Medicine

A regimen consisting of melphalan and prednisone used as induction treatment for multiple myeloma. »
A substance being studied in the treatment of some types of cancer. It may block certain proteins involved in cancer cell growth… »
Sustancia en estudio para el tratamiento de algunos tipos de cáncer. Podría impedir la acción de ciertas enzimas que participan en la… »
A regimen consisting of melphalan, prednisone and bortezomib used for the treatment of multiple myeloma. »
This gene plays a role in DNA metabolism and repair. »
Human MPG wild-type allele is located in the vicinity of 16p13.3 and is approximately 9 kb in length. This allele, which encodes… »
This gene plays a regulatory role in megakaryocytopoiesis and platelet formation. »
Human MPL wild-type allele is located in the vicinity of 1p34.2 and is approximately 46 kb in length. This allele, which encodes… »
A type of soft tissue sarcoma that develops in cells that form a protective sheath (covering) around peripheral nerves, which are nerves… »
This gene is involved in the modulation of neutrophil microbicidal activity. »
Human MPO wild-type allele is located in the vicinity of 17q23.1 and is approximately 11 kb in length. This allele, which encodes… »
This gene plays a role in cell proliferation, cytoskeletal modeling and intercellular communication. »
Human MPP1 wild-type allele is located within Xq28 and is approximately 27 kb in length. This allele, which encodes 55 kDa erythrocyte… »
This gene is involved in cytoskeletal modeling, cell proliferation and intercellular communication. »
Human MPP2 wild-type allele is located within 17q12-q21 and is approximately 32 kb in length. This allele, which encodes MAGUK p55 subfamily… »
This gene plays a role in cytoskeletal modeling, intercellular communication and cell proliferation. »
Human MPP3 wild-type allele is located within 17q12-q21 and is approximately 32 kb in length. This allele, which encodes MAGUK p55 subfamily… »
A regimen consisting of melphalan, prednisone and thalidomide used as induction therapy for multiple myeloma. »
This gene plays a role in cell migration. »
Human MPZL1 wild-type allele is located in the vicinity of 1q24.2 and is approximately 69 kb in length. This allele, which encodes… »
A measure of how fast cancer cells are dividing and growing. To find the MR, the number of cells dividing in a… »
An instrument that integrates magnetic resonance imaging with delivery of radiation therapy. »
This gene plays a role in antigen presentation. »
Human MR1 wild-type allele is located in the vicinity of 1q25.3 and is approximately 29 kb in length. This allele, which encodes… »
A procedure that uses radio waves and a powerful magnet linked to a computer to create detailed pictures of the blood vessels… »
This gene is involved in development and plays a role in signal transduction. »
Human MRAS wild-type allele is located in the vicinity of 3q22.3 and is approximately 58 kb in length. This allele, which encodes… »
This gene is involved in endocytosis of glycoproteins by macrophages. »
Human MRC1 wild-type allele is located in the vicinity of 10p12.33 and is approximately 102 kb in length. This allele, which encodes… »
This gene is involved in extracellular matrix remodeling. »
Human MRC2 wild-type allele is located in the vicinity of 17q23.2 and is approximately 66 kb in length. This allele, which encodes… »
The MRE11/RAD50 double-strand break repair complex consists of 5 proteins: Nibrin, p200, p400, MRE11, and RAD50. This complex possesses manganese-dependent single-stranded DNA… »
This gene plays a role in DNA recombination and repair. »
Human MRE11A wild-type allele is located in the vicinity of 11q21 and is approximately 77 kb in length. This allele, which encodes… »
A procedure in which radio waves and a powerful magnet linked to a computer are used to create detailed pictures of areas… »
The numeric value to indicate an increase in voxel signal over time for an MRI, expressed as signal intensity units per… »
Magnetic resonance imaging (MRI) uses a large magnet and radio waves to look at organs and structures inside your body. Health care… »
A type of RNA found in cells. mRNA molecules carry the genetic information needed to make proteins. They carry the information… »
Transport of messenger RNA from its nuclear site of transcription to the cytoplasm, where the message is translated into protein by… »
The synthesis or transcription of messenger RNA. »
mRNA Surveillance works within elaborate cellular mechanisms to ensure accurate gene expression by assessing suitable mRNA quality for translation and prevents the… »
An RNA transport gene that encodes a protein specifically involved in the transport of mRNA. »
A non-small cell lung cancer (NSCLC) vaccine containing six modified mRNAs, which encode six different NSCLC associated antigens, with potential antitumor and… »
A prostate cancer vaccine containing mRNAs encoding prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), prostate stem cell antigen (PSCA) and… »
A prostate cancer vaccine containing six messenger RNAs (mRNAs) encoding for antigens upregulated in prostate cancer, including mRNAs for prostate specific antigen… »
This gene is involved in mitochondrial RNA translation. »
Human MRPL45 wild-type allele is located in the vicinity of 17q21.2 and is approximately 26 kb in length. This allele, which encodes… »
A courtesy title prefixed to the name of a married woman. »
Modified Rankin Scale (MRS) Modified Rankin Scale Score. »
A question associated with the MRS questionnaire. »
MRSA stands for methicillin-resistant Staphylococcus aureus. It causes a staph infection (pronounced "staff infection") that is resistant to several common… »
A noninvasive imaging method that provides information about cellular activity (metabolic information). It is used along with magnetic resonance imaging (MRI) which… »
This gene plays a role in signal transduction. »
Human MRVI1 wild type allele, which is located in the vicinity of 11p15 and is approximately 118 kb in length. This allele,… »
A courtesy title used before the name of a woman without making a distinction between married and unmarried status. »
A substance that is being studied for its ability to make cancer cells respond better to chemotherapy drugs to which they have… »
Sustancia en estudio por su capacidad para hacer que las células cancerosas respondan mejor a los medicamentos quimioterapéuticos a los que se… »
A synthetic compound that binds to the DNA minor groove and cause anti tumor activity. »
A substance that is being studied in the treatment of cancers of the blood. It belongs to the family of drugs called… »
Sustancia en estudio para el tratamiento de los cánceres de la sangre. Es un tipo de inhibidor de la deacetilasa de… »
This gene plays a regulatory role in cellular differentiation. »
Human MS4A1 wild-type allele is located within 11q12 and is approximately 13 kb in length. This allele, which encodes B-lymphocyte antigen CD20… »
This gene is involved in immunoglobulin binding. »
Human MS4A2 wild-type allele is located within 11q12-q13 and is approximately 10 kb in length. This allele, which encodes high affinity immunoglobulin… »
This gene is involved in the repression of transcription. It may also play a role in the regulation of B-cell differentiation. … »
Human MSC wild-type allele is located in the vicinity of 8q21 and is approximately 3 kb in length. This allele, which encodes… »
CD34+ peripheral blood stem cells (PBSC) isolated from patient with hematopoietic cell tumor, and transfected with murine stem cell virus retroviral vector… »
The RNA portion of the msDNA molecule, which contains two stem-loop structures and varies widely in length across bacterial species. »
This gene plays a role in DNA mismatch repair mutations in the gene result in hereditary nonpolyposis colorectal cancer-1. »
Human MSH2 wild-type allele is located within 2p22-p21 and is approximately 80 kb in length. This allele, which encodes DNA mismatch repair… »
This gene plays a role in DNA mismatch repair and has been implicated in several cancers. »
Human MSH3 wild-type allele is located within 5q11-q12 and is approximately 222 kb in length. This allele, which encodes DNA mismatch repair… »
This gene is involved in DNA repair and meiotic recombination. »
Human MSH4 wild-type allele is located within 1p31 and is approximately 116 kb in length. This allele, which encodes MutS protein homolog… »
This gene is involved in mismatch repair and plays a role in several cancers. »
Human MSH6 wild-type allele is located within 2p16 and is approximately 24 kb in length. This allele, which encodes DNA mismatch repair… »
A change that occurs in the DNA of certain cells (such as tumor cells) in which the number of repeats of microsatellites… »
This gene is involved in the modulation of translation. »
Human MSI1 wild-type allele is located within 12q24.1-q24.31 and is approximately 28 kb in length. This allele, which encodes RNA-binding protein Musashi… »
This gene is involved in translational regulation. »
Human MSI2 wild-type allele is located in the vicinity of 17q22 and is approximately 423 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(7;17)(p15;q23) which fuses exon 9 of the MSI2 gene with exon 1b of… »
A fusion protein encoded by the MSI2/HOXA9 fusion gene. This protein is comprised of the 2 RNA recognition motifs in the RNA-binding… »
Important in eukaryotic gene regulation, histone acetylation and deacetylation are catalyzed by histone deacetylase complexes that include SAP30, SAP18, histone deacetylases, histone-binding… »
This gene may be involved in cellular adhesion. »
Human MSLN wild-type allele is located in the vicinity of 16p13.3 and is approximately 8 kb in length. This allele, which encodes… »
A combination preparation of glucosamine, a hexosamine sugar polymer, and methyl sulfonyl methane (MSM), a derivative of dimethyl sulphoxide, with anti-arthritic and… »
This gene may play a role in the modulation of autocrine paracrine factor in reproductive tissues, however a specific function has not… »
Human MSMB wild-type allele is located in the vicinity of 10q11.2 and is approximately 13 kb in length. This allele, which encodes… »
This gene plays a role in both cell adhesion and cytoskeleton modeling. »
Human MSN wild-type allele is located in the vicinity of Xq11.1 and is approximately 74 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(X;2)(q11;p23) which fuses most of the coding sequence of the MSN gene with… »
A fusion protein encoded by the MSN/ALK fusion gene. This protein is comprised of most of the moesin protein, including the band… »
This gene plays a role in the transport of both lipoproteins and cholesterol. »
Human MSR1 wild-type allele is located in the vicinity of 8p22 and is approximately 450 kb in length. This allele, which encodes… »
Medicamento que actúa como un estrógeno sobre algunos tejidos, pero bloquea el efecto del estrógeno sobre otros tejidos. El tamoxifeno y el… »
This gene encodes a non-functional member of the peptidase S1 family. »
Human MST1L wild-type allele is located 1p36.13 and is approximately 15 kb in length. This allele encodes putative macrophage-stimulating protein MSTP9, a… »
This gene plays a diverse regulatory role in several processes such as: proliferation, migration, host defense and fertilization. »
Human MST1R wild-type allele is located in the vicinity of 3p21.3 and is approximately 17 kb in length. This allele, which encodes… »
This gene plays a role in cell differentiation and the regulation of transcription. It is also involved in the regulation of muscle… »
Human GDF8 wild-type allele is located in the vicinity of 2q32.2 and is approximately 7 kb in length. This allele, which encodes… »
This gene is involved in transcriptional repression and embryogenesis. »
Human MSX1 wild-type allele is located within 4p16.3-16.1 and is approximately 4 kb in length. This allele, which encodes homeobox protein MSX-1,… »
Técnica mental usada para promover la relajación, reducir la tensión y mejorar la calidad de vida. MT es la marca registrada de… »
This gene is involved in chelation. »
Human MT1G wild-type allele is located in the vicinity of 16q13 and is approximately 1 kb in length. This allele, which encodes… »
This gene is involved in cellular growth regulation and is expressed exclusively in the nervous system. »
Human MT3 wild-type allele is located within 16q13 and is approximately 2 kb in length. This allele, which encodes metallothionein-3 protein, is… »
A cement like material used for apical seals and as a reparative material for perforation of the tooth root. »
This gene plays a role in transcriptional regulation. »
Human MTA1 wild-type allele is located in the vicinity of 14q32.3 and is approximately 50 kb in length. This allele, which encodes… »
This gene plays a role in chromatin modification. »
Human MTA2 wild-type allele is located within 11q12-q13.1 and is approximately 9 kb in length. This allele, which encodes metastasis-associated protein MTA2,… »
Approximately 30% of breast carcinomas lack ER expression. Presumably, these breast cancers become estrogen independent through genetic alterations that bypass the requirement… »
This gene plays a role in purine salvage. »
Human MTAP wild-type allele is located in the vicinity of 9p21 and is approximately 230 kb in length. This allele, which encodes… »
Sistema médico en uso durante miles de años para prevenir, diagnosticar y tratar enfermedades. Se basa en la creencia que… »
This gene is involved in transport through the inner mitochondrial membrane. »
Human MTCH2 wild-type allele is located in the vicinity of 11p11.2 and is approximately 25 kb in length. This allele, which encodes… »
This gene plays a role in the proliferation of T cells and is involved in cell cycle regulation. »
Human MTCP1 wild-type allele is located in the vicinity of Xq28 and is approximately 86 kb. This allele, which encodes protein p13… »
This gene may be involved in the regulation of cellular proliferation. »
Human MTCP1NB wild-type allele is located in the vicinity of Xq28 and is approximately 10 kb. This allele, which encodes protein p8… »
The highest dose of a drug or treatment that does not cause unacceptable side effects. The MTD is determined in clinical trials… »
This gene is involved in the regulation of transcription. »
Human MTDH wild-type allele is located in the vicinity of 8q22.1 and is approximately 86 kb in length. This allele, which encodes… »
The hydrochloride salt of a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF-1 inhibitor LOR-253… »
This gene plays a role in folate metabolism. »
