Health / Medical Topics

    POLD1 wt Allele

    Human POLD1 wild-type allele is located in the vicinity of 19q13.3 and is approximately 34 kb in length. This allele, which encodes DNA polymerase delta catalytic subunit protein, plays a role in DNA replication. Mutation of the gene may be associated with increased susceptibility to colorectal malignancies. (NCI Thesaurus)




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