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Osteosarcoma
Pronunciation
Definition 1
A cancer of the bone that usually affects the large bones of the arm or leg. It occurs most commonly in young people and affects more males than females. Also called osteogenic sarcoma. (NCI Dictionary)
Definition 2
A usually aggressive malignant bone-forming mesenchymal tumor, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom. It may spread to other anatomic sites, particularly the lungs. (NCI Thesaurus)
Definition 3
A malignant neoplasm usually arising from bone. (NCI Thesaurus/CDISC)
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