Human MTHFD1 wild-type allele is located in the vicinity of 14q24 and is approximately 72 kb in length. This allele, which encodes… »
This gene is involved in the regulation of folate metabolism. »
Human MTHFD1L wild-type allele is located in the vicinity of 6q25.1 and is approximately 236 kb in length. This allele, which encodes… »
This gene is involved in the metabolism of folic acid. »
Human MTHFD2 wild-type allele is located in the vicinity of 2p13.1 and is approximately 19 kb in length. This allele, which encodes… »
This gene is involved in folate metabolism and methionine biosynthesis. »
Human MTHFR wild-type allele is located in the vicinity of 1p36.3 and is approximately 19 kb in length. This allele, which encodes… »
This gene plays a role in ligand-dependent signal transduction. »
Human MTNR1B wild-type allele is located within 11q21-q22 and is approximately 13 kb in length. This allele, which encodes melatonin receptor type… »
A protein that helps control several cell functions, including cell division and survival, and binds to rapamycin and other drugs. mTOR may… »
Proteína que ayuda a controlar varias funciones celulares, incluso la multiplicación y la supervivencia de las células; se une con la rapamicina… »
This gene plays a role in apoptosis, cell growth, differentiation and proliferation. »
A substance that blocks a protein called mTOR, which helps control cell division. Blocking mTOR’s action may keep cancer cells from growing… »
An orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD2014 inhibits the activity… »
An inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity… »
An orally available inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor CC-223 inhibits the activity… »
An orally bioavailable mammalian target of rapamycin (mTOR) kinase inhibitor with potential antineoplastic activity. mTOR kinase inhibitor OSI-027 binds to and inhibits… »
mTOR (mammalian target of rapamycin) appears to play a central role in signaling caused by nutrients and mitogens such as growth factors… »
Human MTOR wild-type allele is located in the vicinity of 1p36.2 and is approximately 156 kb in length. This allele, which encodes… »
An active metabolite of NV-128, a novel flavonoid small molecule inhibitor of the mammalian Target of Rapamycin (mTOR), with potential antineoplastic… »
A protein complex that is involved in the both serine/threonine phosphorylation and the regulation of protein synthesis in response to cellular… »
A protein complex that is involved in both serine/threonine phosphorylation and cytoskeleton remodeling in response to cellular stress. »
This gene plays a role in methionine biosynthesis. »
Human MTR wild-type allele is located in the vicinity of 1q43 and is approximately 109 kb in length. This allele, which encodes… »
This gene plays a role in the metabolism of vitamins and amino acids. »
Human MTRR wild-type allele is located in the vicinity of 5p15.31 and is approximately 55 kb in length. This allele, which encodes… »
A drug used to treat some types of cancer, rheumatoid arthritis, and severe skin conditions, such as psoriasis. MTX stops cells from… »
Medicamento que se usa para tratar ciertos tipos de cáncer, la artritis reumatoide y afecciones graves de la piel, como la… »
The determination of the amount of mu glutathione-s-transferase present in a sample. »
The determination of the ratio of mu glutathione-s-transferase compared to creatinine present in a sample. The measurement may be expressed as a… »
A clonal disorder characterized by the secretion of a mu heavy chain that lacks a variable region. Most patients present with… »
A protein found on certain epithelial cells, which line the inside and outside surfaces of the body. It may be found in… »
Proteína que se encuentra en ciertas células epiteliales que revisten el interior y el exterior de las superficies del cuerpo. Se puede… »
MUC-1 antigen is a mammary-type apomucin, a high molecular weight transmembrane glycoprotein, of which the extracellular domain is formed by a repeating… »
A cancer vaccine comprised of a synthetic peptide derived from the mucin 1 (MUC1) antigen with potential antineoplastic activity. Upon administration, MUC1… »
A peptide vaccine containing human mucin 2 (MUC2) protein conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. MUC2, a secretory… »
This gene plays a role in cellular signal transduction and is used as a biomarker for breast cancer. »
A vaccine preparation containing mucus 1 (MUC1) peptide and the adjuvant poly-ICLC with potential immunostimulatory and antineoplastic activities. Upon administration, MUC1 peptide-poly-ICLC… »
Human MUC1 wild-type allele is located within 1q21 and is approximately 121 kb in length. This allele, which encodes mucin-1 protein, plays… »
A peptide vaccine, containing human tumor-associated epithelial mucin (MUC1) conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with MUC1-KLH… »
A peptide vaccine containing the human tumor-associated antigen epithelial mucin (MUC1 antigen) conjugated with keyhole limpet hemocyanin (KLH) and combined with the… »
An optimized small peptide drug candidate targeting epithelial mucin (MUC1) with antineoplastic activity. MUC1-targeted peptide GO-203-2C interacts with oncoprotein MUC1 C-terminal subunit… »
This gene is involved in both cellular adhesion and the maintenance of mucosal surfaces. »
Human MUC16 wild-type allele is located in the vicinity of 19q13.2 and is approximately 132 kb in length. This allele, which encodes… »
An antibody drug conjugate (ADC) consisting of a humanized IgG1 monoclonal antibody targeting the MUC16 protein (CA-125) conjugated to, via a cleavable… »
This gene plays a role in the protection of the respiratory and gastrointestinal tracts. »
Human MUC5AC wild-type allele is located in the vicinity of 11p15.5 and is approximately 146 kb in length. This allele, which encodes… »
A response indicating that an individual feels much less limited than others. »
A response indicating that an individual has been much less socially active than before. »
A response indicating that an individual feels much more limited than others. »
A response indicating that an individual has been much more socially active than before. »
A thick, viscous plant cell product; the term is usually applied to plant gums. (DRI) »
An albuminoid substance containing mucopolysaccharides and protein which is contained in mucus, and gives to the latter secretion its peculiar ropy… »
A morphologic and histochemical finding indicating depletion of mucin in the glands. »
Mucin is expressed by most glandular epithelia. Tandem repeats characterize the core mucin protein, apomucin; variation of the protein derives from… »
Mucin-1 (1255 aa, ~122 kDa) is encoded by the human MUC1 gene. This protein plays a role in both signaling and cell… »
An immunohistochemical technique used to detect the gene product of the MUC1 gene, using monoclonal antibodies directed against mucin-1 glycoprotein. »
Mucin-16 (22152 aa, ~2353 kDa) is encoded by the human MUC16 gene. This protein may be involved in both cellular adhesion and… »
An immunohistochemical technique used to detect the gene product of the MUC2 gene, using monoclonal antibodies directed against mucin-2 glycoprotein. »
Mucin-5AC (5030 aa, ~527 kDa) is encoded by the human MUC5AC gene. This protein plays a role in the defense of the… »
Precancerous dysplastic lesions depleted of mucin in the colonic mucosa of the mouse. »
Encoded by human Small Breast Epithelial Mucin Gene, 90-amino acid 9 kD Small Breast Epithelial Mucin is a putative low molecular weight… »
An invasive adenocarcinoma composed of malignant glandular cells which produce mucin. »
An intrahepatic cholangiocarcinoma that produces abundant mucin. »
A protein/sugar compound made by some cancer cells. »
Compuesto de proteína y azúcar que producen algunas células cancerosas. »
Que contiene o se parece a la mucina, el componente principal del moco. »
Containing or resembling mucin, the main compound in mucus. »
An invasive adenocarcinoma composed of malignant glandular cells which contain intracytoplasmic mucin. Often, the infiltrating glandular structures are associated with mucoid stromal… »
A mucinous adenocarcinoma characterized by the presence of malignant glandular cells which resemble the endocervical epithelium. »
A benign adenofibroma characterized by the presence of epithelial cells which contain intracytoplasmic mucin and a fibrotic stroma. A representative example is… »
An invasive adenocarcinoma of the breast characterized by the presence of islands of small and uniform cells, surrounded by large amounts of… »
A columnar epithelial cell found in the bronchi. It secretes mucus. »
A well differentiated morphologic variant of bronchiolo-alveolar lung carcinoma characterized by tall columnar cells and mucin production. »
A type of cancer that begins in cells that line certain internal organs and produce mucin (the main component of mucus). … »
An invasive adenocarcinoma characterized by cystic changes and the presence of malignant glandular cells which contain intracytoplasmic mucin. It may arise from… »
A benign neoplasm characterized by the presence of cystic structures lined by mucinous columnar epithelial cells in a fibrotic stroma. »
A benign or low malignant potential cystic epithelial neoplasm composed of cells which contain intracytoplasmic mucin. It may arise from the ovary,… »
A variant of gastric adenocarcinoma with more than half of the tumor containing extracellular mucinous pools. »
A low grade carcinoma of the kidney characterized by the presence of tubules which are separated by mucinous stroma. Often the tubular… »
This gene plays a role in cancer cell metastasis. »
Human MUCL1 wild-type allele is located in the vicinity of 12q and is approximately 4 kb in length. This allele, which encodes… »
A viscous, oral hydrogel rinse intended for the management of oral mucositis/stomatitis. Mucoadhesive oral wound rinse consists of purified water, glycerin, benzyl… »
An orally available, mucoadhesive lipid preparation consisting of paclitaxel, a compound extracted from the Pacific yew tree Taxus brevifolia, in a formulation… »
A fungal infection of the skin, nails, oral and vaginal mucosal sites caused by species of the genus Candida. It manifests with… »
A carcinoma of the breast characterized by pools of mucin and islands of malignant squamous cells. Mucoepidermoid carcinomas of the breast… »
A carcinoma morphologically characterized the presence of cuboidal mucous cells, goblet-like mucous cells, squamoid cells, cystic changes, and a fibrotic stromal… »
The interface between the more apically located alveolar mucosa and the more coronally located gingiva. »
A group of inherited lysosomal storage diseases characterized by accumulation of lipids and carbohydrates in the tissues, resulting in mental disabilities and… »
An autosomal recessive lysosomal storage disease caused by mutations in the MCOLN1 gene. It is characterized by psychomotor developmental delays and ophthalmologic… »
A flap of mucosal, and possibly gingival, tissue including the periosteum, reflected from bone and created in the process of conducting orthodontic… »
A group of autosomal recessive or X-linked inherited lysosomal storage disorders affecting the metabolism of mucopolysaccharides, resulting in the accumulation of mucopolysaccharides… »
The most common type of mucopolysaccharidosis. It is inherited in an autosomal recessive pattern. It comprises a group of lysosomal storage diseases… »
A rare autosomal recessive lysosomal storage disease caused by deficiency of the enzyme heparan sulfate sulfatase. It is characterized by behavioral changes,… »
A rare autosomal recessive lysosomal storage disease caused by deficiency of the enzyme N-acetyl-alpha-D-glucosaminidase. It is characterized by behavioral changes, sleep disturbances,… »
A rare autosomal recessive lysosomal storage disease caused by deficiency of the enzyme acetyl-CoA:alpha-glucosaminide acetyltransferase. It is characterized by behavioral changes, sleep… »
A rare autosomal recessive lysosomal storage disease caused by deficiency of the enzyme N-acetylglucosamine-6-sulfatase. It is characterized by behavioral changes, sleep disturbances… »
A rare autosomal recessive lysosomal storage disease caused by deficiency of the enzyme galactosamine-6-sulfatase. It is characterized by skeletal and central nervous… »
A rare autosomal recessive lysosomal storage disease caused by deficiency of the enzyme beta galactosidase. It is characterized by skeletal dysplasia and… »
The moist, inner lining of some organs and body cavities (such as the nose, mouth, lungs, and stomach). Glands in the mucosa… »
Revestimiento interior húmedo de algunos órganos y cavidades del cuerpo (como la nariz, la boca, los pulmones y el estómago). Las glándulas… »
Revestimiento interno de las mejillas. »
Recubrimiento interno de los labios. »
The lining of the fleshy folds surrounding the mouth. It is comprised of the epithelium, basement membrane, lamina propria mucosae, and lamina… »
The lining of the inferior fleshy fold bordering the mouth. It is comprised of the epithelium, basement membrane, lamina propria mucosae, and… »
The lining of the superior fleshy fold bordering the mouth. It is comprised of the epithelium, basement membrane, lamina propria mucosae, and… »
Lymphoid tissue located beneath the mucosal epithelia of those mucosal surfaces that have contact with the external environment, such as the respiratory,… »
A type of cancer that arises in cells in mucosal tissue that are involved in antibody production. Also called MALT lymphoma. … »
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (824 aa, ~92kDa) is encoded by the MALT1 gene. This protein may play a role… »
Decrease in parenchymal cell number and/or size, often associated with shortening of villi (SI) and/or glands (LI) »
Maintaining the integrity of the gastrointestinal tract despite the continual presence of microbial flora and injurious agents is essential. Epithelial repair requires… »
Extension of the normal mucosa into and through the muscular wall and maintaining differentiation of the mucosal cell types. »
Focal or diffuse epithelial hyperplasia in the intestinal mucosa of the mouse. »
Immunoglobulin A secretion by mucosal epithelia in the gastrointestinal, respiratory, and genitourinary tracts. Mucosal immunity promotes resistance toward bacteria, viruses, and parasites… »
An acute or chronic infectious process affecting a mucosal surface. »
An acral lentiginous melanoma affecting mucosal surfaces. »
A clinical finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM… »
A clinical finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM… »
A pathologic finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM… »
A pathologic finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM… »
A pathologic finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM… »
A pathologic finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM… »
A finding about one or more characteristics of mucosal melanoma of the head and neck, following the rules of the TNM AJCC… »
Administration of a substance to the mucosa; often resulting in systemic action due to absorption. »
A spray intended for administration to the mucosa. »
A complication of some cancer therapies in which the lining of the digestive system becomes inflamed. Often seen as sores in the… »
Complicación producida por algunas terapias contra el cáncer en la que el revestimiento del aparato digestivo se inflama. Se observa a menudo… »
A gelatinous type of connective tissue that is found in the umbilical cord. »
A mucous containing cyst arising from the minor salivary glands in the oral cavity. »
The moist, inner lining of some organs and body cavities (such as the nose, mouth, lungs, and stomach). Glands in the mucous… »
A hemangioma arising from the mucous membranes. »
A solution intended for administration to the surface of the mucosa membranes. »
A polypoid lesion that arises from the cervix and contains mucus. »
Salivary glands that produce and secrete a saliva made up exclusively of mucous. »
The determination of the number of mucous threads present in a sample. »
A thick, slippery fluid made by the membranes that line certain organs of the body, including the nose, mouth, throat, and… »
A disorder of the intestines commonly marked by abdominal pain, bloating, and changes in a person’s bowel habits. This may include… »
A question about an individual's mucus in mouth or throat at its worst. »
It is the epithelium cell that produces mucin gel adherent to the mucosal surface. Mucus-secreting cells are widely distributed through the… »
Última muela que aparece en la parte posterior de la mandíbula superior e inferior. Estas muelas aparecen entre los 17 y 23… »
Muellerian-inhibiting factor (560 aa, ~59 kDa) is encoded by the human AMH gene. This protein plays a role in the development of… »
A rare autosomal dominant inherited disorder caused by mutations in the FGFR3 gene. It is characterized by premature fusion of cranial bones,… »
Planta semiparasitaria que crece en algunos tipos de árboles. Los extractos de muérdago están en estudio para el tratamiento de cáncer. … »
Tipo de muerte celular en la que una serie de procesos moleculares en la célula conducen a su muerte. Este es … »
Muerte fácil o sin dolor, o la terminación intencional de la vida de una persona que padece una enfermedad incurable o dolorosa,… »
Muerte que se produce antes de la edad promedio de muerte en una población determinada. En los Estados Unidos, la edad promedio… »
Trastorno que se caracteriza por la muerte instantánea e inesperada de un niño sano menor de 1 año. Habitualmente, cuando duerme. Se… »
Muestra de materiales como orina, sangre, tejido, células, ADN, ARN y proteínas de seres humanos, animales o plantas. Las muestras biológicas se… »
Tejido que se toma del cuerpo y se observa bajo un microscopio para determinar si hay una enfermedad. »
Procedimiento en el que se toma una muestra de sangre de cierta vena y se verifica si tiene sustancias específicas liberadas por… »
A usually autosomal dominant inherited neoplastic syndrome caused by mutations in the hMSH-2 and hMLH-1 genes. It is characterized by the presence… »
A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to… »
Tipo de anticuerpo monoclonal usado para detectar o tratar el cáncer. Los anticuerpos monoclonales son sustancias que se producen en el laboratorio;… »
An autosomal recessive inherited disorder caused by mutations in the TRIM37 gene. It is characterized by marked growth retardation and abnormalities in… »
Two ducts of the embryo which empty into the cloaca, and which in the female develop into vagina, uterus and oviducts; in… »
A deficiency of the Mullerian inhibiting substance, which is secreted by the Sertoli cells during embryogenesis. It can result in unilateral or… »
A rare cancer of the uterus, ovary, or fallopian tubes. »
A vial intended to contain more than one dose of the drug product. »
An orally available, small molecule inhibitor of AGC group kinases, with potential antineoplastic activity. AT13148 inhibits, in an ATP-competitive manner, the enzymatic… »
A method for simultaneous detection of multiple target molecules. It utilizes specific antibodies for the analytes of interest coupled to fluorescent polystyrol… »
A static light scattering technique involving measurement of the amount of light scattered by a suspension at multiple angles relative to the… »
Cancer cells resistant to a diverse set of hydrophobic drugs are known as MDR cells (multidrug-resistant). Large membrane proteins overproduced in MDR… »
A microorganism, often a bacterium, that is not susceptible to standard antimicrobial therapies. »
A peptide vaccine containing five immunogenic peptide epitopes of the human folate receptor alpha (FR alpha or FOLR1), including FR30, FR56, FR76,… »
A peptide cancer vaccine consisting of a combination of peptides derived form several melanoma epitopes. Vaccination with multi-epitope melanoma peptide vaccine stimulates… »
A common form of dementia caused by multiple cortical or subcortical cerebral infarctions. »
Specifies whether a study is designed to be conducted at more than one site concurrently. »
A clinical trial that is carried out at more than one medical institution. »
A vaccine consisting of an inactivated, Modified Vaccinia Ankara (MVA) viral vector encoding three herpes virus cytomegalovirus (CMV) tumor-associated antigens (TAAs), including… »
Creating slice views from a 3D image with their planes having desired orientations. »
A type of spiral computed tomography that employs multiple rows of detectors, each capable of producing a simultaneous image (slice). »
A preparation containing a mixture of multiple naturally occurring, active subtypes 1, 2, 8, 10, 14 and 21 of interferon alpha (IFN-alpha)… »
A nanotube consisting of single-walled nanotubes layered inside each other. »
A biologic function or process involving coordinated groups or populations of single cell types, mixed cell types, or tissues. »
A multi-center study of HIV disease progression and heterosexual transmission begun in 1982. »
A clinical trial that is carried out at more than one medical institution. »
Having many centers. A multicentric cancer consists of a primary tumor with satellites of cancerous growth in surrounding tissues. »
A form of angiofollicular lymphoid hyperplasia characterized by fever, generalized lymphadenopathy, hypergammaglobulinemia, and dysfunction of multiple organs. Other signs and symptoms… »
Breast cancer in which there is more than one tumor, all of which have formed separately from one another. The tumors are… »
A breast carcinoma characterized by the presence of multiple cancerous tumors that originate from different clones and are usually located in different… »
A term that usually refers to cancer growth and is defined by the presence of multiple lesions, each originating from a different… »
A systemic disease, often associated with arthritis, fever, and weight loss. The cutaneous lesions consist of histiocytes, which are usually confined… »
A papillary carcinoma arising from the thyroid gland from multiple foci. »
A DNA/RNA chimera comprised of a single-stranded DNA molecule covalently bound to an internal guanosine of a RNA molecule. »
An intermediate grade neoplasm arising from mesothelial cells. It occurs in the peritoneum, extraperitoneal space, omentum, or pelvic or abdominal viscera. It… »
Having or involving or marked by several dimensions or aspects, generally indicating dimensionalities beyond 3D. »
A well-validated, self-report inventory for the assessment of body image. »
A 20-item self-report instrument designed to measure fatigue. It covers the following dimensions: General Fatigue, Physical Fatigue, Mental Fatigue, Reduced Motivation and… »
Various NMR methods that can be used to determine 3D structures of macromolecules. »
En medicina, este término se utiliza para describir el enfoque de la planificación del tratamiento que incluye una cantidad de médicos y… »
In medicine, a term used to describe a treatment planning approach or team that includes a number of doctors and other health… »
A treatment planning approach in which a number of doctors who are experts in different specialties (disciplines) review and discuss the medical… »
Free-standing or institution-based clinics devoted to pain management from a multidisciplinary perspective. Team members usually include physicians, nurses, social workers, physical… »
Adaptation of tumor cells to anticancer drugs in ways that make the drugs less effective. »
Mammalian P-glycoproteins are encoded by the MDR gene family and belong to the ATP-binding cassette vectorial transport protein class; the CFTR chloride… »
Multidrug Resistance Induction involves initiation of activities of biologic molecules or complexes involved in processes that increase the ability of cancer cells… »
Treatment used to make cancer cells less resistant to anticancer drugs. »
A drug that makes tumor cells more sensitive to the effects of chemotherapy. »
Simultaneous resistance to a spectrum of unrelated drugs following exposure to a single agent. Mechanisms involve expression of multidrug efflux pumps (p-glycoprotein),… »
Multidrug resistance-associated protein 4 (1325 aa, ~150 kDa) is encoded by the human ABCC4 gene. This protein plays a role in platelet… »
Multidrug resistance-associated protein 5 (1437 aa, ~161 kDa) is encoded by the human ABCC5 gene. This protein plays a role in the… »
Arising from, pertaining to, or having many locations. »
An electrocardiographic finding of premature atrial complexes which have 2 or more distinct morphologies, suggesting origin at more than one atrial… »
An electrocardiographic finding of a supraventricular arrhythmia characterized by 3 or more distinct P wave morphologies with an isoelectric baseline, variable PR… »
Breast cancer in which there is more than one tumor, all of which have arisen from one original tumor. The tumors are… »
A breast carcinoma characterized by the presence of multiple cancerous tumors that originate from the same clone and are usually located in… »
The occurrence of multiple and independent glioblastomas that are unrelated to inherited neoplastic syndromes. »
A lesion arising from or having many locations. »
A clinico-pathological entity reflecting the multiple polyps throughout the gastrointestinal tract created as a result of involvement by a non-Hodgkin lymphoma. … »
A primary bone osteosarcoma affecting multiple bone sites. »
An electrocardiographic finding of premature ventricular complexes which have two or more distinct morphologies, suggesting origin at more than one ventricular… »
The innermost layer of the cerebral cortex. It consists of numerous small neurons, small pyramidal cells, stellate cells, especially superficially and fusiform… »
An orally available, multivalent herbal formulation containing a novel mixture of whole extracts from three commonly used Chinese medicinal herbs Ganoderma lucidum… »
A laboratory test in which many genes are studied in a sample of tissue. Multigene tests may help find mutations (changes) in… »
A drug used in MRI to help make clear pictures of blood vessels in the brain, spine, and nearby tissues. It is… »
Medicamento que se usa en las IRM para ayudar a obtener imágenes claras de los vasos sanguíneos del cerebro, la columna vertebral… »
A multikinase inhibitor with potential antineoplastic activity. Multikinase inhibitor 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular… »
An orally bioavailable small-molecule inhibitor of p38 and Tie2 kinases with potential antineoplastic, anti-inflammatory and antiangiogenic activities. p38/Tie2 kinase inhibitor Arry-614 binds… »
A small synthetic molecule and aurora kinase (AK) inhibitor with potential antineoplastic activity. AT9283 selectively binds to and inhibits AKs A and… »
A multikinase inhibitor with potential antineoplastic activity. Upon intravenous infusion, multikinase inhibitor SAR103168 may, through the inhibition of multiple kinases, inhibit the… »
A tablet composed of active and/or inert ingredient(s) that have been compressed into multiple layers and is designed to release active and/or… »
A tablet composed of active and/or inert ingredient(s) that have been compressed to form a tablet that contains multiple layers. »
A rare type of renal cell carcinoma. It is a well-circumscribed multicystic mass without solid areas. The inner lining of… »
A multicystic lesion that arises from the epithelial component of the thymus gland. It is usually associated with the presence of… »
A computer-controlled presentation of some combination of audio, video, animation, graphics, still photo, and/or text where users can control the presentation and… »
Simultaneous use of more than one imaging technique. »
Therapy that combines more than one method of treatment. Also called combination therapy and multimodality treatment. »
Therapy that combines more than one method of treatment. Also called combination therapy and multimodality therapy. »
A self-administered questionnaire designed to assess a patient's level of nausea and vomiting associated with chemotherapy. »
A discreet probability distribution, which is a generalization of the binomial distribution. This distribution models systems in which each trial results in… »
The fitting of data to multivariable deterministic or statistical models; extraction of the number of independent parameters that contribute to the observable… »
Having, relating to, or consisting of more than one individual, element, part, or other component; manifold. »
A rare autosomal recessive inherited metabolic disorder caused by mutations in the ETFA, ETFB, and ETFDH genes. It is characterized by defects… »
A condition in which multiple adenomas develop in the gastrointestinal tract. »
Present at many sites of the body. »
Multiple fetuses birthed live or dead in a single pregnancy regardless of gestational age, and regardless of whether the fetuses were birthed… »
More than one cancer site. »
A procedure used for correction of p-value due to multiple testing. »
A rare, inherited disorder that affects the endocrine glands and can cause tumors in the parathyroid and pituitary glands and the… »
A rare, genetic disorder that affects the endocrine glands and can cause tumors in the thyroid gland, parathyroid glands, and adrenal… »
A rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and… »
A rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and… »
An autosomal dominant inherited neoplastic syndrome characterized by the development of various endocrine neoplasms and abnormalities in various anatomic sites. There are… »
An inherited condition that may result in the development of cancers of the endocrine system. There are several types of multiple endocrine… »
Multiple endocrine neoplasia caused by inactivation of the tumor suppressor gene MEN-1. Patients may develop hyperparathyroidism and parathyroid gland adenomas, pituitary gland… »
A rare, inherited disorder that affects the endocrine glands and can cause tumors in the parathyroid and pituitary glands and the… »
A rare, genetic disorder that affects the endocrine glands and can cause tumors in the thyroid gland, parathyroid glands, and adrenal… »
Multiple endocrine neoplasia caused by mutation of the RET gene. Patients develop medullary thyroid carcinomas, and may also develop pheochromocytomas and parathyroid… »
A rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and… »
Multiple endocrine neoplasia caused by mutation of the RET gene. Patients develop medullary thyroid carcinomas and numerous neural defects including neuromas. … »
A rare, genetic disorder that affects the endocrine glands and causes a type of thyroid cancer called medullary thyroid cancer, pheochromocytoma, and… »
A pregnancy involving twins or higher-order multiple fetuses (e.g., triplets, quadruplets). »
An inherited disorder marked by the formation of many noncancerous growths called hamartomas. These growths occur in the skin, breast, thyroid, colon,… »
A person living in the United States of Mexican, Puerto Rican, Cuban, Central or South American, or other Spanish culture or… »
The substitution of missing data with the average derived from multiple datasets of data that is not missing. »
Multiple meningiomas that arises from the spinal meninges. »
A lobular hemangioma present in multiple anatomical sites. »
A type of cancer that begins in plasma cells (white blood cells that produce antibodies). Also called Kahler disease, myelomatosis, and… »
The heavy chain of the immunoglobulin, IgA, is defective. This is the second most common type of multiple myeloma (~20%). … »
The heavy chain of the immunoglobulin, IgD, is defective. This multiple myeloma subtype is very rare (~1%). »
The heavy chain of the immunoglobulin, IgE, is defective. This multiple myeloma subtype is extremely rare. »
The heavy chain, IgG, of the immunoglobulin is defective. This is the most common type of multiple myeloma (>50%). »
The heavy chain, IgM, of the immunoglobulin is defective. This finding is seen in other lymphocytic/plasmacytic disorders as well, including Waldenstrom… »
Only the light chain (kappa or lambda) of the immunoglobulin is defective. »
Point mutations at various locations in a DNA sequence from either a eukaryotic or prokaryotic organism that causes a base change which… »
Complete impairment of two or more organs or organ systems. »
A neoplastic chondrogenic process affecting multiple sites. Grossly and microscopically it resembles an osteochondroma. »
A gestation with more than one fertilized egg implanted as a viable fetus in the uterus. »
A disorder of the central nervous system marked by weakness, numbness, a loss of muscle coordination, and problems with vision, speech, and… »
A rare genetic neoplastic disorder with an autosomal dominant pattern of inheritance characterized by multiple, recurrent skin cancers that spontaneously resolve. It… »
A morphologic finding referring to the presence of multiple foci of serpentine necrosis and glial cell perivascular pseudopalisading in a glioma. … »
Multiple meningiomas that affect the skull base. »
A rare autosomal recessive lysosomal storage disease caused by mutations in SUMF1 gene. It is characterized by deficiency of all sulfatase… »
A rare neurodegenerative disorder characterized by loss of autonomic nervous system functions and disturbances of motor, balance and muscle coordination. »
A method of obtaining descriptive parameters having physiological significance from plots whose points at various times are computed from dynamic scan data… »
Multiple point mutations in a DNA sequence from eukaryotic or prokaryotic organisms in which each mutation occurs by substitution of a purine… »
Multiple point mutations in a DNA sequence from eukaryotic or prokaryotic organisms in which each mutation occurs by substitution of a purine… »
A laboratory test in which many genes are studied in a sample of tissue. Multiple-gene panel tests may help find mutations (changes)… »
A laboratory test in which many genes are studied in a sample of tissue. Multiple-gene tests may help find mutations (changes) in… »
Proceso mediante el cual se copia el ADN de una célula antes de que esta se multiplique. »
An arithmetic operation by which the product of two numbers is computed, symbolized by x or *. »
A quantity obtained by multiplication. »
Gran número o variedad. »
A large number or variety. »
A number by which another number is multiplied. »
A device designed to take an input and increase some characteristic of it. »
To combine or increase by multiplication. »
A nerve cell with several processes, usually an axon and three or more dendrites. »
Having the ability to develop into more than one cell type of the body. See also pluripotent and totipotent. »
A specialized, self-renewing cell in the bone marrow that has the capacity to differentiate into a cell with a particular function. … »
A specialized, self-renewing cell in the bone marrow that has the capacity to differentiate into a cell with a particular function, but… »
A cell that can only differentiate to a particular type of cells (e.g. hematopoietic cells or epithelial cells). --2005 »
A standard file format for transferring non-textual data over the internet. »
Having ancestors of several or various races. »
A substance being studied in the treatment of several types of cancer. Multitargeted receptor tyrosine kinase inhibitor ABT-869 blocks the action of… »
An orally bioavailable, small-molecule, multitargeted reversible tyrosine kinase inhibitor with potential antineoplastic activity. Multitargeted tyrosine kinase inhibitor JNJ-26483327 binds to and inhibits… »
An orally bioavailable, small-molecule, multitargeted tyrosine kinase inhibitor with potential antineoplastic activity. Multitargeted tyrosine kinase inhibitor MGCD265 binds to and inhibits the… »
A capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity. Multitargeted tyrosine… »
An orally bioavailable small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. XL647 binds to and inhibits several tyrosine receptor kinases… »
A normal distribution which models more than one variable of interest. The parameters of the multivariate normal distribution include the mean and… »
A membrane-bound vesicle that encompasses several smaller membrane-bound vesicles. »
A dietary supplement containing all or most of the vitamins that may not be readily available in the diet. Vitamins may be… »
A dietary supplement containing all or most of the vitamins and some minerals which may not be readily available in the… »
A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due… »
A type of paramyxovirus. It spreads from person to person through coughs, sneezes and saliva, as well as through contact with contaminated… »
A type of bean grown in warm climates, usually for its seed and for bean sprouts. Mung bean may have anticancer… »
A political unit, such as a city, town, or village, incorporated for local self-government. »
A complete device charged with explosives, propellants, pyrotechnics, initiating composition, or nuclear, biological, or chemical material for use in military operations, including… »
A natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl tRNA… »
The calcium salt form of mupirocin, a natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific… »
A dual peroxisome proliferator-activated receptor (PPAR) agonist, with hypoglycemic activity. Muraglitazar causes an increase in HDL-C levels, and a decrease in total… »
Medicamento en estudio para el tratamiento de adultos jóvenes con cáncer de hueso que ha empeorado o ha reaparecido. El muramil tripéptido… »
A naturally occurring component of bacterial cell walls that has the capacity to activate macrophages. »
A drug being studied in the treatment of young adults with bone cancer that has gotten worse or come back. Muramyl tripeptide… »
A water-soluble prodrug, consisting of camptothecin covalently linked to polymeric backbone methacryloylglycynamide, with potential antineoplastic activity. After entering tumor cells, the active… »
Taxonomic family which includes mice, rats, and gerbils. »
Erythrocytes with protoplasmic projections giving the cell a thorny appearance. »
any of the cells lining an acinus; acinus is a general term used to designate a small saclike dilatation, particularly one found… »
The outer layer of the adrenal gland. It secretes mineralocorticoids, androgens, and glucocorticoids. »
Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of… »
Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the brain, within the temporal lobe. The… »
The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and… »
The part of the eye anterior to the lens, including but not limited to the anterior chamber, cornea and related structures. … »
The glandular or anterior lobe of the pituitary gland which secretes several hormones. »
The largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many… »
The organs involved with detecting and processing auditory information, including the pinna, external auditory canal, ear drum, middle ear, and inner ear… »
Immunologically important lymphocyte that is not thymus-dependent, is either short-lived and naive or long-lived and of memory phenotype, and resembles the bursa-derived… »
Mucus-secreting glands situated on the posterior and lateral aspect of the vestibule of the vagina. »
Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic… »
Any of the ducts conveying bile between the liver and the intestine, including hepatic, cystic, and common bile duct. »
Blast cells are in an immature (undifferentiated) stage in cellular development, occurring before the appearance of the definitive characteristics exhibited by fully… »
One of the cells of the blood, a leukocyte or erythrocyte. SYN blood corpuscle. »
breast. 1. The pectoral surface of the thorax. 2. The organ of milk secretion; one of two hemispheric projections of variable size… »
The part of the conjunctiva, a thin transparent mucous membrane, that is loosely attached the orbital septum and covers the anterior surface… »
Human colonic adenocarcinoma cells that are able to express differentiation features characteristic of mature intestinal cells, such as enterocytes or mucus… »
Cells of, or derived from, a malignant tumor. »
The paired upper chambers of the heart. The left atrium receives oxygenated blood from the pulmonary vein and pumps blood into… »
A small epidermoid structure of the conjunctiva of the eye that lies near the inner canthus. It serves as a transition… »
CD8+ T lymphocytes are one type of T-lymphocyte which bears the CD8 molecular marker on its cell surface. Some CD8 cells recognize… »
The smallest units of living structure capable of independent existence, composed of a membrane-enclosed mass of protoplasm and containing a nucleus or… »
That portion of the nervous system consisting of the brain and spinal cord. (Dorland, 28th ed) (MSH98) »
Epithelial cells that line the basal half of the gastric glands. Chief cells synthesize and secrete pepsinogen, a precursor of the enzyme… »
Polymorphic cells that form cartilage. »
A villous structure of tangled masses of BLOOD VESSELS contained within the third, lateral, and fourth ventricles of the BRAIN. It regulates… »
A tumor progenitor cell. »
The part of the internal ear that is concerned with hearing. It forms the anterior part of the labyrinth, is conical, and… »
Bile ducts are passageways that carry bile. Two major bile ducts come together into a "trunk"-the common bile duct which empties into… »
A thin, transparent mucous membrane that covers the posterior surface of lids (palpebral conjunctiva) and the outer surface of the sclera (bulbar… »
A group of cells that includes FIBROBLASTS, cartilage cells, ADIPOCYTES, smooth muscle cells, and bone cells. »
The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous epithelium, Bowman's membrane, stroma, Descemet's… »
The hollow muscular organ in which the impregnated ovum is developed into the child; it is about 7.5 cm in length in… »
A hybrid cell with cytoplasm (or cytoplasmic components) of one cell inserted into another cell. »
Dendritic Cells are immunocompetent cells of the lymphoid and hemopoietic systems and skin. They function morphologically and phenotypically by presenting or processing… »
The paired caudal parts of the prosencephalon from which the THALAMUS, HYPOTHALAMUS, EPITHALAMUS, and SUBTHALAMUS are derived. »
encompasses the mouth, esophagus, stomach, intestines, biliary tract, pancreas, liver, and associated hormones and secretions. »
Sensory ganglia located on the dorsal spinal roots within the vertebral column. The spinal ganglion cells are pseudounipolar. The single primary branch… »
The organ of hearing: composed of the external ear, which includes the auricle and the external acoustic, or auditory, meatus; the middle… »
Embryonic stem cells are pluripotent and can give rise to all of the different types of specialized cells in the body but… »
The innermost layer of the heart, comprised of endothelial cells. »
Ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. (MSH98) … »
The inner of the three germ layers of the embryo. »
One of the squamous cells forming the lining of blood and lymph vessels and the inner layer of the endocardium. SYN… »
Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round… »
A thin membrane that lines the ventricles of the brain and the central canal of the SPINAL CORD. »
A thin fibrous membrane that covers the outer surface of the anteriors sclera and contains blood vessels which supply the sclera. … »
The dorsal posterior subdivision of the diencephalon. The epithalamus is generally considered to include the habenular nuclei (HABENULA) and associated fiber bundles,… »
