| Health / Medical Topics |
RUNX1/SH3D19 Fusion Gene
A fusion gene that results from a chromosomal translocation t(4;21)(q31.1;q22) which fuses exon 5 or 6 of the RUNX1 gene to exon 2 of the SH3D19 gene. This rearrangement is associated with one case of acute myeloid leukemia. (NCI Thesaurus)
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A fusion protein (752 aa, ~83 kDa) encoded by the RUNX1/RUNX1T1 fusion gene. This protein is comprised of the N-terminal runt domain…
A fusion gene (~4.3 kb) that results from a chromosomal translocation t(8;21)(q22;q22) which fuses the first 5 exons of the RUNX1 gene…
A fusion protein (1395 aa, ~156 kDa) encoded by the RUNX1/MECOM fusion gene. This protein is comprised of the N-terminal runt domain…
A fusion gene (~5.9 kb) that results from a chromosomal translocation t(3;21)(q26;q22) which fuses the first 5 exons of the RUNX1 gene…
Human RUNX1 wild-type allele is located in the vicinity of 21q22.3 and is approximately 262 kb in length. This allele, which encodes…
This gene plays a role in transcriptional regulation and cytogenetic aberrations are associated with several leukemias.
