Health / Medical Topics

    Pri-miRNA

    Definition 1

    The pri-miRNA is a primary transcript derived from a gene whose sole products are miRNA(s). A unique pathway involving the nuclear microprocessor complex participates in the cleavage of such transcripts, which can be substantially longer than the 65-110 nt pre-miRNA. (NCI Thesaurus)

    Definition 2

    A reverse-complement DNA sequence that is transcribed into a single-stranded RNA molecule. The microRNA (miRNA) sequence and its reverse-complement base pair to form a double stranded RNA hairpin loop; this pairing forms a primary miRNA structure referred to as pri-miRNA. (NCI Thesaurus)




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