Cells that cover the surface of the body and line its cavities. »
Characteristic cells of granulomatous hypersensitivity. They appear as large, flattened cells with increased endoplasmic reticulum. They are believed to be activated macrophages… »
Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing hemoglobin whose function is to transport oxygen. »
The portion of the digestive canal between the pharynx and stomach. It is about 25 cm long and consists of three parts:… »
A tubular structure that runs from the middle ear to the nasopharynx and is approximately 3-4 cm length. Its lumen is roughly… »
A gland from which secretions reach a free surface of the body by ducts. »
That part of the ear canal external to the ear drum »
Two long muscular tubes that transport ova from the ovaries to the uterus. They extend from the horn of the uterus to… »
The longest and largest bone of the skeleton, it is situated between the hip and the knee. »
Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules. »
Antigen Presenting Cells (APCs) located in the follicles of secondary lymphoid organs. These dendritic cells are unique because of their location,… »
The paired, mucosal lined air spaces located above the orbit and communicating with the nasal passages. »
Clusters of multipolar neurons surrounded by a capsule of loosely organized CONNECTIVE TISSUE located outside the CENTRAL NERVOUS SYSTEM. »
All the organs involved in reproduction and the formation and release of URINE. It includes the kidneys, ureters, BLADDER, URETHRA, and the… »
The germ cells, collectively as distinguished from the somatic cells or soma, are the reproductive cells of the body, specifically, either egg… »
The vocal apparatus of the larynx, consisting of the true vocal cords (plica vocalis) and the opening between them (rima glottidis). … »
Leukocytes with abundant granules in the cytoplasm. They are divided into three groups: NEUTROPHILS, EOSINOPHILS, and BASOPHILS. »
Non-encapsulated accumulations of lymphoid tissue in the alimentary tract that form a secretory immune system containing cells committed to IgA or IgE… »
The epithelium which lines the intestinal tract. »
For oncology, area of the body generally construed to comprise base of skull and facial bones, sinuses, orbits, salivary glands, oral cavity,… »
A parenchymal liver cell. »
A macrophage present in connective tissue. »
Hypothalamus is an important supervisory center in the brain, rich in ganglia, nerve fibers, and synaptic connections. It is composed of several… »
The complex group of organs like thymus, spleen, tonsils, lymphatic system, hematopoetic system and cells like lymphocytes, granulocytes, monocytes and macrophages that… »
An intracranial venous sinus that lies in a midline location along the lower free border of the falx cerebri of the… »
The venous trunk which receives blood from the lower extremities and from the pelvic and abdominal organs. »
The internal ear; the essential part of the organ of hearing. It consists of an osseous and a membranous portion. »
nodes that lie along the course of a lymphatic vessel between a primary melanoma site and a recognized node field. (from Medscape)… »
Arteries which have their origins within the intracranial cavity. »
The brain, intracranial portions of the cranial nerves, intracranial blood vessels, intracranial meninges and other surrounding and supporting structures contained with the… »
The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the… »
Veins in the neck which drain the brain, face, and neck into the brachiocephalic or subclavian veins. »
Epidermal cells which synthesize keratin and undergo characteristic changes as they move upward from the basal layers of the epidermis to the… »
Dendritic clear cells in the epidermis, containing distinctive granules that appear rod- or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes;… »
The nine cartilages of the larynx, including the cricoid, thyroid and epiglottic, and two each of arytenoid, corniculate and cuneiform. »
The rostral extensions of the ventricular system of the brain consisting of two cavities, one on each side of the brain within… »
A biconvex transparent structure of the eye through which light is focused on the retina. The lens sits behind the iris… »
not classifiable to C16.1 to C16.4 »
Either of the two fleshy, full-blooded margins of the mouth. »
The cells of the corpus luteum which are derived from the granulosa cells and the theca cells of the Graafian follicle. … »
Blast cells are in an immature (undifferentiated) stage in cellular development, occurring before the appearance of the definitive characteristics exhibited by fully… »
White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the… »
Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the… »
Cytolytic lymphocytes with the unique capacity of killing natural killer (NK)-resistant fresh tumor cells. They are interleukin-2-activated NK cells that have no… »
The male reproductive organs. They are divided into the external organs (penis, scrotum, and urethra) and the internal organs (testis, epididymis, ductus… »
A cell originating from or isolated from an animal of class Mammalia. »
A honeycombed section of bone located near the base of the skull, protruding behind the outer ear. It is connected to… »
An immunotoxin consisting of a murine monoclonal antibody (MCA) conjugated to the toxin ricin. The monoclonal antibody component binds to cell surface… »
The lower portion of the brainstem located between the pons and brainstem. This structure contains several descending and ascending tracts, lower… »
Very large bone marrow cells which release mature blood platelets. »
Epidermal dendritic pigment cells which control long-term morphological color changes by alteration in their number or in the amount of pigment they… »
Chromatophores (large pigment cells of fish, amphibia, reptiles and many invertebrates) which contain melanin. Short term color changes are brought about by… »
Modified epidermal cells located in the stratum basale. They are found mostly in areas where sensory perception is acute, such as the… »
The middle germ layer of the embryo. »
The five long bones of the METATARSUS articulating with the TARSAL BONES proximally and the TOES (phalanges) distally. »
The uppermost portion of the brainstem located between the pons and the diencephalon. The midbrain contains the cerebral peduncles, oculomotor, trochlear… »
The valve between the left atrium and left ventricle of the heart. »
A mouse monoclonal antibody that was raised against human epidermal growth factor (EGF) receptor. Antibody 225 competes with EGF or transforming growth… »
A murine monoclonal antibody directed against the CD20 phosphoprotein, expressed on the cell surface of normal B-lymphocytes and B-cell lymphomas. »
A murine monoclonal antibody directed against human colorectal carcinoma-associated cell-surface antigen D612. »
Large, phagocytic mononuclear leukocytes produced in the vertebrate bone marrow and released into the blood; contain a large, oval or somewhat indented… »
Monocytes made cytotoxic by ex vivo incubation with cytokines, especially interferon-gamma. AKM cells are used for adoptive immunotherapy in cancer patients. … »
Cells which include the MONOCYTES and the GRANULOCYTES. »
One of the two stem cells derived from HEMATOPOIETIC STEM CELLS - the other being the lymphoid progenitor cell. Derived from these… »
The muscle tissue of the HEART composed of striated, involuntary muscle known as cardiac muscle. »
Natural killer cells are large granular lymphocytes which do not express markers of either T or B cell lineage. These cells do… »
The entire nerve apparatus, composed of a central part, the brain and spinal cord, and a peripheral part, the cranial and spinal… »
The components of the eye that are also part of the nervous system, including the retina and optic nerve. »
An embryonic nerve cell capable of differentiating into a neuron. »
The non-neuronal cells of the nervous system. They are divided into macroglia (ASTROCYTES, OLIGODENDROGLIA, and SCHWANN CELLS) and MICROGLIA. They not only… »
Any of the conducting cells of the nervous system. A typical neuron consists of a cell body, containing the nucleus and the… »
A specialized structure that serves as an organ of the sense of smell as well as part of the respiratory system; the… »
The 1st cranial nerve. The olfactory nerve conveys the sense of smell. It is formed by the axons of OLFACTORY RECEPTOR NEURONS… »
Neurons in the olfactory epithelium with proteins (RECEPTORS, ODORANT) that bind, and thus detect, odorants. Olfactory receptor neurons are bipolar. They send… »
A class of neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal satellite cells according… »
The 2nd cranial nerve. The optic nerve conveys visual information from the retina to the brain. The nerve carries the axons of… »
The bony cavity of the skull which contains the eye, anterior portion of the optic nerve, ocular muscles and ocular adnexa. … »
is an anatomical structure that consists of all members of one or more organ subclass; these members are interconnected by anatomical structures… »
Mature osteoblasts that have become embedded in the BONE MATRIX. They occupy a small cavity, called lacuna, in the matrix and are… »
The part of the conjunctiva, a thin transparent mucous membrane, that covers the posterior surface of the eyelids. »
A mixed exocrine and endocrine gland situated transversely across the posterior abdominal wall in the epigastric and hypochondriac regions. The endocrine portion… »
Ducts that collect PANCREATIC JUICE from the PANCREAS and supply it to the DUODENUM. »
Epithelial cells found in the basal part of the intestinal glands (crypts of Lieberkuhn). Paneth cells synthesize and secrete lysozyme and… »
Two small paired endocrine glands located in the posterior region of the thyroid gland. Principle cell types include chief cells and… »
Slender, contractile, mesenchymal-like cells found in close association with capillary walls. They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth… »
The lower part of the abdomen that contains the intestines (the last part of the digestive tract), the stomach, and the… »
Lymphoid tissue on the mucosa of the small intestine. »
The muscles of the pharynx are the inferior, middle and superior constrictors, salpingopharyngeus, and stylopharyngeus. »
Cells specialized to detect and transduce light. Rods and cones are the photoreceptors in the vertebrate retina. »
A small conical midline body attached to the posterior part of the third ventricle and lying between the superior colliculi, below the… »
A small, unpaired gland situated in the sella turcica tissue. It is connected to the hypothalamus by a short stalk. »
Specialized forms of antibody-producing B-LYMPHOCYTES. They synthesize and secrete immunoglobulin. They are found only in lymphoid organs and at sites of immune… »
The middle portion of the brainstem located between the midbrain and the medulla oblongata. The fourth ventricle lies dorsal to the… »
The neural or post-neural lobe of the pituitary gland which stores and releases vasopressin, oxytocin, and neurophysins. »
The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border… »
Cells which show sign/s, that they can become cancerous. »
A gland in the male reproductive system just below the bladder. It surrounds part of the urethra, the canal that empties the… »
The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs. »
Splenic pulp seen grossly as a reddish brown substance, due to its abundance of red blood cells, consisting of splenic sinuses and… »
Large cells of unknown origin, usually multinucleate, whose presence is the common histologic characteristic of HODGKIN DISEASE. »
An area occupying the most posterior aspect of the abdominal cavity. It is bounded laterally by the borders of the quadratus lumborum… »
A murine retrovirus that contains plasmid DNA (cDNA) coding for the B chain of platelet-derived growth factor (PDGFB). Overexpressed in some… »
Large single cells, either cylindrical or prismatic in shape, that form the basic unit of muscle tissue. They consist of a soft… »
Neuroglial cells of the peripheral nervous system which form the insulating myelin sheaths of peripheral axons. »
The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is… »
Supporting cells found in the seminiferous tubules of the testes in mammals. They surround and nourish developing sperm cells. They secrete ANDROGEN-BINDING… »
The natural covering of the body; the skin. »
A lymphoid cell of follicular center cell origin that has an irregularly shaped nucleus with clumped chromatin, absent nucleoli, and one or… »
The 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment. The… »
Cells of the spleen. »
An epithelium in which the cells are flattened. May be simple (e.g. Endothelium) or stratified (e.g. Epidermis). (On-line Medical Dictionary) »
Primitive blood cells derived from embryonic mesenchyme capable of differentiating into any of the blood cell line progenitor cells (erythroblasts, young granulocytic… »
The mouth, teeth, jaws, pharynx, and related structures as they relate to mastication, deglutition, and speech. »
The part of the epidermis layer of the skin containing Langerhans cells, which are dendritic, MHC class II-expressing antigen presenting cells. … »
The supporting connective tissue of an organ. (see also parenchyma) »
Connective tissue cells of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and… »
The continuation of the axillary vein which follows the subclavian artery and then joins the internal jugular vein to form the brachiocephalic… »
An intracranial venous sinus that lies in a superior and midline location above the interhemispheric fissure along the superior border of the… »
The upper part of the larynx, including the epiglottis; the area above the vocal cords. »
A thymocyte-derived lymphocyte of immunological importance that is long-lived (months to years) and is responsible for cell-mediated immunity. T lymphocyte cells form… »
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC),… »
Subpopulation of CD4+ lymphocytes which induce CD8+ suppressor T-cells (T-LYMPHOCYTES, SUPPRESSOR-EFFECTOR) to suppress antibody production by B-cells. They also stimulate other cellular… »
Type 1 Helper Cells are a subset of helper-inducer T-lymphocytes which synthesize and secrete interleukin-2, gamma-interferon, and interleukin-12. Due to their ability… »
Type 2 Helper Cells are a subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These… »
A centrally placed component of the ventricular system of the brain located in the diencephalon. Cerebrospinal fluid from the lateral ventricles… »
