% immature forms/blasts in hematopoietic tissue »
Comment: may be designated as having features of a named human MDS; Morphologic dysgranulopoiesis, dyserythropoiesis, and/or dysplastic megakaryocytes (with or without increased… »
Bone marrow cells are less than 50% erythroid cells; Bone marrow cells are less than 50% megakaryocytic cells; Comprised predominantly of granulocytic… »
Comment: Leukemia in which neoplastic cells are moderately differentiated and neutrophilic; With a neutrophilic component; Without a monocytic component; greater or equal… »
Comment: Intended to encompass diseases more closely related to human myelodysplastic/myeloproliferative or myeloproliferative diseases than to human myelodysplastic syndromes. Myeloid proliferations… »
Comment: Leukemia in which neoplastic cells are moderately differentiated including both neutrophilic and monocytic cells; With a monocytic component; With a neutrophilic… »
Comment: Intended to be used for disorders of genetically engineered mice that are not characterized by increased blood counts; Genetic »
Bone marrow, if involved, contains at least focal areas in which hematopoiesis is preserved; Lesion is - invasive into surrounding tissues and/or… »
A non-lymphoid hematopoietic neoplasm that diffusely involves hematopoietic tissue, generally both the spleen and bone marrow; Comment: Additional descriptor may be applied… »
Based on IC of Rodent Tumors: The Mouse »
Flat epithelial lesions composed of tall columnar cells with basally located nuclei and abundant supranuclear mucin. The nuclei are small and round… »
These epithelial lesions have a papillary, micropapillary or basally pseudostratified architecture, but are otherwise identical to PanIN-1A. »
These mucinous epithelial lesions may be flat or papillary. These lesions must have some nuclear abnormalities including some loss of polarity, nuclear… »
These are usually papillary or micropapillary, however, they may rarely be flat. True cribriforming, budding off of small clusters of epithelial cells… »
Variant of Ependymoma characterized by well formed papillae. Tumor cell processes abutting capillaries are usually GFAP-positive. »
The Mouse Pathology Shared Resource provides histologic and hematopoietic research support services to Cancer Center investigators and others studying the pathogenesis and… »
Invasive embryonal neoplasm of the pineal gland showing neuronal differentiation histologically (Homer-Wright and/or Flexner-Wintersteiner rosette formation) by immunohistochemistry (synaptophysin, chromogranin, or NSE… »
Frequent in some GEM and mice infected with acutely transforming MuLV; Necropsy findings: Splenomegaly, generalized lymphadenopathy, usually with extensive spread to liver,… »
A vaccine consisting of a plasmid DNA encoding the murine prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic… »
Inflammatory process characterized by infiltration of inflammatory cells into prostatic stromal and glandular elements. »
Proteins found in any species or strain of mouse. »
An agarose matrix containing mouse renal adenocarcinoma (RENCA) cells, with potential antineoplastic activity. The agarose-agarose macrobeads consist of two spherical agarose layers;… »
A rare somatostatin-secreting tumor of pancreatic delta cells associated with diabetes mellitus or abnormal glucose tolerance. »
Neuron is also used as a concept under brain in this hierarchy. Both Brain and Spinal Cord neurons are CNS… »
Breeds of mice utilized for biological research. »
IL-15 transgenic mouse, CD3+, resembles LGL leukemia. »
A component of CGAP. »
Your mouth is one of the most important parts of your body. Any problem that affects your mouth can make it hard… »
A clinical term that indicates the presence of a white patch on the mucous membrane in the mouth which cannot be characterized… »
A necrotic process affecting the tissues of the mouth. »
A question about an individual's mouth or throat sores at its worst. »
A break in the mucosal surface of the oral cavity. »
A solution or suspension intended for oral administration, for its deodorizing or antiseptic effects in the oral cavity. Usually, the mouthwash is… »
A chimeric antigen receptor gene derived from the murine monoclonal antibody MOv18 that binds to folate-binding protein (FBP). Peripheral blood lymphocytes… »
A recombinant engineered chimeric gene derived from the murine gene encoding the variable region of monoclonal antibody MOv18 against folate-binding protein, which… »
Peripheral blood lymphocytes (PBL) transfected to express MOv have been designed for possible use in autologous adoptive cellular immunotherapy of ovarian adenocarcinomas… »
A standardized rating scale developed and copyrighted by the Movement Disorders Society in 2008 and published in the journal Movement Disorders… »
Imagine if parts of your body moved when you didn't want them to. If you have a movement disorder, you experience these… »
During examination of the newborn infant, the examiner looks for symmetric movement of the lip corners. Movement of the lip corners is… »
Proceso en que se usan ciertas substancias para provocar el movimiento de células madre desde la médula ósea hacia la… »
A process that removes water or volatile solvents from an agitated or tumbling bed of solids by relying on heat transfer from… »
The use of a rotary drum, belt, or other moving filter to purify a slurry. »
A question about whether an individual has or has been moving or speaking so slowly that other people could have noticed. … »
A rare autosomal dominant syndrome caused by mutations in the ZEB2 gene. It is characterized by mental retardation, and a distinctive facial… »
A semisynthetic oxa-beta-lactam antibiotic, with antibacterial activity used mainly against gram-negative aerobic bacteria. Replacing the beta-lactam sulfur atom for an oxygen atom… »
A parenteral oxacephem antibiotic with an oxygen molecule substituted for the sulfur atom in the beta-lactam nucleus. Moxalactam is a thrid-generation cephalosporin… »
A recombinant immunotoxin consisting of the Fv portion of the anti-CD22 antibody covalently fused to a 38 KDa fragment of Pseudomonas exotoxin-A… »
In traditional Chinese medicine, a type of heat therapy in which an herb is burned on or above the skin to warm… »
En la medicina tradicional china, un tipo de terapia con calor en el que se quema una hierba sobre la piel o… »
A drug used to treat bacterial infections. It is a type of fluoroquinolone. Also called Avelox and moxifloxacin hydrochloride. »
A drug used to treat bacterial infections. It is a type of fluoroquinolone. Also called Avelox and moxifloxacin. »
Medicamento que se usa para tratar infecciones bacterianas. Es un tipo de fluoroquinolona. También se llama Avelox y hidrocloruro de moxifloxacino. … »
A rare inherited vascular disorder characterized by constriction of arteries at the base of the brain, resulting in the formation of collateral… »
Expression of a fusion protein that results from a translocation involving the human MOZ gene and various fusion gene partners. The fusion… »
A country in southeastern Africa, bordering the Mozambique Channel, between South Africa and Tanzania. »
A non-peptidomimetic, water soluble, cyclic urea that is a selective inhibitor of HIV-1 protease. »
A drug used before autologous stem cell transplantation in patients with non-Hodgkin lymphoma or multiple myeloma. Mozobil is given together with granulocyte-colony… »
Sustancia que se usa para los pacientes de linfoma no Hodgkin o mieloma múltiple antes de un trasplante de células madre… »
A regimen consisting of mitoxantrone and prednisone used to treat metastatic hormone-refractory prostate cancer. »