| Health / Medical Topics |
Oncogenes, Tyrosine-Kinase
Activated forms of tyrosine kinase family proto-oncogenes that contribute to the development of cancer. These proto-oncogenes encode tyrosine kinase proteins, which are enzymes that play a major role in mitogenic signaling by catalyzing the phosphorylation of tyrosine residues in proteins. Tyrosine kinase oncogenes exhibit aberrant gene expression, resulting in elevated levels of their protein products which disrupts mitotic checkpoints. (NCI Thesaurus)
YOU MAY ALSO LIKE
Human Protein-Kinase Oncogenes are mutated variants of Kinase Family Genes, which encode diverse Protein Kinases. Protein kinase enzymes catalyze the conversion of…
Any oncogene (cancer-causing gene) that is derived from a proto-oncogene (normal gene) which has an unknown or unclassified cellular function. Genetic mutations…
Oncogenes that encode nuclear proteins.
Mutated forms of growth factor genes which encode a diverse group of extracellular regulatory growth factor signaling molecules. These protein products play…
Mutated forms of G-protein genes which encode a diverse group of regulatory proteins that act as molecular switches. Under normal cellular conditions,…
Transcription factors that are encoded by oncogenes, a type of gene that contributes to the development of the malignant phenotype of a…