A cell that develops in the thymus, seemingly from a stem cell of bone marrow and of fetal liver, and is the… »
A highly vascular endocrine gland consisting of two lobes, one on either side of the trachea, joined by a narrow isthmus; it… »
Totipotent stem cells, such as the product of fertilization of an ovum and its progeny, are stem cells that have total potency… »
Trachea -The cartilaginous and membranous tube descending from the larynx and branching into the right and left main bronchi. Bronchi-The larger air… »
The 4th cranial nerve. The trochlear nerve carries the motor innervation of the superior oblique muscles of the eye. »
Cells of, or derived from, a tumor. »
Colony-forming cells which give rise to neoplasms. »
New blood vessels formed by solid tumors. »
A thin membrane that separates the external auditory canal from the middle ear. The movement of the tympanic membrane in response… »
A plasmid DNA vaccine encoding the mouse tumor associated antigen tyrosinase-related protein-2 (TYRP2) with potential immunostimulating and antineoplastic activities. Upon administration, murine… »
One of the bones that comprise the forearm. The largest aspect articulates with the humerus at the elbow joint and the smallest… »
A developmental defect characterized by failure of the testes to descend into the scrotum. (Dorland, 27th ed) »
The appendages of the UTERUS: the FALLOPIAN TUBES, OVARIES, and supporting ligaments of the uterus. »
The hollow muscular organ in which the impregnated ovum is developed into the child; it is about 7.5 cm in length in… »
Duct carrying spermatozoa. »
Four connected cavities (hollow spaces) in the brain. »
The eighth cranial nerve composed of the acoustic nerve and the vestibular nerve. The nerve travels from the inner ear, enters… »
Two small bands of muscle within the larynx. They close to prevent food from getting into the lungs, and they vibrate to… »
The part of the spleen that consists of nodules and other lymphatic concentrations. »
The fertilized ovum. »
A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to… »
Tipo de anticuerpo monoclonal utilizado para detectar y tratar el cáncer. Los anticuerpos monoclonales son sustancias que se producen en el laboratorio… »
The common house mouse, often used as an experimental organism. »
A subspecies of common house mouse (Mus musculus). »
A species of mouse in the Muridae family found in northern Africa, Portugal, Spain, and France. »
A nutritional supplement containing an extract of the skin of Muscadine grape (Vitis rotundifolia), with anti-inflammatory, antioxidant and potential chemopreventive activities. The… »
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The muscarinic cholinergic receptor 1 is involved in mediation… »
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The muscarinic cholinergic receptor 3 controls smooth muscle contraction… »
Cholinergic Receptor, Muscarinic 4, encoded by the human CHRM4 gene, is a G protein-coupled receptor. The muscarinic cholinergic receptors belong to a… »
Muscarinic acetylcholine receptor M5 protein (532 aa, 60 kD) is a cell communication process protein that is encoded by the human CHRM5… »
A liquid, oromucosal formulation containing a muscarinic agonist with potential anti-xerostomia activity. Upon application to the inside lining of the mouth, muscarinic… »
A process that involves the non-covalent interaction of acetylcholine with one of the five muscarinic receptors. These interactions play a role in… »
One of the contractile organs of the body. »
The loss of muscle tissue due to inactivity or disease. »
Removal of tissue from the muscle, for microscopic examination. »
A connective tissue cell with the ability to convert chemical energy into mechanical energy via a contractile apparatus. As part of the… »
A morphologic finding indicating the presence of enlarged muscle cells in a muscle tissue sample. »
The process where thick (myosin) and thin (actin) filaments slide against each other to produce a shortening or tensing of the muscle… »
Permanent contraction of a muscle as a result of spasm or paralysis. »
A sharp pain that occurs when a muscle suddenly contracts (tightens up). Cramps commonly occur in the abdomen and legs. »
Muscle cramps are sudden, involuntary contractions or spasms in one or more of your muscles. They often occur after exercise or at… »
Your muscles help you move and help your body work. Different types of muscles have different jobs. There are many problems that… »
Skeletal muscle fibers having high myofibrillar ATPase activity, high glycolytic enzyme activities, and an intermediate glycogen content which produce a fast… »
Skeletal muscle fibers having low myofibrillar ATPase activity, low glycogen content, and high myoglobin content, high mitochondrial oxidative enzyme activities, and an… »
The smooth muscle component of an organ, especially of a hollow organ or tubular structure. »
Muscles arising in the zygomatic arch that close the jaw. »
The physiology of muscle contraction »
A special subset of proteins whose roles are directly related to the function of muscle cells. This group is comprised of both… »
Any agent that relaxes skeletal muscles and reduces muscle contraction. »
Synthetic compounds or mixtures with muscle relaxant activity. A muscle relaxant preparation is used to prevent muscle spasms by inhibiting muscle contractions… »
A sudden, violent, involuntary contraction of a muscle or group of muscles. »
The Muscle Spindle is composed of intrafusal fibers that are located within and run parallel to the extrafusal fibers of skeletal… »
Tissue responsible for the body movements and the shape and size changes of interna organs. Muscle tissue is composed of specialized… »
A component of the Apgar score, it is the numerical value assigned to an assessment of the residual muscle tension of a… »
A weakening, shrinking, and loss of muscle caused by disease or lack of use. Muscle wasting decreases strength and the ability to… »
A reduction in the strength of one or more muscles. »
A reduction in the strength of the muscles in the left side of the body. »
A reduction in the strength of the lower limb muscles. »
A reduction in the strength of the muscles in the right side of the body. »
A reduction in the strength of the trunk muscles. »
A reduction in the strength of the upper limb muscles. »
Muscle, skeletal receptor tyrosine-protein kinase (869 aa, ~97 kDa) is encoded by the human MUSK gene. This protein is involved in receptor… »
A group of inherited progressive muscle disorders characterized by muscle weakness and eventual death of the muscle tissues. Examples include Duchenne muscular… »
Stiffness or inflexibility. »
An involuntary, compulsive, repetitive stereotyped movement, usually of the face or shoulders. »
A thin layer of smooth muscle fibers found as a part of the tunica mucosa in the gastrointestinal tract and urinary bladder… »
The detrusor muscle of the bladder, forming the muscular wall of the bladder, consisting of the inner longitudinal; middle circular; and outer… »
Musculin (206 aa, ~22 kDa) is encoded by the human MSC gene. This protein plays a role in both transcriptional regulation and… »
Having to do with muscles, bones, tendons, ligaments, joints, and cartilage. »
Congenital or acquired deformity of the musculoskeletal system. »
Symptoms, physical examination results, and/or laboratory rest results related to the muscles and bones. »
A subject domain utilized for the submission of information encompassing and representing data, vocabulary or records related to musculoskeletal findings, connective and… »
Damage to the muscles, bones and their supportive structral attachments. »
Discomfort referable to either the muscles or the bones themselves. »
A Musculoskeletal Process consists of a function of cellular, cell, or tissue components of the organ system comprised of muscle, bone, and… »
The system of muscles, tendons, ligaments, bones, joints and associated tissues that move the body and maintain its form. »
A category of diseases that involve muscles and bones. »
Any component of the system of muscles, tendons, ligaments, bones, joints and associated tissues that move the body and maintain its… »
A triangular muscle in the back, connected to the vertebral column, arm, and shoulder. Its action involves adduction, medial rotation, and extension… »
A method used to treat impotence (inability to have an erection). A suppository, in the form of a very small pellet, is… »
Método que se usa para tratar la impotencia (incapacidad de tener una erección). Se introduce un supositorio muy pequeño en forma de… »
A lesion having the shape of a mushroom. »
Treatment that uses music to help relieve pain or stress and promote well-being. It is being studied in the treatment of several… »
Tratamiento para el que se usa música para ayudar a aliviar el dolor o la tensión, y para mejorar el bienestar. Está… »
This gene plays a role in receptor tyrosine kinase signal transduction and in neuronal synapse function. »
Human MUSK wild-type allele is located within 9q31.3-q32 and is approximately 132 kb in length. This allele, which encodes muscle, skeletal receptor… »
A religious group that follows the words and belief system founded by the prophet Muhammad and are written in the Koran. … »
A blistering agent primarily containing sulfur and chlorine groups that alkylates DNA to form DNA crosslinks, causing inhibition of DNA synthesis. … »
A pale yellow, oily, highly toxic, volatile, liquid alkylating compound with a sweet to garlic-like odor that evaporates to a poisonous… »
The vegetable oil pressed from seeds or the essential oil extracted from the seeds of Brassica nigra, Brassica juncea, or Brassica… »
A mustard compound that gets converted to an active mustard alkylating agent at a tumor site, causing DNA cross-linking. These compounds may… »
A drug used to treat non-Hodgkin lymphoma, advanced Hodgkin lymphoma, chronic leukemia, mycosis fungoides, and a type of lung cancer called bronchogenic… »
Medicamento que se usa para tratar el linfoma no Hodgkin, el linfoma de Hodgkin en estadio avanzado, leucemia crónica, micosis fungoide, … »
Taxonomic family which includes the Ferret. »
Medicamento que se usa para tratar el linfoma no Hodgkin, el linfoma de Hodgkin en estadio avanzado, leucemia crónica, micosis fungoide, … »
A drug used to treat non-Hodgkin lymphoma, advanced Hodgkin lymphoma, chronic leukemia, mycosis fungoides, and a type of lung cancer called bronchogenic… »
Cualquier cambio en la secuencia del ADN de una célula. Las mutaciones podrían ser el resultado de errores durante la multiplicación… »
Mutación específica (cambio) en el gen BRAF, que elabora la proteína que participa en el envío de señales en las células y… »
Cambio genético en las células reproductoras del cuerpo (óvulo o espermatozoide) que se incorpora en el ADN de cada célula del cuerpo… »
Cambio genético en las células reproductoras del cuerpo (óvulo o espermatozoide) que se incorpora en el ADN de cada célula del cuerpo… »
Alteración del ADN que ocurre después de la concepción. Las mutaciones somáticas se pueden presentar en cualquiera de las células del cuerpo,… »
Anything that causes a mutation (a change in the DNA of a cell). DNA changes caused by mutagens may harm cells and… »
Production of genetic alterations by any technique, including chemicals, radiation, recombination, or other molecular biology methods. »
Cualquier cosa que causa una mutación (cambio en el ADN de una célula). Los cambios que los mutágenos causan en el ADN… »
A drug used to treat advanced cancer of the stomach and pancreas that has not gotten better with other treatment. It is… »
Medicamento que se usa para tratar el cáncer de estómago y el cáncer de páncreas avanzados que no mejoraron con otro… »
An altered form of an individual, organism, population, or genetic character that differs from the corresponding wild type due to one or… »
A cancer vaccine consisting of autologous dendritic cells which have been pulsed with a mutant p53 peptide. Vaccination with mutant p53 peptide… »
Cambiar el material genético de una célula. Los cambios (mutaciones) pueden ser nocivos, beneficiosos o no tener efecto. »
To change the genetic material of a cell. The changes (mutations) can be harmful, beneficial, or have no effect. »
Point-mutation products of Ras proto-oncogene are found to associated with a broad spectrum of human carcinomas. Mutation locations are notably at… »
Any change in the DNA sequence of a cell. Mutations may be caused by mistakes during cell division, or they may be… »
Any transmissible change in the genetic material of an organism, which can result from radiation, viral infection, transposition, treatment with mutagenic chemicals… »
A procedure to test for the presence of a specific mutation or a set of mutations as opposed to complete gene sequencing… »
A person who has a mutated (changed) copy of a gene. This change may cause a disease in that person or in… »
The detection by physical, chemical, or biological means of an altered DNA sequence. Includes SSCP, DNA sequencing, hybridization, and reporter gene… »
In avoiding recognition and removal by the mismatch repair system, a Mutation Fixation involves stabilization of a DNA sequence alteration in both… »
The range of mutations that have occurred to a gene, or at a specific locus. »
MutS Homolog 4, a 105-kD protein encoded by the MSH4 gene, belongs to the DNA mismatch repair muts family and is involved… »
Referring to anything in which both parties have reciprocal rights, understanding or agreement. »
Expresses the extent to which the observed frequency of co-occurrence differs from that expected under the null hypothesis. »
Characterized or delimited reciprocally, in a mutual or shared manner. »
This gene plays a role in the repair of oxidative DNA damage. »
A molecular genetic abnormality that refers to the mutation of the MUTYH gene on chromosome 1p34.1. »
Human MUTYH allele is located within 1p34.3-p32.1 and is approximately 92 kb in length. This allele, which encodes A/G-specific adenine DNA glycosylase… »
An autosomal recessive hereditary neoplastic syndrome caused by mutations in the MUTYH gene on chromosome 1p34.1. It is characterized by the… »
A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain… »
A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the suicide gene FCU1 with potential antineoplastic… »
A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with… »
A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding genes for prostate specific antigen (PSA) and prostate… »
