PTPRC wt Allele

Human PTPRC wild-type allele is located in the vicinity of 1q31-q32 and is approximately 118 kb in length. This allele, which encodes leukocyte common antigen protein, plays a role in T-cell activation through the antigen receptor. Defects in the PTPRC gene are a cause of autosomal recessive severe combined immunodeficiency (SCID). (NCI Thesaurus)

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PTPRC Gene

This gene plays a role in suppression of cytokine receptor signaling and the regulation of signal transduction in lymphocytes.

PTPN7 wt Allele

Human PTPN7 wild-type allele is located in the vicinity of 1q32.1 and is approximately 15 kb in length. This allele, which encodes…

PTPN7 Gene

This gene plays a role in regulation of lymphocyte development and suppression of signal transduction.

PTPN6 wt Allele

Human PTPN6 wild-type allele is located within 12p13 and is approximately 29 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor…

PTPN6 Gene

This gene plays a role in the regulation of multiple signaling pathways in hematopoietic cells.

PTPN22 wt Allele

Human PTPN22 wild-type allele is located within 1p13.3-p13.1 and is approximately 123 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor…