Health / Medical Topics

    Pleomorphic Rhabdomyosarcoma

    Definition 1

    An aggressive malignant mesenchymal neoplasm with skeletal muscle differentiation, occurring in adults and rarely in children. The tumor is characterized by the presence of bizarre round, spindle, and polygonal cells. Clinical presentation includes a rapidly enlarging painful mass usually of the lower extremities. (NCI Thesaurus)

    Definition 2

    A high grade sarcoma occurring almost exclusively in adults and consisting of bizarre polygonal, round and spindle cells which display evidence of skeletal muscle differentiation. (NCI Thesaurus)




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