A regimen consisting of methotrexate, vinblastine, doxorubicin and cisplatin used for the treatment of advanced-stage bladder cancer. »
A brand of cryofreezers designed to store samples in liquid nitrogen or vapor phase liquid nitrogen. »
A combination peptide vaccine of 2 chimeric peptides of the promiscuous T cell epitope derived from measles virus fusion protein (MVF; amino… »
A chimeric peptide immunogen of human epidermal growth factor-2 (HER-2) with antineoplastic property. HER-2 protein is a receptor tyrosine kinase and a… »
This gene plays a role in vault ribonucleoprotein complex structure. »
Human MVP wild-type allele is located in the vicinity of 16p11.2 and is approximately 28 kb in length. This allele, which encodes… »
A distant metastasis TNM finding indicating that the status of distant metastasis cannot be assessed. »
This gene plays a role in GTP hydrolysis, interferon signaling and apoptosis. »
Human MX1 wild-type allele is located in the vicinity of 21q22.3 and is approximately 39 kb in length. This allele, which encodes… »
This gene plays a role in GTP hydrolysis. »
Human MX2 wild-type allele is located in the vicinity of 21q22.3 and is approximately 46 kb in length. This allele, which encodes… »
This gene is involved in repression of transcription. »
Human MXD1 wild-type allele is located within 2p13-p12 and is approximately 28 kb in length. This allele, which encodes MAD protein, plays… »
This gene plays a role in regulation of transcription and mitosis. It is also involved in terminal differentiation. »
Human MXI1 wild-type allele is located within 10q24-q25 and is approximately 80 kb in length. This allele, which encodes MAX-interacting protein 1,… »
Pain in a muscle or group of muscles. »
Any ocular weakness. All other muscles strength is normal. »
Mild weakness affecting non-ocular muscles. May also have ocular muscle weakness. »
Moderate weakness affecting non-ocular muscles. May also have ocular muscle weakness. »
Severe weakness affecting non-ocular muscles. May also have ocular muscle weakness. »
Severe muscle weakness that requires intubation, with or without mechanical ventilation. »
A classification system for grading myasthenia gravis that divides the disease into 5 main classes and several subclasses. »
A disease in which antibodies made by a person’s immune system prevent certain nerve-muscle interactions. It causes weakness in the arms and… »
This gene plays a role in hematopoietic cell proliferation and development. »
Human MYB Oncogene Protein is a product of a mutated variant (Oncogene MYB) of MYB Gene, which encodes 6 alternative isoforms of… »
Human MYB wild-type allele is located within 6q22-q23 and is approximately 38 kb in length. This allele, which encodes Myb proto-oncogene protein,… »
Myb-binding protein 1A (1328 aa, ~149 kDa) is encoded by the human MYBBP1A gene. This protein is involved in transcriptional regulation. … »
Myb-related protein A (752 aa, ~86 kDa) is encoded by the human MYBL1 gene. This protein plays a role in transcriptional… »
Myb-related protein B (700 aa, ~79 kDa) is encoded by the human MYBL2 gene. This protein is involved in the regulation of… »
This gene plays a role both as an activator and repressor of transcription. »
Human MYBBP1A wild-type allele is located in the vicinity of 17p13.3 and is approximately 16 kb in length. This allele, which encodes… »
This gene plays a role in transcriptional regulation and cellular differentiation. »
Human MYBL1 wild-type allele is located in the vicinity of 8q22 and is approximately 51 kb in length. This allele, which encodes… »
This gene plays a regulatory role in cell cycle progression. »
Human MYBL2 wild-type allele is located in the vicinity of 20q13.1 and is approximately 49 kb in length. This allele, which encodes… »
MYC boxes I and II, found in the N termini of all members of the MYC protein family, function to direct the… »
MYC Family Genes encode MYC Family Proteins, class III bHLH leucine zipper transcription factors having cellular proliferative and apoptotic roles. Dimerization via… »
MYC family proteins exhibit sequence homology with the transcription factor MYC protooncogene. »
This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and… »
Myc proto-oncogene protein (439 aa, ~49 kDa) is encoded by the human MYC gene. This protein plays a role in the regulation… »
Human MYC wild-type allele is located in the vicinity of 8q24.21 and is approximately 5 kb in length. This allele, which encodes… »
Variants of proto-oncogenes that are members of the MYC family of early response genes, which encode regulatory proteins that act as homo-… »
This gene may play a role in both ubiquitination and transcriptional regulation. »
Human MYCBP2 wild-type allele is located in the vicinity of 13q22 and is approximately 282 kb in length. This allele, which encodes… »
The mass of interwoven filamentous hyphae that forms especially the vegetative portion of the thallus of a fungus. »
A chronic granulomatous inflammation involving the deep dermis and the subcutaneous tissues. It is caused by fungi and actinomycetes. »
This gene is involved in transcriptional regulation and is frequently amplified in small-cell lung cancer. »
Human MYCL1 wild-type allele is located in the vicinity of 1p34.2 and is approximately 7 kb in length. This allele, which encodes… »
A laboratory test in which tumor or bone marrow cells are checked to see how many copies of the MYCN gene are… »
This gene is involved in transcriptional regulation and amplification of this gene is associated with a variety of tumors, most notably… »
Human MYCN wild-type allele is located in the vicinity of 2p24.1 and is approximately 6 kb in length. This allele, which encodes… »
This gene may play a role in the transcriptional activation of target genes. »
Human MYCNOS wild-type allele is located in the vicinity of 2p24.1. This allele, which encodes N-cym protein, may play a role in… »
A taxonomic family of bacterium in the phylum Actinobacteria that includes the genus Mycobacterium, among others. »
A proprietary preparation of mycobacterial DNA oligonucleotides embedded in mycobacterial cell wall fragments derived from cultures of Mycobacterium phlei, with potential immunomodulatory… »
Infections with bacteria of the genus MYCOBACTERIUM. »
Mycobacteria are a type of germ. There are many different kinds. The most common one causes tuberculosis. Another one causes leprosy. Still… »
A PCR-based method for differentiating M. tuberculosis strains based on the number of tandem repeats of the Mycobacterial Interspersed Repetitive Unit. … »
A genus of acid-fast Gram-positive, aerobic and nonmotile bacteria in the phylum Actinobacteria. »
A species of aerobic, Gram positive, rod shaped bacteria assigned to the phylum Actinobacteria. This species is acid-fast, nonmotile, does not reduce… »
A species of Mycobacterium that is a member of the Mycobacterium tuberculosis complex. It is most commonly found in West African countries… »
A species of aerobic, Gram positive, rod shaped bacteria assigned to the phylum Actinobacteria. This species is acid fast, catalase positive, niacin,… »
A group of very similar Mycobacteria consisting of Mycobacterium avium and M. intracellulare. »
Lymph node infection by Mycobacterium avium or Mycobacterium intracellulare. It most often affects children and usually presents with cervical lymph node… »
A species of Mycobacterium that is a member of the Mycobacterium tuberculosis complex. It is the causative agent of tuberculosis in… »
An attenuated form of Mycobacterium bovis that is used to generate the Bacillus Calmette-Guerin vaccine. »
A species of Mycobacterium that is a member of the Mycobacterium tuberculosis complex. It is characterized by smooth, shiny colonies, a shorter… »
A species of aerobic, Gram positive, rods assigned to the phylum Actinobacteria. This species is acid fast, oxidase negative, urease and catalase… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, nonmotile, is unable… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, nonmotile, urease negative… »
A non taxonomic grouping of bacteria assigned to and including related species from the Mycobacterium genus not including those bacteria in the… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, nonmotile, grows on… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, nonmotile, catalase and… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, nonmotile, catalase negative,… »
Any bacterial organism that can be assigned to the species Mycobacterium intracellulare. »
A species of Mycobacterium that can cause tuberculosis and leprosy in mammals, but that is generally not dangerous to healthy people. … »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, stains with carbol… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, nonmotile with optimum… »
A species of Mycobacterium that is a member of the Mycobacterium tuberculosis complex. It is the causative agent of tuberculosis in… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, grows rapidly on… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, nonmotile, acid phosphatase… »
A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, does not grow… »
A species of aerobic, Gram-positive, rod shaped bacteria assigned to the phylum Actinobacteria. This species is acid-fast, grows on MacConkey's agar, is… »
A species of aerobic, Gram-positive, rod shaped bacteria assigned to the phylum Actinobacteria. This species is urease, nitrate reduction, Tween 80 hydrolysis,… »
A species of aerobic, Gram-positive, rod shaped bacteria assigned to the phylum Actinobacteria. This species is acid-fast, positive for nitrate reductase, tellurite… »
A species of aerobic, Gram-positive, rod shaped bacteria assigned to the phylum Actinobacteria. This species is acid-fast, rapidly growing, catalase, urease and… »
An obligate anaerobic, weakly Gram-positive species of mycobacterium that is the cause of most cases of tuberculosis. »
A group of four closely related tuberculosis-causing bacteria: M. bovis, M. africanum, M. canetti and M. microti. »
A measurement of the amount of interferon gamma that is released when Mycobacterium tuberculosis antigen is incubated with a biological specimen, usually… »
The determination of the amount of Mycobacterium tuberculosis nucleic acid present in a sample. »
A species of aerobic, Gram-positive, rod shaped bacteria assigned to the phylum Actinobacteria. This species is acid-fast, catalase, urease and nitrate reduction… »
An attenuated strain of Mycobacterium w, a non-pathogenic, rapidly growing, atypical mycobacterium, with non-specific immunopotentiating properties. In addition to sharing a number… »
A drug used to prevent the spread of a bacterium called in patients with advanced HIV (the virus that causes AIDS)… »
The study of fungus in a nonclinical environment, ie not as a pathogen »
The morpholinoethyl ester of mycophenolic acid (MPA). As an immunosuppressive agent in vivo, the active metabolite mycophenolate reversibly inhibits inosine 5'-monophosphate… »
A drug used to prevent graft-versus-host disease (GVHD) after organ transplants. It is also being studied in the prevention of GVHD after… »
The sodium salt form of mycophenolic acid (MPA), with immunosuppressing activity. In vivo, the active molecule MPA reversibly inhibits inosine monophosphate dehydrogenase… »
An antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate mofetil. … »
A genus of nonmotile facultatively anaerobic bacteria that lack a true cell wall, are gram-negative, and require sterol for growth. »
A species of anaerobic, Gram-negative, pseudo-cocci shaped bacteria assigned to the phylum Firmicutes. This species is nonmotile, metabolizes arginine with the subsequent… »
A species of anaerobic, Gram-negative, pseudo-cocci shaped bacteria assigned to the phylum Firmicutes. This species is nonmotile, urease negative, does not hydrolyze… »
A species of anaerobic, Gram-negative, pseudo-cocci shaped bacteria assigned to the phylum Firmicutes. This species is motile, grows best in SP-4 medium… »
A taxonomic family of parasitic and pathogenic bacterium, which require sterols to grow, in the phylum Tenericutes that includes the genera Mycoplasma… »
A type of non-Hodgkin lymphoma that first appears on the skin and can spread to the lymph nodes or other organs such… »
A peripheral (mature) T-cell lymphoma presenting in the skin with patches/plaques and it is characterized by epidermal and dermal infiltration of small… »
Mature T and NK neoplasms predominantly affecting the skin and the peripheral blood. Peripheral blood involvement by abnormal T-cells (cerebriform cells)… »
A finding about one or more characteristics of mycosis fungoides and Sezary syndrome, following the rules of the TNM AJCC v7 classification… »
A finding about one or more characteristics of mycosis fungoides and Sezary syndrome, following the rules of the TNM AJCC v7 classification… »
A finding about one or more characteristics of mycosis fungoides and Sezary syndrome, following the rules of the TNM AJCC v7 classification… »
A flat, red area on the skin of patients who have mycosis fungoides. The patches may look like a thin, red rash… »
In mycosis fungoides, an area of skin that is thickened, raised, red, scaly, and itchy. »
A drug used to treat infections caused by fungi (a type of microorganism). It is made by certain strains of bacteria and… »
Mycotoxins are toxic, secondary metabolites of low molecular weight produced by naturally occurring fungi. Mycotoxins are neither infectious nor contagious, but… »
This gene is involved in the modulation of proinflammatory gene expression. »
Human MYD88 wild-type allele is located in the vicinity of 3p22 and is approximately 5 kb in length. This allele, which encodes… »
The fatty substance that covers and protects nerves. »
The determination of the amount of the myelin antibodies in a sample. »
Myelin protein zero-like protein 1 (269 aa, ~29 kDa) is encoded by the human MPZL1 gene. This protein is involved in both… »
Myelin proteolipid protein (277 aa, ~30 kDa) is encoded by the human PLP1 gene. This protein is involved in the structure of… »
A layer of phospholipids and protein found on neuronal axons. This structure acts as an electrical insulator that allows nerve impulses to… »
Myelin transcription factor 1-like protein (1186 aa, ~133 kDa) is encoded by the human MYT1L gene. This protein is involved in the… »
Axons of neurons encased in a lipoproteinaceous material called myelin. »
An inflammatory process affecting the spinal cord. Causes include viral infections, autoimmune disorders, vascular disorders, and toxic agents. Symptoms include weakness, paresthesia,… »
