Library / English Dictionary

POLYMERASE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

An enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA

Classified under:

Nouns denoting substances

Hypernyms ("polymerase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

Hyponyms (each of the following is a kind of "polymerase"):

DNA polymerase (the enzyme responsible for DNA replication)

RNA polymerase; transcriptase (the enzyme that copies DNA into RNA)

reverse transcriptase (a polymerase that catalyzes the formation of DNA using RNA as a template; found especially in retroviruses)

Credits

 Context examples: 

This allele, which encodes myc proto-oncogene protein, plays a role in the regulation of transcription by RNA polymerase II.

(MYC wt Allele, NCI Thesaurus)

This allele, which encodes L-myc-1 proto-oncogene protein, is involved in modulation of transcription by RNA polymerase II.

(MYCL1 wt Allele, NCI Thesaurus)

This allele, which encodes nuclear factor NF-kappa-B p100 subunit protein, is involved in the modulation of transcription by RNA polymerase II.

(NFKB2 wt Allele, NCI Thesaurus)

This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.

(Niacinamide, NCI Thesaurus)

An inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity.

(Niraparib, NCI Thesaurus)

This allele, which encodes homeobox protein Nkx-2.8, is involved in the modulation of transcription by RNA polymerase II in several developmental processes.

(NKX2-8 wt Allele, NCI Thesaurus)

This allele, which encodes nuclear factor 1 X-type protein, plays a role in both the modulation of transcription by RNA polymerase II and the activation of DNA replication.

(NFIX wt Allele, NCI Thesaurus)

This allele, which encodes nuclear factor 1 C-type protein, plays a role in both the modulation of transcription by RNA polymerase II and the activation of DNA replication.

(NFIC wt Allele, NCI Thesaurus)

This allele, which encodes N-myc proto-oncogene protein, is involved in the modulation of transcription by RNA polymerase II.

(MYCN wt Allele, NCI Thesaurus)

Nesbuvir binds to the palm site II pocket of HCV NS5B polymerase and inhibits viral genome replication.

(Nesbuvir, NCI Thesaurus)