MMI270

An orally-active synthetic hydroxamic acid derivative with potential antineoplastic activity. MMI270 inhibits a broad spectrum of matrix metalloproteinases (MMPs) (specifically MMP-1, 2, 3, 9, and 13), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent may also downregulate lymphangiogenesis, resulting in decreased lymphatic system-related metastasis. (NCI Thesaurus)

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Human MME wild-type allele is located within 3q25.1-q25.2 and is approximately 104 kb in length. This allele, which encodes neprilysin protein, plays…

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MMADHC wt Allele

Human MMADHC wild-type allele is located in the vicinity of 2q23.2 and is approximately 18 kb in length. This allele, which encodes…

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mM

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MLXIPL wt Allele

Human MLXIPL wild-type allele is located in the vicinity of 7q11.23 and is approximately 31 kb in length. This allele, which encodes…