A severe form of myelosuppression. Myelosuppression is a condition in which bone marrow activity is decreased, resulting in fewer red blood cells,… »
Agents that destroy bone marrow activity. They are used to prepare patients for bone marrow or stem cell transplantation. »
High-dose chemotherapy that kills cells in the bone marrow, including cancer cells. It lowers the number of normal blood-forming cells in the… »
A type of immature white blood cell that forms in the bone marrow. Myeloblasts become mature white blood cells called granulocytes (neutrophils,… »
The determination of the number of myeloblast cells present in a sample. »
The determination of the ratio of myeloblasts compared to leukocytes in a blood sample. The measurement may be expressed as a ratio… »
The determination of the ratio of myeloblasts compared to total cells present in a sample. The measurement may be expressed as a… »
Refers to myeloblasts (a type of immature cell that forms in the bone marrow). »
Myeloblastin (256 aa, ~28 kDa) is encoded by the human PRTN3 gene. This protein is involved in the proteolysis of extracellular matrix… »
Herniation of spinal cord tissue and meninges through a defect in a region of the vertebral column. The protrusion of the tissue… »
A cell derived from a promyelocyte. It differentiates into a metamyelocyte. It has a diameter of 10-18 micrometer, and an oval or… »
The determination of the number of myelocyte cells present in a sample. »
The determination of the ratio of myelocytes compared to leukocytes in a blood sample. The measurement may be expressed as a ratio… »
The determination of the ratio of myelocytes compared to total cells present in a sample. The measurement may be expressed as a… »
Abnormal bone marrow cells that may lead to myelogenous leukemia. »
A type of cancer in which the bone marrow does not make enough healthy blood cells (white blood cells, red blood cells,… »
Myelodysplastic syndrome 2 translocation-associated protein (140 aa, ~15 kDa) is encoded by the human MDS2 gene. This protein plays a role in… »
A myelodysplastic syndrome characterized by the presence of a point mutation in one of the following genes, TP53, EZH2, ETV6, RUNX1, and… »
A myelodysplastic syndrome characterized by a deletion between bands q31 and 33 on chromosome 5. The number of blasts in the… »
A myelodysplastic syndrome characterized by neutropenia or thrombocytopenia and dysplasia restricted to neutrophil or megakaryocytic cell lines. The blasts in the… »
Your bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature… »
A category of clonal myeloid disorders that have both myelodysplastic and myeloproliferative features at the time of initial presentation. »
This entity includes cases that have clinical, laboratory, and morphologic features that support the diagnosis of both a myelodysplastic syndrome and a… »
A disorder in which the bone marrow is replaced by fibrous tissue. »
Having to do with, produced by, or resembling the bone marrow. Sometimes used as a synonym for myeloid; for example, acute myeloid… »
An x-ray of the spinal cord after an injection of dye into the space between the lining of the spinal cord and… »
The radiographic examination of the spinal cord and nerve roots following the injection of a contrast medium into the spinal subarachnoid… »
Having to do with or resembling the bone marrow. May also refer to certain types of hematopoietic (blood-forming) cells found in the… »
A group of rare myeloid and lymphoid neoplasms characterized by rearrangement of the PDGFRA, PDGFRB, or FGFR1 genes, resulting in the formation… »
Hematologic neoplasms characterized by the rearrangement of the FGFR1 gene, resulting in translocations with an 8p11 breakpoint. Patients present with a myeloproliferative… »
Hematologic neoplasms characterized by the rearrangement of the PDGFRA gene, most often resulting in the formation of FIP1L1-PDGFRA fusion transcripts. Patients usually… »
Cells which include the monocytes and the granulocytes. »
Myeloid Cell Activation involves stimulation of the production and activity of myeloid cells. Immature myeloid cells sample the surrounding environment for pathogens;… »
Any apoptotic process occurring in a neutrophil, eosinophil or basophil. »
The biological process that refers to the maturation of myelocytes. »
Myeloid cell surface antigen CD33 (364 aa, ~40 kDa) is encoded by the human CD33 gene. This protein is involved in the… »
Myeloid differentiation primary response protein MyD88 (296 aa, ~33 kDa) is encoded by the human MYD88 gene. This protein is involved in… »
Comment: Intended to encompass diseases more closely related to human myelodysplastic syndromes than to human myelodysplastic/myeloproliferative or myeloproliferative diseases; Disorder is not… »
A clonal proliferation of myeloid cells and their precursors in the bone marrow, peripheral blood, and spleen. When the proliferating cells are… »
Acute myeloid leukemia or myelodysplastic syndrome occurring in children with Down syndrome. The acute myeloid leukemia is usually an acute megakaryoblastic… »
Myeloid leukemia factor 1 (268 aa, ~31 kDa) is encoded by the human MLF1 gene. This protein plays a role in both… »
Myeloid leukemia not growing, responding to treatment. »
A clonal (malignant) proliferation of myeloid cells originating from a primitive stem cell. »
Myeloid neoplasms characterized by the rearrangement of the PDGFRB gene, most often resulting in the formation of ETV6-PDGFRB fusion transcripts. Patients usually… »
Myeloid neoplasms occurring in individuals with Down syndrome. There is an increased risk of acute leukemias in both children and adults… »
A tumor mass composed of myeloblasts or immature myeloid cells. It occurs in extramedullary sites or the bone. »
A myeloid sarcoma that is responding to therapy, i.e. is not progressing and possibly regressing. --2003 »
The determination of the ratio of myeloid cells compared to erythroid cells present in a sample. The measurement may be expressed as… »
Cancer that arises in plasma cells, a type of white blood cell. »
A vaccine consisting of myeloma-specific immunoglobulin conjugated to keyhole limpet hemocyanin (KLH), an immune stimulant, with potential antineoplastic activity. Vaccination with… »
A type of cancer that begins in plasma cells (white blood cells that produce antibodies). Also called Kahler disease, multiple myeloma, … »
A congenital abnormality in which the spinal cord and meninges protrude through a defect in the spinal column. The protrusion is above… »
An abnormal type of white blood cell that is found in chronic myelomonocytic leukemia. These cells are similar to both monocytes and… »
Myeloperoxidase (745 aa, ~84 kDa) is encoded by the human MPO gene. This protein is involved in the regulation of the innate… »
The determination of the amount of myeloperoxidase antibody present in a sample. »
The determination of the amount of myeloperoxidase present in a sample. »
The hematopoietic process that refers to the production of myelocytes. »
Myeloproliferation involves both medullary and extramedullary proliferation of bone marrow constituents, such as erythroblasts, granulocytes, megakaryocytes, and fibroblasts. »
A type of disease in which the bone marrow makes too many red blood cells, platelets, or certain white blood cells. Myeloproliferative… »
A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic,… »
This subgroup of myeloproliferative neoplasms includes cases which do not meet the morphologic criteria of any of the defined myeloproliferative neoplasms, or… »
A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as… »
A condition in which bone marrow activity is decreased, resulting in fewer red blood cells, white blood cells, and platelets. Myelosuppression is… »
Treatment that inhibits blood cell production. »
This gene plays a role in muscle contraction. »
Human MYH1 wild-type allele is located in the vicinity of 17p13.1 and is approximately 26 kb in length. This allele, which encodes… »
This gene plays a regulatory role in muscle contraction and the required ATP hydrolysis. »
Human MYH11 wild-type allele is located in the vicinity of 16p13.11 and is approximately 154 kb in length. This allele, which encodes… »
This gene is involved in skeletal muscle contraction. »
Human MYH2 wild-type allele is located in the vicinity of 17p13.1 and is approximately 85 kb in length. This allele, which encodes… »
This gene is involved in both cytoskeleton modeling and cytokinesis. »
Human MYH9 wild-type allele is located in the vicinity of 22q13.1 and is approximately 107 kb in length. This allele, which encodes… »
A commercial combination preparation, by Johnson & Johnson-Merck Consumer Pharmaceuticals, containing the antacids aluminum hydroxide and magnesium hydroxide. Aluminum hydroxide and magnesium… »
A drug used to treat chronic myelogenous leukemia (CML). It is also used with other drugs to prepare patients with CML for… »
This gene plays a role in smooth muscle contraction. »
Human MYLK wild-type allele is located within 3q21 and is approximately 272 kb in length. This allele, which encodes myosin light chain… »
A drug that is used to treat myelodysplastic syndromes and is being studied in the treatment of other types of cancer. It… »
Medicamento que se usa en el tratamiento de los síndromes mielodisplásicos y que está en estudio para el tratamiento de otros tipos… »
A monoclonal antibody combined with a toxic substance that is used to treat certain types of acute myeloid leukemia in older patients… »
Anticuerpo monoclonal combinado con una sustancia tóxica que se usa para tratar ciertos tipos de leucemia mieloide aguda en pacientes de edad… »
This gene is involved in cytoskeletal structure. »
Human MYO18A wild-type allele is located in the vicinity of 17q11.2 and is approximately 107 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(5;17)(q33-34;q11.2) which fuses exon 40 of the MYO18A gene to exon 10 of… »
A fusion protein encoded by the MYO18A/PDGFRB fusion gene. This protein is comprised of almost the entire myosin-XVIIIa protein fused to the… »
A muscle cell precursor. It is essential for muscle repair. »
Myoblast determination protein 1 (320 aa, ~35 kDa) is encoded by the human MYOD1 gene. This protein plays a role in DNA… »
Of or pertaining to the myocardium. »
Perfusion of blood through the myocardium. »
A bruise to the heart. »
Diseases of the myocardium. »
Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis. … »
An electrocardiographic finding of pathologic Q waves, which is suggestive of myocardial infarction of one or more regions of the heart. No… »
An electrocardiographic assessment of findings that suggest the occurrence of a myocardial infarction. »
An electrocardiographic finding of ST and T wave changes consistent with impaired myocardial perfusion. »
A procedure that captures pictures of blood flow throughout the heart muscle. »
Inflammation of the muscle tissue of the heart. »
The striated muscle tissue of the heart enveloped by the epicardium and the endocardium. »
A sudden, brief, strong contraction of a muscle or group of muscles that cannot be controlled. »
Myocyte-specific enhancer factor 2A (507 aa, ~55 kDa) is encoded by the human MEF2A gene. This protein plays a role in the… »
Myocyte-specific enhancer factor 2B (365 aa, ~39 kDa) is encoded by the human MEF2B gene. This protein is involved in transcription. … »
Myocyte-specific enhancer factor 2C (473 aa, ~51 kDa) is encoded by the human MEF2C gene. This protein plays a role in the… »
Myocyte-specific enhancer factor 2D (521 aa, ~56 kDa) is encoded by the human MEF2D gene. This protein plays a role in transcriptional… »
This gene plays a role in DNA binding and myogenesis. »
Human MYOD1 wild-type allele is located in the vicinity of 11p15.4 and is approximately 3 kb in length. This allele, which encodes… »
Derived from epithelial cells and destined to become a part of the muscular system; having the characteristics of both muscle and… »
A malignant neoplasm that has myoepithelial differentiation (generally detected by the mixture of glands and spindle cells and/or the presence of smooth… »
A malignant neoplasm primarily composed of a spindle cell stroma. May or may not have an identifiable glandular component. »
A contractile cell found between the secretory cells and basement membrane of exocrine glands. Each myoepithelial cell has long cytoplasmic processes that… »
A benign or malignant epithelial neoplasm characterized by the presence of cells that show myoepithelial differentiation. Based on its morphologic features, it… »
An inherited or sporadic disorder affecting the skeletal muscles. »
A spindle-shaped cell that exhibits characteristics of both fibroblasts and smooth muscle cells. It has an elongated nucleus and does not have… »
A morphologic finding that indicates the presence of myofibroblastic differentiation in a cellular infiltrate of a tissue sample. »
A benign, well circumscribed soft tissue neoplasm characterized by the presence of spindle shaped myofibroblasts and mast cells in a collagenous… »
A benign localized neoplasm arising from the subcutaneous tissues and skeletal muscle. It is characterized by the presence of myofibroblastic hyperchromatic spindle… »
A benign neoplasm arising from the soft tissues. It is characterized by the presence of myofibroblastic hyperchromatic spindle cells, hylanized stroma formation,… »
Fibrillar protein polymers found in the contractile apparatus of muscle cells. »
This gene is involved in muscle differentiation and transcription. »
Human MYOG wild-type allele is located within 1q31-q41 and is approximately 3 kb in length. This allele, which encodes myogenin protein, plays… »
Embryonic formation of muscle cells or fibers. »
Myogenin (224 aa, ~25 kDa) is encoded by the human MYOG gene. This protein is involved in both transcription and myogenesis. … »
The determination of the amount of myoglobin present in a sample. »
The determination of the ratio of myoglobin compared to creatinine present in a sample. The measurement may be expressed as a ratio… »
A morphologic variant of dermatofibrosarcoma protuberans characterized by the presence of areas of myofibroblastic differentiation. »
The portion of the inner segment of a photoreceptor cell between the ellipsoid portion and the nucleus that is rich in ribonucleic… »
A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Myoinositol helps cells… »
A disorder characterized by involuntary and irregular muscle contractions not associated with muscle weakness or atrophy. It most often affects facial… »