| Health / Medical Topics |
Pteridines, Folic Acid Analogs
Folic acid analogs containing a pteridine base, a two-ring heterocyclic aromatic compound, and are used to interfere with folic acid. (NCI Thesaurus)
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PTEN is a tumor suppressor gene. Recombinant PTEN is capable of dephosphorylating phosphatidylinositol 3,4,5-triphosphate[PI(3,4,5)P3], the product of phosphatidylinositol 3-kinase. Many of the…
Human PTEN wild type allele is located in the vicinity of 10q23.3 and is approximately 109 kb in length. This allele, which…
A protein that helps control many cell functions, including cell division and cell death. Mutations (changes) in the gene that makes PTEN…
A molecular abnormality referring to the loss of at least one copy of the PTEN gene (10q23).
A molecular genetic abnormality indicating the presence of an inactivating mutation in the PTEN gene on chromosome 10q23.
This gene plays a role in signal transduction and apoptosis. It is also involved in the regulation of cell cycle progression. …
